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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Deoxycorticosterone acetate
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Accession:CHEBI:34671 term browser browse the term
Definition:A corticosteroid hormone that has formula C23H32O4.
Synonyms:related_synonym: 21-Acetoxypregn-4-ene-3,20-dione;   Formula=C23H32O4;   InChI=1S/C23H32O4/c1-14(24)27-13-21(26)20-7-6-18-17-5-4-15-12-16(25)8-10-22(15,2)19(17)9-11-23(18,20)3/h12,17-20H,4-11,13H2,1-3H3/t17-,18-,19-,20+,22-,23-/m0/s1;   InChIKey=VPGRYOFKCNULNK-ACXQXYJUSA-N;   Percotol;   SMILES=CC(=O)OCC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C;   cortexone acetate;   decosteron;   decosterone;   deoxycortone acetate;   desoxycortone acetate;   sincortex
 alt_id: MESH:D064791
 xref: CAS:56-47-3;   Drug_Central:821;   KEGG:C14554;   KEGG:D03698
 xref_mesh: MESH:D064791



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Deoxycorticosterone acetate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions
decreases expression
EXP chromium mesoporphyrin inhibits the reaction [heme arginate inhibits the reaction [Desoxycorticosterone Acetate results in decreased expression of ADIPOQ protein]]; chromium mesoporphyrin promotes the reaction [Desoxycorticosterone Acetate results in decreased expression of ADIPOQ protein]; heme arginate inhibits the reaction [Desoxycorticosterone Acetate results in decreased expression of ADIPOQ protein] CTD PMID:23089228 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Alox15 arachidonate 15-lipoxygenase multiple interactions ISO ALOX15 protein affects the susceptibility to [Desoxycorticosterone Acetate co-treated with Sodium Chloride, Dietary] CTD PMID:22467300 NCBI chr10:55,060,169...55,068,885
Ensembl chr10:55,060,412...55,068,874
JBrowse link
G Anxa1 annexin A1 multiple interactions EXP [Desoxycorticosterone Acetate co-treated with Sodium Chloride, Dietary co-treated with Potassium Chloride] results in increased expression of ANXA1 mRNA CTD PMID:22228705 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
JBrowse link
G Apoe apolipoprotein E multiple interactions EXP [Desoxycorticosterone Acetate co-treated with Sodium Chloride, Dietary co-treated with Potassium Chloride] results in increased expression of APOE mRNA CTD PMID:22228705 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Aqp1 aquaporin 1 multiple interactions EXP [Desoxycorticosterone Acetate co-treated with Sodium Chloride, Dietary co-treated with Potassium Chloride] results in decreased expression of AQP1 mRNA CTD PMID:22228705 NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690
JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 multiple interactions EXP [Desoxycorticosterone Acetate co-treated with Sodium Chloride, Dietary] results in decreased expression of ATP2A2 protein; Metformin inhibits the reaction [[Desoxycorticosterone Acetate co-treated with Sodium Chloride, Dietary] results in decreased expression of ATP2A2 protein] CTD PMID:30290168 NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101
JBrowse link
G Cat catalase multiple interactions EXP [Desoxycorticosterone Acetate co-treated with Sodium Chloride, Dietary co-treated with Potassium Chloride] results in decreased expression of CAT mRNA CTD PMID:22228705 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression
multiple interactions
EXP Desoxycorticosterone Acetate results in increased expression of CCL2 protein
heme arginate inhibits the reaction [Desoxycorticosterone Acetate results in increased expression of CCL2 protein]
CTD PMID:23089228 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Cd38 CD38 molecule multiple interactions ISO CD38 gene mutant form promotes the reaction [[Desoxycorticosterone Acetate co-treated with Sodium Chloride] affects the localization of [NPHS2 protein co-treated with CDH3 protein]]; CD38 gene mutant form promotes the reaction [[Desoxycorticosterone Acetate co-treated with Sodium Chloride] affects the localization of [NPHS2 protein co-treated with TJP1 protein]] CTD PMID:21992601 NCBI chr14:67,172,062...67,212,328
