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G |
Akr1b1 |
aldo-keto reductase family 1 member B1 |
increases oxidation |
ISO |
AKR1B1 protein results in increased oxidation of Benzyl Alcohol |
CTD |
PMID:17194029 |
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NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157
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G |
Il1a |
interleukin 1 alpha |
increases expression |
ISO |
Benzyl Alcohol results in increased expression of IL1A protein |
CTD |
PMID:19878710 |
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NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
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G |
Lif |
LIF, interleukin 6 family cytokine |
increases expression |
ISO |
Benzyl Alcohol results in increased expression of LIF protein |
CTD |
PMID:19878710 |
|
NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482
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G |
Sult1a1 |
sulfotransferase family 1A member 1 |
increases sulfation |
ISO |
SULT1A1 protein results in increased sulfation of Benzyl Alcohol |
CTD |
PMID:26663444 |
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NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562
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G |
Sult1b1 |
sulfotransferase family 1B member 1 |
increases sulfation |
ISO |
SULT1B1 protein results in increased sulfation of Benzyl Alcohol |
CTD |
PMID:26663444 |
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NCBI chr14:20,492,763...20,505,491
Ensembl chr14:20,492,708...20,505,483
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G |
Ugt2b1 |
UDP glucuronosyltransferase 2 family, polypeptide B1 |
increases glucuronidation |
EXP |
UGT2B1 protein results in increased glucuronidation of Benzyl Alcohol |
CTD |
PMID:8302279 |
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NCBI chr14:21,024,035...21,035,784
Ensembl chr14:21,024,006...21,035,986
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G |
Enpp2 |
ectonucleotide pyrophosphatase/phosphodiesterase 2 |
increases expression |
ISO |
benzyl acetate results in increased expression of ENPP2 mRNA; benzyl acetate results in increased expression of ENPP2 protein |
CTD |
PMID:22952646 |
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NCBI chr 7:86,202,345...86,325,050
Ensembl chr 7:86,202,350...86,324,827
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G |
Mmp9 |
matrix metallopeptidase 9 |
increases expression |
ISO |
benzyl acetate results in increased expression of MMP9 mRNA; benzyl acetate results in increased expression of MMP9 protein |
CTD |
PMID:22952646 |
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NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
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G |
Ppp3ca |
protein phosphatase 3 catalytic subunit alpha |
multiple interactions |
ISO |
benzyl acetate results in increased cleavage of and results in increased activity of PPP3CA protein |
CTD |
PMID:22952646 |
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NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974
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G |
Atf3 |
activating transcription factor 3 |
increases expression |
ISO |
benzyl benzoate results in increased expression of ATF3 mRNA |
CTD |
PMID:27965148 |
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NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
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G |
Cd86 |
CD86 molecule |
increases expression |
ISO |
benzyl benzoate results in increased expression of CD86 protein |
CTD |
PMID:29540657 |
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NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
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G |
Esr1 |
estrogen receptor 1 |
multiple interactions |
ISO |
benzyl benzoate inhibits the reaction [Estradiol binds to ESR1 protein] |
CTD |
PMID:19338011 |
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NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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G |
Esr2 |
estrogen receptor 2 |
multiple interactions |
ISO |
benzyl benzoate inhibits the reaction [Estradiol binds to ESR2 protein] |
CTD |
PMID:19338011 |
|
NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
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G |
Maoa |
monoamine oxidase A |
decreases activity |
ISO |
benzyl benzoate results in decreased activity of MAOA protein |
CTD |
PMID:27270453 |
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NCBI chr X:6,032,172...6,098,308
Ensembl chr X:6,030,795...6,099,593
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G |
Maob |
monoamine oxidase B |
decreases activity |
ISO |
benzyl benzoate results in decreased activity of MAOB protein |
CTD |
PMID:27270453 |
|
NCBI chr X:5,907,327...6,010,996
Ensembl chr X:5,907,266...6,011,003
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G |
Nefh |
neurofilament heavy chain |
affects expression |
EXP |
benzyl benzoate affects the expression of NEFH mRNA |
CTD |
PMID:22954530 |
|
NCBI chr14:79,830,362...79,840,347
Ensembl chr14:79,830,362...79,840,351
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G |
Tff1 |
trefoil factor 1 |
increases expression |
ISO |
benzyl benzoate results in increased expression of TFF1 mRNA |
CTD |
PMID:19338011 |
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NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597
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G |
Adipoq |
adiponectin, C1Q and collagen domain containing |
increases expression |
ISO |
benzylparaben results in increased expression of ADIPOQ mRNA |
CTD |
PMID:22956630 |
|
NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
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G |
Afp |
alpha-fetoprotein |
affects binding |
EXP |
benzylparaben binds to AFP protein |
CTD |
PMID:23013281 PMID:25349334 |
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NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480
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G |
Cebpa |
CCAAT/enhancer binding protein alpha |
increases expression |
ISO |
benzylparaben results in increased expression of CEBPA mRNA |
CTD |
PMID:22956630 PMID:27659731 |
|
NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
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G |
Esr1 |
estrogen receptor 1 |
multiple interactions |
ISO |
benzylparaben binds to and results in increased activity of ESR1 protein |
CTD |
PMID:23220609 PMID:23567241 |
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NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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G |
Esr2 |
estrogen receptor 2 |
multiple interactions |
ISO |
benzylparaben binds to and results in increased activity of ESR2 protein |
CTD |
PMID:23567241 |
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NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
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G |
Esrrg |
estrogen-related receptor gamma |
multiple interactions |
ISO |
benzylparaben inhibits the reaction [afimoxifene inhibits the reaction [ESRRG protein binds to NCOA2 protein]] |
CTD |
PMID:23583298 |
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NCBI chr13:99,167,656...99,788,016
Ensembl chr13:99,564,669...99,783,397
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G |
Faah |
fatty acid amide hydrolase |
decreases activity |
ISO EXP |
benzylparaben results in decreased activity of FAAH protein |
CTD |
PMID:27659731 |
|
NCBI chr 5:129,479,774...129,499,018
Ensembl chr 5:129,479,824...129,498,677
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G |
Fabp4 |
fatty acid binding protein 4 |
increases expression |
ISO |
benzylparaben results in increased expression of FABP4 mRNA |
CTD |
PMID:22956630 PMID:27659731 |
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NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578
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G |
Fasn |
fatty acid synthase |
increases expression |
ISO |
benzylparaben results in increased expression of FASN mRNA |
CTD |
PMID:22956630 |
|
NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
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G |
Lep |
leptin |
decreases expression increases expression |
ISO |
benzylparaben results in decreased expression of LEP mRNA benzylparaben results in increased expression of LEP mRNA |
CTD |
PMID:22956630 |
|
NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
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G |
Ncoa2 |
nuclear receptor coactivator 2 |
multiple interactions |
ISO |
benzylparaben inhibits the reaction [afimoxifene inhibits the reaction [ESRRG protein binds to NCOA2 protein]] |
CTD |
PMID:23583298 |
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NCBI chr 5:5,835,642...6,069,693
Ensembl chr 5:5,835,706...6,067,451
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G |
Nr1i2 |
nuclear receptor subfamily 1, group I, member 2 |
increases expression |
ISO |
benzylparaben results in increased expression of NR1I2 mRNA |
CTD |
PMID:31472229 |
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NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
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G |
Nr1i3 |
nuclear receptor subfamily 1, group I, member 3 |
increases activity |
ISO |
benzylparaben results in increased activity of NR1I3 protein |
CTD |
PMID:28927721 |
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NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
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G |
Ppara |
peroxisome proliferator activated receptor alpha |
increases expression |
EXP |
benzylparaben results in increased expression of PPARA mRNA |
CTD |
PMID:31472229 |
|
NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
increases expression increases activity |
ISO |
benzylparaben results in increased expression of PPARG mRNA benzylparaben results in increased activity of PPARG protein |
CTD |
PMID:22956630 PMID:27659731 PMID:28527915 |
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NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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G |
Shbg |
sex hormone binding globulin |
affects binding |
ISO |
benzylparaben binds to SHBG protein |
CTD |
PMID:25349334 |
|
NCBI chr10:54,332,939...54,350,409
Ensembl chr10:54,332,941...54,351,057
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G |
A4galt |
alpha 1,4-galactosyltransferase (P blood group) |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of A4GALT mRNA |
CTD |
PMID:31199487 |
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NCBI chr 7:114,368,525...114,392,872
Ensembl chr 7:114,368,276...114,396,071
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G |
Abcc3 |
ATP binding cassette subfamily C member 3 |
increases expression |
ISO |
butylbenzyl phthalate results in increased expression of ABCC3 mRNA |
CTD |
PMID:26519955 |
|
NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
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G |
Abcg2 |
ATP binding cassette subfamily G member 2 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of ABCG2 mRNA |
CTD |
PMID:31199487 |
|
NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
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G |
Acaca |
acetyl-CoA carboxylase alpha |
multiple interactions |
ISO |
[1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased expression of ACACA protein |
CTD |
PMID:26820058 |
|
NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
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G |
Acot1 |
acyl-CoA thioesterase 1 |
increases expression |
ISO |
butylbenzyl phthalate results in increased expression of ACOT1 mRNA |
CTD |
PMID:26519955 |
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NCBI chr 6:103,636,173...103,644,167
Ensembl chr 6:103,636,041...103,644,163
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G |
Adamts1 |
ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
multiple interactions |
ISO |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the reaction [CGA protein results in increased expression of ADAMTS1 mRNA]; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] inhibits the reaction [CGA protein results in increased expression of ADAMTS1 mRNA] |
CTD |
PMID:33316053 |
|
NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103
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G |
Adipoq |
adiponectin, C1Q and collagen domain containing |
multiple interactions |
ISO |
[1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased expression of ADIPOQ mRNA; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased expression of ADIPOQ protein; [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with Diethylhexyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisononyl phthalate] results in increased expression of ADIPOQ mRNA; butylbenzyl phthalate promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of ADIPOQ mRNA]; Curcumin inhibits the reaction [butylbenzyl phthalate promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of ADIPOQ mRNA]] butylbenzyl phthalate promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of and results in increased secretion of ADIPOQ protein]; butylbenzyl phthalate promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased secretion of ADIPOQ protein]; butylbenzyl phthalate promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ protein] |
CTD |
PMID:26820058 PMID:28595985 PMID:31016361 PMID:32407875 PMID:34864131 PMID:37021957 More...
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NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
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G |
Adrb3 |
adrenoceptor beta 3 |
multiple interactions |
ISO |
[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with Diethylhexyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisononyl phthalate] results in decreased expression of ADRB3 mRNA |
CTD |
PMID:37021957 |
|
NCBI chr16:64,839,820...64,844,552
Ensembl chr16:64,841,788...64,844,552
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G |
Ahr |
aryl hydrocarbon receptor |
affects localization multiple interactions increases expression affects activity |
ISO |
butylbenzyl phthalate affects the localization of AHR protein 3',4'-dimethoxyflavone inhibits the reaction [butylbenzyl phthalate results in increased expression of AHR mRNA]; 3',4'-dimethoxyflavone inhibits the reaction [butylbenzyl phthalate results in increased expression of AHR protein]; AHR mutant form inhibits the reaction [butylbenzyl phthalate results in increased expression of ARNT mRNA]; AHR mutant form inhibits the reaction [butylbenzyl phthalate results in increased expression of ARNT protein]; AHR mutant form inhibits the reaction [butylbenzyl phthalate results in increased expression of CYP1B1 mRNA]; AHR mutant form inhibits the reaction [butylbenzyl phthalate results in increased expression of CYP1B1 protein]; butylbenzyl phthalate binds to and results in increased activity of AHR protein; butylbenzyl phthalate promotes the reaction [AHR protein binds to ARNT protein]; butylbenzyl phthalate promotes the reaction [AHR protein binds to CYP1B1 promoter] butylbenzyl phthalate results in increased expression of AHR mRNA; butylbenzyl phthalate results in increased expression of AHR protein butylbenzyl phthalate affects the activity of AHR protein |
CTD |
PMID:18294747 PMID:22138065 PMID:23220035 |
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NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
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G |
Ak5 |
adenylate kinase 5 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of AK5 mRNA |
CTD |
PMID:31199487 |
|
NCBI chr 2:241,397,297...241,581,483
Ensembl chr 2:241,397,297...241,581,458
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G |
Akt1 |
AKT serine/threonine kinase 1 |
increases phosphorylation multiple interactions affects phosphorylation decreases phosphorylation |
ISO EXP |
butylbenzyl phthalate results in increased phosphorylation of AKT1 protein HDAC6 mutant form inhibits the reaction [butylbenzyl phthalate results in increased phosphorylation of AKT1 protein] butylbenzyl phthalate affects the phosphorylation of AKT1 protein butylbenzyl phthalate results in decreased phosphorylation of AKT1 protein |
CTD |
PMID:22552774 PMID:29864457 PMID:31319113 PMID:33395283 |
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NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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G |
Akt2 |
AKT serine/threonine kinase 2 |
increases phosphorylation |
EXP |
butylbenzyl phthalate results in increased phosphorylation of AKT2 protein |
CTD |
PMID:31319113 |
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NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817
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G |
Aldh1a1 |
aldehyde dehydrogenase 1 family, member A1 |
multiple interactions |
ISO |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in increased expression of ALDH1A1 mRNA |
CTD |
PMID:30768133 |
|
NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
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G |
Aldoc |
aldolase, fructose-bisphosphate C |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of ALDOC mRNA |
CTD |
PMID:31199487 |
|
NCBI chr10:63,217,477...63,221,066
Ensembl chr10:63,217,451...63,221,066
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G |
Amh |
anti-Mullerian hormone |
multiple interactions increases expression |
EXP |
[butylbenzyl phthalate co-treated with 4-vinyl-1-cyclohexene dioxide] results in decreased expression of AMH mRNA; [butylbenzyl phthalate co-treated with Dibutyl Phthalate] results in decreased expression of AMH mRNA; butylbenzyl phthalate promotes the reaction [4-vinyl-1-cyclohexene dioxide results in decreased expression of AMH protein] butylbenzyl phthalate results in increased expression of AMH mRNA; butylbenzyl phthalate results in increased expression of AMH protein |
CTD |
PMID:29969652 PMID:31319113 |
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NCBI chr 7:8,906,776...8,909,192
Ensembl chr 7:8,906,836...8,909,282
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G |
Ar |
androgen receptor |
multiple interactions decreases activity affects activity affects binding |
ISO EXP |
butylbenzyl phthalate inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; butylbenzyl phthalate inhibits the reaction [Dihydrotestosterone binds to and results in increased activity of AR protein]; butylbenzyl phthalate inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]; butylbenzyl phthalate inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein] butylbenzyl phthalate results in decreased activity of AR protein butylbenzyl phthalate affects the activity of AR protein butylbenzyl phthalate binds to AR protein |
CTD |
PMID:9846162 PMID:14565775 PMID:15840436 PMID:18294747 PMID:20943248 PMID:28571686 PMID:29162470 PMID:33049310 More...
