Dab1 (DAB adaptor protein 1) - Rat Genome Database

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Gene: Dab1 (DAB adaptor protein 1) Rattus norvegicus
Analyze
Symbol: Dab1
Name: DAB adaptor protein 1
RGD ID: 628770
Description: Enables phosphatidylinositol 3-kinase binding activity. Involved in midgut development; nervous system development; and response to xenobiotic stimulus. Located in apical part of cell; brush border; and neuronal cell body. Biomarker of status epilepticus. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 37. Orthologous to human DAB1 (DAB adaptor protein 1); PARTICIPATES IN Reelin signaling pathway; altered Reelin signaling pathway; INTERACTS WITH (+)-schisandrin B; (R)-lipoic acid; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Dab, reelin signal transducer, homolog 1; Dab, reelin signal transducer, homolog 1 (Drosophila); DAB1, reelin adaptor protein; disabled homolog 1; disabled homolog 1 (Drosophila)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85123,621,510 - 124,742,585 (+)NCBIGRCr8
mRatBN7.25118,392,953 - 119,513,625 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5119,140,533 - 119,510,552 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5121,882,004 - 122,125,393 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05123,607,351 - 123,850,757 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05123,658,616 - 123,902,018 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05123,154,360 - 124,279,170 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5123,905,166 - 124,280,115 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05127,556,774 - 128,138,158 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45125,434,133 - 125,694,562 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15125,561,613 - 125,699,788 (+)NCBI
Celera5117,815,877 - 118,058,354 (+)NCBICelera
Cytogenetic Map5q33-q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(R)-lipoic acid  (EXP)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
beta-hexachlorocyclohexane  (ISO)
bisphenol A  (EXP,ISO)
calciol  (ISO)
CGP 52608  (ISO)
chromium(6+)  (ISO)
clozapine  (EXP)
crocidolite asbestos  (ISO)
Cuprizon  (EXP)
decabromodiphenyl ether  (EXP)
dibutyl phthalate  (ISO)
dichloroacetic acid  (ISO)
dimethylarsinic acid  (ISO)
dorsomorphin  (ISO)
endosulfan  (EXP,ISO)
ethanol  (ISO)
fluoxetine  (EXP)
folic acid  (ISO)
fonofos  (ISO)
fulvestrant  (ISO)
furan  (EXP)
glyphosate  (EXP)
indole-3-methanol  (EXP)
lipoic acid  (EXP)
maneb  (ISO)
mercury atom  (ISO)
mercury dibromide  (ISO)
mercury(0)  (ISO)
methapyrilene  (ISO)
methylarsonic acid  (ISO)
N-nitrosodiethylamine  (ISO)
nickel sulfate  (ISO)
nitric oxide  (ISO)
O-methyleugenol  (ISO)
olanzapine  (EXP)
ozone  (ISO)
p-chloromercuribenzoic acid  (ISO)
panobinostat  (ISO)
paracetamol  (ISO)
paraquat  (ISO)
parathion  (ISO)
PCB138  (ISO)
pentanal  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
poly(I:C)  (EXP)
progesterone  (ISO)
resveratrol  (ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (ISO)
SB 431542  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (EXP)
sunitinib  (ISO)
terbufos  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
triphenyl phosphate  (EXP)
troglitazone  (EXP)
valproic acid  (EXP,ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Thyroid hormone regulates reelin and dab1 expression during brain development. Alvarez-Dolado M, etal., J Neurosci 1999 Aug 15;19(16):6979-93.
2. Modulation of synaptic plasticity and memory by Reelin involves differential splicing of the lipoprotein receptor Apoer2. Beffert U, etal., Neuron. 2005 Aug 18;47(4):567-79.
3. Phosphatidylinositol 3-kinase interacts with the adaptor protein Dab1 in response to Reelin signaling and is required for normal cortical lamination. Bock HH, etal., J Biol Chem 2003 Oct 3;278(40):38772-9. Epub 2003 Jul 25.
