Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:4-methylcatechol
go back to main search page
Accession:CHEBI:17254 term browser browse the term
Definition:A methylcatechol having a single methyl substituent at the 4-position. It has been isolated from Picea abies.
Synonyms:related_synonym: 1,2-dihydroxy-4-methylbenzene;   2-Hydroxy-4-methylphenol;   3,4-dihydroxytoluene;   4-Methyl-1,2-dihydroxybenzene;   4-Methylpyrocatechol;   4-methyl-1,2-benzenediol;   4-methylbenzene-1,2-diol;   Formula=C7H8O2;   Homocatechol;   Homopyrocatechol;   InChI=1S/C7H8O2/c1-5-2-3-6(8)7(9)4-5/h2-4,8-9H,1H3;   InChIKey=ZBCATMYQYDCTIZ-UHFFFAOYSA-N;   SMILES=Cc1ccc(O)c(O)c1;   Toluene-3,4-diol;   p-Methylcatechol;   p-Methylpyrocatechol
 alt_id: CHEBI:12025;   CHEBI:1897;   CHEBI:20442;   CHEBI:43962
 xref: CAS:452-86-8;   DrugBank:DB04120;   HMDB:HMDB0000873;   KEGG:C06730;   KNApSAcK:C00002660
 xref_mesh: MESH:C018599
 xref: PDBeChem:MCT;   PMID:18499097;   Reaxys:636512;   UM-BBD_compID:c0126;   Wikipedia:4-Methylcatechol



show annotations for term's descendants           Sort by:
 
4-methylcatechol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btc betacellulin decreases expression
multiple interactions
EXP 4-methylcatechol results in decreased expression of BTC mRNA
4-methylcatechol results in decreased expression of and results in decreased secretion of BTC protein
CTD PMID:29473434 NCBI chr14:16,708,447...16,746,961
Ensembl chr14:16,707,982...16,747,049
JBrowse link
G Calca calcitonin-related polypeptide alpha multiple interactions ISO 4-methylcatechol inhibits the reaction [resiniferatoxin results in decreased expression of CALCA protein] CTD PMID:18219259 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
JBrowse link
G Comt catechol-O-methyltransferase increases methylation ISO
EXP
COMT protein results in increased methylation of 4-methylcatechol CTD PMID:11160877 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
JBrowse link
G Inhba inhibin subunit beta A decreases expression EXP 4-methylcatechol results in decreased expression of INHBA mRNA CTD PMID:29473434 NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982
JBrowse link
G Ngf nerve growth factor multiple interactions EXP 4-methylcatechol inhibits the reaction [Streptozocin results in decreased expression of NGF protein] CTD PMID:8195800 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO 4-methylcatechol inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; 4-methylcatechol inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:18499097 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO 4-methylcatechol inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein] CTD PMID:18499097 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Slc2a2 solute carrier family 2 member 2 decreases expression EXP 4-methylcatechol results in decreased expression of SLC2A2 mRNA CTD PMID:29473434 NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO 4-methylcatechol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; 4-methylcatechol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] CTD PMID:18499097 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Uchl1 ubiquitin C-terminal hydrolase L1 multiple interactions ISO 4-methylcatechol inhibits the reaction [resiniferatoxin results in decreased expression of UCHL1 protein] CTD PMID:18219259 NCBI chr14:41,485,033...41,495,590
Ensembl chr14:41,485,031...41,495,590
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20050
    role 20001
      chemical role 19530
        antioxidant 14499
          4-methylcatechol 10
            3-chloro-4-methylcatechol 0
            tricholignan A 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20050
    subatomic particle 20048
      composite particle 20048
        hadron 20048
          baryon 20048
            nucleon 20048
              atomic nucleus 20048
                atom 20048
                  main group element atom 19948
                    p-block element atom 19948
                      carbon group element atom 19872
                        carbon atom 19863
                          organic molecular entity 19863
                            organic molecule 19809
                              organic cyclic compound 19572
                                organic aromatic compound 19407
                                  phenols 18486
                                    benzenediols 6490
                                      catechols 3230
                                        methylcatechol 11
                                          4-methylcatechol 10
                                            3-chloro-4-methylcatechol 0
                                            tricholignan A 0
paths to the root