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G |
Cyb5a |
cytochrome b5 type A |
multiple interactions |
EXP ISO |
CYB5A protein promotes the reaction [CYP1A1 protein results in increased oxidation of 1-phenylazo-2-naphthol] CYB5A protein inhibits the reaction [CYP2B6 protein results in increased oxidation of 1-phenylazo-2-naphthol]; CYB5A protein inhibits the reaction [CYP2C19 protein results in increased oxidation of 1-phenylazo-2-naphthol]; CYB5A protein inhibits the reaction [CYP2D6 protein results in increased oxidation of 1-phenylazo-2-naphthol]; CYB5A protein promotes the reaction [CYP1A1 protein results in increased oxidation of 1-phenylazo-2-naphthol]; CYB5A protein promotes the reaction [CYP1A2 protein results in increased oxidation of 1-phenylazo-2-naphthol]; CYB5A protein promotes the reaction [CYP2A6 protein results in increased oxidation of 1-phenylazo-2-naphthol]; CYB5A protein promotes the reaction [CYP3A4 protein results in increased oxidation of 1-phenylazo-2-naphthol] |
CTD |
PMID:17159775 PMID:19358889 |
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NCBI chr18:78,213,067...78,245,677
Ensembl chr18:78,202,342...78,258,535 Ensembl chr18:78,202,342...78,258,535
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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
multiple interactions increases oxidation increases expression |
ISO EXP |
CYB5A protein promotes the reaction [CYP1A1 protein results in increased oxidation of 1-phenylazo-2-naphthol]; CYP1A1 protein results in increased metabolism of and results in increased activity of 1-phenylazo-2-naphthol 1-phenylazo-2-naphthol promotes the reaction [aristolochic acid I results in increased expression of and results in increased activity of CYP1A1 protein]; 1-phenylazo-2-naphthol results in increased expression of and results in increased activity of CYP1A1 protein; [1-phenylazo-2-naphthol co-treated with aristolochic acid I] results in increased expression of CYP1A1 mRNA; [CYP1A1 protein co-treated with POR protein] results in increased metabolism of 1-phenylazo-2-naphthol; CYB5A protein promotes the reaction [CYP1A1 protein results in increased oxidation of 1-phenylazo-2-naphthol]; CYP1A1 protein results in increased metabolism of and results in increased activity of 1-phenylazo-2-naphthol 1-phenylazo-2-naphthol results in increased expression of CYP1A1 mRNA; 1-phenylazo-2-naphthol results in increased expression of CYP1A1 protein |
CTD |
PMID:12384524 PMID:15766589 PMID:17159775 PMID:18418879 PMID:23289503 PMID:24530354 PMID:26845733 More...
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NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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G |
Cyp1a2 |
cytochrome P450, family 1, subfamily a, polypeptide 2 |
multiple interactions increases oxidation increases expression |
ISO EXP |
CYB5A protein promotes the reaction [CYP1A2 protein results in increased oxidation of 1-phenylazo-2-naphthol] 1-phenylazo-2-naphthol affects the expression of and affects the activity of CYP1A2 protein; [1-phenylazo-2-naphthol co-treated with aristolochic acid I] results in increased expression of CYP1A2 mRNA; [aristolochic acid I co-treated with 1-phenylazo-2-naphthol] results in increased expression of and results in increased activity of CYP1A2 protein 1-phenylazo-2-naphthol results in increased expression of CYP1A2 mRNA |
CTD |
PMID:17159775 PMID:26845733 |
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NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
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G |
Cyp1b1 |
cytochrome P450, family 1, subfamily b, polypeptide 1 |
increases oxidation |
ISO |
CYP1B1 protein results in increased oxidation of 1-phenylazo-2-naphthol |
CTD |
PMID:17159775 |
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NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
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G |
Cyp2b3 |
cytochrome P450, family 2, subfamily b, polypeptide 3 |
increases oxidation multiple interactions |
ISO |
CYP2B6 protein results in increased oxidation of 1-phenylazo-2-naphthol CYB5A protein inhibits the reaction [CYP2B6 protein results in increased oxidation of 1-phenylazo-2-naphthol] |
CTD |
PMID:17159775 |
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NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
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G |
Cyp2c11 |
cytochrome P450, subfamily 2, polypeptide 11 |
decreases activity multiple interactions |
EXP |
1-phenylazo-2-naphthol results in decreased activity of CYP2C11 protein [aristolochic acid I co-treated with 1-phenylazo-2-naphthol] results in decreased activity of CYP2C11 protein |
CTD |
PMID:26845733 |
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NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066
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G |
Cyp2c6 |
cytochrome P450, family 2, subfamily C, polypeptide 6 |
multiple interactions increases oxidation |
ISO |
CYB5A protein inhibits the reaction [CYP2C19 protein results in increased oxidation of 1-phenylazo-2-naphthol] |
CTD |
PMID:17159775 |
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NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
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G |
Cyp2c79 |
cytochrome P450, family 2, subfamily c, polypeptide 79 |
increases oxidation |
ISO |
CYP2C8 protein results in increased oxidation of 1-phenylazo-2-naphthol |
CTD |
PMID:17159775 |
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G |
Cyp2d4 |
cytochrome P450, family 2, subfamily d, polypeptide 4 |
multiple interactions increases oxidation |
ISO |
CYB5A protein inhibits the reaction [CYP2D6 protein results in increased oxidation of 1-phenylazo-2-naphthol] |
CTD |
PMID:17159775 |
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NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
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G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
increases oxidation |
ISO |
CYP2E1 protein results in increased oxidation of 1-phenylazo-2-naphthol |
CTD |
PMID:17159775 |
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NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
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G |
Cyp3a2 |
cytochrome P450, family 3, subfamily a, polypeptide 2 |
increases oxidation multiple interactions |
ISO |
CYP3A4 protein results in increased oxidation of 1-phenylazo-2-naphthol CYB5A protein promotes the reaction [CYP3A4 protein results in increased oxidation of 1-phenylazo-2-naphthol] |
CTD |
PMID:17159775 PMID:19358889 |
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NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
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G |
F3 |
coagulation factor III, tissue factor |
increases expression |
ISO |
1-phenylazo-2-naphthol results in increased expression of F3 protein |
CTD |
PMID:25569083 |
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NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
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G |
Gstp1 |
glutathione S-transferase pi 1 |
increases expression |
EXP |
1-phenylazo-2-naphthol results in increased expression of GSTP1 mRNA |
CTD |
PMID:2563599 |
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NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
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G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
multiple interactions increases expression |
EXP |
1-phenylazo-2-naphthol results in increased expression of and results in increased activity of NQO1 protein; [1-phenylazo-2-naphthol co-treated with aristolochic acid I] results in increased expression of NQO1 mRNA; [aristolochic acid I co-treated with 1-phenylazo-2-naphthol] results in increased expression of and results in increased activity of NQO1 protein 1-phenylazo-2-naphthol results in increased expression of NQO1 mRNA |
CTD |
PMID:23289503 PMID:26845733 |
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NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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G |
Por |
cytochrome p450 oxidoreductase |
multiple interactions |
EXP |
[CYP1A1 protein co-treated with POR protein] results in increased metabolism of 1-phenylazo-2-naphthol |
CTD |
PMID:24530354 |
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NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
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