Cerkl (CERK like autophagy regulator) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Cerkl (CERK like autophagy regulator) Rattus norvegicus
Analyze
Symbol: Cerkl
Name: CERK like autophagy regulator (Ensembl:ceramide kinase-like)
RGD ID: 1561057
Description: Predicted to enable sphingolipid binding activity. Predicted to be involved in negative regulation of apoptotic process. Predicted to act upstream of or within sphingolipid biosynthetic process. Predicted to be located in several cellular components, including nuclear lumen; photoreceptor inner segment; and photoreceptor outer segment. Human ortholog(s) of this gene implicated in retinitis pigmentosa and retinitis pigmentosa 26. Orthologous to human CERKL (ceramide kinase like); INTERACTS WITH fenvalerate; valproic acid; vinclozolin.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ceramide kinase-like; LOC502640; RGD1561057; similar to ceramide kinase-like
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8384,641,121 - 84,747,999 (-)NCBIGRCr8
mRatBN7.2364,238,714 - 64,344,695 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl364,237,522 - 64,340,675 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0366,268,835 - 66,395,615 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl366,268,947 - 66,394,764 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0372,830,404 - 72,955,341 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4362,103,856 - 62,204,116 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera363,698,857 - 63,800,301 (-)NCBICelera
Cytogenetic Map3q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Comprehensive gene review and curation RGD comprehensive gene curation
7. Mutation of CERKL, a novel human ceramide kinase gene, causes autosomal recessive retinitis pigmentosa (RP26). Tuson M, etal., Am J Hum Genet. 2004 Jan;74(1):128-38. Epub 2003 Dec 16.
Additional References at PubMed
PMID:18555012   PMID:19158957   PMID:19501188   PMID:21151604   PMID:23142158   PMID:23501591  


Genomics

Comparative Map Data
Cerkl
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8384,641,121 - 84,747,999 (-)NCBIGRCr8
mRatBN7.2364,238,714 - 64,344,695 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl364,237,522 - 64,340,675 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0366,268,835 - 66,395,615 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl366,268,947 - 66,394,764 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0372,830,404 - 72,955,341 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4362,103,856 - 62,204,116 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera363,698,857 - 63,800,301 (-)NCBICelera
Cytogenetic Map3q24NCBI
CERKL
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382181,536,672 - 181,657,105 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2181,535,041 - 181,680,665 (-)EnsemblGRCh38hg38GRCh38
GRCh372182,401,399 - 182,521,832 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362182,109,650 - 182,229,996 (-)NCBINCBI36Build 36hg18NCBI36
Build 342182,226,911 - 182,347,257NCBI
Celera2175,997,484 - 176,117,888 (-)NCBICelera
Cytogenetic Map2q31.3NCBI
HuRef2174,258,264 - 174,378,426 (-)NCBIHuRef
CHM1_12182,406,604 - 182,527,616 (-)NCBICHM1_1
T2T-CHM13v2.02182,026,827 - 182,147,207 (-)NCBIT2T-CHM13v2.0
Cerkl
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39279,162,835 - 79,259,332 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl279,160,887 - 79,287,129 (-)EnsemblGRCm39 Ensembl
GRCm38279,332,491 - 79,428,988 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl279,330,543 - 79,456,785 (-)EnsemblGRCm38mm10GRCm38
MGSCv37279,172,648 - 79,269,145 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36279,132,873 - 79,133,959 (+)NCBIMGSCv36mm8
Celera280,991,252 - 81,088,535 (-)NCBICelera
Cytogenetic Map2C3NCBI
cM Map247.43NCBI
Cerkl
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495540315,620,047 - 15,727,957 (+)NCBIChiLan1.0ChiLan1.0
CERKL
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21384,186,541 - 84,308,125 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B84,202,998 - 84,323,098 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B68,800,462 - 68,921,793 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B186,611,147 - 186,731,484 (-)NCBIpanpan1.1PanPan1.1panPan2
CERKL
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13624,708,109 - 24,839,240 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3624,710,035 - 24,859,028 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3624,731,428 - 24,862,131 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03624,871,001 - 25,001,556 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3624,872,357 - 25,001,556 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13624,960,221 - 25,091,171 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03624,925,686 - 25,056,169 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03625,060,795 - 25,191,691 (-)NCBIUU_Cfam_GSD_1.0
Cerkl
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303141,741,059 - 141,850,691 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650910,294,988 - 10,404,609 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493650910,294,247 - 10,404,743 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CERKL