4. Reelin signaling is impaired in autism. Fatemi SH, etal., Biol Psychiatry. 2005 Apr 1;57(7):777-87.
5. Chronic psychotropic drug treatment causes differential expression of Reelin signaling system in frontal cortex of rats. Fatemi SH, etal., Schizophr Res. 2009 Jun;111(1-3):138-52. Epub 2009 Apr 9.
6. Rat small intestine expresses the reelin-Disabled-1 signalling pathway. Garcia-Miranda P, etal., Exp Physiol. 2010 Apr;95(4):498-507. Epub 2009 Nov 27.
7. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
8. Reelin regulates neuronal progenitor migration in intact and epileptic hippocampus. Gong C, etal., J Neurosci. 2007 Feb 21;27(8):1803-11.
9. AII amacrine cells in the mammalian retina show disabled-1 immunoreactivity. Lee EJ, etal., J Comp Neurol 2004 Mar 15;470(4):372-81.
10. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
11. Maternal Thyroid Hormone before the Onset of Fetal Thyroid Function Regulates Reelin and Downstream Signaling Cascade Affecting Neocortical Neuronal Migration. Pathak A, etal., Cereb Cortex. 2010 Apr 5.
12. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
13. GOA pipeline RGD automated data pipeline
14. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
15. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
16. Rat neurological disease creeping is caused by a mutation in the reelin gene. Yokoi N, etal., Brain Res Mol Brain Res 2003 Apr 10;112(1-2):1-7.
17. A critical function for beta-amyloid precursor protein in neuronal migration revealed by in utero RNA interference. Young-Pearse TL, etal., J Neurosci. 2007 Dec 26;27(52):14459-69.
Additional References at PubMed
PMID:8875886   PMID:9338785   PMID:11226314   PMID:11812785   PMID:12526740   PMID:14578885   PMID:14715136   PMID:15062102   PMID:15091337   PMID:15249135   PMID:15632144   PMID:15703280  
PMID:18076569   PMID:18089558   PMID:18477607   PMID:18848628   PMID:20711475   PMID:21111240   PMID:24210661   PMID:28385118   PMID:28676854   PMID:29470947  


Genomics

Comparative Map Data
Dab1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85123,621,510 - 124,742,585 (+)NCBIGRCr8
mRatBN7.25118,392,953 - 119,513,625 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5119,140,533 - 119,510,552 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5121,882,004 - 122,125,393 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05123,607,351 - 123,850,757 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05123,658,616 - 123,902,018 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05123,154,360 - 124,279,170 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5123,905,166 - 124,280,115 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05127,556,774 - 128,138,158 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45125,434,133 - 125,694,562 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15125,561,613 - 125,699,788 (+)NCBI
Celera5117,815,877 - 118,058,354 (+)NCBICelera
Cytogenetic Map5q33-q34NCBI
DAB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38156,994,778 - 58,546,726 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl156,994,778 - 58,546,734 (-)EnsemblGRCh38hg38GRCh38
GRCh37157,460,451 - 59,012,398 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36157,236,167 - 58,488,799 (-)NCBINCBI36Build 36hg18NCBI36
Build 34157,175,599 - 58,428,232NCBI
Celera155,748,375 - 57,001,233 (-)NCBICelera
Cytogenetic Map1p32.2-p32.1NCBI
HuRef155,576,284 - 56,827,706 (-)NCBIHuRef
CHM1_1157,578,781 - 58,831,599 (-)NCBICHM1_1
T2T-CHM13v2.0156,873,660 - 58,424,702 (-)NCBIT2T-CHM13v2.0
Dab1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394103,476,425 - 104,602,041 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4103,476,556 - 104,602,041 (+)EnsemblGRCm39 Ensembl
GRCm384103,619,500 - 104,744,844 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4103,619,359 - 104,744,844 (+)EnsemblGRCm38mm10GRCm38
MGSCv374104,040,165 - 104,417,447 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364103,865,492 - 104,242,774 (+)NCBIMGSCv36mm8
Celera4102,719,332 - 103,096,887 (+)NCBICelera
Cytogenetic Map4C6NCBI
cM Map447.79NCBI
Dab1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554642,455,346 - 2,724,358 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554642,325,529 - 2,721,497 (+)NCBIChiLan1.0ChiLan1.0
