Syt7 (synaptotagmin 7) - Rat Genome Database

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Gene: Syt7 (synaptotagmin 7) Rattus norvegicus
Analyze
Symbol: Syt7
Name: synaptotagmin 7
RGD ID: 62013
Description: Enables several functions, including calcium ion binding activity; calcium-dependent phospholipid binding activity; and syntaxin binding activity. Involved in several processes, including calcium ion regulated lysosome exocytosis; plasma membrane repair; and regulation of vesicle-mediated transport. Located in dense core granule and lysosome. Is active in hippocampal mossy fiber to CA3 synapse and presynaptic membrane. Orthologous to human SYT7 (synaptotagmin 7); PARTICIPATES IN insulin secretion pathway; calcium/calcium-mediated signaling pathway; INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: synaptotagmin VII; synaptotagmin-7; SytVII
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: Syt7_v1 ; Syt7_v2 ; Syt7_v3
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81216,456,148 - 216,518,718 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1216,456,259 - 216,518,718 (+)EnsemblGRCr8
mRatBN7.21207,031,359 - 207,093,787 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1207,031,592 - 207,089,026 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1215,409,548 - 215,472,142 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01222,465,140 - 222,527,610 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01215,160,142 - 215,222,616 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01226,435,816 - 226,498,008 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1226,435,979 - 226,493,377 (+)Ensemblrn6Rnor6.0
Rnor_5.01233,382,523 - 233,445,604 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41212,876,675 - 212,935,373 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1204,526,212 - 204,583,576 (+)NCBICelera
RGSC_v3.11213,035,183 - 213,093,803NCBI
Cytogenetic Map1q43NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP)
17beta-estradiol 3-benzoate  (EXP)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
apomorphine  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (ISO)
beta-lapachone  (ISO)
beta-naphthoflavone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
cantharidin  (ISO)
capsaicin  (EXP)
choline  (ISO)
cisplatin  (ISO)
cobalt dichloride  (EXP)
cocaine  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
decabromodiphenyl ether  (EXP)
dexamethasone  (EXP)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
disodium selenite  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
ethanol  (ISO)
fenvalerate  (EXP)
folic acid  (ISO)
gentamycin  (EXP)
inulin  (ISO)
L-ascorbic acid  (ISO)
L-methionine  (ISO)
lead(0)  (ISO)
lipopolysaccharide  (ISO)
methimazole  (EXP)
methoxychlor  (EXP)
mono(2-ethylhexyl) phthalate  (ISO)
N,N-diethyl-m-toluamide  (EXP)
N-acetyl-L-cysteine  (EXP)
N-methyl-4-phenylpyridinium  (ISO)
O-methyleugenol  (ISO)
okadaic acid  (ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
pentanal  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
permethrin  (EXP)
propanal  (ISO)
Ptaquiloside  (ISO)
reserpine  (EXP)
resveratrol  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (EXP)
sulforaphane  (ISO)
sunitinib  (ISO)
testosterone  (EXP,ISO)
titanium dioxide  (ISO)
triclosan  (ISO)
triptonide  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
troglitazone  (ISO)
trovafloxacin  (ISO)
valproic acid  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Reduced insulin secretion correlates with decreased expression of exocytotic genes in pancreatic islets from patients with type 2 diabetes. Andersson SA, etal., Mol Cell Endocrinol. 2012 Nov 25;364(1-2):36-45. doi: 10.1016/j.mce.2012.08.009. Epub 2012 Aug 23.
2. Synaptotagmin-1 and -7 Are Redundantly Essential for Maintaining the Capacity of the Readily-Releasable Pool of Synaptic Vesicles. Bacaj T, etal., PLoS Biol. 2015 Oct 5;13(10):e1002267. doi: 10.1371/journal.pbio.1002267. eCollection 2015 Oct.
3. Alternative splicing isoforms of synaptotagmin VII in the mouse, rat and human. Fukuda M, etal., Biochem J 2002 Jul 1;365(Pt 1):173-80.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. Synaptotagmins bind calcium to release insulin. Gauthier BR and Wollheim CB, Am J Physiol Endocrinol Metab. 2008 Dec;295(6):E1279-86. Epub 2008 Aug 19.
6. Synaptotagmin VII splice variants alpha, beta, and delta are expressed in pancreatic beta-cells and regulate insulin exocytosis. Gauthier BR, etal., FASEB J. 2008 Jan;22(1):194-206. Epub 2007 Aug 20.