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NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925
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G |
Arnt |
aryl hydrocarbon receptor nuclear translocator |
multiple interactions increases expression |
ISO |
3',4'-dimethoxyflavone inhibits the reaction [butylbenzyl phthalate results in increased expression of ARNT mRNA]; 3',4'-dimethoxyflavone inhibits the reaction [butylbenzyl phthalate results in increased expression of ARNT protein]; AHR mutant form inhibits the reaction [butylbenzyl phthalate results in increased expression of ARNT mRNA]; AHR mutant form inhibits the reaction [butylbenzyl phthalate results in increased expression of ARNT protein]; butylbenzyl phthalate promotes the reaction [AHR protein binds to ARNT protein] butylbenzyl phthalate results in increased expression of ARNT mRNA; butylbenzyl phthalate results in increased expression of ARNT protein |
CTD |
PMID:22138065 |
|
NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580
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G |
Arnt2 |
aryl hydrocarbon receptor nuclear translocator 2 |
multiple interactions decreases expression |
ISO EXP |
1,3-bis(4-hydroxyphenyl)-4-methyl-5-(4-(2-piperidinylethoxy)phenol)-1H-pyrazole inhibits the reaction [butylbenzyl phthalate results in decreased expression of ARNT2 mRNA] [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of ARNT2 mRNA |
CTD |
PMID:21771643 PMID:31199487 |
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NCBI chr 1:138,236,235...138,392,868
Ensembl chr 1:138,189,940...138,393,153
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G |
Astn1 |
astrotactin 1 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of ASTN1 mRNA |
CTD |
PMID:31199487 |
|
NCBI chr13:70,537,423...70,855,440
Ensembl chr13:70,537,703...70,855,440
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G |
Astn2 |
astrotactin 2 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of ASTN2 mRNA |
CTD |
PMID:31199487 |
|
NCBI chr 5:78,758,142...79,744,021
Ensembl chr 5:78,758,142...79,748,273
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G |
Atm |
ATM serine/threonine kinase |
increases expression multiple interactions |
ISO |
butylbenzyl phthalate results in increased expression of ATM protein ATM protein affects the reaction [butylbenzyl phthalate results in increased expression of ZEB1 protein] |
CTD |
PMID:31212022 |
|
NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
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G |
Atp1a1 |
ATPase Na+/K+ transporting subunit alpha 1 |
increases expression |
EXP |
butylbenzyl phthalate results in increased expression of ATP1A1 mRNA |
CTD |
PMID:19560483 |
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NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837
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G |
Atp1a3 |
ATPase Na+/K+ transporting subunit alpha 3 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of ATP1A3 mRNA |
CTD |
PMID:31199487 |
|
NCBI chr 1:80,572,790...80,601,936
Ensembl chr 1:80,572,796...80,601,918
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G |
Bax |
BCL2 associated X, apoptosis regulator |
multiple interactions |
ISO |
[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with Diethylhexyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisononyl phthalate] results in increased expression of BAX mRNA; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of BAX mRNA |
CTD |
PMID:28013214 PMID:37021957 |
|
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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|
G |
Bcat1 |
branched chain amino acid transaminase 1 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of BCAT1 mRNA |
CTD |
PMID:31199487 |
|
NCBI chr 4:177,964,834...178,046,573
Ensembl chr 4:177,964,834...178,046,597
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G |
Bcl2 |
BCL2, apoptosis regulator |
multiple interactions decreases methylation increases expression |
ISO EXP |
[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with Diethylhexyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisononyl phthalate] results in increased expression of BCL2 mRNA; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in increased expression of BCL2 mRNA butylbenzyl phthalate results in decreased methylation of BCL2 promoter butylbenzyl phthalate results in increased expression of BCL2 mRNA |
CTD |
PMID:28013214 PMID:31016752 PMID:35487445 PMID:35762964 PMID:37021957 |
|
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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|
G |
Bcl2l10 |
Bcl2-like 10 |
multiple interactions |
ISO |
[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with Diethylhexyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisononyl phthalate] results in increased expression of BCL2L10 mRNA |
CTD |
PMID:37021957 |
|
NCBI chr 8:76,107,326...76,113,373
Ensembl chr 8:76,107,326...76,113,367
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|
G |
Bend6 |
BEN domain containing 6 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of BEND6 mRNA |
CTD |
PMID:31199487 |
|
NCBI chr 9:36,081,033...36,135,309
Ensembl chr 9:36,081,484...36,135,228
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|
G |
Bmp6 |
bone morphogenetic protein 6 |
decreases expression |
EXP |
butylbenzyl phthalate results in decreased expression of BMP6 mRNA |
CTD |
PMID:19560483 |
|
NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365
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|
G |
Bpgm |
bisphosphoglycerate mutase |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of BPGM mRNA |
CTD |
PMID:31199487 |
|
NCBI chr 4:63,139,730...63,168,581
Ensembl chr 4:63,140,018...63,168,581
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G |
Cacng7 |
calcium voltage-gated channel auxiliary subunit gamma 7 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CACNG7 mRNA |
CTD |
PMID:31199487 |
|
NCBI chr 1:65,800,059...65,831,246
Ensembl chr 1:65,800,355...65,831,006
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G |
Cadm3 |
cell adhesion molecule 3 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CADM3 mRNA |
CTD |
PMID:31199487 |
|
NCBI chr13:85,784,785...85,817,412
Ensembl chr13:85,786,483...85,817,749
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G |
Cadps |
calcium dependent secretion activator |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CADPS mRNA |
CTD |
PMID:31199487 |
|
NCBI chr15:12,289,803...12,742,786
Ensembl chr15:12,290,262...12,742,779
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G |
Camk4 |
calcium/calmodulin-dependent protein kinase IV |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CAMK4 mRNA |
CTD |
PMID:31199487 |
|
NCBI chr18:24,582,988...24,811,918
Ensembl chr18:24,585,269...24,802,487
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G |
Casp2 |
caspase 2 |
multiple interactions |
ISO |
[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with Diethylhexyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisononyl phthalate] results in increased expression of CASP2 mRNA |
CTD |
PMID:37021957 |
|
NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379
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G |
Casp3 |
caspase 3 |
increases expression multiple interactions |
ISO |
butylbenzyl phthalate results in increased expression of CASP3 protein alternative form [Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with 4-nonylphenol co-treated with 4-tert-octylphenol] results in increased expression of and results in increased activity of CASP3 protein; butylbenzyl phthalate results in increased expression of and results in increased activity of CASP3 protein |
CTD |
PMID:23220035 PMID:29029336 |
|
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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|
G |
Casp8 |
caspase 8 |
multiple interactions |
ISO |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CASP8 mRNA |
CTD |
PMID:28013214 |
|
NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
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G |
Cat |
catalase |
multiple interactions |
ISO |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CAT mRNA |
CTD |
PMID:28013214 |
|
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
multiple interactions |
ISO |
[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with Diethylhexyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisononyl phthalate] results in increased expression of CCL2 mRNA |
CTD |
PMID:37021957 |
|
NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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G |
Ccl5 |
C-C motif chemokine ligand 5 |
multiple interactions |
ISO |
[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with Diethylhexyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisononyl phthalate] results in increased expression of CCL5 mRNA |
CTD |
PMID:37021957 |
|
NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
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G |
Ccnd1 |
cyclin D1 |
multiple interactions decreases methylation increases expression |
ISO |
MIR19A mRNA affects the reaction [butylbenzyl phthalate results in increased expression of CCND1 protein]; MIR19B1 mRNA affects the reaction [butylbenzyl phthalate results in increased expression of CCND1 protein]; MIR34A mRNA inhibits the reaction [butylbenzyl phthalate results in increased expression of CCND1 protein] butylbenzyl phthalate results in decreased methylation of CCND1 promoter butylbenzyl phthalate results in increased expression of CCND1 mRNA; butylbenzyl phthalate results in increased expression of CCND1 protein |
CTD |
PMID:29864457 PMID:30243731 PMID:31016752 PMID:35487445 |
|
NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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G |
Ccnd2 |
cyclin D2 |
multiple interactions |
ISO |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CCND2 mRNA |
CTD |
PMID:28013214 |
|
NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
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G |
Cdh1 |
cadherin 1 |
decreases expression |
ISO |
butylbenzyl phthalate results in decreased expression of CDH1 protein |
CTD |
PMID:22552774 |
|
NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
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G |
Cdk4 |
cyclin-dependent kinase 4 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of CDK4 mRNA |
CTD |
PMID:35762964 |
|
NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403
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G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
decreases expression multiple interactions |
ISO EXP |
butylbenzyl phthalate results in decreased expression of CDKN1A mRNA; butylbenzyl phthalate results in decreased expression of CDKN1A protein [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CDKN1A mRNA [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] inhibits the reaction [CGA protein results in increased expression of CDKN1A mRNA] MIR19A mRNA affects the reaction [butylbenzyl phthalate results in decreased expression of CDKN1A protein]; MIR19B1 mRNA affects the reaction [butylbenzyl phthalate results in decreased expression of CDKN1A protein]; MIR34A mRNA inhibits the reaction [butylbenzyl phthalate results in decreased expression of CDKN1A protein] |
CTD |
PMID:29864457 PMID:30243731 PMID:33316053 PMID:35762964 |
|
NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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|
G |
Cdkn2a |
cyclin-dependent kinase inhibitor 2A |
multiple interactions increases methylation decreases expression |
ISO |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in increased expression of CDKN2A mRNA butylbenzyl phthalate results in increased methylation of CDKN2A promoter butylbenzyl phthalate results in decreased expression of CDKN2A mRNA |
CTD |
PMID:28013214 PMID:35487445 |
|
NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
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G |
Cebpa |
CCAAT/enhancer binding protein alpha |
multiple interactions |
ISO |
[1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased expression of CEBPA mRNA; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased expression of CEBPA protein; [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with Diethylhexyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisononyl phthalate] results in increased expression of CEBPA mRNA; butylbenzyl phthalate promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of CEBPA mRNA]; Curcumin inhibits the reaction [butylbenzyl phthalate promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of CEBPA mRNA]] |
CTD |
PMID:26820058 PMID:28595985 PMID:37021957 |
|
NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
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G |
Celsr3 |
cadherin, EGF LAG seven-pass G-type receptor 3 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CELSR3 mRNA |
CTD |
PMID:31199487 |
|
NCBI chr 8:109,530,597...109,558,360
Ensembl chr 8:109,530,641...109,558,354
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G |
Cfd |
complement factor D |
multiple interactions |
ISO |
[1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased expression of CFD mRNA |
CTD |
PMID:26820058 |
|
NCBI chr 7:9,813,148...9,814,871
Ensembl chr 7:9,813,150...9,815,053
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G |
Cga |
glycoprotein hormones, alpha polypeptide |
multiple interactions |
ISO |
butylbenzyl phthalate inhibits the reaction [CGA protein results in increased secretion of Dinoprostone]; butylbenzyl phthalate inhibits the reaction [CGA protein results in increased secretion of Progesterone] [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the reaction [CGA protein results in increased expression of ADAMTS1 mRNA]; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the reaction [CGA protein results in increased expression of EDN2 mRNA]; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the reaction [CGA protein results in increased expression of MMP9 mRNA]; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the reaction [CGA protein results in increased expression of PGR mRNA]; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the reaction [CGA protein results in increased expression of PLAT mRNA]; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] inhibits the reaction [CGA protein results in increased expression of ADAMTS1 mRNA]; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] inhibits the reaction [CGA protein results in increased expression of CDKN1A mRNA]; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] inhibits the reaction [CGA protein results in increased expression of IL6 mRNA]; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] inhibits the reaction [CGA protein results in increased expression of PTGS2 mRNA]; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] inhibits the reaction [CGA protein results in increased expression of SERPINB2 mRNA]; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] inhibits the reaction [CGA protein results in increased expression of SERPINE1 mRNA]; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] inhibits the reaction [CGA protein results in increased expression of TIMP1 mRNA]; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] inhibits the reaction [CGA protein results in increased expression of WNT4 mRNA]; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] promotes the reaction [CGA protein results in increased expression of MMP14 mRNA]; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] promotes the reaction [CGA protein results in increased expression of MMP16 mRNA]; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] promotes the reaction [CGA protein results in increased expression of SLCO2A1 mRNA] |
CTD |
PMID:25016925 PMID:33316053 |
|
NCBI chr 5:49,486,915...49,499,192
Ensembl chr 5:49,487,068...49,499,191
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G |
Chga |
chromogranin A |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CHGA mRNA |
CTD |
PMID:31199487 |
|
NCBI chr 6:121,696,051...121,707,399
Ensembl chr 6:121,696,051...121,707,398
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G |
Chgb |
chromogranin B |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CHGB mRNA |
CTD |
PMID:31199487 |
|
NCBI chr 3:120,043,824...120,057,169
Ensembl chr 3:120,043,738...120,057,166
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G |
Cited1 |
Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CITED1 mRNA |
CTD |
PMID:31199487 |
|
NCBI chr X:67,350,376...67,355,072
Ensembl chr X:67,350,373...67,355,162
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G |
Clstn3 |
calsyntenin 3 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CLSTN3 mRNA |
CTD |
PMID:31199487 |
|
NCBI chr 4:157,331,494...157,364,769
Ensembl chr 4:157,331,494...157,364,769
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G |
Cntnap1 |
contactin associated protein 1 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CNTNAP1 mRNA |
CTD |
PMID:31199487 |
|
NCBI chr10:86,109,850...86,125,612
Ensembl chr10:86,111,643...86,125,611
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G |
Comt |
catechol-O-methyltransferase |
decreases expression multiple interactions |
ISO |
butylbenzyl phthalate results in decreased expression of COMT mRNA fulvestrant inhibits the reaction [butylbenzyl phthalate results in decreased expression of COMT mRNA] |
CTD |
PMID:24040167 |
|
NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
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G |
Crh |
corticotropin releasing hormone |
multiple interactions |
ISO |
[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of CRH mRNA |
CTD |
PMID:32518293 |
|
NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919
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G |
Crhr1 |
corticotropin releasing hormone receptor 1 |
multiple interactions |
ISO |
[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of CRHR1 mRNA |
CTD |
PMID:32518293 |
|
NCBI chr10:89,040,186...89,083,481
Ensembl chr10:89,040,203...89,083,481
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G |
Crmp1 |
collapsin response mediator protein 1 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CRMP1 mRNA |
CTD |
PMID:31199487 |
|
NCBI chr14:73,509,933...73,556,192
Ensembl chr14:73,509,933...73,556,177
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|
G |
Ctnnb1 |
catenin beta 1 |
affects localization increases acetylation multiple interactions |
ISO |
butylbenzyl phthalate affects the localization of CTNNB1 protein butylbenzyl phthalate results in increased acetylation of CTNNB1 protein HDAC6 mutant form inhibits the reaction [butylbenzyl phthalate affects the localization of CTNNB1 protein]; trichostatin A inhibits the reaction [butylbenzyl phthalate affects the localization of CTNNB1 protein] |
CTD |
PMID:22552774 PMID:27923775 |
|
NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
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G |
Cyp11a1 |
cytochrome P450, family 11, subfamily a, polypeptide 1 |
increases expression multiple interactions |
EXP ISO |
butylbenzyl phthalate results in increased expression of CYP11A1 mRNA; butylbenzyl phthalate results in increased expression of CYP11A1 protein [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of CYP11A1 mRNA; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CYP11A1 mRNA; [Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with 4-nonylphenol co-treated with 4-tert-octylphenol] results in decreased expression of CYP11A1 mRNA; [Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diethyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate co-treated with diisononyl phthalate] results in decreased expression of CYP11A1 mRNA; [Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate] results in decreased expression of CYP11A1 mRNA |
CTD |
PMID:26472102 PMID:28013214 PMID:29029336 PMID:30802670 PMID:31319113 PMID:32518293 PMID:34597818 More...
