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55 records found for search term Igf1
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
2868Igf1insulin-like growth factor 1ENCODES a protein that exhibits hormone activity; insulin-like growth factor receptor binding; protein serine/threonine kinase activator activity; INVOLVED IN bone development; cardiac atrium development; cellular response to dexamethasone stimulus; PARTICIPATES IN altered insulin-like growth factor72416960824249446Rat1379symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
10765Igf1insulin-like growth factor 1This gene encodes a member of the insulin-like growth factor (IGF) family of proteins that promote growth and development during fetal and postnatal life. This gene is predominantly expressed in the liver and the encoded protein undergoes proteolytic processing to generate a disulfide-linked mature 108769412787772909Mouse1573symbol , PhenoGengene, protein-coding, REVIEWED [RefSeq]
70506IGF1insulin like growth factor 1The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of in12102395874102481839Human1422symbol , COSMIC , Human Proteome Map , old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
8738804Igf1insulin like growth factor 1ENCODES a protein that exhibits growth factor activity (ortholog); hormone activity (ortholog); insulin receptor binding (ortholog); INVOLVED IN activation of protein kinase B activity (ortholog); blood vessel remodeling (ortholog); bone development (ortholog); PARTICIPATES IN altered insulin-like gNW_0049554053750583037582152Chinchilla439symbol , descriptiongene, protein-coding, MODEL [RefSeq]
12008691IGF1insulin like growth factor 1ENCODES a protein that exhibits hormone activity (ortholog); insulin-like growth factor receptor binding (ortholog); integrin binding (ortholog); INVOLVED IN activation of protein kinase B activity (ortholog); blood vessel remodeling (ortholog); bone development (ortholog); PARTICIPATES IN altered i1299986887100066773Bonobo437symbol , descriptiongene, protein-coding, MODEL [RefSeq]
12378133IGF1insulin like growth factor 1ENCODES a protein that exhibits hormone activity (ortholog); insulin-like growth factor receptor binding (ortholog); protein serine/threonine kinase activator activity (ortholog); INVOLVED IN activation of protein kinase B activity (ortholog); blood vessel remodeling (ortholog); bone development (or154120332041275964Dog443symbol , descriptiongene, protein-coding, VALIDATED [RefSeq]
12721362Igf1insulin like growth factor 1ENCODES a protein that exhibits hormone activity (ortholog); insulin-like growth factor receptor binding (ortholog); protein serine/threonine kinase activator activity (ortholog); INVOLVED IN activation of protein kinase B activity (ortholog); blood vessel remodeling (ortholog); bone development (orNW_0049364921170962311784028Squirrel439symbolgene, protein-coding, MODEL [RefSeq]
14261254IGF1insulin like growth factor 1ENCODES a protein that exhibits hormone activity (ortholog); insulin-like growth factor receptor binding (ortholog); protein serine/threonine kinase activator activity (ortholog); INVOLVED IN positive regulation of cell population proliferation; activation of protein kinase B activity (ortholog); blPig458symbol , descriptiongene, protein-coding, VALIDATED [RefSeq]
18342977IGF1insulin like growth factor 1ENCODES a protein that exhibits hormone activity (ortholog); insulin-like growth factor receptor binding (ortholog); protein serine/threonine kinase activator activity (ortholog); INVOLVED IN activation of protein kinase B activity (ortholog); blood vessel remodeling (ortholog); bone development (orGreen Monkey438symbolgene, protein-coding, MODEL [RefSeq]