Ensembl chr14:67,172,063...67,211,986
JBrowse link
G Cd68 Cd68 molecule multiple interactions ISO [Desoxycorticosterone Acetate co-treated with Sodium Chloride] results in increased expression of CD68 mRNA; CXCR2 gene mutant form inhibits the reaction [[Desoxycorticosterone Acetate co-treated with Sodium Chloride] results in increased expression of CD68 mRNA] CTD PMID:27678262 NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697
JBrowse link
G Cdh3 cadherin 3 multiple interactions ISO [Desoxycorticosterone Acetate co-treated with Sodium Chloride] affects the localization of [NPHS2 protein co-treated with CDH3 protein]; CD38 gene mutant form promotes the reaction [[Desoxycorticosterone Acetate co-treated with Sodium Chloride] affects the localization of [NPHS2 protein co-treated with CDH3 protein]] CTD PMID:21992601 NCBI chr19:34,393,596...34,444,084
Ensembl chr19:34,393,727...34,444,084
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A increases expression
multiple interactions
affects localization
EXP Desoxycorticosterone Acetate results in increased expression of CDKN2A mRNA; Desoxycorticosterone Acetate results in increased expression of CDKN2A protein
[Hydrochlorothiazide co-treated with Hydralazine co-treated with Reserpine] inhibits the reaction [Desoxycorticosterone Acetate affects the localization of CDKN2A protein]; [Hydrochlorothiazide co-treated with Hydralazine co-treated with Reserpine] inhibits the reaction [Desoxycorticosterone Acetate results in increased expression of CDKN2A mRNA]; Spironolactone inhibits the reaction [Desoxycorticosterone Acetate affects the localization of CDKN2A protein]; Spironolactone inhibits the reaction [Desoxycorticosterone Acetate results in increased expression of CDKN2A mRNA]
CTD PMID:18504326 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
JBrowse link
G Cs citrate synthase multiple interactions EXP [Desoxycorticosterone Acetate co-treated with Sodium Chloride co-treated with cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester] results in increased expression of CS protein CTD PMID:29621749 NCBI chr 7:758,074...791,421
Ensembl chr 7:758,345...791,421
JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 multiple interactions ISO CXCR2 gene mutant form inhibits the reaction [[Desoxycorticosterone Acetate co-treated with Sodium Chloride] results in increased expression of CD68 mRNA]; CXCR2 gene mutant form inhibits the reaction [[Desoxycorticosterone Acetate co-treated with Sodium Chloride] results in increased expression of CYBA mRNA]; CXCR2 gene mutant form inhibits the reaction [[Desoxycorticosterone Acetate co-treated with Sodium Chloride] results in increased expression of CYBB mRNA]; CXCR2 gene mutant form inhibits the reaction [[Desoxycorticosterone Acetate co-treated with Sodium Chloride] results in increased expression of IL1B mRNA]; CXCR2 gene mutant form inhibits the reaction [[Desoxycorticosterone Acetate co-treated with Sodium Chloride] results in increased expression of IL6 mRNA]; CXCR2 gene mutant form inhibits the reaction [[Desoxycorticosterone Acetate co-treated with Sodium Chloride] results in increased expression of NOX1 mRNA]; CXCR2 gene mutant form inhibits the reaction [[Desoxycorticosterone Acetate co-treated with Sodium Chloride] results in increased expression of NOX4 mRNA]; CXCR2 gene mutant form inhibits the reaction [[Desoxycorticosterone Acetate co-treated with Sodium Chloride] results in increased expression of TNF mRNA]; CXCR2 gene mutant form inhibits the reaction [[Desoxycorticosterone Acetate co-treated with Sodium Chloride] results in increased expression of VCAM1 mRNA] CTD PMID:27678262 NCBI chr 9:75,729,493...75,735,868
Ensembl chr 9:75,729,115...75,739,425
JBrowse link
