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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:drimane
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Accession:CHEBI:36474 term browser browse the term
Definition:A terpenoid fundamental parent that has formula C15H28.
Synonyms:related_synonym: (4aR,5S,6S,8aS)-1,1,4a,5,6-pentamethyldecahydronaphthalene;   Formula=C15H28;   InChI=1S/C15H28/c1-11-7-8-13-14(3,4)9-6-10-15(13,5)12(11)2/h11-13H,6-10H2,1-5H3/t11-,12-,13-,15+/m0/s1;   InChIKey=CVRSZZJUWRLRDE-PWNZVWSESA-N;   SMILES=[H][C@@]12CC[C@H](C)[C@H](C)[C@@]1(C)CCCC2(C)C
 xref: Beilstein:2959385


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(+)-albicanol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 multiple interactions ISO albicanol inhibits the reaction [Galactose results in increased expression of CASP3 mRNA] CTD PMID:33761044 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp9 caspase 9 multiple interactions ISO albicanol inhibits the reaction [Galactose results in increased expression of CASP9 mRNA] CTD PMID:33761044 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cat catalase multiple interactions ISO albicanol inhibits the reaction [Galactose results in decreased activity of CAT protein] CTD PMID:33761044 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO albicanol inhibits the reaction [Galactose results in decreased expression of HMOX1 protein] CTD PMID:33761044 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO albicanol inhibits the reaction [Galactose results in increased expression of IL1B mRNA] CTD PMID:33761044 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 multiple interactions ISO albicanol inhibits the reaction [Galactose results in increased expression of KEAP1 mRNA]; albicanol inhibits the reaction [Galactose results in increased expression of KEAP1 protein] CTD PMID:33761044 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions ISO albicanol inhibits the reaction [Galactose results in decreased expression of NFE2L2 mRNA]; albicanol inhibits the reaction [Galactose results in decreased expression of NFE2L2 protein] CTD PMID:33761044 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO albicanol inhibits the reaction [Galactose results in decreased expression of NQO1 protein] CTD PMID:33761044 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions ISO albicanol inhibits the reaction [Galactose results in decreased expression of SOD2 protein] CTD PMID:33761044 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO albicanol inhibits the reaction [Galactose results in increased expression of TNF mRNA] CTD PMID:33761044 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
drimenol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator increases expression ISO drimenol results in increased expression of BAX protein CTD PMID:30935903 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO drimenol results in decreased expression of BCL2 protein CTD PMID:30935903 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Casp3 caspase 3 increases activity ISO drimenol results in increased activity of CASP3 protein CTD PMID:30935903 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp9 caspase 9 increases cleavage ISO drimenol results in increased cleavage of CASP9 protein CTD PMID:30935903 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19808
    chemical entity 19806
      atom 19806
        nonmetal atom 19744
          carbon atom 19702
            organic molecular entity 19702
              organic fundamental parent 18669
                natural product fundamental parent 14976
                  terpenoid fundamental parent 3915
                    drimane 12
                      (+)-albicanol 10
                      drimendiol 0
                      drimenol + 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19806
      composite particle 19806
        hadron 19806
          baryon 19806
            nucleon 19806
              atomic nucleus 19806
                atom 19806
                  main group element atom 19756
                    main group molecular entity 19756
                      s-block molecular entity 19595
                        hydrogen molecular entity 19582
                          hydrides 19095
                            organic hydride 18669
                              organic fundamental parent 18669
                                hydrocarbon 18415
                                  terpene 14057
                                    sesquiterpene 3270
                                      drimane 12
                                        (+)-albicanol 10
                                        drimendiol 0
                                        drimenol + 4
paths to the root