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1587,029,306 - 87,159,566 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11587,029,237 - 87,159,555 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21596,602,544 - 96,649,976 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CERKL
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11067,055,654 - 67,185,927 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1067,056,078 - 67,185,580 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040132,389,417 - 132,524,424 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cerkl
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248443,354,823 - 3,474,036 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Cerkl
568 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:216
Count of miRNA genes:64
Interacting mature miRNAs:68
Transcripts:ENSRNOT00000043238, ENSRNOT00000057878, ENSRNOT00000073412
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1582238Bw68Body weight QTL 683.20.0064body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1582239Epfw1Epididymal fat weight QTL 14.50.0006epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)353184593115665732Rat
2298542Neuinf11Neuroinflammation QTL 113.9nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)31500542276927699Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)338192233133483320Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)329463235118376539Rat
1582218Bw74Body weight QTL 743.90.0021body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1581568Rf53Renal function QTL 53urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
9590286Uminl1Urine mineral level QTL 13.50.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)32824968773249687Rat
1300111Rf12Renal function QTL 123.78renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)361017749121056321Rat
724523Tsu1Thymus enlargement suppressive QTL 13.84thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)350437504115638231Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)359242096157323038Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)343827364121056321Rat
2292613Ept16Estrogen-induced pituitary tumorigenesis QTL 168.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat
731180Bp152Blood pressure QTL 1520.03arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)35378111291609953Rat
631200Cm25Cardiac mass QTL 254.80.0001heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)36113434889115068Rat
61356Bp37Blood pressure QTL 373blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)33068464275684642Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)31086191289878372Rat
8694196Abfw2Abdominal fat weight QTL 216.580.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)32824968773249687Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
1582249Bw77Body weight QTL 773.20.0025epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)35318459364655484Rat
2290452Scl56Serum cholesterol level QTL 562.26blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)3191609953Rat
12879868Am6Aortic mass QTL 60.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)33142640370668733Rat
11565451Bw177Body weight QTL 1770.002body mass (VT:0001259)body weight (CMO:0000012)33142640370668733Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
11565452Kidm57Kidney mass QTL 570.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)33142640370668733Rat
12879866Cm94Cardiac mass QTL 940.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)33142640370668733Rat
12879867Cm95Cardiac mass QTL 950.047heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)33142640370668733Rat
1300178Hrtrt4Heart rate QTL 43.74heart pumping trait (VT:2000009)heart rate (CMO:0000002)34382736490905114Rat
61377Edpm3Estrogen-dependent pituitary mass QTL 37.050.038pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)35318469289878207Rat
2302055Pia30Pristane induced arthritis QTL 303.50.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)32793691972936919Rat
1331795Rf30Renal function QTL 303.708urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)33945463789115240Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
1354589Bw31Body weight QTL 313.3body mass (VT:0001259)body weight (CMO:0000012)33370334778196190Rat
2303593Gluco46Glucose level QTL 463blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)32846857173468571Rat
1354590Despr11Despair related QTL 110.000031locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)32846857173468571Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
1331777Bw24Body weight QTL 243.503body mass (VT:0001259)body weight (CMO:0000012)33945463789115240Rat
631647Bp122Blood pressure QTL 1226.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)33068464275684642Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
738019Anxrr10Anxiety related response QTL 103.9exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)33851780383517803Rat
9590136Scort3Serum corticosterone level QTL 323.370.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)32824968773249687Rat
10450804Scl70Serum cholesterol level QTL 704.70.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)32071409065714090Rat
61419Cia11Collagen induced arthritis QTL 115.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)33035677398535386Rat
1354597Kidm13Kidney mass QTL 132.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)341874578104104347Rat
8552950Pigfal12Plasma insulin-like growth factor 1 level QTL 127.3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)32824968773249687Rat