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NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338
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G |
Cyp11b2 |
cytochrome P450, family 11, subfamily b, polypeptide 2 |
decreases expression |
EXP |
butylbenzyl phthalate results in decreased expression of CYP11B1 mRNA |
CTD |
PMID:33983380 |
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NCBI chr 7:106,838,590...106,845,004
Ensembl chr 7:106,838,590...106,845,004
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G |
Cyp11b3 |
cytochrome P450, family 11, subfamily b, polypeptide 3 |
decreases expression |
EXP |
butylbenzyl phthalate results in decreased expression of CYP11B2 mRNA |
CTD |
PMID:33983380 |
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NCBI chr 7:106,808,559...106,814,048
Ensembl chr 7:106,808,559...106,814,048
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G |
Cyp17a1 |
cytochrome P450, family 17, subfamily a, polypeptide 1 |
decreases expression multiple interactions |
EXP ISO |
butylbenzyl phthalate results in decreased expression of CYP17A1 mRNA [Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with 4-nonylphenol co-treated with 4-tert-octylphenol] results in increased expression of CYP17A1 mRNA; [Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diethyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate co-treated with diisononyl phthalate] results in decreased expression of CYP17A1 mRNA |
CTD |
PMID:26472102 PMID:29029336 PMID:30802670 PMID:33983380 |
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NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
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G |
Cyp19a1 |
cytochrome P450, family 19, subfamily a, polypeptide 1 |
multiple interactions decreases expression decreases activity |
ISO |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CYP19A1 mRNA; [Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with 4-nonylphenol co-treated with 4-tert-octylphenol] results in decreased expression of CYP19A1 mRNA; [Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with 4-nonylphenol co-treated with 4-tert-octylphenol] results in decreased expression of CYP19A1 protein; [Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate] results in decreased expression of CYP19A1 mRNA butylbenzyl phthalate results in increased expression of and results in increased activity of CYP19A1 protein; Fulvestrant inhibits the reaction [butylbenzyl phthalate results in increased activity of CYP19A1 protein] butylbenzyl phthalate results in decreased expression of CYP19A1 mRNA; butylbenzyl phthalate results in decreased expression of CYP19A1 protein butylbenzyl phthalate results in decreased activity of CYP19A1 protein |
CTD |
PMID:27825933 PMID:28013214 PMID:29029336 PMID:31016752 PMID:34597818 |
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NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758
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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
increases expression decreases activity |
ISO EXP |
butylbenzyl phthalate results in increased expression of CYP1A1 protein butylbenzyl phthalate results in decreased activity of CYP1A1 protein |
CTD |
PMID:22138065 PMID:27432241 |
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NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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G |
Cyp1a2 |
cytochrome P450, family 1, subfamily a, polypeptide 2 |
decreases activity |
EXP |
butylbenzyl phthalate results in decreased activity of CYP1A2 protein |
CTD |
PMID:27432241 |
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NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
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G |
Cyp1b1 |
cytochrome P450, family 1, subfamily b, polypeptide 1 |
multiple interactions increases expression |
ISO |
3',4'-dimethoxyflavone inhibits the reaction [butylbenzyl phthalate results in increased expression of CYP1B1 mRNA]; 3',4'-dimethoxyflavone inhibits the reaction [butylbenzyl phthalate results in increased expression of CYP1B1 protein]; AHR mutant form inhibits the reaction [butylbenzyl phthalate results in increased expression of CYP1B1 mRNA]; AHR mutant form inhibits the reaction [butylbenzyl phthalate results in increased expression of CYP1B1 protein]; butylbenzyl phthalate promotes the reaction [AHR protein binds to CYP1B1 promoter] butylbenzyl phthalate results in increased expression of CYP1B1 mRNA; butylbenzyl phthalate results in increased expression of CYP1B1 protein |
CTD |
PMID:22138065 |
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NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
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G |
Cyp27a1 |
cytochrome P450, family 27, subfamily a, polypeptide 1 |
increases expression |
EXP |
butylbenzyl phthalate results in increased expression of CYP27A1 mRNA |
CTD |
PMID:26472102 |
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NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551
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G |
Cyp2b1 |
cytochrome P450, family 2, subfamily b, polypeptide 1 |
increases expression decreases activity |
ISO EXP |
butylbenzyl phthalate results in increased expression of CYP2B10 mRNA butylbenzyl phthalate results in decreased activity of CYP2B1 protein |
CTD |
PMID:26519955 PMID:27432241 |
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NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
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G |
Cyp2c11 |
cytochrome P450, subfamily 2, polypeptide 11 |
decreases activity |
EXP |
butylbenzyl phthalate results in decreased activity of CYP2C11 protein |
CTD |
PMID:27432241 |
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NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066
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G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
decreases activity |
EXP |
butylbenzyl phthalate results in decreased activity of CYP2E1 protein |
CTD |
PMID:27432241 |
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NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
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G |
Cyp3a62 |
cytochrome P450, family 3, subfamily a, polypeptide 62 |
decreases activity |
EXP |
butylbenzyl phthalate results in decreased activity of CYP3A62 protein |
CTD |
PMID:27432241 |
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NCBI chr12:16,397,998...16,433,833
Ensembl chr12:16,397,998...16,433,833
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G |
Cyp51 |
cytochrome P450, family 51 |
decreases expression |
EXP |
butylbenzyl phthalate results in decreased expression of CYP51 mRNA |
CTD |
PMID:26472102 |
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NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410
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G |
Dclk3 |
doublecortin-like kinase 3 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of DCLK3 mRNA |
CTD |
PMID:31199487 |
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NCBI chr 8:111,401,544...111,453,999
Ensembl chr 8:111,401,358...111,453,999
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G |
Ddc |
dopa decarboxylase |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of DDC mRNA |
CTD |
PMID:31199487 |
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NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208
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G |
Dhcr7 |
7-dehydrocholesterol reductase |
decreases expression |
EXP |
butylbenzyl phthalate results in decreased expression of DHCR7 mRNA |
CTD |
PMID:33983380 |
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NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055
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G |
Dock3 |
dedicator of cyto-kinesis 3 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of DOCK3 mRNA |
CTD |
PMID:31199487 |
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NCBI chr 8:107,552,462...107,903,527
Ensembl chr 8:107,552,463...107,903,514
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G |
Dpf1 |
double PHD fingers 1 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of DPF1 mRNA |
CTD |
PMID:31199487 |
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NCBI chr 1:84,602,212...84,615,954
Ensembl chr 1:84,602,336...84,615,950
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G |
Dync1i1 |
dynein cytoplasmic 1 intermediate chain 1 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of DYNC1I1 mRNA |
CTD |
PMID:31199487 |
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NCBI chr 4:33,852,597...34,166,159
Ensembl chr 4:33,852,927...34,166,149
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G |
Ebp |
EBP, cholestenol delta-isomerase |
decreases expression |
EXP |
butylbenzyl phthalate results in decreased expression of EBP mRNA |
CTD |
PMID:26472102 |
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NCBI chr X:14,299,427...14,305,826
Ensembl chr X:14,299,448...14,305,826
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G |
Ece2 |
endothelin-converting enzyme 2 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of ECE2 mRNA |
CTD |
PMID:31199487 |
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NCBI chr11:80,259,130...80,278,446
Ensembl chr11:80,263,162...80,278,428
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G |
Edn1 |
endothelin 1 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of EDN1 mRNA |
CTD |
PMID:31199487 |
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NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
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G |
Edn2 |
endothelin 2 |
multiple interactions |
ISO |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the reaction [CGA protein results in increased expression of EDN2 mRNA] |
CTD |
PMID:33316053 |
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NCBI chr 5:133,751,316...133,756,814
Ensembl chr 5:133,751,217...133,756,814
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G |
Egfr |
epidermal growth factor receptor |
multiple interactions increases phosphorylation |
ISO |
fulvestrant inhibits the reaction [butylbenzyl phthalate results in increased phosphorylation of EGFR protein] |
CTD |
PMID:22552774 |
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NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
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G |
Elmod1 |
ELMO domain containing 1 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of ELMOD1 mRNA |
CTD |
PMID:31199487 |
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NCBI chr 8:54,298,363...54,355,348
Ensembl chr 8:54,298,363...54,355,140
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G |
Emx2 |
empty spiracles homeobox 2 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of EMX2 mRNA |
CTD |
PMID:31199487 |
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NCBI chr 1:258,626,584...258,633,594
Ensembl chr 1:258,626,584...258,633,594
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G |
Epdr1 |
ependymin related 1 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of EPDR1 mRNA |
CTD |
PMID:31199487 |
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NCBI chr17:45,333,932...45,358,597
Ensembl chr17:45,333,956...45,358,594
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G |
Espn |
espin |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of ESPN mRNA |
CTD |
PMID:31199487 |
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NCBI chr 5:162,626,560...162,660,439
Ensembl chr 5:162,626,560...162,660,256
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G |
Esr1 |
estrogen receptor 1 |
multiple interactions decreases expression increases activity affects binding decreases methylation |
ISO |
butylbenzyl phthalate binds to and results in increased activity of ESR1 protein; butylbenzyl phthalate inhibits the reaction [Estradiol results in increased activity of ESR1 protein]; Oxygen deficiency promotes the reaction [butylbenzyl phthalate results in decreased expression of ESR1 mRNA]; Oxygen deficiency promotes the reaction [butylbenzyl phthalate results in decreased expression of ESR1 protein]; Tamoxifen inhibits the reaction [butylbenzyl phthalate binds to and results in increased activity of ESR1 protein] butylbenzyl phthalate results in decreased expression of ESR1 mRNA; butylbenzyl phthalate results in decreased expression of ESR1 protein butylbenzyl phthalate results in increased activity of ESR1 protein [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of ESR1 mRNA butylbenzyl phthalate binds to ESR1 protein butylbenzyl phthalate results in decreased methylation of ESR1 gene; butylbenzyl phthalate results in decreased methylation of ESR1 promoter |
CTD |
PMID:15840436 PMID:16326419 PMID:19913605 PMID:20822795 PMID:22467034 PMID:22949852 PMID:28013214 PMID:28571686 PMID:29162470 PMID:30851587 PMID:33049310 More...
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NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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G |
Esr2 |
estrogen receptor 2 |
multiple interactions increases expression increases activity affects binding |
ISO |
butylbenzyl phthalate binds to and results in decreased activity of ESR2 protein; butylbenzyl phthalate binds to and results in increased activity of ESR2 protein; butylbenzyl phthalate inhibits the reaction [Estradiol results in increased activity of ESR2 protein] butylbenzyl phthalate results in increased expression of ESR2 mRNA [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of ESR2 mRNA butylbenzyl phthalate results in increased activity of ESR2 protein butylbenzyl phthalate binds to ESR2 protein |
CTD |
PMID:15840436 PMID:19913605 PMID:28571686 PMID:31016752 PMID:32518293 |
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NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
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G |
Fabp4 |
fatty acid binding protein 4 |
increases expression multiple interactions |
ISO |
butylbenzyl phthalate results in increased expression of FABP4 mRNA [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased expression of FABP4 mRNA |
CTD |
PMID:24155963 PMID:26820058 PMID:27923775 PMID:34520170 |
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NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578
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G |
Fabp5 |
fatty acid binding protein 5 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of FABP5 mRNA |
CTD |
PMID:31199487 |
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NCBI chr 2:91,765,056...91,768,716
Ensembl chr 2:91,765,056...91,853,773
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G |
Fam163a |
family with sequence similarity 163, member A |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of FAM163A mRNA |
CTD |
PMID:31199487 |
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NCBI chr13:68,262,867...68,341,323
Ensembl chr13:68,262,872...68,341,049
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G |
Fasn |
fatty acid synthase |
multiple interactions |
ISO |
[1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased expression of FASN mRNA; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased expression of FASN protein |
CTD |
PMID:26820058 |
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NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
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G |
Fez1 |
fasciculation and elongation protein zeta 1 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of FEZ1 mRNA |
CTD |
PMID:31199487 |
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NCBI chr 8:36,544,462...36,589,684
Ensembl chr 8:36,544,535...36,589,683
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G |
Fgf2 |
fibroblast growth factor 2 |
multiple interactions |
ISO |
[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with Diethylhexyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisononyl phthalate] results in increased expression of FGF2 mRNA |
CTD |
PMID:37021957 |
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NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
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G |
Fgfr2 |
fibroblast growth factor receptor 2 |
decreases expression |
EXP |
butylbenzyl phthalate results in decreased expression of FGFR2 mRNA |
CTD |
PMID:26472102 |
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NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626
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G |
Fkbp1b |
FKBP prolyl isomerase 1B |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of FKBP1B mRNA |
CTD |
PMID:31199487 |
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NCBI chr 6:27,832,128...27,850,600
Ensembl chr 6:27,838,802...27,848,653
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G |
Fkbp5 |
FKBP prolyl isomerase 5 |
multiple interactions |
ISO |
[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of FKBP5 mRNA |
CTD |
PMID:32518293 |
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NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674
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G |
Flg |
filaggrin |
multiple interactions |
ISO |
[FLG gene polymorphism affects the susceptibility to butylbenzyl phthalate] which affects the abundance of mono-benzyl phthalate |
CTD |
PMID:24380925 |
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NCBI chr 2:178,884,793...178,912,986
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G |
Foxo1 |
forkhead box O1 |
multiple interactions |
ISO |
butylbenzyl phthalate results in increased expression of and results in increased acetylation of FOXO1 protein |
CTD |
PMID:27923775 |
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NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
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G |
Fsd2 |
fibronectin type III and SPRY domain containing 2 |
increases expression decreases expression |
EXP |
butylbenzyl phthalate results in increased expression of FSD2 mRNA butylbenzyl phthalate results in decreased expression of FSD2 mRNA |
CTD |
PMID:26472102 |
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NCBI chr 1:135,484,002...135,522,517
Ensembl chr 1:135,489,266...135,522,472
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G |
Fshb |
follicle stimulating hormone subunit beta |
multiple interactions increases expression |
EXP ISO |
butylbenzyl phthalate promotes the reaction [Dibutyl Phthalate results in increased expression of FSHB protein] [Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate] results in decreased expression of FSHB protein butylbenzyl phthalate results in increased expression of FSHB protein |
CTD |
PMID:29969652 PMID:34597818 |
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NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370
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G |
Fshr |
follicle stimulating hormone receptor |
multiple interactions increases expression |
ISO EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of FSHR mRNA butylbenzyl phthalate results in increased expression of FSHR mRNA; butylbenzyl phthalate results in increased expression of FSHR protein |
CTD |
PMID:28013214 PMID:31319113 |
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NCBI chr 6:5,198,825...5,406,785
Ensembl chr 6:5,198,825...5,406,785
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G |
Fxyd7 |
FXYD domain-containing ion transport regulator 7 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of FXYD7 mRNA |
CTD |
PMID:31199487 |
|
NCBI chr 1:86,277,678...86,286,954
Ensembl chr 1:86,277,678...86,286,954
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|
G |
Gabpb1 |
GA binding protein transcription factor subunit beta 1 |
decreases expression |
ISO |
butylbenzyl phthalate results in decreased expression of GABPB1 mRNA |
CTD |
PMID:26520405 |
|
NCBI chr 3:113,879,972...113,924,742
Ensembl chr 3:113,879,973...113,923,696
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|
G |
Gfra3 |
GDNF family receptor alpha 3 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of GFRA3 mRNA |
CTD |
PMID:31199487 |
|
NCBI chr18:26,297,828...26,326,105
Ensembl chr18:26,297,829...26,326,105
|
|
G |
Gfra4 |
GDNF family receptor alpha 4 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of GFRA4 mRNA |
CTD |
PMID:31199487 |
|
NCBI chr 3:118,254,937...118,262,252
Ensembl chr 3:118,255,402...118,258,329
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G |
Ggta1 |
glycoprotein alpha-galactosyltransferase 1 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of GGTA1 mRNA |
CTD |
PMID:31199487 |
|
NCBI chr 3:18,732,985...18,824,916
Ensembl chr 3:18,732,991...18,809,908
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G |
Gng2 |
G protein subunit gamma 2 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of GNG2 mRNA |
CTD |
PMID:31199487 |
|
NCBI chr15:4,316,038...4,416,918
Ensembl chr15:4,316,059...4,417,183
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G |
Gpx1 |
glutathione peroxidase 1 |
multiple interactions |
ISO |
[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with Diethylhexyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisononyl phthalate] results in increased expression of GPX1 mRNA; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of GPX1 mRNA |
CTD |
PMID:28013214 PMID:37021957 |
|
NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
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G |
Grb14 |
growth factor receptor bound protein 14 |
increases expression |
EXP |
butylbenzyl phthalate results in increased expression of GRB14 mRNA |
CTD |