G Cyba cytochrome b-245 alpha chain multiple interactions ISO [Desoxycorticosterone Acetate co-treated with Sodium Chloride] results in increased expression of CYBA mRNA; CXCR2 gene mutant form inhibits the reaction [[Desoxycorticosterone Acetate co-treated with Sodium Chloride] results in increased expression of CYBA mRNA] CTD PMID:27678262 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
JBrowse link
G Cybb cytochrome b-245 beta chain multiple interactions ISO [Desoxycorticosterone Acetate co-treated with Sodium Chloride] results in increased expression of CYBB mRNA; CXCR2 gene mutant form inhibits the reaction [[Desoxycorticosterone Acetate co-treated with Sodium Chloride] results in increased expression of CYBB mRNA]; CYBB protein affects the susceptibility to [Desoxycorticosterone Acetate co-treated with Sodium Chloride, Dietary] CTD PMID:21368743 PMID:27678262 NCBI chr  X:13,358,101...13,392,570
Ensembl chr  X:13,359,430...13,392,586
JBrowse link
G Des desmin multiple interactions ISO [Desoxycorticosterone Acetate co-treated with Sodium Chloride] results in increased expression of DES protein CTD PMID:21992601 NCBI chr 9:76,850,979...76,858,695
Ensembl chr 9:76,850,982...76,858,699
JBrowse link
G Edn1 endothelin 1 multiple interactions
increases expression
EXP [Desoxycorticosterone Acetate co-treated with Sodium Chloride, Dietary] results in increased expression of EDN1 protein; [Desoxycorticosterone Acetate co-treated with Sodium Chloride] results in increased expression of EDN1 mRNA; [Desoxycorticosterone Acetate co-treated with Sodium Chloride] results in increased expression of EDN1 protein; [Ozone co-treated with Oxygen] inhibits the reaction [[Desoxycorticosterone Acetate co-treated with Sodium Chloride] results in increased expression of EDN1 mRNA]; [Ozone co-treated with Oxygen] inhibits the reaction [[Desoxycorticosterone Acetate co-treated with Sodium Chloride] results in increased expression of EDN1 protein]; chromium mesoporphyrin inhibits the reaction [heme arginate inhibits the reaction [Desoxycorticosterone Acetate results in increased expression of EDN1 protein]]; chromium mesoporphyrin promotes the reaction [Desoxycorticosterone Acetate results in increased expression of EDN1 protein]; heme arginate inhibits the reaction [Desoxycorticosterone Acetate results in increased expression of EDN1 protein] CTD PMID:7721389 PMID:23089228 PMID:26550192 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Ednra endothelin receptor type A multiple interactions EXP [Desoxycorticosterone Acetate co-treated with Sodium Chloride] results in increased expression of EDNRA mRNA; [Ozone co-treated with Oxygen] inhibits the reaction [[Desoxycorticosterone Acetate co-treated with Sodium Chloride] results in increased expression of EDNRA mRNA] CTD PMID:26550192 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049
JBrowse link
G Ednrb endothelin receptor type B multiple interactions EXP [Desoxycorticosterone Acetate co-treated with Sodium Chloride] results in decreased expression of EDNRB mRNA; [Ozone co-treated with Oxygen] inhibits the reaction [[Desoxycorticosterone Acetate co-treated with Sodium Chloride] results in decreased expression of EDNRB mRNA] CTD PMID:26550192 NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115
JBrowse link
G Fxyd2 FXYD domain-containing ion transport regulator 2 multiple interactions EXP [Desoxycorticosterone Acetate co-treated with Sodium Chloride, Dietary co-treated with Potassium Chloride] results in decreased expression of FXYD2 mRNA CTD PMID:22228705 NCBI chr 8:45,712,901...45,720,032
Ensembl chr 8:45,712,903...45,720,203
JBrowse link
G Gcg glucagon multiple interactions EXP [Desoxycorticosterone Acetate co-treated with Sodium Chloride, Dietary co-treated with Potassium Chloride] results in decreased expression of GCG mRNA CTD PMID:22228705 NCBI chr 3:47,113,914...47,122,958
Ensembl chr 3:47,113,914...47,122,929