18902774Igf1insulin like growth factor 1ENCODES a protein that exhibits hormone activity (ortholog); insulin receptor binding (ortholog); insulin-like growth factor receptor binding (ortholog); INVOLVED IN activation of protein kinase B activity (ortholog); blood vessel remodeling (ortholog); bone development (ortholog); PARTICIPATES IN aNaked Mole-Rat438symbol , descriptiongene, protein-coding, MODEL [RefSeq]
155253900igf1Tropical Clawed Frogsymbolgene, null
626154879Igf1insulin like growth factor 1ENCODES a protein that exhibits growth factor activity (ortholog); hormone activity (ortholog); insulin receptor binding (ortholog); INVOLVED IN activation of protein kinase B activity (ortholog); blood vessel remodeling (ortholog); bone development (ortholog); PARTICIPATES IN altered insulin-like gBlack Rat439symbol , descriptiongene, protein-coding, MODEL [RefSeq]
155246436igf1.LAfrican Clawed Frogsymbolgene, null
405857508igf1.LAfrican Clawed Frogsymbolgene, null
405862897igf1.LAfrican Clawed Frogsymbolgene, null
405863565igf1.LAfrican Clawed Frogsymbolgene, null
405864141igf1.LAfrican Clawed Frogsymbolgene, null
626180055igf1.LAfrican Clawed Frogsymbolgene, null
155253899igf1.SAfrican Clawed Frogsymbolgene, null
2869Igf1rinsulin-like growth factor 1 receptorENCODES a protein that exhibits G-protein alpha-subunit binding; insulin receptor substrate binding; insulin-like growth factor receptor activity; INVOLVED IN axonogenesis; cardiac atrium development; cellular response to aldosterone; PARTICIPATES IN insulin-like growth factor signaling pathway; E-c1130959787131248664Rat765symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
10766Igf1rinsulin-like growth factor I receptorEnables insulin-like growth factor binding activity and insulin-like growth factor receptor activity. Involved in several processes, including adrenal gland development; insulin-like growth factor receptor signaling pathway; and positive regulation of metabolic process. Acts upstream of or within se76760148667883416Mouse928symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
68997IGF1Rinsulin like growth factor 1 receptorThis receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant ti159864853998964530Human936symbol , old_gene_name , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
8755348Igf1rinsulin like growth factor 1 receptorENCODES a protein that exhibits G-protein alpha-subunit binding (ortholog); identical protein binding (ortholog); insulin binding (ortholog); INVOLVED IN adrenal gland development (ortholog); amyloid-beta clearance (ortholog); animal organ morphogenesis (ortholog); PARTICIPATES IN E-cadherin signaliNW_0049554162610109026382660Chinchilla274symbol , descriptiongene, protein-coding, MODEL [RefSeq]
11760001IGF1Rinsulin like growth factor 1 receptorENCODES a protein that exhibits G-protein alpha-subunit binding (ortholog); insulin receptor substrate binding (ortholog); insulin-like growth factor receptor activity (ortholog); INVOLVED IN adrenal gland development (ortholog); animal organ morphogenesis (ortholog); axonogenesis (ortholog); PARTIC157733292677648474Bonobo296symbolgene, protein-coding, MODEL [RefSeq]
12263935IGF1Rinsulin like growth factor 1 receptorENCODES a protein that exhibits G-protein alpha-subunit binding (ortholog); identical protein binding (ortholog); insulin binding (ortholog); INVOLVED IN adrenal gland development (ortholog); amyloid-beta clearance (ortholog); animal organ morphogenesis (ortholog); PARTICIPATES IN E-cadherin signali34179533742096255Dog283symbol , descriptiongene, protein-coding, MODEL [RefSeq]
12550680Igf1rinsulin like growth factor 1 receptorENCODES a protein that exhibits G-protein alpha-subunit binding (ortholog); insulin receptor substrate binding (ortholog); insulin-like growth factor receptor activity (ortholog); INVOLVED IN adrenal gland development (ortholog); animal organ morphogenesis (ortholog); axonogenesis (ortholog); PARTICNW_00493648345639954860231Squirrel293symbolgene, protein-coding, MODEL [RefSeq]
