Gene: Slc9a3r2 (SLC9A3 regulator 2) Rattus norvegicus
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Symbol: Slc9a3r2
Name: SLC9A3 regulator 2
Description: ENCODES a protein that exhibits channel regulator activity; low-density lipoprotein particle receptor binding; PDZ domain binding; INVOLVED IN inner ear development; positive regulation of membrane potential; negative regulation of phosphatidylinositol 3-kinase signaling (ortholog); PARTICIPATES IN parathyroid hormone signaling pathway; aldosterone signaling pathway; ASSOCIATED WITH Hypertension; hypertension; FOUND IN apical plasma membrane; cytoplasm; nucleus; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: E3karp; na(+)/H(+) exchange regulatory cofactor NHE-RF2; NHE3 kinase A regulatory protein; NHE3 kinase A regulatory protein E3KARP; NHERF-2; SIP-1; sodium-hydrogen exchanger regulatory factor 2; sodium/hydrogen exchanger; solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulator 2; solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2; solute carrier family 9 isoform 3 regulator 2; solute carrier family 9 isoform A3 regulatory factor 2; solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2; SRY-interacting protein 1; TKA-1; tyrosine kinase activator protein 1
Orthologs:
Homo sapiens (human) : SLC9A3R2 (SLC9A3 regulator 2)  HGNC
Mus musculus (house mouse) : Slc9a3r2 (solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2)  MGI
Chinchilla lanigera (long-tailed chinchilla) : Slc9a3r2 (SLC9A3 regulator 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC9A3R2 (SLC9A3 regulator 2)
Canis lupus familiaris (dog) : SLC9A3R2 (SLC9A3 regulator 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc9a3r2 (SLC9A3 regulator 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01014,003,330 - 14,015,066 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01013,820,310 - 13,830,824 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.41013,890,293 - 13,900,807 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11013,891,061 - 13,900,879 (-)NCBI
Celera1013,342,543 - 13,353,058 (-)NCBI
Cytogenetic Map10q12NCBImapview
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
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RGD Object Information
RGD ID: 620380
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2017-09-05
Status: ACTIVE