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Accession:CHEBI:9620 term browser browse the term
Definition:A monothiocarbamic ester that is the methyl(3-tolyl)carbamothioate ester of 2-naphthol. A synthetic anti-fungal agent used to treat jock itch, athlete's foot and ringworm.
Synonyms:exact_synonym: O-2-naphthyl methyl(3-methylphenyl)carbamothioate
 related_synonym: 2-Naphthyl N-methyl-N-(3-tolyl)thionocarbamate;   Formula=C19H17NOS;   InChI=1S/C19H17NOS/c1-14-6-5-9-17(12-14)20(2)19(22)21-18-11-10-15-7-3-4-8-16(15)13-18/h3-13H,1-2H3;   InChIKey=FUSNMLFNXJSCDI-UHFFFAOYSA-N;   Methyl (3-methylphenyl)carbamothioic acid O-2-naphthalenyl ester;   N-methyl-N-(3-methylphenyl)-1-(naphthalen-2-yloxy)methanethioamide;   O-2-Naphthyl m,N-dimethylthiocarbanilate;   SMILES=CN(C(=S)Oc1ccc2ccccc2c1)c1cccc(C)c1;   Separin;   Tinactin;   Tolnaphthate;   m,N-Dimethylthiocarbanilic acid O-2-naphthyl ester;   tolnaftato;   tolnaftatum
 xref: CAS:2398-96-1 "ChemIDplus";   CAS:2398-96-1 "KEGG DRUG";   CAS:2398-96-1 "NIST Chemistry WebBook";   DrugBank:DB00525;   Drug_Central:3617 "DrugCentral";   HMDB:HMDB0005005;   KEGG:D00381;   LINCS:LSM-5554
 xref_mesh: MESH:D014047
 xref: PMID:20347664 "Europe PMC";   PMID:2061794 "Europe PMC";   PMID:20635527 "Europe PMC";   PMID:21565546 "Europe PMC";   PMID:22125963 "Europe PMC";   PMID:24706116 "Europe PMC";   PMID:3509341 "Europe PMC";   PMID:4568708 "Europe PMC";   PMID:5319027 "Europe PMC";   PMID:5705341 "Europe PMC";   PMID:5745067 "Europe PMC";   PMID:5847820 "Europe PMC";   PMID:5856396 "Europe PMC";   PMID:5952516 "Europe PMC";   PMID:697362 "Europe PMC";   Patent:US2010035939;   Patent:WO2010037089;   Reaxys:2752620 "Reaxys";   Wikipedia:Tolnaftate

show annotations for term's descendants       view all columns           Sort by:
tolnaftate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gli1 GLI family zinc finger 1 JBrowse link 7 70,620,794 70,633,171 RGD:6480464
G Gstp1 glutathione S-transferase pi 1 JBrowse link 1 219,291,679 219,294,147 RGD:6480464
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:6480464
G Il5 interleukin 5 JBrowse link 10 39,066,716 39,069,587 RGD:6480464
G Shh sonic hedgehog signaling molecule JBrowse link 4 718,538 727,691 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19654
    role 19598
      biological role 19596
        aetiopathogenetic role 18752
          genotoxin 16036
            2-naphthol 37
              tolnaftate 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19654
    subatomic particle 19650
      composite particle 19650
        hadron 19650
          baryon 19650
            nucleon 19650
              atomic nucleus 19650
                atom 19650
                  main group element atom 19531
                    main group molecular entity 19531
                      s-block molecular entity 19314
                        hydrogen molecular entity 19303
                          hydrides 18231
                            organic hydride 17520
                              organic fundamental parent 17520
                                hydrocarbon 16926
                                  cyclic hydrocarbon 15090
                                    arene 15077
                                      polycyclic arene 14508
                                        ortho-fused polycyclic arene 9530
                                          ortho-fused bicyclic arene 2375
                                            naphthalene 2323
                                              naphthol 185
                                                2-naphthol 37
                                                  tolnaftate 5
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.