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions EXP [Desoxycorticosterone Acetate co-treated with Sodium Chloride, Dietary co-treated with Potassium Chloride] results in decreased expression of GCLC mRNA CTD PMID:22228705 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Glp1r glucagon-like peptide 1 receptor multiple interactions EXP [Desoxycorticosterone Acetate co-treated with Sodium Chloride, Dietary co-treated with Potassium Chloride] results in decreased expression of GLP1R mRNA CTD PMID:22228705 NCBI chr20:8,972,004...9,010,241
Ensembl chr20:8,972,004...9,010,241
JBrowse link
G Gsta5 glutathione S-transferase alpha 5 multiple interactions EXP [Desoxycorticosterone Acetate co-treated with Sodium Chloride, Dietary co-treated with Potassium Chloride] results in decreased expression of GSTA5 mRNA CTD PMID:22228705 NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472
JBrowse link
G Gstt1 glutathione S-transferase theta 1 multiple interactions EXP [Desoxycorticosterone Acetate co-treated with Sodium Chloride, Dietary co-treated with Potassium Chloride] results in decreased expression of GSTT1 mRNA CTD PMID:22228705 NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585
JBrowse link
G Gstt2 glutathione S-transferase theta 2 multiple interactions EXP [Desoxycorticosterone Acetate co-treated with Sodium Chloride, Dietary co-treated with Potassium Chloride] results in decreased expression of GSTT2 mRNA CTD PMID:22228705 NCBI chr20:12,819,617...12,823,288
Ensembl chr20:12,819,170...12,823,288
JBrowse link
G Hdac8 histone deacetylase 8 increases activity EXP Deoxycorticosterone acetate increases activity of Hdac8 protein in the heart RGD PMID:23868068 RGD:9681716 NCBI chr  X:67,385,288...67,593,014
Ensembl chr  X:67,385,289...67,592,923
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions EXP [chromium mesoporphyrin results in decreased activity of HMOX1 protein] inhibits the reaction [Desoxycorticosterone Acetate results in decreased susceptibility to Acetylcholine]; Desoxycorticosterone Acetate results in increased expression of and results in increased activity of HMOX1 protein CTD PMID:14693679 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions
increases expression
EXP heme arginate inhibits the reaction [Desoxycorticosterone Acetate results in increased expression of ICAM1 protein] CTD PMID:23089228 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions EXP [Desoxycorticosterone Acetate co-treated with Sodium Chloride, Dietary co-treated with Potassium Chloride] results in decreased expression of IGF1 mRNA CTD PMID:22228705 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO [Desoxycorticosterone Acetate co-treated with Sodium Chloride] results in increased expression of IL1B mRNA; CXCR2 gene mutant form inhibits the reaction [[Desoxycorticosterone Acetate co-treated with Sodium Chloride] results in increased expression of IL1B mRNA] CTD PMID:27678262 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions ISO [Desoxycorticosterone Acetate co-treated with Sodium Chloride] results in increased expression of IL6 mRNA; CXCR2 gene mutant form inhibits the reaction [[Desoxycorticosterone Acetate co-treated with Sodium Chloride] results in increased expression of IL6 mRNA] CTD PMID:27678262 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ins1 insulin 1 multiple interactions
decreases expression
EXP [Desoxycorticosterone Acetate co-treated with Sodium Chloride] results in decreased expression of INS1 protein; chromium mesoporphyrin inhibits the reaction [heme arginate inhibits the reaction [Desoxycorticosterone Acetate results in decreased expression of INS1 protein]]; chromium mesoporphyrin promotes the reaction [Desoxycorticosterone Acetate results in decreased expression of INS1 protein]; cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester inhibits the reaction [[Desoxycorticosterone Acetate co-treated with Sodium Chloride] results in decreased expression of INS1 protein]; heme arginate inhibits the reaction [Desoxycorticosterone Acetate results in decreased expression of INS1 protein] CTD PMID:23089228 PMID:29621749 NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
JBrowse link
