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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:methylcatechol
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Accession:CHEBI:25289 term browser browse the term
Definition:Any member of the class of catechols carrying one or more methyl substituents.
Synonyms:related_synonym: methylcatechols
 alt_id: CHEBI:25288


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3-methylcatechol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases expression ISO 3-methylcatechol results in increased expression of NFE2L2 mRNA CTD PMID:26862668 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO 3-methylcatechol inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein] CTD PMID:18499097 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO 3-methylcatechol inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; 3-methylcatechol inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:18499097 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO 3-methylcatechol inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein] CTD PMID:18499097 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO 3-methylcatechol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; 3-methylcatechol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] CTD PMID:18499097 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
4-methylcatechol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btc betacellulin decreases expression
multiple interactions		 EXP 4-methylcatechol results in decreased expression of BTC mRNA
4-methylcatechol results in decreased expression of and results in decreased secretion of BTC protein		 CTD PMID:29473434 NCBI chr14:16,708,447...16,746,961
Ensembl chr14:16,707,982...16,747,049 		JBrowse link
G Calca calcitonin-related polypeptide alpha multiple interactions ISO 4-methylcatechol inhibits the reaction [resiniferatoxin results in decreased expression of CALCA protein] CTD PMID:18219259 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105 		JBrowse link
G Comt catechol-O-methyltransferase increases methylation ISO
EXP		 COMT protein results in increased methylation of 4-methylcatechol CTD PMID:11160877 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Inhba inhibin subunit beta A decreases expression EXP 4-methylcatechol results in decreased expression of INHBA mRNA CTD PMID:29473434 NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982 		JBrowse link
G Ins1 insulin 1 decreases expression
multiple interactions		 EXP 4-methylcatechol results in decreased expression of INS1 mRNA
[4-methylcatechol co-treated with Glucose] results in increased secretion of INS1 protein		 CTD PMID:29473434 NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases expression ISO 4-methylcatechol results in increased expression of NFE2L2 mRNA CTD PMID:26862668 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Ngf nerve growth factor multiple interactions EXP 4-methylcatechol inhibits the reaction [Streptozocin results in decreased expression of NGF protein] CTD PMID:8195800 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO 4-methylcatechol inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; 4-methylcatechol inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:18499097 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO 4-methylcatechol inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein] CTD PMID:18499097 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Slc2a2 solute carrier family 2 member 2 decreases expression EXP 4-methylcatechol results in decreased expression of SLC2A2 mRNA CTD PMID:29473434 NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO 4-methylcatechol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; 4-methylcatechol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] CTD PMID:18499097 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Uchl1 ubiquitin C-terminal hydrolase L1 multiple interactions ISO 4-methylcatechol inhibits the reaction [resiniferatoxin results in decreased expression of UCHL1 protein] CTD PMID:18219259 NCBI chr14:41,485,031...41,495,590
Ensembl chr14:41,485,031...41,495,590 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19890
    chemical entity 19867
      molecular entity 19867
        polyatomic entity 19819
          heteroatomic molecular entity 19776
            hydroxides 19334
              organic hydroxy compound 18963
                phenols 18641
                  benzenediols 9163
                    catechols 3426
                      methylcatechol 13
                        3-chloro-4-methylcatechol 0
                        3-methylcatechol + 5
                        3-tert-Butyl-5-methylcatechol 0
                        4-chloro-3-methylcatechol 0
                        4-methyl-3-nitrocatechol 0
                        4-methylcatechol + 12
                        5-chloro-3-methylcatechol 0
                        5-methyl-3-nitrocatechol 0
                        tricholignan A 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19890
    subatomic particle 19867
      composite particle 19888
        hadron 19888
          baryon 19888
            nucleon 19867
              atomic nucleus 19888
                atom 19888
                  main group element atom 19806
                    p-block element atom 19806
                      carbon group element atom 19746
                        carbon atom 19743
                          organic molecular entity 19743
                            organic molecule 19714
                              organic cyclic compound 19485
                                organic aromatic compound 19350
                                  phenols 18641
                                    benzenediols 9163
                                      catechols 3426
                                        methylcatechol 13
                                          3-chloro-4-methylcatechol 0
                                          3-methylcatechol + 5
                                          3-tert-Butyl-5-methylcatechol 0
                                          4-chloro-3-methylcatechol 0
                                          4-methyl-3-nitrocatechol 0
                                          4-methylcatechol + 12
                                          5-chloro-3-methylcatechol 0
                                          5-methyl-3-nitrocatechol 0
                                          tricholignan A 0
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