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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:Benzyl parahydroxybenzoate
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Accession:CHEBI:34571 term browser browse the term
Definition:A benzyl ester that has formula C14H12O3.
Synonyms:related_synonym: Benzyl 4-hydroxybenzoate;   Benzylparaben;   Formula=C14H12O3;   InChI=1S/C14H12O3/c15-13-8-6-12(7-9-13)14(16)17-10-11-4-2-1-3-5-11/h1-9,15H,10H2;   InChIKey=MOZDKDIOPSPTBH-UHFFFAOYSA-N;   SMILES=C1=CC(=CC=C1C(=O)OCC2=CC=CC=C2)O
 xref: CAS:94-18-8;   KEGG:C14393;   KEGG:D07518
 xref_mesh: MESH:C057775


show annotations for term's descendants           Sort by:
Benzyl parahydroxybenzoate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADIPOQ adiponectin, C1Q and collagen domain containing increases expression EXP
ISO		 benzylparaben results in increased expression of ADIPOQ mRNA CTD PMID:22956630 NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463 		JBrowse link
G AFP alpha fetoprotein affects binding ISO benzylparaben binds to AFP protein CTD PMID:23013281 PMID:25349334 NCBI chr 4:73,436,221...73,456,174
Ensembl chr 4:73,431,138...73,456,174 		JBrowse link
G CEBPA CCAAT enhancer binding protein alpha increases expression ISO benzylparaben results in increased expression of CEBPA mRNA CTD PMID:22956630 PMID:27659731 NCBI chr19:33,299,934...33,302,534
Ensembl chr19:33,299,934...33,302,534 		JBrowse link
G ESR1 estrogen receptor 1 multiple interactions EXP benzylparaben binds to and results in increased activity of ESR1 protein CTD PMID:23220609 PMID:23567241 NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619 		JBrowse link
G ESR2 estrogen receptor 2 multiple interactions EXP benzylparaben binds to and results in increased activity of ESR2 protein CTD PMID:23567241 NCBI chr14:64,226,707...64,338,613
Ensembl chr14:64,084,232...64,338,112 		JBrowse link
G ESRRG estrogen related receptor gamma multiple interactions EXP benzylparaben inhibits the reaction [afimoxifene inhibits the reaction [ESRRG protein binds to NCOA2 protein]] CTD PMID:23583298 NCBI chr 1:216,503,246...217,137,702
Ensembl chr 1:216,503,246...217,137,755 		JBrowse link
G FAAH fatty acid amide hydrolase decreases activity EXP
ISO		 benzylparaben results in decreased activity of FAAH protein CTD PMID:27659731 NCBI chr 1:46,394,317...46,413,845
Ensembl chr 1:46,394,317...46,413,848 		JBrowse link
G FABP4 fatty acid binding protein 4 increases expression EXP
ISO		 benzylparaben results in increased expression of FABP4 mRNA CTD PMID:22956630 PMID:27659731 NCBI chr 8:81,478,419...81,483,233
Ensembl chr 8:81,478,419...81,483,236 		JBrowse link
G FASN fatty acid synthase increases expression EXP
ISO		 benzylparaben results in increased expression of FASN mRNA CTD PMID:22956630 NCBI chr17:82,078,338...82,098,236
Ensembl chr17:82,078,338...82,098,294 		JBrowse link
G LEP leptin decreases expression
increases expression		 EXP
ISO		 benzylparaben results in decreased expression of LEP mRNA
benzylparaben results in increased expression of LEP mRNA		 CTD PMID:22956630 NCBI chr 7:128,241,278...128,257,629
Ensembl chr 7:128,241,278...128,257,629 		JBrowse link
G NCOA2 nuclear receptor coactivator 2 multiple interactions EXP benzylparaben inhibits the reaction [afimoxifene inhibits the reaction [ESRRG protein binds to NCOA2 protein]] CTD PMID:23583298 NCBI chr 8:70,109,782...70,456,446
Ensembl chr 8:70,109,782...70,403,808 		JBrowse link
G NR1I2 nuclear receptor subfamily 1 group I member 2 increases expression EXP benzylparaben results in increased expression of NR1I2 mRNA CTD PMID:31472229 NCBI chr 3:119,782,101...119,818,487
Ensembl chr 3:119,780,484...119,818,487 		JBrowse link
G NR1I3 nuclear receptor subfamily 1 group I member 3 increases activity EXP benzylparaben results in increased activity of NR1I3 protein CTD PMID:28927721 NCBI chr 1:161,229,669...161,238,203
Ensembl chr 1:161,229,666...161,238,244 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha increases expression ISO benzylparaben results in increased expression of PPARA mRNA CTD PMID:31472229 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma increases expression
increases activity		 ISO benzylparaben results in increased expression of PPARG mRNA
benzylparaben results in increased activity of PPARG protein		 CTD PMID:22956630 PMID:27659731 PMID:28527915 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356 		JBrowse link
G SHBG sex hormone binding globulin affects binding EXP benzylparaben binds to SHBG protein CTD PMID:25349334 NCBI chr17:7,614,064...7,633,372
Ensembl chr17:7,613,946...7,633,382 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26040
    role 25956
      chemical role 24245
        antioxidant 17490
          benzyl alcohol 443
            benzyl ester 391
              Benzyl parahydroxybenzoate 16
Path 2
Term Annotations click to browse term
  CHEBI ontology 26040
    subatomic particle 26015
      composite particle 26015
        hadron 26015
          baryon 26015
            nucleon 26015
              atomic nucleus 26015
                atom 26015
                  main group element atom 25840
                    p-block element atom 25840
                      carbon group element atom 25437
                        carbon atom 25395
                          organic molecular entity 25395
                            heteroorganic entity 24770
                              organochalcogen compound 24383
                                organooxygen compound 24060
                                  carbon oxoacid 22761
                                    carboxylic acid 22741
                                      aromatic carboxylic acid 13389
                                        benzoic acids 13363
                                          benzoate ester 5853
                                            Benzyl parahydroxybenzoate 16
paths to the root