DAB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21168,580,481 - 169,831,254 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11167,732,750 - 168,983,556 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0156,279,089 - 57,529,881 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1157,989,170 - 59,234,011 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl158,005,136 - 58,286,708 (-)Ensemblpanpan1.1panPan2
DAB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1551,397,837 - 52,505,513 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl552,231,141 - 52,502,336 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha551,546,981 - 52,573,591 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0551,664,284 - 52,692,665 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl552,292,554 - 52,692,393 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1551,611,450 - 52,637,258 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0551,557,176 - 52,583,342 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0551,840,806 - 52,867,875 (+)NCBIUU_Cfam_GSD_1.0
Dab1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505870,800,538 - 71,917,972 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365224,333,647 - 4,616,044 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365223,498,395 - 4,612,560 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DAB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6154,936,460 - 155,374,399 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16154,156,595 - 155,374,403 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26142,972,880 - 143,123,994 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DAB1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12074,727,084 - 75,968,434 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2075,541,508 - 75,968,427 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603341,328,263 - 42,605,152 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dab1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248622,892,851 - 3,144,194 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248622,053,637 - 3,159,712 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Dab1
6351 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:109
Count of miRNA genes:87
Interacting mature miRNAs:88
Transcripts:ENSRNOT00000009977
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331796Thshl2Thyroid stimulating hormone level QTL 22.3blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)597059760147465714Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5111416838156416838Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51131345958Rat
1298070Scl18Serum cholesterol level QTL 183.7blood LDL cholesterol amount (VT:0000181)calculated plasma low density lipoprotein cholesterol level (CMO:0001245)579584860124584860Rat
7794739Bp372Blood pressure QTL 3720.0058arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5117913688125222967Rat
61452Ciaa5CIA Autoantibody QTL 53.5blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)594858972143070159Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)543726656129132602Rat
1582230Bw78Body weight QTL 783.20.0016epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)5119085612128034027Rat
7411582Foco3Food consumption QTL 37.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)587468046132468046Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)560293434161481680Rat
1598859Cm66Cardiac mass QTL 662heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)579584860124584860Rat
7207486Bss109Bone structure and strength QTL 109femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)5106906205151906205Rat
7207481Bss106Bone structure and strength QTL 1067.9femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5106906205151906205Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)582394392166664054Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)546711509161317411Rat
1549838Bss4Bone structure and strength QTL 49.2femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)5106906205151906205Rat
2317753Glom24Glomerulus QTL 243.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)597570330136479578Rat
1582212Livw2Liver weight QTL 23.50.0004liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)599016066119085810Rat