7. Ca(2+)-dependent and -independent activities of neural and non-neural synaptotagmins. Li C, etal., Nature 1995 Jun 15;375(6532):594-9.
8. Silence of Synaptotagmin VII inhibits release of dense core vesicles in PC12 cells. Li J, etal., Sci China C Life Sci. 2009 Dec;52(12):1156-63. doi: 10.1007/s11427-009-0160-y. Epub 2009 Dec 17.
9. Synaptotagmin VII regulates Ca(2+)-dependent exocytosis of lysosomes in fibroblasts. Martinez I, etal., J Cell Biol. 2000 Mar 20;148(6):1141-49.
10. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
11. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
12. Plasma membrane repair is mediated by Ca(2+)-regulated exocytosis of lysosomes. Reddy A, etal., Cell. 2001 Jul 27;106(2):157-69.
13. GOA pipeline RGD automated data pipeline
14. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
15. Synaptotagmin VII as a plasma membrane Ca(2+) sensor in exocytosis. Sugita S, etal., Neuron 2001 May;30(2):459-73.
16. Synaptotagmin 7 splice variants differentially regulate synaptic vesicle recycling. Virmani T, etal., EMBO J. 2003 Oct 15;22(20):5347-57. doi: 10.1093/emboj/cdg514.
17. Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins. Wilhelm BG, etal., Science. 2014 May 30;344(6187):1023-8. doi: 10.1126/science.1252884.
18. The synaptotagmins: calcium sensors for vesicular trafficking. Yoshihara M and Montana ES, Neuroscientist. 2004 Dec;10(6):566-74.
19. Release mode of large and small dense-core vesicles specified by different synaptotagmin isoforms in PC12 cells. Zhang Z, etal., Mol Biol Cell. 2011 Jul 1;22(13):2324-36. doi: 10.1091/mbc.E11-02-0159. Epub 2011 May 5.
Additional References at PubMed
PMID:10556508   PMID:12615974   PMID:12860971   PMID:12925704   PMID:14993220   PMID:15456748   PMID:16166648   PMID:16982801   PMID:18308938   PMID:18539119   PMID:19171650   PMID:20573977  
PMID:20824061   PMID:21041449   PMID:21287204   PMID:21576241   PMID:23533145   PMID:24267651   PMID:24569478   PMID:25344253   PMID:25860611   PMID:25931508   PMID:26738595   PMID:27771350  
PMID:28111077   PMID:29476059   PMID:32058590   PMID:39000085  


Genomics

Comparative Map Data
Syt7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81216,456,148 - 216,518,718 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1216,456,259 - 216,518,718 (+)EnsemblGRCr8
mRatBN7.21207,031,359 - 207,093,787 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1207,031,592 - 207,089,026 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1215,409,548 - 215,472,142 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01222,465,140 - 222,527,610 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01215,160,142 - 215,222,616 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01226,435,816 - 226,498,008 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1226,435,979 - 226,493,377 (+)Ensemblrn6Rnor6.0
Rnor_5.01233,382,523 - 233,445,604 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41212,876,675 - 212,935,373 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1204,526,212 - 204,583,576 (+)NCBICelera
RGSC_v3.11213,035,183 - 213,093,803NCBI
Cytogenetic Map1q43NCBI
SYT7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381161,513,714 - 61,588,387 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1161,513,714 - 61,581,167 (-)Ensemblhg38GRCh38
GRCh371161,281,186 - 61,348,548 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361161,039,361 - 61,104,874 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341161,039,361 - 61,104,874NCBI
Celera1158,618,148 - 58,683,697 (-)NCBICelera
Cytogenetic Map11q12.2NCBI
HuRef1157,608,716 - 57,651,861 (-)NCBIHuRef
CHM1_11161,164,220 - 61,231,379 (-)NCBICHM1_1
T2T-CHM13v2.01161,502,594 - 61,577,283 (-)NCBIT2T-CHM13v2.0
Syt7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391910,366,142 - 10,430,545 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1910,366,454 - 10,430,544 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381910,388,802 - 10,453,181 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1910,389,090 - 10,453,180 (+)Ensemblmm10GRCm38
MGSCv371910,463,580 - 10,527,671 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361910,456,528 - 10,515,489 (+)NCBIMGSCv36mm8
Celera1911,085,012 - 11,149,518 (+)NCBICelera
Cytogenetic Map19ANCBI
cM Map196.58NCBI
Syt7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555116,051,386 - 6,093,651 (+)Ensembl
ChiLan1.0NW_0049555116,051,392 - 6,093,651 (+)NCBIChiLan1.0ChiLan1.0