14131810IGF1Rinsulin like growth factor 1 receptorENCODES a protein that exhibits G-protein alpha-subunit binding (ortholog); insulin receptor substrate binding (ortholog); insulin-like growth factor binding (ortholog); INVOLVED IN adrenal gland development (ortholog); animal organ morphogenesis (ortholog); axonogenesis (ortholog); PARTICIPATES IN Pig305symbolgene, protein-coding, PROVISIONAL [RefSeq]
18404165IGF1Rinsulin like growth factor 1 receptorENCODES a protein that exhibits G-protein alpha-subunit binding (ortholog); insulin receptor substrate binding (ortholog); insulin-like growth factor receptor activity (ortholog); INVOLVED IN adrenal gland development (ortholog); animal organ morphogenesis (ortholog); axonogenesis (ortholog); PARTICGreen Monkey290symbolgene, protein-coding, MODEL [RefSeq]
18934082Igf1rinsulin like growth factor 1 receptorENCODES a protein that exhibits G-protein alpha-subunit binding (ortholog); identical protein binding (ortholog); insulin binding (ortholog); INVOLVED IN adrenal gland development (ortholog); amyloid-beta clearance (ortholog); animal organ morphogenesis (ortholog); PARTICIPATES IN E-cadherin signaliNaked Mole-Rat286symbol , descriptiongene, protein-coding, MODEL [RefSeq]
155231910igf1rTropical Clawed Frogsymbolgene, null
5139313Igf1itinsulin-like growth factor 1, intronic transcriptMousesymbol , PhenoGengene, ncrna
1618629Igf1osinsulin-like growth factor 1, opposite strandINTERACTS WITH 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene; 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl108766261887699255Mouse5symbol , PhenoGengene, ncrna, MODEL [RefSeq]
155231909igf1r.LAfrican Clawed Frogsymbolgene, null
155248191igf1r.SAfrican Clawed Frogsymbolgene, null
617154640IGF1R-AS2IGF1R antisense RNA 2Humansymbol , GTEx , COSMIC , name , Human Proteome Mapgene, ncrna
9589867IRAINIGF1R antisense imprinted non-protein coding RNAThis gene expresses a long non-coding RNA in antisense to the insulin-like growth factor type I receptor (IGF1R) gene. This transcript is imprinted and expressed from the paternal allele. It interacts with chromatin and may promote long-range DNA interactions th159864586398650787Humanname , description , old_gene_symbolgene, ncrna, REVIEWED [RefSeq]
735623AKT3AKT serine/threonine kinase 3The protein encoded by this gene is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferat1243488233243851079Human353descriptiongene, protein-coding, REVIEWED [RefSeq]
1319124EHD1EH domain containing 1This gene belongs to a highly conserved gene family encoding EPS15 homology (EH) domain-containing proteins. The protein-binding EH domain was first noted in EPS15, a substrate for the epidermal growth factor receptor. The EH domain has been shown to be an important motif in proteins involved in pro116485164264879693Human224descriptiongene, protein-coding, REVIEWED [RefSeq]
1352815SOCS2suppressor of cytokine signaling 2This gene encodes a member of the suppressor of cytokine signaling (SOCS) family. SOCS family members are cytokine-inducible negative regulators of cytokine receptor signaling via the Janus kinase/signal transducer and activation of transcription pathway (the JAK/STAT pathway). SOCS family proteins 129356996993626236Human320descriptiongene, protein-coding, REVIEWED [RefSeq]
16572283AC055807.1novel transcript, antisense to IGF1RHumannamegene, lncrna
16562312AC069029.1novel transcript, antisense to IGF1RHumannamegene, lncrna
16568425AC118658.1novel transcript, sense intronic to IGF1RHumannamegene, lncrna
16562229AC036108.1novel transcript, antisense to IGF1R and SYNMHumannamegene, lncrna