PMID:15728792 |
|
NCBI chr 3:49,568,210...49,683,805
Ensembl chr 3:49,568,210...49,683,889
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G |
Greb1 |
growth regulating estrogen receptor binding 1 |
increases expression |
ISO |
butylbenzyl phthalate results in increased expression of GREB1 mRNA |
CTD |
PMID:35307500 |
|
NCBI chr 6:39,440,522...39,562,364
Ensembl chr 6:39,440,504...39,581,633
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G |
Grin2b |
glutamate ionotropic receptor NMDA type subunit 2B |
multiple interactions |
ISO |
[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of GRIN2B mRNA |
CTD |
PMID:32518293 |
|
NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279
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G |
Gsk3b |
glycogen synthase kinase 3 beta |
multiple interactions increases phosphorylation |
ISO |
HDAC6 mutant form inhibits the reaction [butylbenzyl phthalate results in increased phosphorylation of GSK3B protein] |
CTD |
PMID:22552774 |
|
NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
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G |
Gsr |
glutathione-disulfide reductase |
multiple interactions |
ISO |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of GSR mRNA |
CTD |
PMID:28013214 |
|
NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
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G |
Gsta3 |
glutathione S-transferase alpha 3 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of GSTA3 mRNA |
CTD |
PMID:31199487 |
|
NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240
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|
G |
H19 |
H19 imprinted maternally expressed transcript |
decreases expression |
ISO |
butylbenzyl phthalate results in decreased expression of H19 mRNA |
CTD |
PMID:33395283 |
|
NCBI chr 1:197,730,698...197,733,374
Ensembl chr 1:197,730,698...197,733,134
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G |
Hdac6 |
histone deacetylase 6 |
multiple interactions increases response to substance increases expression |
ISO |
[butylbenzyl phthalate promotes the reaction [TFAP2A protein binds to HDAC6 promoter]] which results in increased expression of HDAC6 mRNA; butylbenzyl phthalate promotes the reaction [TFAP2A protein binds to HDAC6 promoter]; HDAC6 mutant form inhibits the reaction [butylbenzyl phthalate affects the localization of CTNNB1 protein]; HDAC6 mutant form inhibits the reaction [butylbenzyl phthalate promotes the reaction [[TCF4 protein binds to LEF1 protein] which binds to VIM protein]]; HDAC6 mutant form inhibits the reaction [butylbenzyl phthalate results in decreased expression of KRT7 protein]; HDAC6 mutant form inhibits the reaction [butylbenzyl phthalate results in increased expression of VIM protein]; HDAC6 mutant form inhibits the reaction [butylbenzyl phthalate results in increased phosphorylation of AKT1 protein]; HDAC6 mutant form inhibits the reaction [butylbenzyl phthalate results in increased phosphorylation of GSK3B protein]; TFAP2A mutant form inhibits the reaction [butylbenzyl phthalate results in increased expression of HDAC6 protein] HDAC6 results in increased susceptibility to butylbenzyl phthalate butylbenzyl phthalate results in increased expression of HDAC6 mRNA; butylbenzyl phthalate results in increased expression of HDAC6 protein |
CTD |
PMID:22552774 |
|
NCBI chr X:14,550,645...14,572,445
Ensembl chr X:14,551,044...14,572,441
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G |
Hey1 |
hes-related family bHLH transcription factor with YRPW motif 1 |
decreases expression |
EXP |
butylbenzyl phthalate results in decreased expression of HEY1 mRNA |
CTD |
PMID:26472102 |
|
NCBI chr 2:93,096,605...93,100,316
Ensembl chr 2:93,095,498...93,100,312
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G |
Hnf1a |
HNF1 homeobox A |
decreases expression |
EXP |
butylbenzyl phthalate results in decreased expression of HNF1A mRNA |
CTD |
PMID:15728792 |
|
NCBI chr12:41,638,536...41,672,806
Ensembl chr12:41,645,587...41,672,104
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G |
Hoxb8 |
homeo box B8 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of HOXB8 mRNA |
CTD |
PMID:31199487 |
|
NCBI chr10:81,248,313...81,251,261
Ensembl chr10:81,248,887...81,250,638
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G |
Hoxd3 |
homeo box D3 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of HOXD3 mRNA |
CTD |
PMID:31199487 |
|
NCBI chr 3:59,638,708...59,650,282
Ensembl chr 3:59,638,708...59,650,282
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G |
Hsd11b1 |
hydroxysteroid 11-beta dehydrogenase 1 |
increases expression |
EXP |
butylbenzyl phthalate results in increased expression of HSD11B1 protein |
CTD |
PMID:31319113 |
|
NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687
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G |
Hsd17b11 |
hydroxysteroid (17-beta) dehydrogenase 11 |
increases expression |
EXP |
butylbenzyl phthalate results in increased expression of HSD17B11 mRNA |
CTD |
PMID:26472102 |
|
NCBI chr14:5,693,304...5,743,157
Ensembl chr14:5,711,964...5,743,161
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G |
Hsd17b8 |
hydroxysteroid (17-beta) dehydrogenase 8 |
increases expression |
EXP |
butylbenzyl phthalate results in increased expression of HSD17B8 mRNA |
CTD |
PMID:19560483 PMID:26472102 |
|
NCBI chr20:4,826,725...4,828,742
Ensembl chr20:4,822,026...4,828,742
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G |
Hsd3b1 |
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 |
multiple interactions increases expression |
ISO EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of HSD3B1 mRNA [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in increased expression of HSD3B1 mRNA butylbenzyl phthalate results in increased expression of HSD3B1 mRNA; butylbenzyl phthalate results in increased expression of HSD3B1 protein |
CTD |
PMID:28013214 PMID:31319113 PMID:35762964 |
|
NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999
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G |
Hsd3b3 |
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3 |
decreases expression |
EXP |
butylbenzyl phthalate results in decreased expression of HSD3B3 mRNA |
CTD |
PMID:33983380 |
|
NCBI chr 2:186,138,044...186,144,024
Ensembl chr 2:186,138,044...186,144,033
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G |
Hspa12a |
heat shock protein family A (Hsp70) member 12A |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of HSPA12A mRNA |
CTD |
PMID:31199487 |
|
NCBI chr 1:257,935,642...258,096,602
Ensembl chr 1:257,935,644...258,096,846
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G |
Htr1a |
5-hydroxytryptamine receptor 1A |
multiple interactions |
ISO |
[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] affects the expression of HTR1A mRNA |
CTD |
PMID:32518293 |
|
NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442
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G |
Htr2a |
5-hydroxytryptamine receptor 2A |
multiple interactions |
ISO |
[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of HTR2A mRNA |
CTD |
PMID:32518293 |
|
NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928
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G |
Id1 |
inhibitor of DNA binding 1 |
decreases expression |
EXP |
butylbenzyl phthalate results in decreased expression of ID1 mRNA |
CTD |
PMID:26472102 |
|
NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419
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G |
Ido2 |
indoleamine 2,3-dioxygenase 2 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of IDO2 mRNA |
CTD |
PMID:31199487 |
|
NCBI chr16:67,459,158...67,498,052
Ensembl chr16:67,459,190...67,496,324
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G |
Igf1 |
insulin-like growth factor 1 |
decreases expression |
EXP |
butylbenzyl phthalate results in decreased expression of IGF1 mRNA |
CTD |
PMID:26472102 |
|
NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
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G |
Igfbp7 |
insulin-like growth factor binding protein 7 |
decreases expression |
EXP |
butylbenzyl phthalate results in decreased expression of IGFBP7 mRNA |
CTD |
PMID:19560483 |
|
NCBI chr14:30,737,414...30,797,317
Ensembl chr14:30,737,164...30,797,314
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G |
Il1b |
interleukin 1 beta |
multiple interactions |
ISO |
[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with Diethylhexyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisononyl phthalate] results in increased expression of IL1B mRNA |
CTD |
PMID:37021957 |
|
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il6 |
interleukin 6 |
multiple interactions |
ISO |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] inhibits the reaction [CGA protein results in increased expression of IL6 mRNA] |
CTD |
PMID:33316053 |
|
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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|
G |
Inha |
inhibin subunit alpha |
decreases expression |
EXP |
butylbenzyl phthalate results in decreased expression of INHA mRNA |
CTD |
PMID:26472102 PMID:33983380 |
|
NCBI chr 9:76,994,465...76,997,366
Ensembl chr 9:76,993,589...76,997,248
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G |
Ins1 |
insulin 1 |
multiple interactions |
ISO |
butylbenzyl phthalate promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ protein] |
CTD |
PMID:32407875 |
|
NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
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G |
Ins2 |
insulin 2 |
multiple interactions |
ISO |
[1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] affects the abundance of diphosphoric acid analog; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased abundance of carbamic acid analog; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased abundance of Cholesterol analog; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased abundance of Cystathionine analog; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased abundance of Desmosterol analog; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased abundance of ethylamine analog; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased abundance of Glycine analog; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased abundance of Inositol analog; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased abundance of methylphosphate analog; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased abundance of monoethyl phosphate analog; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased abundance of n-butylamine analog; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased abundance of Palmitic Acid analog; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased abundance of phosphoric acid analog; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased abundance of Pyrrolidonecarboxylic Acid analog; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased abundance of sebacic acid analog; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased abundance of stearic acid analog; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased abundance of undecane analog; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased expression of ACACA protein; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased expression of ADIPOQ mRNA; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased expression of ADIPOQ protein; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased expression of CEBPA mRNA; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased expression of CEBPA protein; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased expression of CFD mRNA; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased expression of FABP4 mRNA; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased expression of FASN mRNA; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased expression of FASN protein; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased expression of LPL mRNA; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased expression of PLIN1 protein; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased expression of PPARG mRNA; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased expression of PPARG protein; butylbenzyl phthalate promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased abundance of Triglycerides]; butylbenzyl phthalate promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of ADIPOQ mRNA]; butylbenzyl phthalate promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of CEBPA mRNA]; butylbenzyl phthalate promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of PPARG mRNA]; butylbenzyl phthalate promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of TNF mRNA]; Curcumin inhibits the reaction [butylbenzyl phthalate promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased abundance of Triglycerides]]; Curcumin inhibits the reaction [butylbenzyl phthalate promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of ADIPOQ mRNA]]; Curcumin inhibits the reaction [butylbenzyl phthalate promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of CEBPA mRNA]]; Curcumin inhibits the reaction [butylbenzyl phthalate promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of PPARG mRNA]]; Curcumin inhibits the reaction [butylbenzyl phthalate promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of TNF mRNA]] butylbenzyl phthalate promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in decreased secretion of TNFRSF11B protein]; butylbenzyl phthalate promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of and results in increased secretion of ADIPOQ protein]; butylbenzyl phthalate promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased secretion of ADIPOQ protein] |
CTD |
PMID:26820058 PMID:28595985 PMID:31016361 PMID:34864131 |
|
NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
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G |
Insig1 |
insulin induced gene 1 |
decreases expression |
EXP |
butylbenzyl phthalate results in decreased expression of INSIG1 mRNA |
CTD |
PMID:15728792 |
|
NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952
|
|
G |
Insl3 |
insulin-like 3 |
decreases expression |
EXP |
butylbenzyl phthalate results in decreased expression of INSL3 mRNA |
CTD |
PMID:14687758 PMID:16102138 PMID:18411233 PMID:33983380 |
|
NCBI chr16:18,398,682...18,400,566
Ensembl chr16:18,384,829...18,400,560
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|
G |
Irs1 |
insulin receptor substrate 1 |
decreases expression |
ISO |
butylbenzyl phthalate results in decreased expression of IRS1 mRNA |
CTD |
PMID:33395283 |
|
NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122
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|
G |
Kif5c |
kinesin family member 5C |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of KIF5C mRNA |
CTD |
PMID:31199487 |
|
NCBI chr 3:34,032,082...34,185,597
Ensembl chr 3:34,032,105...34,182,413
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|
G |
Krt7 |
keratin 7 |
decreases expression multiple interactions |
ISO |
butylbenzyl phthalate results in decreased expression of KRT7 protein HDAC6 mutant form inhibits the reaction [butylbenzyl phthalate results in decreased expression of KRT7 protein] |
CTD |
PMID:22552774 |
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NCBI chr 7:132,528,881...132,545,052
Ensembl chr 7:132,528,895...132,545,052
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G |
L1cam |
L1 cell adhesion molecule |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of L1CAM mRNA |
CTD |
PMID:31199487 |
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NCBI chr X:151,597,270...151,623,776
Ensembl chr X:151,597,277...151,623,857
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G |
Lamp3 |
lysosomal-associated membrane protein 3 |
decreases expression |
ISO |
butylbenzyl phthalate results in decreased expression of LAMP3 mRNA |
CTD |
PMID:20678512 |
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NCBI chr11:81,153,491...81,224,643
Ensembl chr11:81,193,649...81,221,784
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G |
Lcn2 |
lipocalin 2 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of LCN2 mRNA |
CTD |
PMID:31199487 |
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NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
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G |
Ldlr |
low density lipoprotein receptor |
decreases expression |
EXP |
butylbenzyl phthalate results in decreased expression of LDLR mRNA |
CTD |
PMID:15728792 |
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NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
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G |
Lef1 |
lymphoid enhancer binding factor 1 |
multiple interactions |
ISO |
butylbenzyl phthalate promotes the reaction [[TCF4 protein binds to LEF1 protein] which binds to VIM protein]; HDAC6 mutant form inhibits the reaction [butylbenzyl phthalate promotes the reaction [[TCF4 protein binds to LEF1 protein] which binds to VIM protein]]; trichostatin A inhibits the reaction [butylbenzyl phthalate promotes the reaction [[TCF4 protein binds to LEF1 protein] which binds to VIM protein]] |
CTD |
PMID:22552774 |
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NCBI chr 2:219,666,549...219,779,815
Ensembl chr 2:219,666,592...219,779,794
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G |
Lhcgr |
luteinizing hormone/choriogonadotropin receptor |
decreases expression increases expression |
EXP |
butylbenzyl phthalate results in decreased expression of LHCGR mRNA butylbenzyl phthalate results in increased expression of LHCGR mRNA; butylbenzyl phthalate results in increased expression of LHCGR protein |
CTD |
PMID:15728792 PMID:31319113 |
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NCBI chr 6:5,661,871...5,728,109
Ensembl chr 6:5,661,871...5,724,521
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G |
Lonrf2 |
LON peptidase N-terminal domain and ring finger 2 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of LONRF2 mRNA |
CTD |
PMID:31199487 |
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NCBI chr 9:41,033,125...41,070,551
Ensembl chr 9:41,034,628...41,070,649
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G |
Lpl |
lipoprotein lipase |
multiple interactions |
ISO |
[1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased expression of LPL mRNA; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in increased expression of LPL mRNA |
CTD |
PMID:26820058 PMID:30768133 |
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NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
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G |
Lrrc4b |
leucine rich repeat containing 4B |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of LRRC4B mRNA |
CTD |
PMID:31199487 |
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NCBI chr 1:94,922,034...94,956,309
Ensembl chr 1:94,935,603...94,956,263
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G |
Lynx1 |
Ly6/neurotoxin 1 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of LYNX1 mRNA |
CTD |
PMID:31199487 |
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NCBI chr 7:106,632,800...106,638,003
Ensembl chr 7:106,632,797...106,638,023
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G |
Map6 |
microtubule-associated protein 6 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of MAP6 mRNA |
CTD |
PMID:31199487 |
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NCBI chr 1:153,568,020...153,634,415
Ensembl chr 1:153,568,368...153,634,414
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G |
Mapk1 |
mitogen activated protein kinase 1 |
increases phosphorylation |
EXP |
butylbenzyl phthalate results in increased phosphorylation of MAPK1 protein |
CTD |
PMID:31319113 |
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NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk3 |
mitogen activated protein kinase 3 |
increases phosphorylation |
EXP |
butylbenzyl phthalate results in increased phosphorylation of MAPK3 protein |
CTD |
PMID:31319113 |
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NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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G |
Mapt |
microtubule-associated protein tau |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of MAPT mRNA |
CTD |
PMID:31199487 |
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NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
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G |
Mc2r |
melanocortin 2 receptor |
multiple interactions |
ISO |
[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of MC2R mRNA |
CTD |
PMID:32518293 |
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NCBI chr18:62,001,980...62,015,567
Ensembl chr18:62,004,948...62,015,488
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G |
Mir107 |
microRNA 107 |
increases expression |
ISO |
butylbenzyl phthalate results in increased expression of MIR107 mRNA |
CTD |
PMID:33395283 |
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NCBI chr 1:232,337,767...232,337,853
Ensembl chr 1:232,337,767...232,337,853
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G |
Mir141 |
microRNA 141 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in increased expression of MIR141 |
CTD |
PMID:31199487 |
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NCBI chr 4:157,523,239...157,523,332
Ensembl chr 4:157,523,239...157,523,332
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G |
Mir15b |
microRNA 15b |
decreases expression |
ISO |
butylbenzyl phthalate results in decreased expression of MIR15B mRNA |
CTD |
PMID:31629899 |
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NCBI chr 2:153,245,200...153,245,297