SYT7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2962,683,382 - 62,749,126 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11163,727,088 - 63,792,718 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01156,814,694 - 56,880,439 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11160,175,403 - 60,242,375 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1160,175,403 - 60,242,375 (-)EnsemblpanPan2panpan1.1
SYT7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11854,863,072 - 54,926,121 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1854,861,754 - 54,921,367 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1853,437,734 - 53,500,698 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01855,910,339 - 55,973,524 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1855,834,857 - 55,971,881 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11854,970,585 - 55,033,491 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01854,590,887 - 54,654,036 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01855,472,658 - 55,535,641 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Syt7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494711,385,101 - 11,444,169 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365811,512,855 - 1,559,679 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365811,516,199 - 1,557,992 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SYT7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl29,947,925 - 10,012,496 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.129,947,962 - 10,012,713 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.229,513,096 - 9,563,737 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SYT7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1112,267,591 - 12,333,181 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl112,267,685 - 12,333,185 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666038109,644,397 - 109,709,429 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Syt7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624926722,224 - 765,033 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624926722,201 - 765,834 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Syt7
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v129,862,079 - 9,925,027 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Syt7
206 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:862
Count of miRNA genes:158
Interacting mature miRNAs:185
Transcripts:ENSRNOT00000007429, ENSRNOT00000035576, ENSRNOT00000036168, ENSRNOT00000036180, ENSRNOT00000036232, ENSRNOT00000036283, ENSRNOT00000047964, ENSRNOT00000048704
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1160111531262090437Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1160573753266453731Rat
1357335Bw39Body weight QTL 393.3body mass (VT:0001259)body weight (CMO:0000012)1207243873252243873Rat
2293674Bss39Bone structure and strength QTL 397.10.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)1210980612255980612Rat
1354652Kidm20Kidney mass QTL 204.3kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1186658830266453731Rat
1354653Despr9Despair related QTL 90.00019locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1177339686222339686Rat
2293673Bss27Bone structure and strength QTL 2718.630.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)1181059071226059071Rat
2293677Bss41Bone structure and strength QTL 419.380.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)1181059071226059071Rat
1549830Bss1Bone structure and strength QTL 14.8femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)1182039247227039247Rat
70163Bw20Body weight QTL 205.1body mass (VT:0001259)body weight (CMO:0000012)1183564652228564652Rat
1600395Niddm69Non-insulin dependent diabetes mellitus QTL 694.140.0002blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1205233991267096252Rat
1600396Niddm68Non-insulin dependent diabetes mellitus QTL 684.970.0003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1205233991267096252Rat
1354624Cm35Cardiac mass QTL355.7heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1186658830266453731Rat
1600397Edcs4Endometrial carcinoma susceptibility QTL 42.2uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)1176288899270518180Rat
631838Niddm36Non-insulin dependent diabetes mellitus QTL 360.01insulin secretion trait (VT:0003564)calculated pancreatic islet insulin release measurement (CMO:0001217)1193964073238964073Rat
1549837Hcar15Hepatocarcinoma resistance QTL 150.05liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1162548015270518180Rat