G Itm2b integral membrane protein 2B multiple interactions EXP [Desoxycorticosterone Acetate co-treated with Sodium Chloride, Dietary co-treated with Potassium Chloride] results in decreased expression of ITM2B mRNA CTD PMID:22228705 NCBI chr15:48,545,998...48,568,904
Ensembl chr15:48,546,001...48,568,917
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
EXP chromium mesoporphyrin inhibits the reaction [heme arginate inhibits the reaction [Desoxycorticosterone Acetate results in increased expression of JUN mRNA]]; chromium mesoporphyrin promotes the reaction [Desoxycorticosterone Acetate results in increased expression of JUN mRNA]; heme arginate inhibits the reaction [Desoxycorticosterone Acetate results in increased expression of JUN mRNA]; heme arginate inhibits the reaction [Desoxycorticosterone Acetate results in increased expression of JUN protein]
Desoxycorticosterone Acetate results in increased expression of JUN mRNA; Desoxycorticosterone Acetate results in increased expression of JUN protein
CTD PMID:23089228 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Kcnj1 potassium inwardly-rectifying channel, subfamily J, member 1 multiple interactions EXP [Desoxycorticosterone Acetate co-treated with Sodium Chloride, Dietary co-treated with Potassium Chloride] results in decreased expression of KCNJ1 mRNA CTD PMID:22228705 NCBI chr 8:30,779,883...30,808,607
Ensembl chr 8:30,753,617...30,813,796
JBrowse link
G Lpl lipoprotein lipase multiple interactions EXP [Desoxycorticosterone Acetate co-treated with Sodium Chloride, Dietary co-treated with Potassium Chloride] results in decreased expression of LPL mRNA CTD PMID:22228705 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions
increases expression
EXP chromium mesoporphyrin inhibits the reaction [heme arginate inhibits the reaction [Desoxycorticosterone Acetate results in increased expression of MAPK9 mRNA]]; chromium mesoporphyrin promotes the reaction [Desoxycorticosterone Acetate results in increased expression of MAPK9 mRNA]; heme arginate inhibits the reaction [Desoxycorticosterone Acetate results in increased expression of MAPK9 mRNA] CTD PMID:23089228 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
JBrowse link
G Mdh1 malate dehydrogenase 1 multiple interactions EXP [Desoxycorticosterone Acetate co-treated with Sodium Chloride, Dietary co-treated with Potassium Chloride] results in decreased expression of MDH1 mRNA CTD PMID:22228705 NCBI chr14:95,630,625...95,645,920
Ensembl chr14:95,630,306...95,645,925
JBrowse link
G Mir146a microRNA 146a multiple interactions EXP [Desoxycorticosterone Acetate co-treated with Sodium Chloride, Dietary] results in decreased expression of MIR146A mRNA; Metformin inhibits the reaction [[Desoxycorticosterone Acetate co-treated with Sodium Chloride, Dietary] results in decreased expression of MIR146A mRNA] CTD PMID:30290168 NCBI chr10:27,848,516...27,848,610
Ensembl chr10:27,848,516...27,848,610
JBrowse link
G Mir155 microRNA 155 multiple interactions EXP [Desoxycorticosterone Acetate co-treated with Sodium Chloride, Dietary] results in increased expression of MIR155 mRNA; Metformin inhibits the reaction [[Desoxycorticosterone Acetate co-treated with Sodium Chloride, Dietary] results in increased expression of MIR155 mRNA] CTD PMID:30290168 NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718
JBrowse link
G Mir99b microRNA 99b multiple interactions EXP [Desoxycorticosterone Acetate co-treated with Sodium Chloride, Dietary] results in decreased expression of MIR99B mRNA; Metformin inhibits the reaction [[Desoxycorticosterone Acetate co-treated with Sodium Chloride, Dietary] results in decreased expression of MIR99B mRNA] CTD PMID:30290168 NCBI chr 1:58,677,015...58,677,084
Ensembl chr 1:58,677,011...58,677,090
JBrowse link
G Ncf1 neutrophil cytosolic factor 1 multiple interactions ISO NCF1 protein affects the susceptibility to [Desoxycorticosterone Acetate co-treated with Sodium Chloride, Dietary] CTD PMID:21368743 NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646
JBrowse link
G Nfkb2 nuclear factor kappa B subunit 2 increases expression