Ensembl chr 2:153,245,200...153,245,297
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G |
Mir184 |
microRNA 184 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in increased expression of MIR184; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in increased expression of MIR184 mRNA |
CTD |
PMID:31199487 PMID:35762964 |
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NCBI chr 8:90,343,134...90,343,210
Ensembl chr 8:90,343,134...90,343,210
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G |
Mir19a |
microRNA 19a |
multiple interactions increases expression |
ISO |
MIR19A mRNA affects the reaction [butylbenzyl phthalate results in decreased expression of CDKN1A protein]; MIR19A mRNA affects the reaction [butylbenzyl phthalate results in decreased expression of PTEN protein]; MIR19A mRNA affects the reaction [butylbenzyl phthalate results in increased expression of CCND1 protein]; MIR19A mRNA affects the reaction [butylbenzyl phthalate results in increased expression of PCNA protein] butylbenzyl phthalate results in increased expression of MIR19A mRNA |
CTD |
PMID:29864457 |
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NCBI chr15:92,180,912...92,180,993
Ensembl chr15:92,180,912...92,180,993
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G |
Mir19b1 |
microRNA 19b-1 |
multiple interactions increases expression |
ISO |
MIR19B1 mRNA affects the reaction [butylbenzyl phthalate results in decreased expression of CDKN1A protein]; MIR19B1 mRNA affects the reaction [butylbenzyl phthalate results in decreased expression of PTEN protein]; MIR19B1 mRNA affects the reaction [butylbenzyl phthalate results in increased expression of CCND1 protein]; MIR19B1 mRNA affects the reaction [butylbenzyl phthalate results in increased expression of PCNA protein] butylbenzyl phthalate results in increased expression of MIR19B1 mRNA |
CTD |
PMID:29864457 |
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NCBI chr15:92,181,214...92,181,300
Ensembl chr15:92,181,214...92,181,300
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G |
Mir34a |
microRNA 34a |
multiple interactions increases expression decreases expression |
ISO |
MIR34A mRNA inhibits the reaction [butylbenzyl phthalate results in decreased expression of CDKN1A protein]; MIR34A mRNA inhibits the reaction [butylbenzyl phthalate results in increased expression of CCND1 protein]; MIR34A mRNA inhibits the reaction [butylbenzyl phthalate results in increased expression of MYC protein]; MIR34A mRNA inhibits the reaction [butylbenzyl phthalate results in increased expression of PCNA protein] MIR34A mRNA affects the reaction [butylbenzyl phthalate results in decreased expression of NAMPT protein] butylbenzyl phthalate results in increased expression of MIR34A mRNA butylbenzyl phthalate results in decreased expression of MIR34A mRNA |
CTD |
PMID:30243731 PMID:34520170 |
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NCBI chr 5:160,533,002...160,533,103
Ensembl chr 5:160,533,002...160,533,103
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G |
Mirlet7a1 |
microRNA let-7a-1 |
increases expression |
ISO |
butylbenzyl phthalate results in increased expression of MIRLET7A-1 mRNA |
CTD |
PMID:33395283 |
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NCBI chr17:16,113,766...16,113,859
Ensembl chr17:16,113,768...16,113,867
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G |
Mirlet7b |
microRNA let-7b |
increases expression |
ISO |
butylbenzyl phthalate results in increased expression of MIRLET7B mRNA |
CTD |
PMID:33395283 |
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NCBI chr 7:116,804,186...116,804,270
Ensembl chr 7:116,804,186...116,804,270
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G |
Mirlet7c1 |
microRNA let-7c-1 |
increases expression |
ISO |
butylbenzyl phthalate results in increased expression of MIRLET7C-1 mRNA |
CTD |
PMID:33395283 |
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NCBI chr11:16,201,163...16,201,256
Ensembl chr11:16,201,158...16,201,265
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G |
Mirlet7d |
microRNA let-7d |
increases expression |
ISO |
butylbenzyl phthalate results in increased expression of MIRLET7D mRNA |
CTD |
PMID:33395283 |
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NCBI chr17:16,115,893...16,115,990
Ensembl chr17:16,115,893...16,115,990
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G |
Mirlet7f-1 |
microRNA let7f-1 |
increases expression |
ISO |
butylbenzyl phthalate results in increased expression of MIRLET7F-1 mRNA |
CTD |
PMID:33395283 |
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NCBI chr17:16,114,130...16,114,226
Ensembl chr17:16,114,130...16,114,226
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G |
Mllt11 |
MLLT11, transcription factor 7 cofactor |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of MLLT11 mRNA |
CTD |
PMID:31199487 |
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NCBI chr 2:182,795,790...182,804,960
Ensembl chr 2:182,795,790...182,797,199
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G |
Mmp14 |
matrix metallopeptidase 14 |
multiple interactions |
ISO |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] promotes the reaction [CGA protein results in increased expression of MMP14 mRNA] |
CTD |
PMID:33316053 |
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NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864
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G |
Mmp16 |
matrix metallopeptidase 16 |
multiple interactions |
ISO |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] promotes the reaction [CGA protein results in increased expression of MMP16 mRNA] |
CTD |
PMID:33316053 |
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NCBI chr 5:31,312,280...31,556,276
Ensembl chr 5:31,312,280...31,548,388
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G |
Mmp2 |
matrix metallopeptidase 2 |
multiple interactions increases expression |
ISO |
ZEB1 protein affects the reaction [butylbenzyl phthalate results in increased expression of MMP2 protein] |
CTD |
PMID:31212022 |
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NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
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G |
Mmp9 |
matrix metallopeptidase 9 |
increases expression multiple interactions |
ISO |
butylbenzyl phthalate results in increased expression of MMP9 protein [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the reaction [CGA protein results in increased expression of MMP9 mRNA] |
CTD |
PMID:31212022 PMID:33316053 |
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NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
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G |
Msh2 |
mutS homolog 2 |
decreases expression |
EXP |
butylbenzyl phthalate results in decreased expression of MSH2 mRNA |
CTD |
PMID:26472102 |
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NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938
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G |
Myc |
MYC proto-oncogene, bHLH transcription factor |
multiple interactions increases expression |
ISO |
MIR34A mRNA inhibits the reaction [butylbenzyl phthalate results in increased expression of MYC protein] butylbenzyl phthalate results in increased expression of MYC mRNA; butylbenzyl phthalate results in increased expression of MYC protein |
CTD |
PMID:30243731 |
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NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
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G |
Myocd |
myocardin |
decreases expression |
EXP |
butylbenzyl phthalate results in decreased expression of MYOCD mRNA |
CTD |
PMID:26472102 |
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NCBI chr10:49,833,219...49,928,806
Ensembl chr10:49,836,641...49,927,627
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G |
Nampt |
nicotinamide phosphoribosyltransferase |
decreases expression multiple interactions |
ISO |
butylbenzyl phthalate results in decreased expression of NAMPT mRNA; butylbenzyl phthalate results in decreased expression of NAMPT protein MIR34A mRNA affects the reaction [butylbenzyl phthalate results in decreased expression of NAMPT protein] |
CTD |
PMID:34520170 |
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NCBI chr 6:49,425,316...49,462,109
Ensembl chr 6:49,424,332...49,462,100
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G |
Ncs1 |
neuronal calcium sensor 1 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of NCS1 mRNA |
CTD |
PMID:31199487 |
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NCBI chr 3:14,523,220...14,568,829
Ensembl chr 3:14,523,220...14,568,829
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G |
Ndrg4 |
NDRG family member 4 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of NDRG4 mRNA |
CTD |
PMID:31199487 |
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NCBI chr19:9,351,408...9,387,398
Ensembl chr19:9,351,404...9,386,914
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G |
Nefh |
neurofilament heavy chain |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of NEFH mRNA |
CTD |
PMID:31199487 |
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NCBI chr14:79,830,362...79,840,347
Ensembl chr14:79,830,362...79,840,351
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G |
Nefl |
neurofilament light chain |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of NEFL mRNA |
CTD |
PMID:31199487 |
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NCBI chr15:42,301,920...42,305,793
Ensembl chr15:42,301,916...42,305,793
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G |
Nell1 |
neural EGFL like 1 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of NELL1 mRNA |
CTD |
PMID:31199487 |
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NCBI chr 1:99,709,305...100,573,872
Ensembl chr 1:99,709,793...100,573,860
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G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
decreases expression multiple interactions |
ISO |
butylbenzyl phthalate results in decreased expression of NFE2L2 mRNA [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with Diethylhexyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisononyl phthalate] results in increased expression of NFE2L2 mRNA |
CTD |
PMID:27923775 PMID:37021957 |
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NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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G |
Nfil3 |
nuclear factor, interleukin 3 regulated |
increases expression |
EXP |
butylbenzyl phthalate results in increased expression of NFIL3 mRNA |
CTD |
PMID:15728792 |
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NCBI chr17:12,280,499...12,295,728
Ensembl chr17:12,280,484...12,295,858
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G |
Ngfr |
nerve growth factor receptor |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of NGFR mRNA |
CTD |
PMID:31199487 |
|
NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518
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G |
Nr0b1 |
nuclear receptor subfamily 0, group B, member 1 |
decreases expression |
EXP |
butylbenzyl phthalate results in decreased expression of NR0B1 mRNA |
CTD |
PMID:15728792 PMID:33983380 |
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NCBI chr X:50,756,886...50,761,014
Ensembl chr X:50,756,886...50,761,011
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G |
Nr1i2 |
nuclear receptor subfamily 1, group I, member 2 |
increases activity multiple interactions |
ISO |
butylbenzyl phthalate results in increased activity of NR1I2 protein butylbenzyl phthalate binds to and results in increased activity of NR1I2 protein |
CTD |
PMID:27551952 PMID:33049310 |
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NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
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G |
Nr1i3 |
nuclear receptor subfamily 1, group I, member 3 |
affects binding increases activity |
ISO |
butylbenzyl phthalate binds to NR1I3 protein butylbenzyl phthalate results in increased activity of NR1I3 protein; butylbenzyl phthalate results in increased activity of NR1I3 protein alternative form |
CTD |
PMID:25938866 PMID:27551952 PMID:28927721 |
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NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
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G |
Nr3c1 |
nuclear receptor subfamily 3, group C, member 1 |
multiple interactions |
ISO |
[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] affects the expression of NR3C1 mRNA |
CTD |
PMID:32518293 |
|
NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
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G |
Nr3c2 |
nuclear receptor subfamily 3, group C, member 2 |
multiple interactions |
ISO |
[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of NR3C2 mRNA |
CTD |
PMID:32518293 |
|
NCBI chr19:30,715,634...31,059,885
Ensembl chr19:30,715,648...31,059,885
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G |
Nr4a3 |
nuclear receptor subfamily 4, group A, member 3 |
decreases expression |
EXP |
butylbenzyl phthalate results in decreased expression of NR4A3 mRNA |
CTD |
PMID:19560483 |
|
NCBI chr 5:62,361,588...62,401,489
Ensembl chr 5:62,361,822...62,402,733
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G |
Nrf1 |
nuclear respiratory factor 1 |
decreases expression |
ISO |
butylbenzyl phthalate results in decreased expression of NRF1 mRNA |
CTD |
PMID:26520405 PMID:27923775 |
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NCBI chr 4:58,664,932...58,772,328
Ensembl chr 4:58,664,957...58,825,328
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G |
Nrxn2 |
neurexin 2 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of NRXN2 mRNA |
CTD |
PMID:31199487 |
|
NCBI chr 1:203,726,420...203,842,301
Ensembl chr 1:203,735,753...203,842,297
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G |
Nsdhl |
NAD(P) dependent steroid dehydrogenase-like |
decreases expression |
EXP |
butylbenzyl phthalate results in decreased expression of NSDHL mRNA |
CTD |
PMID:19560483 |
|
NCBI chr X:150,775,034...150,807,161
Ensembl chr X:150,775,080...150,807,142
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G |
Nsg1 |
neuronal vesicle trafficking associated 1 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of NSG1 mRNA |
CTD |
PMID:31199487 |
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NCBI chr14:72,648,771...72,670,521
Ensembl chr14:72,648,741...72,670,514
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G |
Nsg2 |
neuronal vesicle trafficking associated 2 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of NSG2 mRNA |
CTD |
PMID:31199487 |
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NCBI chr10:15,601,594...15,661,441
Ensembl chr10:15,601,596...15,661,441
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G |
Olfm1 |
olfactomedin 1 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of OLFM1 mRNA |
CTD |
PMID:31199487 |
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NCBI chr 3:11,520,522...11,558,240
Ensembl chr 3:11,520,729...11,558,239
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G |
Oxt |
oxytocin/neurophysin I prepropeptide |
multiple interactions |
ISO |
[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of OXT mRNA |
CTD |
PMID:32518293 |
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NCBI chr 3:117,782,650...117,783,490
Ensembl chr 3:117,782,650...117,783,490
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G |
Oxtr |
oxytocin receptor |
multiple interactions |
ISO |
[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of OXTR mRNA |
CTD |
PMID:32518293 |
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NCBI chr 4:145,598,549...145,614,674
Ensembl chr 4:145,599,561...145,614,674
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G |
Pcna |
proliferating cell nuclear antigen |
multiple interactions increases expression |
ISO |
MIR19A mRNA affects the reaction [butylbenzyl phthalate results in increased expression of PCNA protein]; MIR19B1 mRNA affects the reaction [butylbenzyl phthalate results in increased expression of PCNA protein]; MIR34A mRNA inhibits the reaction [butylbenzyl phthalate results in increased expression of PCNA protein] butylbenzyl phthalate results in increased expression of PCNA mRNA; butylbenzyl phthalate results in increased expression of PCNA protein |
CTD |
PMID:29864457 PMID:30243731 PMID:31016752 |
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NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
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G |
Pcp4 |
Purkinje cell protein 4 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of PCP4 mRNA |
CTD |
PMID:31199487 |
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NCBI chr11:35,759,711...35,861,725
Ensembl chr11:35,800,713...35,861,725
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G |
Pdk4 |
pyruvate dehydrogenase kinase 4 |
increases expression multiple interactions |
ISO |
butylbenzyl phthalate results in increased expression of PDK4 protein butylbenzyl phthalate results in increased expression of and results in increased stability of PDK4 mRNA |
CTD |
PMID:31629899 |
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NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850
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G |
Pdp2 |
pyruvate dehydrogenase phosphatase catalytic subunit 2 |
increases expression |
ISO |
butylbenzyl phthalate results in increased expression of PDP2 mRNA |
CTD |
PMID:31629899 |
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NCBI chr19:386,408...394,068
Ensembl chr19:386,406...394,074
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G |
Pgr |
progesterone receptor |
increases expression multiple interactions |
EXP ISO |
butylbenzyl phthalate results in increased expression of PGR mRNA [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the reaction [CGA protein results in increased expression of PGR mRNA] |
CTD |
PMID:11474214 PMID:33316053 PMID:35307500 |
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NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344
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G |
Plat |
plasminogen activator, tissue type |
multiple interactions |
ISO |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the reaction [CGA protein results in increased expression of PLAT mRNA] |
CTD |
PMID:33316053 |
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NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223
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G |
Plin1 |
perilipin 1 |
multiple interactions increases expression |
ISO |
[1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased expression of PLIN1 protein; [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with Diethylhexyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisononyl phthalate] results in increased expression of PLIN1 mRNA butylbenzyl phthalate results in increased expression of PLIN1 protein |
CTD |
PMID:26820058 PMID:34520170 PMID:37021957 |
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NCBI chr 1:133,664,294...133,676,854
Ensembl chr 1:133,664,892...133,676,828
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G |
Plppr3 |
phospholipid phosphatase related 3 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of PLPPR3 mRNA |
CTD |
PMID:31199487 |
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NCBI chr 7:9,831,162...9,842,434
Ensembl chr 7:9,831,162...9,845,296
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G |
Pls1 |
plastin 1 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of PLS1 mRNA |
CTD |
PMID:31199487 |
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NCBI chr 8:96,316,703...96,426,592
Ensembl chr 8:96,317,849...96,385,195
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G |
Ppara |
peroxisome proliferator activated receptor alpha |
affects binding multiple interactions |
ISO |
butylbenzyl phthalate binds to PPARA protein [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of PPARA mRNA |
CTD |
PMID:23843199 PMID:28013214 |
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NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
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G |
Ppard |
peroxisome proliferator-activated receptor delta |
affects binding |
ISO |
butylbenzyl phthalate binds to PPARB protein |
CTD |
PMID:23843199 |
|
NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
affects binding increases activity increases expression multiple interactions |
ISO |
butylbenzyl phthalate binds to PPARG protein butylbenzyl phthalate results in increased activity of PPARG protein butylbenzyl phthalate results in increased expression of PPARG mRNA [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased expression of PPARG mRNA; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased expression of PPARG protein; butylbenzyl phthalate binds to and results in increased activity of PPARG protein; butylbenzyl phthalate promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of PPARG mRNA]; Curcumin inhibits the reaction [butylbenzyl phthalate promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of PPARG mRNA]]; PPARG protein promotes the reaction [butylbenzyl phthalate binds to and results in increased activity of PPARG protein] butylbenzyl phthalate binds to and results in increased activity of PPARG protein; butylbenzyl phthalate inhibits the reaction [GW 1929 binds to PPARG protein] |
CTD |
PMID:23843199 PMID:24155963 PMID:26172262 PMID:26820058 PMID:27923775 PMID:28595985 PMID:31016361 PMID:32407875 PMID:33049310 PMID:34520170 More...