2293689Bss47Bone structure and strength QTL 477.250.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)1181059071226059071Rat
2293694Bss38Bone structure and strength QTL 387.050.0001femur strength trait (VT:0010010)femur stiffness (CMO:0001674)1210980612255980612Rat
1600388Niddm67Non-insulin dependent diabetes mellitus QTL 675.840.000004blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1205233991267096252Rat
152025235Bw194Body weight QTL 1944.86body mass (VT:0001259)1132966869252856240Rat
1598853Memor3Memory QTL 34.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)1152919152268496042Rat
61341Bp26Blood pressure QTL 26arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1139442053223964440Rat
2293693Bss22Bone structure and strength QTL 2233.520.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1181059071226059071Rat
1578759Uae30Urinary albumin excretion QTL 303.30.003urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1160111531262090437Rat
2300161Bmd43Bone mineral density QTL 438.40.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1181059071226059071Rat
1300145Rf7Renal function QTL 72.96urine creatinine amount (VT:0010540)urine creatinine level (CMO:0000125)1194575422239575422Rat
1358902Bw47Body weight QTL 471.67body mass (VT:0001259)body weight (CMO:0000012)199645382221502378Rat
8655655Arrd2Age-related retinal degeneration QTL 27.79retinal layer morphology trait (VT:0003727)percentage of study population developing retinopathy during a period of time (CMO:0002453)1193400541238400541Rat
1358898Bp255Blood pressure QTL 2553.6arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1200449456256003563Rat
631214Bw61Body weight QTL613.40.0001intramuscular adipose amount (VT:0010044)intramuscular fat area (CMO:0001162)1182535316227535316Rat
7771612Cm80Cardiac mass QTL 808.4heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)1146080545243492863Rat
731168Bp154Blood pressure QTL 1543.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1103779152223964440Rat
731175Uae20Urinary albumin excretion QTL 203.50.0018urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1207163993269633915Rat
2300175Bmd40Bone mineral density QTL 4015.40.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)1210980612255980612Rat
2300174Bmd42Bone mineral density QTL 428.40.0001lumbar vertebra mineral mass (VT:0010511)bone mineral density (CMO:0001226)1181059071226059071Rat
737828Hcas3Hepatocarcinoma susceptibility QTL 34.9liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)1153679879232414077Rat
1354661Bw33Body weight QTL 335.2body mass (VT:0001259)body weight (CMO:0000012)1160573753266453731Rat
1358886Bp260Blood pressure QTL 2603.67arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1160574007235238518Rat
2293654Bss30Bone structure and strength QTL 3032.650.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1181059071226059071Rat
2293655Bss36Bone structure and strength QTL 3610.660.0001femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)1210980612255980612Rat
1298084Thym4Thymus enlargement QTL 410.68thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)1207243873252243873Rat
724531Uae5Urinary albumin excretion QTL 54urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)1160111426262090599Rat
2300187Bmd41Bone mineral density QTL 418.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1181059071226059071Rat
2314011Gluco56Glucose level QTL 56blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1209203273254203273Rat
8552891Epfw5Epididymal fat weight QTL 54.4epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1202543537247543537Rat
1354580Scort1Serum corticosterone level QTL 13.4blood corticosterone amount (VT:0005345)blood corticosterone level (CMO:0001172)1154961463266453731Rat
634313Niddm43Non-insulin dependent diabetes mellitus QTL 43blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1208479811269633915Rat
1358292Cm37Cardiac mass QTL 376.28e-07heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)1205674651250674651Rat
61376Bp42Blood pressure QTL 4223.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1207243873252243873Rat
634312Bp143Blood pressure QTL 14330.0002arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1203300512229359342Rat
1358294Bw37Body weight QTL 3750.000011body mass (VT:0001259)body weight (CMO:0000012)1180739993225739993Rat
724559Pancm1Pancreatic morphology QTL 17.1islet of Langerhans morphology trait (VT:0005215)pancreatic islet damage composite score (CMO:0001156)1191190115223964326Rat
2312420Pur17Proteinuria QTL 177.10.0001urine protein amount (VT:0005160)urine total protein excretion rate (CMO:0000756)1172718770228180370Rat