7411564Bw135Body weight QTL 1350.001body mass (VT:0001259)body weight gain (CMO:0000420)587468046132468046Rat
8657050Bw146Body weight QTL 14619.840.001body mass (VT:0001259)body weight gain (CMO:0000420)5108938288153938288Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)550328551141643988Rat
7411601Foco12Food consumption QTL 1219.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)587468046132468046Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)535189153141643988Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
2317056Wbc3White blood cell count QTL 32.510.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)5105999803150999803Rat
1598846Bp293Blood pressure QTL 2933.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)579584860124584860Rat
1598847Cm62Cardiac mass QTL 623.4heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5108845856153845856Rat
1358909Kidm25Kidney mass QTL 251.87kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)590067849128034027Rat
1578673Bmd13Bone mineral density QTL 134.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)5103689353148689353Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555805606132207589Rat
7207488Bss110Bone structure and strength QTL 18.4femur strength trait (VT:0010010)femur stiffness (CMO:0001674)5106906205151906205Rat
8694441Bw169Body weight QTL 16917.610.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)5111416838156416838Rat
631527Tls1T-lymphoma susceptibility QTL 100.001thymus integrity trait (VT:0010555)post-insult time to onset of T-cell lymphoma (CMO:0001907)590450144135450144Rat
7207491Bss112Bone structure and strength QTL 1127femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)5106906205151906205Rat
8694389Bw160Body weight QTL 1606.170.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)5111416838156416838Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)531663789131345958Rat
61426Scl2Serum cholesterol level QTL 27.30.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)559793399143070159Rat
1354598Srn6Serum renin concentration QTL 63.8blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)569540295151018848Rat
8694198Abfw3Abdominal fat weight QTL 316.130.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)5111416838156416838Rat
1298086Bp156Blood pressure QTL 156arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)584132602129132602Rat
2306971Anxrr21Anxiety related response QTL 219.47fear/anxiety-related behavior trait (VT:1000241)number of entries into a discrete space in an experimental apparatus (CMO:0000960)566174080124160948Rat
1298089Scl14Serum cholesterol level QTL 145.80.0004blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5108845856153845856Rat
1358895Bp254Blood pressure QTL 2543.60.0003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)558829236128034027Rat
6903316Bw113Body weight QTL 11320.0103body mass (VT:0001259)body weight (CMO:0000012)587765973132765973Rat
1358889Bp261Blood pressure QTL 2612.86arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)590067849128034027Rat
1358187Emca1Estrogen-induced mammary cancer QTL 14.4mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)599216724148607142Rat

Markers in Region
D5Rat83  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25119,385,986 - 119,386,155 (+)MAPPERmRatBN7.2
Rnor_6.05124,150,665 - 124,150,833NCBIRnor6.0
Rnor_5.05128,010,597 - 128,010,765UniSTSRnor5.0
RGSC_v3.45125,563,750 - 125,563,919RGDRGSC3.4
RGSC_v3.45125,563,751 - 125,563,919UniSTSRGSC3.4
RGSC_v3.15125,568,977 - 125,569,145RGD
Celera5117,944,489 - 117,944,685UniSTS
RH 3.4 Map5461.0RGD
RH 3.4 Map5461.0UniSTS
SHRSP x BN Map564.9299UniSTS
SHRSP x BN Map564.9299RGD
FHH x ACI Map562.19RGD
Cytogenetic Map5q34UniSTS
D5Rat96  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25119,429,867 - 119,430,093 (+)MAPPERmRatBN7.2
Rnor_6.05124,194,249 - 124,194,472NCBIRnor6.0
Rnor_5.05128,054,181 - 128,054,404UniSTSRnor5.0
RGSC_v3.45125,607,191 - 125,607,445RGDRGSC3.4
RGSC_v3.45125,607,221 - 125,607,444UniSTSRGSC3.4
RGSC_v3.15125,612,417 - 125,612,671RGD
Celera5117,988,168 - 117,988,391UniSTS
SHRSP x BN Map564.9299RGD
SHRSP x BN Map564.9299UniSTS
Cytogenetic Map5q34UniSTS
D5Got247  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25119,393,552 - 119,393,734 (+)MAPPERmRatBN7.2
