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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:4-methylcatechol
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Accession:CHEBI:17254 term browser browse the term
Definition:A methylcatechol having a single methyl substituent at the 4-position. It has been isolated from Picea abies.
Synonyms:related_synonym: 1,2-dihydroxy-4-methylbenzene;   2-Hydroxy-4-methylphenol;   3,4-dihydroxytoluene;   4-Methyl-1,2-dihydroxybenzene;   4-Methylpyrocatechol;   4-methyl-1,2-benzenediol;   4-methylbenzene-1,2-diol;   Formula=C7H8O2;   Homocatechol;   Homopyrocatechol;   InChI=1S/C7H8O2/c1-5-2-3-6(8)7(9)4-5/h2-4,8-9H,1H3;   InChIKey=ZBCATMYQYDCTIZ-UHFFFAOYSA-N;   SMILES=Cc1ccc(O)c(O)c1;   Toluene-3,4-diol;   p-Methylcatechol;   p-Methylpyrocatechol
 alt_id: CHEBI:12025;   CHEBI:1897;   CHEBI:20442;   CHEBI:43962
 xref: CAS:452-86-8;   DrugBank:DB04120;   HMDB:HMDB0000873;   KEGG:C06730;   KNApSAcK:C00002660
 xref_mesh: MESH:C018599
 xref: PDBeChem:MCT;   PMID:18499097;   Reaxys:636512;   UM-BBD_compID:c0126;   Wikipedia:4-Methylcatechol


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4-methylcatechol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calca calcitonin-related polypeptide alpha multiple interactions ISO 4-methylcatechol inhibits the reaction [resiniferatoxin results in decreased expression of CALCA protein] CTD PMID:18219259 NCBI chr 1:184,184,018...184,188,922
Ensembl chr 1:184,184,020...184,188,911
JBrowse link
G Comt catechol-O-methyltransferase increases methylation ISO
EXP
COMT protein results in increased methylation of 4-methylcatechol CTD PMID:11160877 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
JBrowse link
G Ngf nerve growth factor multiple interactions EXP 4-methylcatechol inhibits the reaction [Streptozocin results in decreased expression of NGF protein] CTD PMID:8195800 NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO 4-methylcatechol inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; 4-methylcatechol inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:18499097 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO 4-methylcatechol inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein] CTD PMID:18499097 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO 4-methylcatechol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; 4-methylcatechol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] CTD PMID:18499097 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Uchl1 ubiquitin C-terminal hydrolase L1 multiple interactions ISO 4-methylcatechol inhibits the reaction [resiniferatoxin results in decreased expression of UCHL1 protein] CTD PMID:18219259 NCBI chr14:43,133,224...43,143,942
Ensembl chr14:43,133,218...43,143,973
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19781
    role 19726
      chemical role 19270
        antioxidant 14275
          4-methylcatechol 7
            3-chloro-4-methylcatechol 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19781
    subatomic particle 19779
      composite particle 19779
        hadron 19779
          baryon 19779
            nucleon 19779
              atomic nucleus 19779
                atom 19779
                  main group element atom 19669
                    p-block element atom 19669
                      carbon group element atom 19588
                        carbon atom 19578
                          organic molecular entity 19578
                            organic molecule 19510
                              organic cyclic compound 19337
                                organic aromatic compound 19162
                                  phenols 18140
                                    benzenediols 6101
                                      catechols 3176
                                        methylcatechol 8
                                          4-methylcatechol 7
                                            3-chloro-4-methylcatechol 0
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