Gene: Ren (renin) Rattus norvegicus
Symbol: Ren
Name: renin
Description: ENCODES a protein that exhibits endopeptidase activity; insulin-like growth factor receptor binding; receptor binding; INVOLVED IN angiotensin maturation; beta-amyloid metabolic process; cellular response to drug; PARTICIPATES IN renin-angiotensin cascade pathway; benazepril pharmacodynamics pathway; candesartan pharmacodynamics pathway; ASSOCIATED WITH increased systemic arterial blood pressure; ASSOCIATED WITH Diabetic Nephropathies; Hypertension; Hypertrophy, Left Ventricular; FOUND IN cytoplasm; extracellular space; intracellular (ortholog); INTERACTS WITH 11-deoxycorticosterone; 2,4-dinitrotoluene; 2,6-dinitrotoluene
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: angiotensinogenase; RATRENAA; Ren1; RENAA; renin 1; renin 1 structural
Orthologs:
Homo sapiens : REN (renin)  HGNC
Mus musculus : Ren1 (renin 1 structural)  MGI
more info ...
Allele / Splice: Renem1Mcwi  
Is Marker For: Strains:   SHR.BN-(D13Arb5-Ren1)/Ipcv   SS.BN-(D13Rat20-D13Rat127)/Mcwi   SS.BN-(D13Rat123-D13Rat101)/Mcwi  
QTLs:   Bp24   Bp5  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01350,502,724 - 50,513,953 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01355,555,583 - 55,566,812 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.41346,262,936 - 46,275,213 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11346,277,000 - 46,288,249 (+)NCBI
Celera1345,129,122 - 45,139,889 (+)NCBI
Cytogenetic Map13q13NCBImapview
RH 3.4 Map13170.9RGD
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Protein Structures
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Ren
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 3554
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2016-07-05
Status: ACTIVE