Rnor_6.05124,158,231 - 124,158,412NCBIRnor6.0
Rnor_5.05128,018,163 - 128,018,344UniSTSRnor5.0
RGSC_v3.45125,571,317 - 125,571,498UniSTSRGSC3.4
Celera5117,952,083 - 117,952,251UniSTS
Cytogenetic Map5q34UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 10 48 113 91 90 59 25 59 6 215 94 93 45 60 31

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001411819 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_153621 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006238494 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008763854 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017593175 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017593176 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017593177 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017593178 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017593179 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017593180 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017593181 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017593182 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039109333 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039109334 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039109335 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039109337 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039109338 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287210 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287212 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287214 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287215 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287216 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB072426 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473998 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214424 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000009977   ⟹   ENSRNOP00000009977
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5119,140,533 - 119,510,552 (+)Ensembl
Rnor_6.0 Ensembl5124,021,366 - 124,266,744 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000082021   ⟹   ENSRNOP00000071602
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5119,140,533 - 119,510,552 (+)Ensembl
Rnor_6.0 Ensembl5123,905,166 - 124,280,115 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000094730   ⟹   ENSRNOP00000089729
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5119,140,533 - 119,448,857 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000100043   ⟹   ENSRNOP00000084389
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5119,140,533 - 119,510,552 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000111283   ⟹   ENSRNOP00000077479
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5119,140,533 - 119,510,552 (+)Ensembl
RefSeq Acc Id: NM_001411819   ⟹   NP_001398748
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85124,369,504 - 124,742,584 (+)NCBI
mRatBN7.25119,140,533 - 119,513,624 (+)NCBI
RefSeq Acc Id: NM_153621   ⟹   NP_705885
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85124,369,933 - 124,742,584 (+)NCBI
mRatBN7.25119,140,962 - 119,513,624 (+)NCBI
Rnor_6.05124,021,366 - 124,266,744 (+)NCBI
Rnor_5.05127,556,774 - 128,138,158 (+)NCBI
RGSC_v3.45125,434,133 - 125,694,562 (+)RGD
Celera5117,815,877 - 118,058,354 (+)RGD
Sequence:
RefSeq Acc Id: XM_017593175   ⟹   XP_017448664
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85123,621,513 - 124,739,484 (+)NCBI
mRatBN7.25118,392,953 - 119,513,625 (+)NCBI
Rnor_6.05123,154,360 - 124,279,170 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017593176   ⟹   XP_017448665
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85124,369,938 - 124,739,484 (+)NCBI
mRatBN7.25119,140,955 - 119,513,625 (+)NCBI
Rnor_6.05123,905,015 - 124,279,170 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017593177   ⟹   XP_017448666
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85123,621,513 - 124,739,484 (+)NCBI
mRatBN7.25118,392,953 - 119,513,625 (+)NCBI
Rnor_6.05123,154,360 - 124,279,170 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017593178   ⟹   XP_017448667
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85124,369,707 - 124,739,484 (+)NCBI
mRatBN7.25119,140,485 - 119,513,625 (+)NCBI