multiple interactions
EXP Desoxycorticosterone Acetate results in increased expression of NFKB2 protein
heme arginate inhibits the reaction [Desoxycorticosterone Acetate results in increased expression of NFKB2 protein]
CTD PMID:23089228 NCBI chr 1:245,164,586...245,173,225
Ensembl chr 1:245,165,950...245,173,213
JBrowse link
G Nherf2 NHERF family PDZ scaffold protein 2 multiple interactions EXP [Desoxycorticosterone Acetate co-treated with Sodium Chloride, Dietary co-treated with Potassium Chloride] results in decreased expression of NHERF2 mRNA CTD PMID:22228705 NCBI chr10:13,662,461...13,672,975
Ensembl chr10:13,662,461...13,673,049
JBrowse link
G Nox1 NADPH oxidase 1 multiple interactions ISO [Desoxycorticosterone Acetate co-treated with Sodium Chloride] results in increased expression of NOX1 mRNA; CXCR2 gene mutant form inhibits the reaction [[Desoxycorticosterone Acetate co-treated with Sodium Chloride] results in increased expression of NOX1 mRNA] CTD PMID:27678262 NCBI chr  X:97,279,058...97,332,291
Ensembl chr  X:97,279,056...97,302,236
JBrowse link
G Nox4 NADPH oxidase 4 multiple interactions ISO [Desoxycorticosterone Acetate co-treated with Sodium Chloride] results in increased expression of NOX4 mRNA; CXCR2 gene mutant form inhibits the reaction [[Desoxycorticosterone Acetate co-treated with Sodium Chloride] results in increased expression of NOX4 mRNA] CTD PMID:27678262 NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406
JBrowse link
G Nphs2 NPHS2 stomatin family member, podocin multiple interactions ISO [Desoxycorticosterone Acetate co-treated with Sodium Chloride] affects the localization of [NPHS2 protein co-treated with CDH3 protein]; [Desoxycorticosterone Acetate co-treated with Sodium Chloride] affects the localization of [NPHS2 protein co-treated with TJP1 protein]; [Desoxycorticosterone Acetate co-treated with Sodium Chloride] results in increased expression of NPHS2 protein; CD38 gene mutant form promotes the reaction [[Desoxycorticosterone Acetate co-treated with Sodium Chloride] affects the localization of [NPHS2 protein co-treated with CDH3 protein]]; CD38 gene mutant form promotes the reaction [[Desoxycorticosterone Acetate co-treated with Sodium Chloride] affects the localization of [NPHS2 protein co-treated with TJP1 protein]] CTD PMID:21992601 NCBI chr13:68,448,720...68,461,312
Ensembl chr13:68,448,926...68,461,313
JBrowse link
G Nptn neuroplastin multiple interactions EXP [Desoxycorticosterone Acetate co-treated with Sodium Chloride, Dietary co-treated with Potassium Chloride] results in decreased expression of NPTN mRNA CTD PMID:22228705 NCBI chr 8:58,996,873...59,063,402
Ensembl chr 8:58,996,887...59,063,401
JBrowse link
G Pdhx pyruvate dehydrogenase complex, component X multiple interactions EXP [Desoxycorticosterone Acetate co-treated with Sodium Chloride co-treated with cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester] results in increased expression of PDHX protein; [Desoxycorticosterone Acetate co-treated with Sodium Chloride] results in increased expression of PDHX protein CTD PMID:29621749 NCBI chr 3:89,372,248...89,431,779
Ensembl chr 3:89,371,497...89,431,773
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
increases expression
EXP chromium mesoporphyrin inhibits the reaction [heme arginate inhibits the reaction [Desoxycorticosterone Acetate results in increased expression of RELA mRNA]]; chromium mesoporphyrin promotes the reaction [Desoxycorticosterone Acetate results in increased expression of RELA mRNA]; heme arginate inhibits the reaction [Desoxycorticosterone Acetate results in increased expression of RELA mRNA] CTD PMID:23089228 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Ren renin multiple interactions EXP [Desoxycorticosterone Acetate co-treated with Sodium Chloride] results in decreased expression of REN protein; [Ozone co-treated with Oxygen] inhibits the reaction [[Desoxycorticosterone Acetate co-treated with Sodium Chloride] results in decreased expression of REN protein] CTD PMID:26550192 NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489