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NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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G |
Ppargc1a |
PPARG coactivator 1 alpha |
decreases expression multiple interactions affects expression |
ISO |
butylbenzyl phthalate results in decreased expression of PPARGC1A mRNA [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with Diethylhexyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisononyl phthalate] results in decreased expression of PPARGC1A mRNA butylbenzyl phthalate affects the expression of PPARGC1A mRNA |
CTD |
PMID:26520405 PMID:27923775 PMID:37021957 |
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NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
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G |
Ppp2r2b |
protein phosphatase 2, regulatory subunit B, beta |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of PPP2R2B mRNA |
CTD |
PMID:31199487 |
|
NCBI chr18:34,653,716...35,080,889
Ensembl chr18:34,653,721...35,081,025
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G |
Prima1 |
proline rich membrane anchor 1 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of PRIMA1 mRNA |
CTD |
PMID:31199487 |
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NCBI chr 6:122,338,365...122,390,955
Ensembl chr 6:122,338,370...122,389,921
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G |
Prph |
peripherin |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of PRPH mRNA |
CTD |
PMID:31199487 |
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NCBI chr 7:130,218,149...130,222,136
Ensembl chr 7:130,218,357...130,222,136
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G |
Pten |
phosphatase and tensin homolog |
decreases expression multiple interactions |
ISO |
butylbenzyl phthalate results in decreased expression of PTEN mRNA; butylbenzyl phthalate results in decreased expression of PTEN protein MIR19A mRNA affects the reaction [butylbenzyl phthalate results in decreased expression of PTEN protein]; MIR19B1 mRNA affects the reaction [butylbenzyl phthalate results in decreased expression of PTEN protein] |
CTD |
PMID:29864457 |
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NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838
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G |
Ptges |
prostaglandin E synthase |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of PTGES mRNA |
CTD |
PMID:31199487 |
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NCBI chr 3:14,177,892...14,189,236
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G |
Ptgr1 |
prostaglandin reductase 1 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of PTGR1 mRNA |
CTD |
PMID:31199487 |
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NCBI chr 5:73,784,000...73,802,624
Ensembl chr 5:73,784,009...73,802,666
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions |
ISO |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] inhibits the reaction [CGA protein results in increased expression of PTGS2 mRNA] |
CTD |
PMID:33316053 |
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NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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G |
Ptprn |
protein tyrosine phosphatase, receptor type, N |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of PTPRN mRNA |
CTD |
PMID:31199487 |
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NCBI chr 9:76,741,010...76,756,704
Ensembl chr 9:76,741,016...76,756,190
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G |
Qsox1 |
quiescin sulfhydryl oxidase 1 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of QSOX1 mRNA |
CTD |
PMID:31199487 |
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NCBI chr13:67,949,780...67,987,434
Ensembl chr13:67,949,780...67,987,459
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G |
Rab3b |
RAB3B, member RAS oncogene family |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of RAB3B mRNA |
CTD |
PMID:31199487 |
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NCBI chr 5:123,629,562...123,697,410
Ensembl chr 5:123,644,423...123,697,401
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G |
Rab6b |
RAB6B, member RAS oncogene family |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of RAB6B mRNA |
CTD |
PMID:31199487 |
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NCBI chr 8:103,695,328...103,764,023
Ensembl chr 8:103,695,631...103,805,732
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G |
Rassf4 |
Ras association domain family member 4 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of RASSF4 mRNA |
CTD |
PMID:31199487 |
|
NCBI chr 4:149,897,525...149,932,658
Ensembl chr 4:149,897,543...149,932,411
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G |
Resp18 |
regulated endocrine-specific protein 18 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of RESP18 mRNA |
CTD |
PMID:31199487 |
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NCBI chr 9:76,765,179...76,771,824
Ensembl chr 9:76,764,590...76,778,722
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G |
Rnf183 |
ring finger protein 183 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in increased expression of RNF183 mRNA |
CTD |
PMID:31199487 |
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NCBI chr 5:75,877,111...75,886,253
Ensembl chr 5:75,876,003...75,886,191
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G |
Rtn1 |
reticulon 1 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of RTN1 mRNA |
CTD |
PMID:31199487 |
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NCBI chr 6:90,763,212...90,983,436
Ensembl chr 6:90,763,216...90,983,436
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G |
Rtn4r |
reticulon 4 receptor |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of RTN4R mRNA |
CTD |
PMID:31199487 |
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NCBI chr11:82,844,309...82,869,251
Ensembl chr11:82,844,309...82,869,466
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G |
Rxra |
retinoid X receptor alpha |
affects binding |
ISO |
butylbenzyl phthalate binds to RXRA protein |
CTD |
PMID:23843199 |
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NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
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G |
Rxrb |
retinoid X receptor beta |
affects binding |
ISO |
butylbenzyl phthalate binds to RXRB protein |
CTD |
PMID:23843199 |
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NCBI chr20:4,816,813...4,823,267
Ensembl chr20:4,816,815...4,828,773
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G |
Rxrg |
retinoid X receptor gamma |
affects binding |
ISO |
butylbenzyl phthalate binds to RXRG protein |
CTD |
PMID:23843199 |
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NCBI chr13:79,743,430...79,785,173
Ensembl chr13:79,743,563...79,785,167
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G |
Scarb1 |
scavenger receptor class B, member 1 |
decreases expression |
EXP |
butylbenzyl phthalate results in decreased expression of SCARB1 mRNA; butylbenzyl phthalate results in decreased expression of SCARB1 protein |
CTD |
PMID:26472102 PMID:31319113 PMID:33983380 |
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NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647
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G |
Scg3 |
secretogranin III |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of SCG3 mRNA |
CTD |
PMID:31199487 |
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NCBI chr 8:76,399,777...76,442,015
Ensembl chr 8:76,399,777...76,442,015
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G |
Scn3b |
sodium voltage-gated channel beta subunit 3 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of SCN3B mRNA |
CTD |
PMID:31199487 |
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NCBI chr 8:40,630,372...40,652,869
Ensembl chr 8:40,630,455...40,652,868
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G |
Scrn1 |
secernin 1 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of SCRN1 mRNA |
CTD |
PMID:31199487 |
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NCBI chr 4:83,632,125...83,694,225
Ensembl chr 4:83,632,131...83,693,852
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G |
Serpinb2 |
serpin family B member 2 |
multiple interactions |
ISO |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] inhibits the reaction [CGA protein results in increased expression of SERPINB2 mRNA] |
CTD |
PMID:33316053 |
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NCBI chr13:23,537,312...23,551,823
Ensembl chr13:23,541,400...23,550,408
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G |
Serpine1 |
serpin family E member 1 |
multiple interactions |
ISO |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] inhibits the reaction [CGA protein results in increased expression of SERPINE1 mRNA] |
CTD |
PMID:33316053 |
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NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
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G |
Sh3gl3 |
SH3 domain containing GRB2 like 3, endophilin A3 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of SH3GL3 mRNA |
CTD |
PMID:31199487 |
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NCBI chr 1:136,124,500...136,255,669
Ensembl chr 1:136,124,499...136,255,584
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G |
Sh3tc2 |
SH3 domain and tetratricopeptide repeats 2 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of SH3TC2 mRNA |
CTD |
PMID:31199487 |
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NCBI chr18:55,416,383...55,477,419
Ensembl chr18:55,416,413...55,483,083
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G |
Shbg |
sex hormone binding globulin |
affects binding |
ISO |
butylbenzyl phthalate binds to SHBG protein |
CTD |
PMID:25349334 |
|
NCBI chr10:54,332,939...54,350,409
Ensembl chr10:54,332,941...54,351,057
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G |
Shc2 |
SHC adaptor protein 2 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of SHC2 mRNA |
CTD |
PMID:31199487 |
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NCBI chr 7:10,066,705...10,088,926
Ensembl chr 7:10,066,705...10,088,926
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G |
Sirt1 |
sirtuin 1 |
decreases expression |
ISO |
butylbenzyl phthalate results in decreased expression of SIRT1 mRNA; butylbenzyl phthalate results in decreased expression of SIRT1 protein |
CTD |
PMID:26520405 PMID:27923775 PMID:34520170 |
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NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
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G |
Sirt3 |
sirtuin 3 |
decreases expression |
ISO |
butylbenzyl phthalate results in decreased expression of SIRT3 mRNA; butylbenzyl phthalate results in decreased expression of SIRT3 protein |
CTD |
PMID:26520405 PMID:27923775 PMID:34520170 |
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NCBI chr 1:195,942,066...195,964,472
Ensembl chr 1:195,942,073...195,964,808
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G |
Sirt7 |
sirtuin 7 |
decreases expression affects expression |
ISO |
butylbenzyl phthalate results in decreased expression of SIRT7 mRNA butylbenzyl phthalate affects the expression of SIRT7 mRNA |
CTD |
PMID:27923775 PMID:31016965 |
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NCBI chr10:105,896,476...105,903,301
Ensembl chr10:105,896,476...105,903,172
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G |
Slc13a2 |
solute carrier family 13 member 2 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of SLC13A2 mRNA |
CTD |
PMID:31199487 |
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NCBI chr10:63,291,813...63,319,127
Ensembl chr10:63,291,815...63,319,127
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G |
Slc29a4 |
solute carrier family 29 member 4 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of SLC29A4 mRNA |
CTD |
PMID:31199487 |
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NCBI chr12:11,853,540...11,884,660
Ensembl chr12:11,853,540...11,874,834
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G |
Slc5a5 |
solute carrier family 5 member 5 |
increases expression |
ISO EXP |
butylbenzyl phthalate results in increased expression of SLC5A5 mRNA |
CTD |
PMID:16257484 |
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NCBI chr16:18,546,709...18,556,698
Ensembl chr16:18,546,709...18,556,697
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G |
Slc5a7 |
solute carrier family 5 member 7 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of SLC5A7 mRNA |
CTD |
PMID:31199487 |
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NCBI chr 9:7,595,440...7,626,258
Ensembl chr 9:7,595,444...7,626,258
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G |
Slco2a1 |
solute carrier organic anion transporter family, member 2a1 |
multiple interactions |
ISO |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] promotes the reaction [CGA protein results in increased expression of SLCO2A1 mRNA] |
CTD |
PMID:33316053 |
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NCBI chr 8:103,588,916...103,672,546
Ensembl chr 8:103,588,916...103,672,546
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G |
Smim24 |
small integral membrane protein 24 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of SMIM24 mRNA |
CTD |
PMID:31199487 |
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NCBI chr 7:8,313,369...8,316,498
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G |
Snhg11 |
small nucleolar RNA host gene 11 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of SNHG11 mRNA |
CTD |
PMID:31199487 |
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NCBI chr 3:147,031,367...147,037,043
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G |
Sod1 |
superoxide dismutase 1 |
multiple interactions |
ISO |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of SOD1 mRNA |
CTD |
PMID:28013214 |
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NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
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G |
Sohlh2 |
spermatogenesis and oogenesis specific basic helix-loop-helix 2 |
increases expression decreases expression multiple interactions |
EXP |
butylbenzyl phthalate results in increased expression of SOHLH2 mRNA butylbenzyl phthalate results in decreased expression of SOHLH2 protein 4-vinyl-1-cyclohexene dioxide inhibits the reaction [butylbenzyl phthalate results in increased expression of SOHLH2 mRNA]; [4-vinyl-1-cyclohexene dioxide co-treated with butylbenzyl phthalate] results in decreased expression of SOHLH2 protein |
CTD |
PMID:29969652 |
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NCBI chr 2:139,362,246...139,384,700
Ensembl chr 2:139,362,246...139,384,699
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G |
Sox9 |
SRY-box transcription factor 9 |
decreases expression increases expression |
EXP |
butylbenzyl phthalate results in decreased expression of SOX9 mRNA butylbenzyl phthalate results in increased expression of SOX9 mRNA; butylbenzyl phthalate results in increased expression of SOX9 protein |
CTD |
PMID:26472102 PMID:31319113 |
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NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994
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G |
Sp1 |
Sp1 transcription factor |
decreases expression multiple interactions |
ISO |
butylbenzyl phthalate results in decreased expression of SP1 mRNA [Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with 4-nonylphenol co-treated with 4-tert-octylphenol] results in decreased expression of SP1 mRNA |
CTD |
PMID:29029336 |
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NCBI chr 7:133,541,302...133,571,961
Ensembl chr 7:133,541,491...133,571,961
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G |
Src |
SRC proto-oncogene, non-receptor tyrosine kinase |
multiple interactions increases phosphorylation |
ISO |
fulvestrant inhibits the reaction [butylbenzyl phthalate results in increased phosphorylation of SRC protein] |
CTD |
PMID:22552774 |
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NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
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G |
Srd5a1 |
steroid 5 alpha-reductase 1 |
decreases expression |
EXP |
butylbenzyl phthalate results in decreased expression of SRD5A1 mRNA |
CTD |
PMID:19560483 |
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NCBI chr 1:33,686,069...33,720,468
Ensembl chr 1:33,686,391...33,720,461
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G |
Star |
steroidogenic acute regulatory protein |
decreases expression multiple interactions increases expression |
EXP ISO |
butylbenzyl phthalate results in decreased expression of STAR mRNA; butylbenzyl phthalate results in decreased expression of STAR protein [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in increased expression of STAR mRNA [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of STAR mRNA; [Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with 4-nonylphenol co-treated with 4-tert-octylphenol] results in increased expression of STAR mRNA; [Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diethyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate co-treated with diisononyl phthalate] results in decreased expression of STAR mRNA; [Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate] results in decreased expression of STAR mRNA butylbenzyl phthalate results in increased expression of STAR mRNA |
CTD |
PMID:19560483 PMID:26472102 PMID:28013214 PMID:29029336 PMID:30802670 PMID:31319113 PMID:33983380 PMID:34597818 PMID:35762964 More...
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NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
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G |
Stk32c |
serine/threonine kinase 32C |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of STK32C mRNA |
CTD |
PMID:31199487 |
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NCBI chr 1:193,900,718...193,981,723
Ensembl chr 1:193,900,718...193,981,723
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G |
Stmn4 |
stathmin 4 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of STMN4 mRNA |
CTD |
PMID:31199487 |
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NCBI chr15:40,541,305...40,559,253
Ensembl chr15:40,541,357...40,559,253
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G |
Syt11 |
synaptotagmin 11 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of SYT11 mRNA |
CTD |
PMID:31199487 |
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NCBI chr 2:174,206,032...174,232,540
Ensembl chr 2:174,206,191...174,231,964
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G |
Syt5 |
synaptotagmin 5 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of SYT5 mRNA |
CTD |
PMID:31199487 |
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NCBI chr 1:69,277,351...69,285,071
Ensembl chr 1:69,277,351...69,285,067
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G |
Tbx2 |
T-box transcription factor 2 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of TBX2 mRNA |
CTD |
PMID:31199487 |
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NCBI chr10:70,679,670...70,688,868
Ensembl chr10:70,679,518...70,688,529
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G |
Tcf21 |
transcription factor 21 |
increases expression decreases expression |
EXP |
butylbenzyl phthalate results in increased expression of TCF21 mRNA butylbenzyl phthalate results in decreased expression of TCF21 mRNA |
CTD |
PMID:26472102 |
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NCBI chr 1:22,701,353...22,704,212
Ensembl chr 1:22,701,353...22,704,202
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G |
Tcf23 |
transcription factor 23 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of TCF23 mRNA |
CTD |
PMID:31199487 |
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NCBI chr 6:25,397,889...25,406,639
Ensembl chr 6:25,397,937...25,405,880
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G |
Tcf4 |
transcription factor 4 |
multiple interactions |
ISO |
butylbenzyl phthalate promotes the reaction [[TCF4 protein binds to LEF1 protein] which binds to VIM protein]; HDAC6 mutant form inhibits the reaction [butylbenzyl phthalate promotes the reaction [[TCF4 protein binds to LEF1 protein] which binds to VIM protein]]; trichostatin A inhibits the reaction [butylbenzyl phthalate promotes the reaction [[TCF4 protein binds to LEF1 protein] which binds to VIM protein]] |
CTD |
PMID:22552774 |
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NCBI chr18:62,941,739...63,288,126
Ensembl chr18:62,943,782...63,284,425
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G |
Tcte1 |
t-complex-associated testis expressed 1 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of TCTE1 mRNA |
CTD |
PMID:31199487 |
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NCBI chr 9:15,463,573...15,482,258
Ensembl chr 9:15,463,739...15,472,954
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G |
Tfam |
transcription factor A, mitochondrial |
decreases expression |
ISO |
butylbenzyl phthalate results in decreased expression of TFAM mRNA |
CTD |
PMID:27923775 |
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NCBI chr20:17,356,243...17,368,293
Ensembl chr20:17,356,197...17,368,292
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G |
Tfap2a |
transcription factor AP-2 alpha |
affects localization multiple interactions |
ISO |
butylbenzyl phthalate affects the localization of TFAP2A protein [butylbenzyl phthalate promotes the reaction [TFAP2A protein binds to HDAC6 promoter]] which results in increased expression of HDAC6 mRNA; butylbenzyl phthalate promotes the reaction [TFAP2A protein binds to HDAC6 promoter]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [butylbenzyl phthalate affects the localization of TFAP2A protein]; RTKI cpd inhibits the reaction [butylbenzyl phthalate affects the localization of TFAP2A protein]; TFAP2A mutant form inhibits the reaction [butylbenzyl phthalate results in increased expression of HDAC6 protein] |
CTD |
PMID:22552774 |
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NCBI chr17:24,028,716...24,047,507
Ensembl chr17:24,024,432...24,047,507
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G |
Tff1 |
trefoil factor 1 |
increases expression |
ISO |
butylbenzyl phthalate results in increased expression of TFF1 mRNA |
CTD |
PMID:35307500 |
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NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597