10059600Bp378Blood pressure QTL 3783.080.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1186298393231298393Rat
1358916Kidm22Kidney mass QTL 223.32kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1212738576257738576Rat
2312564Glom18Glomerulus QTL 182.40.003kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)1194786607262083703Rat
2292218Kidm35Kidney mass QTL 35kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1208798288253798288Rat
634321Hc1Hypercalciuria QTL 12.91urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1188241285250779312Rat
724562Rends1Renal damage susceptibility QTL 10.05kidney glomerulus integrity trait (VT:0010546)index of glomerular damage (CMO:0001135)1139442053223964440Rat
1300168Bp170Blood pressure QTL 1702.76arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1192995199237995199Rat
61403Niddm4Non-insulin dependent diabetes mellitus QTL 4blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1201464383246464383Rat
2292222Bp307Blood pressure QTL 3073.060.0014arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1186298393231298393Rat
2292220Bp306Blood pressure QTL 3063.470.00087arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1186298393231298393Rat
1641926Teswt2Testicular weight QTL 22.82testis mass (VT:1000644)both testes wet weight (CMO:0000175)1203675682248675682Rat
631658Cm7Cardiac mass QTL 75.320.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)1205674651250674651Rat
1600380Niddm70Non-insulin dependent diabetes mellitus QTL 703.10.0008blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1185979875230979875Rat
1582206Kidm33Kidney mass QTL 336.9kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1197807365233480676Rat
2293700Bmd27Bone mineral density QTL 276.60.0001femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)1210980612255980612Rat
1354610Bw34Body weight QTL 344.1body mass (VT:0001259)body weight (CMO:0000012)1160573753266453731Rat
2293701Bmd34Bone mineral density QTL 348.30.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)1210980612255980612Rat
634338Hcar4Hepatocarcinoma resistance QTL 44.6liver integrity trait (VT:0010547)liver tumorous lesion number to liver area ratio (CMO:0001210)1202851915223964440Rat
8655855Arrd3Age-related retinal degeneration QTL 33.07lens clarity trait (VT:0001304)cataract incidence/prevalence measurement (CMO:0001585)1193400541238400541Rat
1600374Mcs17Mammary carcinoma susceptibility QTL 173mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1207099883252099883Rat
6903303Scl34Serum cholesterol QTL 342.50.0033blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)1173363824227535316Rat
1600363Hc6Hypercalciuria QTL 62.7urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1210980612255980612Rat
2293083Iddm25Insulin dependent diabetes mellitus QTL 254.18blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1191260175236260175Rat
1354606Bp246Blood pressure QTL 2463.6arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)1111949780228180370Rat
738032Hcas5Hepatocarcinoma susceptibility QTL 53.12liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1185857683270518180Rat
2325727Pia41Pristane induced arthritis QTL 41joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1188241285233241285Rat
7394701Uae46Urinary albumin excretion QTL 463.60.0056urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1210980612255980612Rat

Markers in Region
D1Rat293  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81216,461,843 - 216,462,031 (+)Marker Load Pipeline
mRatBN7.21207,036,933 - 207,037,121 (+)MAPPERmRatBN7.2
Rnor_6.01226,441,138 - 226,441,325NCBIRnor6.0
Rnor_5.01233,387,844 - 233,388,031UniSTSRnor5.0
RGSC_v3.41212,881,866 - 212,882,054RGDRGSC3.4
RGSC_v3.41212,881,867 - 212,882,054UniSTSRGSC3.4
Celera1204,531,587 - 204,531,774UniSTS
RGSC_v3.11213,040,296 - 213,040,484RGD
SHRSP x BN Map1106.05UniSTS
SHRSP x BN Map1106.05RGD
Cytogenetic Map1q43UniSTS
BE115310  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21207,048,023 - 207,048,191 (+)MAPPERmRatBN7.2
Rnor_6.01226,452,224 - 226,452,391NCBIRnor6.0
Rnor_5.01233,399,232 - 233,399,399UniSTSRnor5.0
RGSC_v3.41212,892,954 - 212,893,121UniSTSRGSC3.4
Celera1204,542,534 - 204,542,701UniSTS
RH 3.4 Map11509.89UniSTS