Rnor_6.05123,901,769 - 124,279,170 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039109333   ⟹   XP_038965261
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85123,621,510 - 124,742,585 (+)NCBI
mRatBN7.25118,392,953 - 119,513,625 (+)NCBI
RefSeq Acc Id: XM_039109334   ⟹   XP_038965262
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85123,621,525 - 124,739,484 (+)NCBI
mRatBN7.25118,392,953 - 119,513,625 (+)NCBI
RefSeq Acc Id: XM_039109335   ⟹   XP_038965263
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85123,621,511 - 124,739,484 (+)NCBI
mRatBN7.25118,392,953 - 119,513,625 (+)NCBI
RefSeq Acc Id: XM_039109337   ⟹   XP_038965265
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85123,621,521 - 124,739,484 (+)NCBI
mRatBN7.25118,392,953 - 119,513,625 (+)NCBI
RefSeq Acc Id: XM_039109338   ⟹   XP_038965266
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85123,621,545 - 124,677,802 (+)NCBI
mRatBN7.25118,392,953 - 119,448,848 (+)NCBI
RefSeq Acc Id: XM_063287210   ⟹   XP_063143280
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85124,369,938 - 124,739,484 (+)NCBI
RefSeq Acc Id: XM_063287212   ⟹   XP_063143282
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85123,621,522 - 124,742,585 (+)NCBI
RefSeq Acc Id: XM_063287213   ⟹   XP_063143283
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85124,369,938 - 124,742,585 (+)NCBI
RefSeq Acc Id: XM_063287214   ⟹   XP_063143284
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85124,369,938 - 124,742,585 (+)NCBI
RefSeq Acc Id: XM_063287215   ⟹   XP_063143285
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85124,369,938 - 124,677,802 (+)NCBI
RefSeq Acc Id: XM_063287216   ⟹   XP_063143286
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85124,369,707 - 124,677,802 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001398748 (Get FASTA)   NCBI Sequence Viewer  
  NP_705885 (Get FASTA)   NCBI Sequence Viewer  
  XP_017448664 (Get FASTA)   NCBI Sequence Viewer  
  XP_017448665 (Get FASTA)   NCBI Sequence Viewer  
  XP_017448666 (Get FASTA)   NCBI Sequence Viewer  
  XP_017448667 (Get FASTA)   NCBI Sequence Viewer  
  XP_038965261 (Get FASTA)   NCBI Sequence Viewer  
  XP_038965262 (Get FASTA)   NCBI Sequence Viewer  
  XP_038965263 (Get FASTA)   NCBI Sequence Viewer  
  XP_038965265 (Get FASTA)   NCBI Sequence Viewer  
  XP_038965266 (Get FASTA)   NCBI Sequence Viewer  
  XP_063143280 (Get FASTA)   NCBI Sequence Viewer  
  XP_063143282 (Get FASTA)   NCBI Sequence Viewer  
  XP_063143283 (Get FASTA)   NCBI Sequence Viewer  
  XP_063143284 (Get FASTA)   NCBI Sequence Viewer  
  XP_063143285 (Get FASTA)   NCBI Sequence Viewer  
  XP_063143286 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein BAC20288 (Get FASTA)   NCBI Sequence Viewer  
  EDL97874 (Get FASTA)   NCBI Sequence Viewer  
  EDL97875 (Get FASTA)   NCBI Sequence Viewer  
  EDL97876 (Get FASTA)   NCBI Sequence Viewer  
  EDL97877 (Get FASTA)   NCBI Sequence Viewer  
  EDL97878 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000009977.1
  ENSRNOP00000071602.2
  ENSRNOP00000077479.1
  ENSRNOP00000084389.1
  ENSRNOP00000089729.1
  ENSRNOP00055009351
  ENSRNOP00060026111
  ENSRNOP00065030660
GenBank Protein Q8CJH2 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_705885   ⟸   NM_153621
- UniProtKB: Q8CJH2 (UniProtKB/Swiss-Prot),   A6JRT3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017448664   ⟸   XM_017593175
- Peptide Label: isoform X1
- UniProtKB: A0A8I5YBU9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017448666   ⟸   XM_017593177
- Peptide Label: isoform X1
- UniProtKB: A0A8I5YBU9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017448667   ⟸   XM_017593178
- Peptide Label: isoform X1
- UniProtKB: A0A8I5YBU9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017448665   ⟸   XM_017593176
- Peptide Label: isoform X1
- UniProtKB: A0A8I5YBU9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000071602   ⟸   ENSRNOT00000082021
Ensembl Acc Id: ENSRNOP00000009977   ⟸   ENSRNOT00000009977
RefSeq Acc Id: XP_038965261   ⟸   XM_039109333
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038965262   ⟸   XM_039109334
- Peptide Label: isoform X3
- UniProtKB: Q8CJH2 (UniProtKB/Swiss-Prot),   A6JRT3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038965263   ⟸   XM_039109335
- Peptide Label: isoform X4