10450794Scl69Serum cholesterol level QTL 696.30.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)32071409065714090Rat
8694386Bw159Body weight QTL 1594.520.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)32824968773249687Rat
1354604Bw36Body weight QTL 362.9body mass (VT:0001259)body weight (CMO:0000012)333703347104104347Rat
631665Bw8Body weight QTL 85.5body mass (VT:0001259)body weight (CMO:0000012)350437042119183768Rat
2301400Cm68Cardiac mass QTL 680.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)33142640370668733Rat
1358186Ept2Estrogen-induced pituitary tumorigenesis QTL 28.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat

Markers in Region
RH130584  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2364,239,083 - 64,239,269 (+)MAPPERmRatBN7.2
Rnor_6.0366,269,296 - 66,269,481NCBIRnor6.0
Rnor_5.0372,830,803 - 72,830,988UniSTSRnor5.0
RGSC_v3.4362,103,247 - 62,103,432UniSTSRGSC3.4
Celera363,699,318 - 63,699,503UniSTS
Cytogenetic Map3q24UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 10 33 113 51 50 19 25 19 6 157 79 93 42 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000043238   ⟹   ENSRNOP00000045933
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl366,268,994 - 66,335,869 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000057878   ⟹   ENSRNOP00000054687
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl364,237,522 - 64,340,675 (-)Ensembl
Rnor_6.0 Ensembl366,268,994 - 66,335,869 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000073412   ⟹   ENSRNOP00000067516
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl366,268,994 - 66,335,869 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000075832   ⟹   ENSRNOP00000064891
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl364,237,522 - 64,340,675 (-)Ensembl
Rnor_6.0 Ensembl366,268,947 - 66,394,764 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000079212   ⟹   ENSRNOP00000068874
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl366,268,994 - 66,335,869 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000079781   ⟹   ENSRNOP00000070865
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl366,268,994 - 66,335,869 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000079887   ⟹   ENSRNOP00000068848
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl366,274,627 - 66,279,155 (-)Ensembl
RefSeq Acc Id: XM_056985384   ⟹   XP_056841364
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8384,641,121 - 84,747,968 (-)NCBI
mRatBN7.2364,238,714 - 64,344,688 (-)NCBI
RefSeq Acc Id: XM_056985385   ⟹   XP_056841365
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8384,646,621 - 84,747,999 (-)NCBI
mRatBN7.2364,239,702 - 64,344,695 (-)NCBI
Protein Sequences
Protein RefSeqs XP_056841364 (Get FASTA)   NCBI Sequence Viewer  
  XP_056841365 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL79260 (Get FASTA)   NCBI Sequence Viewer  
  EDL79261 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000054687.5
  ENSRNOP00000064891.3
Ensembl Acc Id: ENSRNOP00000068874   ⟸   ENSRNOT00000079212
Ensembl Acc Id: ENSRNOP00000045933   ⟸   ENSRNOT00000043238
Ensembl Acc Id: ENSRNOP00000054687   ⟸   ENSRNOT00000057878
Ensembl Acc Id: ENSRNOP00000070865   ⟸   ENSRNOT00000079781
Ensembl Acc Id: ENSRNOP00000068848   ⟸   ENSRNOT00000079887
Ensembl Acc Id: ENSRNOP00000064891   ⟸   ENSRNOT00000075832
Ensembl Acc Id: ENSRNOP00000067516   ⟸   ENSRNOT00000073412
RefSeq Acc Id: XP_056841364   ⟸   XM_056985384
- Peptide Label: isoform X1
- UniProtKB: F1M6A9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_056841365   ⟸   XM_056985385
- Peptide Label: isoform X2
Protein Domains
DAGKc

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0R652-F1-model_v2 AlphaFold M0R652 1-509 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1561057 AgrOrtholog
BioCyc Gene G2FUF-49245 BioCyc
Ensembl Genes ENSRNOG00000030212 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000057878.6 UniProtKB/TrEMBL
  ENSRNOT00000075832.3 UniProtKB/TrEMBL
Gene3D-CATH 2.60.200.40 UniProtKB/TrEMBL
InterPro ATP-NAD_kinase_dom_1 UniProtKB/TrEMBL
  CERK_C UniProtKB/TrEMBL
  Diacylglycerol_kinase_cat_dom UniProtKB/TrEMBL
  Lipid_Phosphate_FormReg UniProtKB/TrEMBL
  NAD/diacylglycerol_kinase UniProtKB/TrEMBL
NCBI Gene 502640 ENTREZGENE
PANTHER CERAMIDE KINASE-LIKE PROTEIN UniProtKB/TrEMBL
  SPHINGOSINE KINASE UniProtKB/TrEMBL
Pfam CERK_C UniProtKB/TrEMBL
  DAGK_cat UniProtKB/TrEMBL
PhenoGen Cerkl PhenoGen
PROSITE DAGK UniProtKB/TrEMBL
RatGTEx ENSRNOG00000030212 RatGTEx
Superfamily-SCOP SSF111331 UniProtKB/TrEMBL
UniProt F1M6A9 ENTREZGENE, UniProtKB/TrEMBL
  M0R652_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-11-08 Cerkl  CERK like autophagy regulator  Cerkl  ceramide kinase-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-04-23 Cerkl  ceramide kinase-like  RGD1561057  similar to ceramide kinase-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1561057  similar to ceramide kinase-like   RGD1561057_predicted  similar to ceramide kinase-like (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1561057_predicted  similar to ceramide kinase-like (predicted)  LOC502640  similar to ceramide kinase-like  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC502640  similar to ceramide kinase-like      Symbol and Name status set to provisional 70820 PROVISIONAL