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G |
Thy1 |
Thy-1 cell surface antigen |
increases expression |
ISO |
butylbenzyl phthalate results in increased expression of THY1 protein |
CTD |
PMID:22552774 |
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NCBI chr 8:44,389,495...44,394,688
Ensembl chr 8:44,389,513...44,394,659
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G |
Timp1 |
TIMP metallopeptidase inhibitor 1 |
multiple interactions |
ISO |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] inhibits the reaction [CGA protein results in increased expression of TIMP1 mRNA] |
CTD |
PMID:33316053 |
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NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664
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G |
Tmeff2 |
transmembrane protein with EGF-like and two follistatin-like domains 2 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of TMEFF2 mRNA |
CTD |
PMID:31199487 |
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NCBI chr 9:50,445,947...50,733,473
Ensembl chr 9:50,436,079...50,733,475
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G |
Tmem130 |
transmembrane protein 130 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of TMEM130 mRNA |
CTD |
PMID:31199487 |
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NCBI chr12:9,837,055...9,862,843
Ensembl chr12:9,837,055...9,862,840
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G |
Tmem35a |
transmembrane protein 35A |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of TMEM35A mRNA |
CTD |
PMID:31199487 |
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NCBI chr X:97,503,350...97,514,198
Ensembl chr X:97,503,350...97,514,197
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G |
Tmem63c |
transmembrane protein 63c |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of TMEM63C mRNA |
CTD |
PMID:31199487 |
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NCBI chr 6:106,667,389...106,738,778
Ensembl chr 6:106,672,934...106,736,990
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G |
Tnf |
tumor necrosis factor |
multiple interactions |
ISO |
butylbenzyl phthalate inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; butylbenzyl phthalate promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of TNF mRNA]; Curcumin inhibits the reaction [butylbenzyl phthalate promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of TNF mRNA]] |
CTD |
PMID:15256756 PMID:28595985 |
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Tnfrsf11b |
TNF receptor superfamily member 11B |
multiple interactions |
ISO |
butylbenzyl phthalate promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in decreased secretion of TNFRSF11B protein] |
CTD |
PMID:31016361 |
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NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538
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G |
Tp53 |
tumor protein p53 |
increases methylation decreases expression |
ISO |
butylbenzyl phthalate results in increased methylation of TP53 promoter butylbenzyl phthalate results in decreased expression of TP53 mRNA |
CTD |
PMID:31016752 PMID:35487445 |
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NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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G |
Trpc6 |
transient receptor potential cation channel, subfamily C, member 6 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of TRPC6 mRNA |
CTD |
PMID:31199487 |
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NCBI chr 8:5,759,387...5,864,000
Ensembl chr 8:5,758,935...5,828,092
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G |
Ttyh1 |
tweety family member 1 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of TTYH1 mRNA |
CTD |
PMID:31199487 |
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NCBI chr 1:70,053,312...70,071,872
Ensembl chr 1:70,053,324...70,071,845
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G |
Tubb2b |
tubulin, beta 2B class IIb |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of TUBB2B mRNA |
CTD |
PMID:31199487 |
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NCBI chr17:30,747,734...30,750,781
Ensembl chr17:30,747,734...30,750,638
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G |
Tubb3 |
tubulin, beta 3 class III |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of TUBB3 mRNA |
CTD |
PMID:31199487 |
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NCBI chr19:51,457,187...51,466,243
Ensembl chr19:51,457,184...51,466,243
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G |
Tubb4a |
tubulin, beta 4A class IVa |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of TUBB4A mRNA |
CTD |
PMID:31199487 |
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NCBI chr 9:1,917,841...1,925,286
Ensembl chr 9:1,917,845...1,925,291
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G |
Ubash3b |
ubiquitin associated and SH3 domain containing, B |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of UBASH3B mRNA |
CTD |
PMID:31199487 |
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NCBI chr 8:41,385,419...41,532,248
Ensembl chr 8:41,388,341...41,532,201
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G |
Ubxn11 |
UBX domain protein 11 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of UBXN11 mRNA |
CTD |
PMID:31199487 |
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NCBI chr 5:146,329,666...146,353,529
Ensembl chr 5:146,329,842...146,353,526
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G |
Ucp1 |
uncoupling protein 1 |
multiple interactions |
ISO |
[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with Diethylhexyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisononyl phthalate] results in decreased expression of UCP1 mRNA |
CTD |
PMID:37021957 |
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NCBI chr19:24,808,782...24,816,853
Ensembl chr19:24,808,783...24,816,852
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G |
Vegfa |
vascular endothelial growth factor A |
multiple interactions decreases secretion increases secretion |
ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [butylbenzyl phthalate results in increased secretion of VEGFA protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [butylbenzyl phthalate results in increased secretion of VEGFA protein]; butylbenzyl phthalate promotes the reaction [Oxygen deficiency results in increased secretion of VEGFA protein]; SB 203580 inhibits the reaction [butylbenzyl phthalate results in increased secretion of VEGFA protein]; Wortmannin inhibits the reaction [butylbenzyl phthalate results in increased secretion of VEGFA protein] butylbenzyl phthalate results in decreased secretion of VEGFA protein |
CTD |
PMID:18252963 PMID:25016925 PMID:30851587 |
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NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
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G |
Vim |
vimentin |
multiple interactions increases expression |
ISO |
butylbenzyl phthalate promotes the reaction [[TCF4 protein binds to LEF1 protein] which binds to VIM protein]; HDAC6 mutant form inhibits the reaction [butylbenzyl phthalate promotes the reaction [[TCF4 protein binds to LEF1 protein] which binds to VIM protein]]; HDAC6 mutant form inhibits the reaction [butylbenzyl phthalate results in increased expression of VIM protein]; trichostatin A inhibits the reaction [butylbenzyl phthalate promotes the reaction [[TCF4 protein binds to LEF1 protein] which binds to VIM protein]] |
CTD |
PMID:22552774 PMID:31212022 |
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NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
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G |
Wnt4 |
Wnt family member 4 |
multiple interactions |
ISO |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] inhibits the reaction [CGA protein results in increased expression of WNT4 mRNA] |
CTD |
PMID:33316053 |
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NCBI chr 5:149,513,573...149,535,415
Ensembl chr 5:149,514,018...149,532,859
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G |
Wnt6 |
Wnt family member 6 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of WNT6 mRNA |
CTD |
PMID:31199487 |
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NCBI chr 9:76,329,882...76,343,523
Ensembl chr 9:76,329,882...76,343,523
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G |
Wnt9b |
Wnt family member 9B |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of WNT9B mRNA |
CTD |
PMID:31199487 |
|
NCBI chr10:88,635,330...88,657,035
Ensembl chr10:88,635,331...88,657,035
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G |
Wt1 |
WT1 transcription factor |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of WT1 mRNA |
CTD |
PMID:31199487 |
|
NCBI chr 3:91,566,540...91,613,653
Ensembl chr 3:91,567,001...91,613,643
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G |
Zcchc12 |
zinc finger CCHC-type containing 12 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of ZCCHC12 mRNA |
CTD |
PMID:31199487 |
|
NCBI chr X:115,433,444...115,436,691
Ensembl chr X:115,433,259...115,436,692
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G |
Zeb1 |
zinc finger E-box binding homeobox 1 |
multiple interactions increases expression increases stability |
ISO |
butylbenzyl phthalate results in increased expression of and results in increased stability of ZEB1 mRNA; MIR655 mRNA inhibits the reaction [butylbenzyl phthalate results in increased expression of ZEB1 mRNA]; ZEB1 protein affects the reaction [butylbenzyl phthalate results in increased expression of MMP2 protein] butylbenzyl phthalate results in increased expression of ZEB1 protein ATM protein affects the reaction [butylbenzyl phthalate results in increased expression of ZEB1 protein]; butylbenzyl phthalate results in increased expression of and affects the localization of ZEB1 protein; butylbenzyl phthalate results in increased expression of and results in increased stability of ZEB1 mRNA; MIR655 mRNA inhibits the reaction [butylbenzyl phthalate results in increased expression of ZEB1 protein]; ZEB1 protein affects the reaction [butylbenzyl phthalate results in increased expression of MMP2 protein] butylbenzyl phthalate results in increased stability of ZEB1 protein |
CTD |
PMID:31212022 |
|
NCBI chr17:51,948,948...52,116,018
Ensembl chr17:51,948,948...52,115,214
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G |
Zfat |
zinc finger and AT hook domain containing |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in increased expression of ZFAT mRNA |
CTD |
PMID:31199487 |
|
NCBI chr 7:99,886,954...100,054,288
Ensembl chr 7:99,886,954...100,054,274
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G |
Zp2 |
zona pellucida glycoprotein 2 |
multiple interactions |
EXP |
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of ZP2 mRNA |
CTD |
PMID:31199487 |
|
NCBI chr 1:174,513,507...174,525,288
Ensembl chr 1:174,513,511...174,525,288
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G |
Agt |
angiotensinogen |
multiple interactions |
ISO |
CGP 42112A inhibits the reaction [[AGT protein co-treated with Rotenone] results in increased expression of CYBB mRNA]; CGP 42112A inhibits the reaction [[AGT protein co-treated with Rotenone] results in increased expression of CYBB protein]; CGP 42112A inhibits the reaction [[AGT protein co-treated with Rotenone] results in increased expression of NOX1 mRNA]; CGP 42112A inhibits the reaction [[AGT protein co-treated with Rotenone] results in increased expression of NOX1 protein]; CGP 42112A inhibits the reaction [[AGT protein co-treated with Rotenone] results in increased expression of NOX4 mRNA]; CGP 42112A inhibits the reaction [[AGT protein co-treated with Rotenone] results in increased expression of NOX4 protein]; CGP 42112A inhibits the reaction [AGT protein promotes the reaction [Rotenone results in increased expression of AGTRAP mRNA]]; CGP 42112A inhibits the reaction [AGT protein promotes the reaction [Rotenone results in increased expression of AGTRAP protein]]; CGP 42112A promotes the reaction [[AGT protein co-treated with Rotenone] results in increased expression of AGTR2 protein]; CGP 42112A promotes the reaction [AGT protein promotes the reaction [Rotenone results in increased expression of AGTR2 mRNA]]; PD 123319 inhibits the reaction [CGP 42112A inhibits the reaction [[AGT protein co-treated with Rotenone] results in increased expression of CYBB mRNA]]; PD 123319 inhibits the reaction [CGP 42112A inhibits the reaction [[AGT protein co-treated with Rotenone] results in increased expression of CYBB protein]]; PD 123319 inhibits the reaction [CGP 42112A inhibits the reaction [[AGT protein co-treated with Rotenone] results in increased expression of NOX1 mRNA]]; PD 123319 inhibits the reaction [CGP 42112A inhibits the reaction [[AGT protein co-treated with Rotenone] results in increased expression of NOX1 protein]]; PD 123319 inhibits the reaction [CGP 42112A inhibits the reaction [[AGT protein co-treated with Rotenone] results in increased expression of NOX4 mRNA]]; PD 123319 inhibits the reaction [CGP 42112A inhibits the reaction [AGT protein promotes the reaction [Rotenone results in increased expression of AGTRAP mRNA]]]; PD 123319 inhibits the reaction [CGP 42112A inhibits the reaction [AGT protein promotes the reaction [Rotenone results in increased expression of AGTRAP protein]]]; PD 123319 inhibits the reaction [CGP 42112A promotes the reaction [[AGT protein co-treated with Rotenone] results in increased expression of AGTR2 protein]]; PD 123319 inhibits the reaction [CGP 42112A promotes the reaction [AGT protein promotes the reaction [Rotenone results in increased expression of AGTR2 mRNA]]] |
CTD |
PMID:25446015 |
|
NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
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G |
Agtr2 |
angiotensin II receptor, type 2 |
multiple interactions |
ISO EXP |
CGP 42112A promotes the reaction [[AGT protein co-treated with Rotenone] results in increased expression of AGTR2 protein]; CGP 42112A promotes the reaction [AGT protein promotes the reaction [Rotenone results in increased expression of AGTR2 mRNA]]; PD 123319 inhibits the reaction [CGP 42112A promotes the reaction [[AGT protein co-treated with Rotenone] results in increased expression of AGTR2 protein]]; PD 123319 inhibits the reaction [CGP 42112A promotes the reaction [AGT protein promotes the reaction [Rotenone results in increased expression of AGTR2 mRNA]]] [CGP 42112A binds to and results in increased activity of AGTR2 protein] which affects the susceptibility to Phenylephrine; [CGP 42112A binds to and results in increased activity of AGTR2 protein] which results in increased abundance of and results in increased secretion of Triglycerides; [CGP 42112A binds to and results in increased activity of AGTR2 protein] which results in increased abundance of Fatty Acids, Nonesterified; CGP 42112A binds to and results in increased activity of AGTR2 protein |
CTD |
PMID:16003179 PMID:19151255 PMID:25446015 |
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NCBI chr X:112,119,876...112,124,060
Ensembl chr X:112,120,228...112,124,057
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G |
Agtrap |
angiotensin II receptor-associated protein |
multiple interactions |
ISO |
CGP 42112A inhibits the reaction [AGT protein promotes the reaction [Rotenone results in increased expression of AGTRAP mRNA]]; CGP 42112A inhibits the reaction [AGT protein promotes the reaction [Rotenone results in increased expression of AGTRAP protein]]; PD 123319 inhibits the reaction [CGP 42112A inhibits the reaction [AGT protein promotes the reaction [Rotenone results in increased expression of AGTRAP mRNA]]]; PD 123319 inhibits the reaction [CGP 42112A inhibits the reaction [AGT protein promotes the reaction [Rotenone results in increased expression of AGTRAP protein]]] |
CTD |
PMID:25446015 |
|
NCBI chr 5:158,507,427...158,519,036
Ensembl chr 5:158,508,749...158,519,036
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G |
Cybb |
cytochrome b-245 beta chain |
multiple interactions |
ISO |
CGP 42112A inhibits the reaction [[AGT protein co-treated with Rotenone] results in increased expression of CYBB mRNA]; CGP 42112A inhibits the reaction [[AGT protein co-treated with Rotenone] results in increased expression of CYBB protein]; PD 123319 inhibits the reaction [CGP 42112A inhibits the reaction [[AGT protein co-treated with Rotenone] results in increased expression of CYBB mRNA]]; PD 123319 inhibits the reaction [CGP 42112A inhibits the reaction [[AGT protein co-treated with Rotenone] results in increased expression of CYBB protein]] |
CTD |
PMID:25446015 |
|
NCBI chr X:13,358,101...13,392,570
Ensembl chr X:13,359,430...13,392,586
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G |
Nox1 |
NADPH oxidase 1 |
multiple interactions |
ISO |
CGP 42112A inhibits the reaction [[AGT protein co-treated with Rotenone] results in increased expression of NOX1 mRNA]; CGP 42112A inhibits the reaction [[AGT protein co-treated with Rotenone] results in increased expression of NOX1 protein]; PD 123319 inhibits the reaction [CGP 42112A inhibits the reaction [[AGT protein co-treated with Rotenone] results in increased expression of NOX1 mRNA]]; PD 123319 inhibits the reaction [CGP 42112A inhibits the reaction [[AGT protein co-treated with Rotenone] results in increased expression of NOX1 protein]] |
CTD |
PMID:25446015 |
|
NCBI chr X:97,279,058...97,332,291
Ensembl chr X:97,279,056...97,302,236
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G |
Nox4 |
NADPH oxidase 4 |
multiple interactions |
ISO |
CGP 42112A inhibits the reaction [[AGT protein co-treated with Rotenone] results in increased expression of NOX4 mRNA]; CGP 42112A inhibits the reaction [[AGT protein co-treated with Rotenone] results in increased expression of NOX4 protein]; PD 123319 inhibits the reaction [CGP 42112A inhibits the reaction [[AGT protein co-treated with Rotenone] results in increased expression of NOX4 mRNA]] |
CTD |
PMID:25446015 |
|
NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406
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G |
Ube2v2 |
ubiquitin conjugating enzyme E2 V2 |
increases expression |
EXP |
CGP 42112A results in increased expression of UBE2V2 mRNA; CGP 42112A results in increased expression of UBE2V2 protein |
CTD |
PMID:17068200 |
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NCBI chr11:85,304,528...85,338,430
Ensembl chr11:85,304,526...85,336,369
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G |
Ache |
acetylcholinesterase |
multiple interactions decreases activity |
ISO |
[crotoxyphos co-treated with Dichlorvos] results in decreased activity of ACHE protein crotoxyphos results in decreased activity of ACHE protein |
CTD |
PMID:4859365 |
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NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
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G |
Ahr |
aryl hydrocarbon receptor |
affects expression multiple interactions |
ISO |
mono-benzyl phthalate affects the expression of AHR mRNA [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] affects the expression of AHR mRNA |
CTD |
PMID:28381288 PMID:31884101 |
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NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
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G |
Ahrr |
aryl-hydrocarbon receptor repressor |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] affects the expression of AHRR mRNA |
CTD |
PMID:31884101 |
|
NCBI chr 1:28,993,634...29,088,673
Ensembl chr 1:28,993,634...29,088,673
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G |
Aifm1 |
apoptosis inducing factor, mitochondria associated 1 |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of AIFM1 mRNA |
CTD |
PMID:31884101 |
|
NCBI chr X:127,650,223...127,689,356
Ensembl chr X:127,650,226...127,689,256
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G |
Ar |
androgen receptor |
multiple interactions |
ISO |
mono-benzyl phthalate promotes the reaction [Dihydrotestosterone results in increased activity of AR protein] [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of AR mRNA |
CTD |
PMID:28571686 PMID:31884101 |
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NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925
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G |
Arnt |
aryl hydrocarbon receptor nuclear translocator |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] affects the expression of ARNT mRNA |
CTD |
PMID:31884101 |
|
NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580
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G |
Bax |
BCL2 associated X, apoptosis regulator |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of BAX mRNA [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of BAX mRNA |
CTD |
PMID:31884101 PMID:35861251 |
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NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Bcl2 |
BCL2, apoptosis regulator |
multiple interactions decreases methylation increases expression |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] affects the expression of BCL2 mRNA [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of BCL2 mRNA mono-benzyl phthalate results in decreased methylation of BCL2 promoter mono-benzyl phthalate results in increased expression of BCL2 mRNA |
CTD |
PMID:31884101 PMID:35487445 PMID:35861251 |
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NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Bcl2l10 |
Bcl2-like 10 |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of BCL2L10 mRNA |
CTD |
PMID:31884101 |
|
NCBI chr 8:76,107,326...76,113,373
Ensembl chr 8:76,107,326...76,113,367
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G |
Bid |
BH3 interacting domain death agonist |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of BID mRNA |
CTD |
PMID:31884101 |
|
NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
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G |
Bok |
BCL2 family apoptosis regulator BOK |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of BOK mRNA |
CTD |
PMID:31884101 |
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NCBI chr 9:94,223,493...94,234,476
Ensembl chr 9:94,223,389...94,234,476
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G |
Casp3 |
caspase 3 |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CASP3 mRNA [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] affects the expression of CASP3 mRNA |
CTD |
PMID:31884101 PMID:35861251 |
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Casp8 |