- UniProtKB: A0A0G2K0W1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038965265   ⟸   XM_039109337
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038965266   ⟸   XM_039109338
- Peptide Label: isoform X8
- UniProtKB: A0A8I6AAY7 (UniProtKB/TrEMBL),   A6JRT5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000077479   ⟸   ENSRNOT00000111283
Ensembl Acc Id: ENSRNOP00000089729   ⟸   ENSRNOT00000094730
Ensembl Acc Id: ENSRNOP00000084389   ⟸   ENSRNOT00000100043
RefSeq Acc Id: NP_001398748   ⟸   NM_001411819
- UniProtKB: Q8CJH2 (UniProtKB/Swiss-Prot),   A6JRT3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063143282   ⟸   XM_063287212
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063143286   ⟸   XM_063287216
- Peptide Label: isoform X8
- UniProtKB: A0A8I6AAY7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063143283   ⟸   XM_063287213
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063143284   ⟸   XM_063287214
- Peptide Label: isoform X6
- UniProtKB: A0A8I6GBS3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063143280   ⟸   XM_063287210
- Peptide Label: isoform X4
- UniProtKB: A0A0G2K0W1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063143285   ⟸   XM_063287215
- Peptide Label: isoform X8
- UniProtKB: A0A8I6AAY7 (UniProtKB/TrEMBL)
Protein Domains
PID

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8CJH2-F1-model_v2 AlphaFold Q8CJH2 1-555 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693875
Promoter ID:EPDNEW_R4394
Type:single initiation site
Name:Dab1_1
Description:DAB1, reelin adaptor protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05123,905,075 - 123,905,135EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:628770 AgrOrtholog
BioCyc Gene G2FUF-40502 BioCyc
Ensembl Genes ENSRNOG00000007410 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055007126 UniProtKB/Swiss-Prot
  ENSRNOG00060018596 UniProtKB/Swiss-Prot
  ENSRNOG00065022215 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000009977.3 UniProtKB/Swiss-Prot
  ENSRNOT00000082021.2 UniProtKB/TrEMBL
  ENSRNOT00000094730.1 UniProtKB/TrEMBL
  ENSRNOT00000100043.1 UniProtKB/TrEMBL
  ENSRNOT00000111283.1 UniProtKB/TrEMBL
  ENSRNOT00055011840 UniProtKB/Swiss-Prot
  ENSRNOT00060032094 UniProtKB/Swiss-Prot
  ENSRNOT00065037902 UniProtKB/Swiss-Prot
Gene3D-CATH 2.30.29.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro DAB1/2_SBM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dab_PTB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTB/PI_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:266729 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 266729 ENTREZGENE
PANTHER DISABLED HOMOLOG 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PID DOMAIN-CONTAINING PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam DAB2_SBM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PID UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Dab1 PhenoGen
PROSITE PID UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000007410 RatGTEx
  ENSRNOG00055007126 RatGTEx
  ENSRNOG00060018596 RatGTEx
  ENSRNOG00065022215 RatGTEx
SMART PTB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2K0W1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5YBU9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AAY7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GBS3 ENTREZGENE, UniProtKB/TrEMBL
  A6JRT3 ENTREZGENE, UniProtKB/TrEMBL
  A6JRT4_RAT UniProtKB/TrEMBL
  A6JRT5 ENTREZGENE, UniProtKB/TrEMBL
  A6JRT6_RAT UniProtKB/TrEMBL
  DAB1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-10 Dab1  DAB adaptor protein 1  Dab1  DAB1, reelin adaptor protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-03-29 Dab1  DAB1, reelin adaptor protein  Dab1  Dab, reelin signal transducer, homolog 1 (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-03-20 Dab1  Dab, reelin signal transducer, homolog 1 (Drosophila)  Dab1  disabled homolog 1 (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Dab1  disabled homolog 1 (Drosophila)      Symbol and Name status set to approved 1299863 APPROVED
2003-02-27 Dab1  disabled homolog 1 (Drosophila)      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_regulation mRNA level regulated by thyroid hormone 634730
gene_regulation adaptor function stimulated by reelin 1304297