Cytogenetic Map1q43UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 161 91 90 59 38 59 6 300 138 11 140 79 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001398614 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001398615 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001398616 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001398617 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001398618 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001398620 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_021659 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006231066 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017589634 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017589635 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017589636 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017589637 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017589638 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088864 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088876 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272250 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC095662 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC130565 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF336852 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF336853 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF336854 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF336855 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF336856 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF336857 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF336858 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF336859 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF336860 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473953 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U20106 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y19242 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000007429   ⟹   ENSRNOP00000007429
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1216,456,259 - 216,518,718 (+)Ensembl
mRatBN7.2 Ensembl1207,031,592 - 207,088,958 (+)Ensembl
Rnor_6.0 Ensembl1226,436,139 - 226,493,179 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000035576   ⟹   ENSRNOP00000031890
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1216,456,259 - 216,518,718 (+)Ensembl
mRatBN7.2 Ensembl1207,031,592 - 207,089,026 (+)Ensembl
Rnor_6.0 Ensembl1226,436,139 - 226,493,179 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000036168   ⟹   ENSRNOP00000031944
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1216,456,259 - 216,518,718 (+)Ensembl
mRatBN7.2 Ensembl1207,031,592 - 207,089,026 (+)Ensembl
Rnor_6.0 Ensembl1226,436,139 - 226,493,179 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000036180   ⟹   ENSRNOP00000032388
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1216,456,259 - 216,518,718 (+)Ensembl
mRatBN7.2 Ensembl1207,031,592 - 207,089,026 (+)Ensembl
Rnor_6.0 Ensembl1226,436,139 - 226,493,179 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000036232   ⟹   ENSRNOP00000031195
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1216,456,259 - 216,518,718 (+)Ensembl
mRatBN7.2 Ensembl1207,031,592 - 207,089,026 (+)Ensembl
Rnor_6.0 Ensembl1226,436,090 - 226,493,377 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000036283   ⟹   ENSRNOP00000031816
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1216,456,259 - 216,518,718 (+)Ensembl
mRatBN7.2 Ensembl1207,031,592 - 207,089,026 (+)Ensembl
Rnor_6.0 Ensembl1226,436,139 - 226,493,179 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000047964   ⟹   ENSRNOP00000049360
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1216,456,259 - 216,518,718 (+)Ensembl
mRatBN7.2 Ensembl1207,031,592 - 207,089,026 (+)Ensembl
Rnor_6.0 Ensembl1226,436,139 - 226,493,179 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000048704   ⟹   ENSRNOP00000040667
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1216,456,259 - 216,518,718 (+)Ensembl
mRatBN7.2 Ensembl1207,031,592 - 207,089,026 (+)Ensembl
Rnor_6.0 Ensembl1226,435,979 - 226,493,247 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000099457   ⟹   ENSRNOP00000080801
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1207,054,052 - 207,089,026 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000099494   ⟹   ENSRNOP00000085392
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1216,456,259 - 216,518,718 (+)Ensembl
mRatBN7.2 Ensembl1207,031,592 - 207,089,026 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000172421   ⟹   ENSRNOP00000102358
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1216,483,760 - 216,518,718 (+)Ensembl
RefSeq Acc Id: NM_001398614   ⟹   NP_001385543
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81216,456,259 - 216,518,718 (+)NCBI