JBrowse link
G Slc2a1 solute carrier family 2 member 1 multiple interactions EXP [Desoxycorticosterone Acetate co-treated with Sodium Chloride co-treated with cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester] results in increased expression of SLC2A1 protein CTD PMID:29621749 NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416
JBrowse link
G Slc2a4 solute carrier family 2 member 4 multiple interactions EXP [Desoxycorticosterone Acetate co-treated with Sodium Chloride co-treated with cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester] results in increased expression of SLC2A4 protein CTD PMID:29621749 NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565
JBrowse link
G Tjp1 tight junction protein 1 multiple interactions ISO [Desoxycorticosterone Acetate co-treated with Sodium Chloride] affects the localization of [NPHS2 protein co-treated with TJP1 protein]; CD38 gene mutant form promotes the reaction [[Desoxycorticosterone Acetate co-treated with Sodium Chloride] affects the localization of [NPHS2 protein co-treated with TJP1 protein]] CTD PMID:21992601 NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO [Desoxycorticosterone Acetate co-treated with Sodium Chloride] results in increased expression of TNF mRNA; CXCR2 gene mutant form inhibits the reaction [[Desoxycorticosterone Acetate co-treated with Sodium Chloride] results in increased expression of TNF mRNA] CTD PMID:27678262 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tp53 tumor protein p53 multiple interactions EXP [Desoxycorticosterone Acetate co-treated with Sodium Chloride, Dietary co-treated with Potassium Chloride] results in increased expression of TP53 mRNA CTD PMID:22228705 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tpm1 tropomyosin 1 multiple interactions EXP [Desoxycorticosterone Acetate co-treated with Sodium Chloride, Dietary co-treated with Potassium Chloride] results in increased expression of TPM1 mRNA CTD PMID:22228705 NCBI chr 8:67,635,479...67,662,330
Ensembl chr 8:67,635,479...67,662,802
JBrowse link
G Umod uromodulin multiple interactions EXP [Desoxycorticosterone Acetate co-treated with Sodium Chloride, Dietary co-treated with Potassium Chloride] results in decreased expression of UMOD mRNA CTD PMID:22228705 NCBI chr 1:173,816,341...173,829,681
Ensembl chr 1:173,816,339...173,830,302
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO [Desoxycorticosterone Acetate co-treated with Sodium Chloride] results in increased expression of VCAM1 mRNA; CXCR2 gene mutant form inhibits the reaction [[Desoxycorticosterone Acetate co-treated with Sodium Chloride] results in increased expression of VCAM1 mRNA] CTD PMID:27678262 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19834
    role 19810
      biological role 19808
        molecular messenger 18638
          hormone 18485
            steroid hormone 7895
              corticosteroid hormone 5392
                Deoxycorticosterone acetate 61
Path 2
Term Annotations click to browse term
  CHEBI ontology 19834
    subatomic particle 19832
      composite particle 19832
        hadron 19832
          baryon 19832
            nucleon 19832
              atomic nucleus 19832
                atom 19832
                  main group element atom 19782
                    p-block element atom 19782
                      carbon group element atom 19731
                        carbon atom 19727
                          organic molecular entity 19727
                            organic molecule 19680
                              organic cyclic compound 19493
                                organic polycyclic compound 17251
                                  steroid 14695
                                    steroid hormone 7895
                                      corticosteroid hormone 5392
                                        Deoxycorticosterone acetate 61
paths to the root