Dab1 (DAB adaptor protein 1) - Rat Genome Database

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Gene: Dab1 (DAB adaptor protein 1) Chinchilla lanigera
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Symbol: Dab1
Name: DAB adaptor protein 1
RGD ID: 8991085
Description: ENCODES a protein that exhibits phosphatidylinositol 3-kinase binding (ortholog); INVOLVED IN adult walking behavior (ortholog); astrocyte differentiation (ortholog); axonogenesis (ortholog); PARTICIPATES IN altered Reelin signaling pathway; Reelin signaling pathway; ASSOCIATED WITH autistic disorder (ortholog); Peters anomaly (ortholog); spastic ataxia (ortholog); FOUND IN apical part of cell (ortholog); brush border (ortholog); cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Dab, reelin signal transducer, homolog 1 (Drosophila); disabled homolog 1
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554642,455,346 - 2,724,358 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554642,325,529 - 2,721,497 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISS annotations to Chinchilla, Squirrel, Bonobo and/or Dog genes from Human gene annotations
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline

Genomics

Comparative Map Data
Dab1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554642,455,346 - 2,724,358 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554642,325,529 - 2,721,497 (+)NCBIChiLan1.0ChiLan1.0
DAB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38156,994,778 - 58,546,726 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl156,994,778 - 58,546,734 (-)EnsemblGRCh38hg38GRCh38
GRCh37157,460,451 - 59,012,398 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36157,236,167 - 58,488,799 (-)NCBINCBI36hg18NCBI36
Build 34157,175,599 - 58,428,232NCBI
Celera155,748,375 - 57,001,233 (-)NCBI
Cytogenetic Map1p32.2-p32.1NCBI
HuRef155,576,284 - 56,827,706 (-)NCBIHuRef
CHM1_1157,578,781 - 58,831,599 (-)NCBICHM1_1
T2T-CHM13v2.0156,873,660 - 58,424,702 (-)NCBI
Dab1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394103,476,425 - 104,602,041 (+)NCBIGRCm39mm39
GRCm39 Ensembl4103,476,556 - 104,602,041 (+)Ensembl
GRCm384103,619,500 - 104,744,844 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4103,619,359 - 104,744,844 (+)EnsemblGRCm38mm10GRCm38
MGSCv374104,040,165 - 104,417,447 (+)NCBIGRCm37mm9NCBIm37
MGSCv364103,865,492 - 104,242,774 (+)NCBImm8
Celera4102,719,332 - 103,096,887 (+)NCBICelera
Cytogenetic Map4C6NCBI
cM Map447.79NCBI
Dab1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.25118,392,953 - 119,513,625 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl5119,140,533 - 119,510,552 (+)Ensembl
Rnor_6.05123,154,360 - 124,279,170 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5123,905,166 - 124,280,115 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05127,556,774 - 128,138,158 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45125,434,133 - 125,694,562 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15125,561,613 - 125,699,788 (+)NCBI
Celera5117,815,877 - 118,058,354 (+)NCBICelera
Cytogenetic Map5q33-q34NCBI
DAB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1157,989,170 - 59,234,011 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl158,005,136 - 58,286,708 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0156,279,089 - 57,529,881 (-)NCBIMhudiblu_PPA_v0panPan3
DAB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1551,397,837 - 52,505,513 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl552,231,141 - 52,502,336 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha551,546,981 - 52,573,591 (+)NCBI
ROS_Cfam_1.0551,664,284 - 52,692,665 (+)NCBI
ROS_Cfam_1.0 Ensembl552,292,554 - 52,692,393 (+)Ensembl
UMICH_Zoey_3.1551,611,450 - 52,637,258 (+)NCBI
UNSW_CanFamBas_1.0551,557,176 - 52,583,342 (+)NCBI
UU_Cfam_GSD_1.0551,840,806 - 52,867,875 (+)NCBI
Dab1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505870,800,538 - 71,917,972 (-)NCBI
SpeTri2.0NW_0049365223,498,395 - 4,612,560 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DAB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6154,936,460 - 155,374,399 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16154,156,595 - 155,374,403 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26142,972,880 - 143,123,994 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DAB1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12074,727,084 - 75,968,434 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl2075,541,508 - 75,968,427 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603341,328,263 - 42,605,152 (-)NCBIVero_WHO_p1.0
Dab1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248622,892,851 - 3,144,194 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046248622,053,637 - 3,159,712 (+)NCBIHetGla_female_1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000009977   ⟹   ENSCLAP00000009848
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554642,455,346 - 2,724,358 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000009978   ⟹   ENSCLAP00000009849
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554642,455,346 - 2,655,847 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000009979   ⟹   ENSCLAP00000009850
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554642,587,423 - 2,655,804 (+)Ensembl
RefSeq Acc Id: XM_013521740   ⟹   XP_013377194
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554642,325,529 - 2,721,497 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013521741   ⟹   XP_013377195
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554642,325,529 - 2,721,497 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013521743   ⟹   XP_013377197
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554642,325,529 - 2,721,497 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013521744   ⟹   XP_013377198
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554642,325,529 - 2,721,497 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013521745   ⟹   XP_013377199
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554642,325,529 - 2,721,497 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_013377194   ⟸   XM_013521740
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_013377195   ⟸   XM_013521741
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_013377197   ⟸   XM_013521743
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_013377199   ⟸   XM_013521745
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_013377198   ⟸   XM_013521744
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: ENSCLAP00000009848   ⟸   ENSCLAT00000009977
RefSeq Acc Id: ENSCLAP00000009849   ⟸   ENSCLAT00000009978
RefSeq Acc Id: ENSCLAP00000009850   ⟸   ENSCLAT00000009979
Protein Domains
PID


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000006823 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCLAP00000009848 ENTREZGENE
  ENSCLAP00000009848.1 UniProtKB/TrEMBL
  ENSCLAP00000009849.1 UniProtKB/TrEMBL
  ENSCLAP00000009850.1 UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000009977 ENTREZGENE
  ENSCLAT00000009977.1 UniProtKB/TrEMBL
  ENSCLAT00000009978.1 UniProtKB/TrEMBL
  ENSCLAT00000009979.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/TrEMBL
InterPro PH-like_dom_sf UniProtKB/TrEMBL
  PTB/PI_dom UniProtKB/TrEMBL
NCBI Gene Dab1 ENTREZGENE
Pfam PID UniProtKB/TrEMBL
PROSITE PID UniProtKB/TrEMBL
SMART PTB UniProtKB/TrEMBL
UniProt A0A8C2V3R6_CHILA UniProtKB/TrEMBL
  A0A8C2V3U8_CHILA UniProtKB/TrEMBL
  A0A8C2V8V5_CHILA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-02-05 Dab1  DAB adaptor protein 1    DAB1, reelin adaptor protein  Symbol and/or name change 5135510 APPROVED
2016-08-03 Dab1  DAB1, reelin adaptor protein    Dab, reelin signal transducer, homolog 1 (Drosophila)  Symbol and/or name change 5135510 APPROVED