mRatBN7.21207,031,359 - 207,093,787 (+)NCBI
RefSeq Acc Id: NM_001398615   ⟹   NP_001385544
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81216,456,259 - 216,518,718 (+)NCBI
mRatBN7.21207,031,359 - 207,093,787 (+)NCBI
RefSeq Acc Id: NM_001398616   ⟹   NP_001385545
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81216,456,259 - 216,518,718 (+)NCBI
mRatBN7.21207,031,359 - 207,093,787 (+)NCBI
RefSeq Acc Id: NM_001398617   ⟹   NP_001385546
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81216,456,259 - 216,518,718 (+)NCBI
mRatBN7.21207,031,359 - 207,093,787 (+)NCBI
RefSeq Acc Id: NM_001398618   ⟹   NP_001385547
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81216,456,259 - 216,518,718 (+)NCBI
mRatBN7.21207,031,359 - 207,093,787 (+)NCBI
RefSeq Acc Id: NM_001398620   ⟹   NP_001385549
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81216,456,259 - 216,518,718 (+)NCBI
mRatBN7.21207,031,359 - 207,093,787 (+)NCBI
RefSeq Acc Id: NM_021659   ⟹   NP_067691
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81216,456,259 - 216,518,718 (+)NCBI
mRatBN7.21207,031,359 - 207,093,787 (+)NCBI
Rnor_6.01226,435,979 - 226,493,247 (+)NCBI
Rnor_5.01233,382,523 - 233,445,604 (+)NCBI
RGSC_v3.41212,876,675 - 212,935,373 (+)RGD
Celera1204,526,212 - 204,583,576 (+)RGD
Sequence:
RefSeq Acc Id: XM_039088864   ⟹   XP_038944792
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81216,456,151 - 216,517,083 (+)NCBI
mRatBN7.21207,031,371 - 207,093,787 (+)NCBI
RefSeq Acc Id: XM_039088876   ⟹   XP_038944804
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81216,456,156 - 216,517,083 (+)NCBI
mRatBN7.21207,031,374 - 207,093,787 (+)NCBI
RefSeq Acc Id: XM_063272250   ⟹   XP_063128320
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81216,456,148 - 216,517,083 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001385543 (Get FASTA)   NCBI Sequence Viewer  
  NP_001385544 (Get FASTA)   NCBI Sequence Viewer  
  NP_001385545 (Get FASTA)   NCBI Sequence Viewer  
  NP_001385546 (Get FASTA)   NCBI Sequence Viewer  
  NP_001385547 (Get FASTA)   NCBI Sequence Viewer  
  NP_001385549 (Get FASTA)   NCBI Sequence Viewer  
  NP_067691 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944792 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944804 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128320 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA87725 (Get FASTA)   NCBI Sequence Viewer  
  AAK01447 (Get FASTA)   NCBI Sequence Viewer  
  AAK01448 (Get FASTA)   NCBI Sequence Viewer  
  AAK01449 (Get FASTA)   NCBI Sequence Viewer  
  AAK01450 (Get FASTA)   NCBI Sequence Viewer  
  AAK01451 (Get FASTA)   NCBI Sequence Viewer  
  AAK01452 (Get FASTA)   NCBI Sequence Viewer  
  AAK01453 (Get FASTA)   NCBI Sequence Viewer  
  AAK01454 (Get FASTA)   NCBI Sequence Viewer  
  AAK01455 (Get FASTA)   NCBI Sequence Viewer  
  EDM12799 (Get FASTA)   NCBI Sequence Viewer  
  EDM12800 (Get FASTA)   NCBI Sequence Viewer  
  EDM12801 (Get FASTA)   NCBI Sequence Viewer  
  EDM12802 (Get FASTA)   NCBI Sequence Viewer  
  EDM12803 (Get FASTA)   NCBI Sequence Viewer  
  EDM12804 (Get FASTA)   NCBI Sequence Viewer  
  EDM12805 (Get FASTA)   NCBI Sequence Viewer  
  EDM12806 (Get FASTA)   NCBI Sequence Viewer  
  EDM12807 (Get FASTA)   NCBI Sequence Viewer  
  EDM12808 (Get FASTA)   NCBI Sequence Viewer  
  EDM12809 (Get FASTA)   NCBI Sequence Viewer  
  EDM12810 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000007429
  ENSRNOP00000007429.5
  ENSRNOP00000031195
  ENSRNOP00000031195.4
  ENSRNOP00000031816
  ENSRNOP00000031816.4
  ENSRNOP00000031890
  ENSRNOP00000031890.4
  ENSRNOP00000031944
  ENSRNOP00000031944.4
  ENSRNOP00000032388
  ENSRNOP00000040667
  ENSRNOP00000040667.3
  ENSRNOP00000049360
  ENSRNOP00000049360.4
  ENSRNOP00000085392
GenBank Protein Q62747 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_067691   ⟸   NM_021659
- Peptide Label: isoform 7
- UniProtKB: Q99P37 (UniProtKB/Swiss-Prot),   Q99P36 (UniProtKB/Swiss-Prot),   Q99P35 (UniProtKB/Swiss-Prot),   Q99P34 (UniProtKB/Swiss-Prot),   Q99P33 (UniProtKB/Swiss-Prot),   Q99J98 (UniProtKB/Swiss-Prot),   F1M262 (UniProtKB/Swiss-Prot),   Q99P38 (UniProtKB/Swiss-Prot),   Q62747 (UniProtKB/TrEMBL),   A6I025 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000031890   ⟸   ENSRNOT00000035576
Ensembl Acc Id: ENSRNOP00000049360   ⟸   ENSRNOT00000047964
Ensembl Acc Id: ENSRNOP00000031944   ⟸   ENSRNOT00000036168
Ensembl Acc Id: ENSRNOP00000032388   ⟸   ENSRNOT00000036180