caspase 8 |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CASP8 mRNA [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of CASP8 mRNA |
CTD |
PMID:31884101 PMID:35861251 |
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NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
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G |
Cat |
catalase |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of CAT mRNA [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of CAT mRNA |
CTD |
PMID:31884101 PMID:35861251 |
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NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
increases expression |
ISO |
mono-benzyl phthalate results in increased expression of CCL2 mRNA |
CTD |
PMID:32015430 |
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NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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G |
Ccna2 |
cyclin A2 |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CCNA2 mRNA |
CTD |
PMID:31884101 |
|
NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
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G |
Ccnb1 |
cyclin B1 |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CCNB1 mRNA |
CTD |
PMID:31884101 |
|
NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
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G |
Ccnb2 |
cyclin B2 |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CCNB2 mRNA |
CTD |
PMID:31884101 |
|
NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874
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G |
Ccnd1 |
cyclin D1 |
increases expression decreases methylation |
ISO |
mono-benzyl phthalate results in increased expression of CCND1 mRNA mono-benzyl phthalate results in decreased methylation of CCND1 promoter |
CTD |
PMID:35487445 |
|
NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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G |
Ccnd3 |
cyclin D3 |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CCND3 mRNA |
CTD |
PMID:31884101 |
|
NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371
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G |
Ccne1 |
cyclin E1 |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CCNE1 mRNA |
CTD |
PMID:31884101 |
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NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
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G |
Ccr7 |
C-C motif chemokine receptor 7 |
multiple interactions |
ISO |
[bisphenol A co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-benzyl phthalate co-treated with monobutyl phthalate] results in increased expression of CCR7 mRNA |
CTD |
PMID:30398665 |
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NCBI chr10:84,098,193...84,108,309
Ensembl chr10:84,097,381...84,108,309
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G |
Cd163 |
CD163 molecule |
multiple interactions |
ISO |
[bisphenol A co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-benzyl phthalate co-treated with monobutyl phthalate] results in decreased expression of CD163 mRNA |
CTD |
PMID:30398665 |
|
NCBI chr 4:157,085,080...157,118,470
Ensembl chr 4:157,085,093...157,117,878
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G |
Cd36 |
CD36 molecule |
increases expression multiple interactions |
ISO |
mono-benzyl phthalate results in increased expression of CD36 mRNA GW 6471 inhibits the reaction [mono-benzyl phthalate results in increased expression of CD36 mRNA] |
CTD |
PMID:35421560 |
|
NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
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G |
Cd68 |
Cd68 molecule |
increases expression |
ISO |
mono-benzyl phthalate results in increased expression of CD68 mRNA |
CTD |
PMID:32015430 |
|
NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697
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G |
Cdk2 |
cyclin dependent kinase 2 |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CDK2 mRNA |
CTD |
PMID:31884101 |
|
NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
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G |
Cdk4 |
cyclin-dependent kinase 4 |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CDK4 mRNA |
CTD |
PMID:31884101 |
|
NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403
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G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of CDKN1A mRNA |
CTD |
PMID:31884101 |
|
NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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G |
Cdkn1b |
cyclin-dependent kinase inhibitor 1B |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CDKN1B mRNA |
CTD |
PMID:31884101 |
|
NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
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G |
Cdkn1c |
cyclin-dependent kinase inhibitor 1C |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CDKN1C mRNA |
CTD |
PMID:31884101 |
|
NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048
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G |
Cdkn2a |
cyclin-dependent kinase inhibitor 2A |
multiple interactions increases methylation decreases expression |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of CDKN2A mRNA [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CDKN2A mRNA mono-benzyl phthalate results in increased methylation of CDKN2A promoter mono-benzyl phthalate results in decreased expression of CDKN2A mRNA |
CTD |
PMID:31884101 PMID:35487445 PMID:35861251 |
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NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
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G |
Cdkn2b |
cyclin-dependent kinase inhibitor 2B |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of CDKN2B mRNA |
CTD |
PMID:31884101 |
|
NCBI chr 5:104,009,839...104,019,082
Ensembl chr 5:104,010,680...104,019,050
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G |
Cdkn2c |
cyclin-dependent kinase inhibitor 2C |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CDKN2C mRNA |
CTD |
PMID:31884101 |
|
NCBI chr 5:124,411,123...124,416,278
Ensembl chr 5:124,411,124...124,416,278
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G |
Cdkn2d |
cyclin dependent kinase inhibitor 2D |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] affects the expression of CDKN2D mRNA |
CTD |
PMID:31884101 |
|
NCBI chr 8:19,831,874...19,834,640
Ensembl chr 8:19,831,866...19,834,674
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G |
Cga |
glycoprotein hormones, alpha polypeptide |
increases expression affects expression increases secretion |
ISO |
mono-benzyl phthalate results in increased expression of CGA mRNA mono-benzyl phthalate affects the expression of CGA mRNA mono-benzyl phthalate results in increased secretion of CGA protein |
CTD |
PMID:28381288 PMID:29089286 |
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NCBI chr 5:49,486,915...49,499,192
Ensembl chr 5:49,487,068...49,499,191
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G |
Crp |
C-reactive protein |
increases expression |
ISO |
mono-benzyl phthalate results in increased expression of CRP protein |
CTD |
PMID:21349512 |
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NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178
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G |
Cxcl10 |
C-X-C motif chemokine ligand 10 |
multiple interactions |
ISO |
[bisphenol A co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-benzyl phthalate co-treated with monobutyl phthalate] results in increased expression of CXCL10 mRNA |
CTD |
PMID:30398665 |
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NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
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G |
Cyp11a1 |
cytochrome P450, family 11, subfamily a, polypeptide 1 |
increases expression multiple interactions affects expression |
ISO |
mono-benzyl phthalate results in increased expression of CYP11A1 mRNA [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CYP11A1 mRNA mono-benzyl phthalate affects the expression of CYP11A1 mRNA |
CTD |
PMID:28381288 PMID:29089286 PMID:31884101 |
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NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338
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G |
Cyp17a1 |
cytochrome P450, family 17, subfamily a, polypeptide 1 |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CYP17A1 mRNA |
CTD |
PMID:31884101 |
|
NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
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G |
Cyp19a1 |
cytochrome P450, family 19, subfamily a, polypeptide 1 |
affects expression multiple interactions |
ISO |
mono-benzyl phthalate affects the expression of CYP19A1 mRNA [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CYP19A1 mRNA |
CTD |
PMID:28381288 PMID:31884101 |
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NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758
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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of CYP1A1 mRNA |
CTD |
PMID:31884101 |
|
NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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G |
Cyp1b1 |
cytochrome P450, family 1, subfamily b, polypeptide 1 |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CYP1B1 mRNA |
CTD |
PMID:31884101 |
|
NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
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G |
Cyp2b1 |
cytochrome P450, family 2, subfamily b, polypeptide 1 |
decreases activity |
EXP |
mono-benzyl phthalate results in decreased activity of CYP2B1 protein |
CTD |
PMID:27432241 |
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NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
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G |
Cyp3a62 |
cytochrome P450, family 3, subfamily a, polypeptide 62 |
decreases activity |
EXP |
mono-benzyl phthalate results in decreased activity of CYP3A62 protein |
CTD |
PMID:27432241 |
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NCBI chr12:16,397,998...16,433,833
Ensembl chr12:16,397,998...16,433,833
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G |
Dicer1 |
dicer 1 ribonuclease III |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of DICER1 mRNA |
CTD |
PMID:35861251 |
|
NCBI chr 6:123,627,529...123,692,278
Ensembl chr 6:123,631,250...123,693,965
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G |
Dnmt1 |
DNA methyltransferase 1 |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] affects the expression of DNMT1 mRNA; [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of DNMT1 mRNA |
CTD |
PMID:35861251 |
|
NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
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G |
Drosha |
drosha ribonuclease III |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of DROSHA mRNA |
CTD |
PMID:35861251 |
|
NCBI chr 2:61,864,886...61,976,688
Ensembl chr 2:61,864,970...61,976,688
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G |
Ereg |
epiregulin |
increases expression |
ISO |
mono-benzyl phthalate results in increased expression of EREG mRNA |
CTD |
PMID:29089286 |
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NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062
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G |
Esr1 |
estrogen receptor 1 |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] affects the expression of ESR1 mRNA; mono-benzyl phthalate promotes the reaction [Estradiol results in increased activity of ESR1 protein] [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of ESR1 mRNA |
CTD |
PMID:28571686 PMID:31884101 PMID:35861251 |
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NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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G |
Esr2 |
estrogen receptor 2 |
multiple interactions |
ISO |
mono-benzyl phthalate promotes the reaction [Estradiol results in increased activity of ESR2 protein] [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of ESR2 mRNA |
CTD |
PMID:28571686 PMID:31884101 |
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NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
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G |
Fabp4 |
fatty acid binding protein 4 |
multiple interactions increases expression |
ISO |
T 0070907 inhibits the reaction [mono-benzyl phthalate results in increased expression of FABP4 mRNA] |
CTD |
PMID:35421560 |
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NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578
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G |
Flg |
filaggrin |
multiple interactions |
ISO |
[FLG gene polymorphism affects the susceptibility to butylbenzyl phthalate] which affects the abundance of mono-benzyl phthalate |
CTD |
PMID:24380925 |
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NCBI chr 2:178,884,793...178,912,986
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G |
Fshr |
follicle stimulating hormone receptor |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of FSHR mRNA |
CTD |
PMID:31884101 |
|
NCBI chr 6:5,198,825...5,406,785
Ensembl chr 6:5,198,825...5,406,785
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G |
Gpx1 |
glutathione peroxidase 1 |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of GPX1 mRNA |
CTD |
PMID:31884101 |
|
NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
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G |
Gsr |
glutathione-disulfide reductase |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of GSR mRNA |
CTD |
PMID:31884101 |
|
NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
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G |
Hsd17b1 |
hydroxysteroid (17-beta) dehydrogenase 1 |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of HSD17B1 mRNA |
CTD |
PMID:31884101 |
|
NCBI chr10:86,009,728...86,011,928
Ensembl chr10:86,009,728...86,011,927
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G |
Hsd3b1 |
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of HSD3B1 mRNA |
CTD |
PMID:31884101 |
|
NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999
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G |
Il6 |
interleukin 6 |
multiple interactions |
ISO |
[bisphenol A co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-benzyl phthalate co-treated with monobutyl phthalate] results in increased expression of IL6 mRNA |
CTD |
PMID:30398665 |
|
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Lhcgr |
luteinizing hormone/choriogonadotropin receptor |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of LHCGR mRNA |
CTD |
PMID:31884101 |
|
NCBI chr 6:5,661,871...5,728,109
Ensembl chr 6:5,661,871...5,724,521
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G |
Mir141 |
microRNA 141 |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of MIR141 mRNA |
CTD |
PMID:35861251 |
|
NCBI chr 4:157,523,239...157,523,332
Ensembl chr 4:157,523,239...157,523,332
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G |
Mir184 |
microRNA 184 |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] affects the expression of MIR184 mRNA |
CTD |
PMID:35861251 |
|
NCBI chr 8:90,343,134...90,343,210
Ensembl chr 8:90,343,134...90,343,210
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G |
Mki67 |
marker of proliferation Ki-67 |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of MKI67 mRNA [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] affects the expression of MKI67 mRNA |
CTD |
PMID:31884101 PMID:35861251 |
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NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
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G |
Mmp9 |
matrix metallopeptidase 9 |
multiple interactions |
ISO |
[bisphenol A co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-benzyl phthalate co-treated with monobutyl phthalate] results in increased secretion of MMP9 protein |
CTD |
PMID:30398665 |
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NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
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G |
Mrc1 |
mannose receptor, C type 1 |
multiple interactions |
ISO |
[bisphenol A co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-benzyl phthalate co-treated with monobutyl phthalate] results in decreased expression of MRC1 mRNA |
CTD |
PMID:30398665 |
|
NCBI chr17:77,249,187...77,330,857
Ensembl chr17:77,249,187...77,330,857
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G |
Nr1i2 |
nuclear receptor subfamily 1, group I, member 2 |
increases activity |
ISO |
mono-benzyl phthalate results in increased activity of NR1I2 protein |
CTD |
PMID:27551952 |
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NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
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G |
Nr1i3 |
nuclear receptor subfamily 1, group I, member 3 |
increases activity multiple interactions |
ISO |
mono-benzyl phthalate results in increased activity of NR1I3 protein alternative form [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of NR1I3 mRNA |
CTD |
PMID:27551952 PMID:31884101 |
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NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
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G |
Ppara |
peroxisome proliferator activated receptor alpha |
affects binding multiple interactions increases activity |
ISO |
mono-benzyl phthalate binds to PPARA protein [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of PPARA mRNA mono-benzyl phthalate results in increased activity of PPARA protein |
CTD |
PMID:23843199 PMID:27551952 PMID:31884101 |
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NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
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G |
Ppard |
peroxisome proliferator-activated receptor delta |
affects binding multiple interactions increases activity |
ISO |
mono-benzyl phthalate binds to PPARB protein [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of PPARD mRNA mono-benzyl phthalate results in increased activity of PPARD protein |
CTD |
PMID:23843199 PMID:27551952 PMID:31884101 |
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NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
affects binding multiple interactions increases expression increases activity |
ISO |
mono-benzyl phthalate binds to PPARG protein [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of PPARG mRNA mono-benzyl phthalate results in increased expression of PPARG protein mono-benzyl phthalate results in increased activity of PPARG protein |
CTD |
PMID:23843199 PMID:27551952 PMID:29089286 PMID:31884101 |
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NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
affects expression |
ISO |
mono-benzyl phthalate affects the expression of PTGS2 mRNA |
CTD |
PMID:29089286 |
|
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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G |
Shbg |
sex hormone binding globulin |
multiple interactions decreases secretion |
ISO |
[Phthalic Acids results in increased abundance of mono-benzyl phthalate] which results in increased expression of and results in increased secretion of SHBG protein mono-benzyl phthalate results in decreased secretion of SHBG protein |
CTD |
PMID:24945889 PMID:28637469 |
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NCBI chr10:54,332,939...54,350,409
Ensembl chr10:54,332,941...54,351,057
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G |
Skp2 |
S-phase kinase associated protein 2 |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of SKP2 mRNA |
CTD |
PMID:31884101 |
|
NCBI chr 2:58,161,226...58,189,293
Ensembl chr 2:58,161,229...58,189,338
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G |
Sod1 |
superoxide dismutase 1 |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of SOD1 mRNA |
CTD |
PMID:35861251 |
|
NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
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G |
Star |
steroidogenic acute regulatory protein |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of STAR mRNA |
CTD |
PMID:31884101 |
|
NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
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G |
Tnf |
tumor necrosis factor |
increases expression |
ISO |
mono-benzyl phthalate results in increased expression of TNF mRNA |
CTD |
PMID:32015430 |
|
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Tp53 |
tumor protein p53 |
decreases expression increases methylation |
ISO |
mono-benzyl phthalate results in decreased expression of TP53 mRNA mono-benzyl phthalate results in increased methylation of TP53 promoter |
CTD |
PMID:35487445 |
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NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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G |
Alb |
albumin |
multiple interactions |
ISO |
ALB protein binds to and affects the transport of salicin |
CTD |
PMID:8831264 |
|
NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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G |
Tas2r118 |
taste receptor, type 2, member 118 |
multiple interactions increases activity |
ISO |
4-((diethylamino)sulfonyl)benzoic acid inhibits the reaction [salicin results in increased activity of TAS2R16 protein]; Probenecid inhibits the reaction [salicin results in increased activity of TAS2R16 protein] |
CTD |
PMID:21629661 |
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NCBI chr 4:52,449,208...52,450,107
Ensembl chr 4:52,449,208...52,450,107
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G |
Alb |
albumin |
multiple interactions |
ISO |
ALB protein binds to and affects the transport of salicyl alcohol |
CTD |
PMID:8831264 |
|
NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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G |
Bche |
butyrylcholinesterase |
multiple interactions |
ISO |
[2-(2-cresyl)-4H-1-3-2-benzodioxaphosphorin-2-oxide binds to and results in decreased activity of BCHE protein] which results in increased abundance of salicyl alcohol |
CTD |
PMID:22898212 |
|
NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
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G |
Sod2 |
superoxide dismutase 2 |
multiple interactions |
EXP |
salicyl alcohol inhibits the reaction [2,2'-azobis(2-amidinopropane) results in decreased activity of SOD2 protein] |
CTD |
PMID:19665455 |
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NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
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