Ensembl Acc Id: ENSRNOP00000031816   ⟸   ENSRNOT00000036283
Ensembl Acc Id: ENSRNOP00000031195   ⟸   ENSRNOT00000036232
Ensembl Acc Id: ENSRNOP00000040667   ⟸   ENSRNOT00000048704
Ensembl Acc Id: ENSRNOP00000007429   ⟸   ENSRNOT00000007429
RefSeq Acc Id: XP_038944792   ⟸   XM_039088864
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038944804   ⟸   XM_039088876
- Peptide Label: isoform X3
- UniProtKB: A0A8I6A1J0 (UniProtKB/TrEMBL),   A6I025 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000085392   ⟸   ENSRNOT00000099494
Ensembl Acc Id: ENSRNOP00000080801   ⟸   ENSRNOT00000099457
RefSeq Acc Id: NP_001385543   ⟸   NM_001398614
- Peptide Label: isoform 1
- UniProtKB: A0A8L2QJI4 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001385547   ⟸   NM_001398618
- Peptide Label: isoform 5
RefSeq Acc Id: NP_001385545   ⟸   NM_001398616
- Peptide Label: isoform 3
- UniProtKB: A0A8L2QJI4 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001385544   ⟸   NM_001398615
- Peptide Label: isoform 2
- UniProtKB: A0A8L2QJI4 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001385549   ⟸   NM_001398620
- Peptide Label: isoform 6
RefSeq Acc Id: NP_001385546   ⟸   NM_001398617
- Peptide Label: isoform 4
- UniProtKB: A0A8L2QJI4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063128320   ⟸   XM_063272250
- Peptide Label: isoform X1
- UniProtKB: A0A8L2QJI4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000102358   ⟸   ENSRNOT00000172421
Protein Domains
C2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q62747-F1-model_v2 AlphaFold Q62747 1-403 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:62013 AgrOrtholog
BIND 130904
  133976
  133977
  133978
BioCyc Gene G2FUF-56431 BioCyc
Ensembl Genes ENSRNOG00000026432 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000007429 ENTREZGENE
  ENSRNOT00000007429.9 UniProtKB/Swiss-Prot
  ENSRNOT00000035576 ENTREZGENE
  ENSRNOT00000035576.7 UniProtKB/Swiss-Prot
  ENSRNOT00000036168 ENTREZGENE
  ENSRNOT00000036168.7 UniProtKB/Swiss-Prot
  ENSRNOT00000036180 ENTREZGENE
  ENSRNOT00000036232 ENTREZGENE
  ENSRNOT00000036232.7 UniProtKB/Swiss-Prot
  ENSRNOT00000036283 ENTREZGENE
  ENSRNOT00000036283.7 UniProtKB/Swiss-Prot
  ENSRNOT00000047964 ENTREZGENE
  ENSRNOT00000047964.5 UniProtKB/Swiss-Prot
  ENSRNOT00000048704 ENTREZGENE
  ENSRNOT00000048704.6 UniProtKB/Swiss-Prot
  ENSRNOT00000099494 ENTREZGENE
Gene3D-CATH 2.60.40.150 UniProtKB/Swiss-Prot
InterPro C2_dom UniProtKB/Swiss-Prot
  C2_domain_sf UniProtKB/Swiss-Prot
  C2A_Synaptotagmin-7 UniProtKB/Swiss-Prot
  C2B_Synaptotagmin-7 UniProtKB/Swiss-Prot
  Synaptotagmin UniProtKB/Swiss-Prot
KEGG Report rno:59267 UniProtKB/Swiss-Prot
NCBI Gene 59267 ENTREZGENE
PANTHER SYNAPTOTAGMIN UniProtKB/Swiss-Prot
  SYNAPTOTAGMIN-7 UniProtKB/Swiss-Prot
Pfam PF00168 UniProtKB/Swiss-Prot
PhenoGen Syt7 PhenoGen
PRINTS C2DOMAIN UniProtKB/Swiss-Prot
  SYNAPTOTAGMN UniProtKB/Swiss-Prot
PROSITE PS50004 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000026432 RatGTEx
SMART SM00239 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF49562 UniProtKB/Swiss-Prot
UniProt A0A8I6A1J0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2QJI4 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LCM7_RAT UniProtKB/TrEMBL
  A6I025 ENTREZGENE, UniProtKB/TrEMBL
  A6I026_RAT UniProtKB/TrEMBL
  A6I028_RAT UniProtKB/TrEMBL
  A6I029_RAT UniProtKB/TrEMBL
  A6I030_RAT UniProtKB/TrEMBL
  F1M262 ENTREZGENE
  Q62747 ENTREZGENE
  Q99J98 ENTREZGENE
  Q99P33 ENTREZGENE
  Q99P34 ENTREZGENE
  Q99P35 ENTREZGENE
  Q99P36 ENTREZGENE
  Q99P37 ENTREZGENE
  Q99P38 ENTREZGENE
  SYT7_RAT UniProtKB/Swiss-Prot
UniProt Secondary F1M262 UniProtKB/Swiss-Prot
  Q99J98 UniProtKB/Swiss-Prot
  Q99P33 UniProtKB/Swiss-Prot
  Q99P34 UniProtKB/Swiss-Prot
  Q99P35 UniProtKB/Swiss-Prot
  Q99P36 UniProtKB/Swiss-Prot
  Q99P37 UniProtKB/Swiss-Prot
  Q99P38 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-01-11 Syt7  synaptotagmin 7  Syt7  synaptotagmin VII  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Syt7  synaptotagmin VII    synaptotagmin 7  Name updated 1299863 APPROVED
2002-06-10 Syt7  synaptotagmin 7      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization localized in the lysosome of fibroblasts 619692
gene_expression expressed in a regulated pattern in the brain 634203
gene_function responsible for triggering neurotransmitter release by acting as Ca(2+) sensors 634203
gene_process regulates different types of calcium dependent exocytosis 619692
gene_product member of the synaptotagmin family of C-terminal-type tandem C2 proteins 619692