9589849LUNAR1leukemia-associated non-coding IGF1R activator RNA 1This gene is thought to produce a functional long non-coding RNA. It is regulated by Notch and is overexpressed in T cell acute lymphoblastic leukemia. The transcript acts as a positive regulator of cell division by promoting expression of the insulin-like growth factor type I receptor (IGF1159901470499031050Human3name , descriptiongene, ncrna, VALIDATED [RefSeq]
1310613Itgavintegrin subunit alpha VENCODES a protein that exhibits signaling receptor binding; C-X3-C chemokine binding (ortholog); collagen binding (ortholog); INVOLVED IN angiogenesis; cell migration; positive regulation of cell population proliferation; PARTICIPATES IN integrin mediated signaling pathway; platelet-derived growth f38924538289333512Rat373descriptiongene, protein-coding, VALIDATED [RefSeq]
8806657Itgavintegrin subunit alpha VENCODES a protein that exhibits C-X3-C chemokine binding (ortholog); collagen binding (ortholog); coreceptor activity (ortholog); INVOLVED IN angiogenesis (ortholog); apolipoprotein A-I-mediated signaling pathway (ortholog); apoptotic cell clearance (ortholog); PARTICIPATES IN integrin mediated signNW_0049554031158853611669809Chinchilla125descriptiongene, protein-coding, MODEL [RefSeq]
11754811ITGAVintegrin subunit alpha VENCODES a protein that exhibits collagen binding (ortholog); signaling receptor binding (ortholog); transforming growth factor beta binding (ortholog); INVOLVED IN angiogenesis (ortholog); apoptotic cell clearance (ortholog); blood vessel development (ortholog); PARTICIPATES IN integrin mediated sig2B7388096273972486Bonobo139descriptiongene, protein-coding, MODEL [RefSeq]
12288715ITGAVintegrin subunit alpha VENCODES a protein that exhibits collagen binding (ortholog); signaling receptor binding (ortholog); transforming growth factor beta binding (ortholog); INVOLVED IN angiogenesis (ortholog); apoptotic cell clearance (ortholog); blood vessel development (ortholog); PARTICIPATES IN integrin mediated sig362881521528890569Dog133descriptiongene, protein-coding, MODEL [RefSeq]
12600844Itgavintegrin subunit alpha VENCODES a protein that exhibits collagen binding (ortholog); signaling receptor binding (ortholog); transforming growth factor beta binding (ortholog); INVOLVED IN angiogenesis (ortholog); apoptotic cell clearance (ortholog); blood vessel development (ortholog); PARTICIPATES IN integrin mediated sigNW_0049365061075011610839018Squirrel134descriptiongene, protein-coding, MODEL [RefSeq]
18796818ITGAVintegrin subunit alpha VENCODES a protein that exhibits collagen binding (ortholog); signaling receptor binding (ortholog); transforming growth factor beta binding (ortholog); INVOLVED IN angiogenesis (ortholog); apoptotic cell clearance (ortholog); blood vessel development (ortholog); PARTICIPATES IN integrin mediated sigGreen Monkey137descriptiongene, protein-coding, MODEL [RefSeq]
18903000Itgavintegrin subunit alpha VENCODES a protein that exhibits C-X3-C chemokine binding (ortholog); collagen binding (ortholog); coreceptor activity (ortholog); INVOLVED IN angiogenesis (ortholog); apolipoprotein A-I-mediated signaling pathway (ortholog); apoptotic cell clearance (ortholog); PARTICIPATES IN integrin mediated signNaked Mole-Rat123descriptiongene, protein-coding, MODEL [RefSeq]
626027469Itgavintegrin subunit alpha VENCODES a protein that exhibits C-X3-C chemokine binding (ortholog); collagen binding (ortholog); coreceptor activity (ortholog); INVOLVED IN angiogenesis (ortholog); apolipoprotein A-I-mediated signaling pathway (ortholog); apoptotic cell clearance (ortholog); PARTICIPATES IN integrin mediated signBlack Rat125descriptiongene, protein-coding, MODEL [RefSeq]
8890490Itgb3integrin subunit beta 3ENCODES a protein that exhibits C-X3-C chemokine binding (ortholog); cell adhesion molecule binding (ortholog); cell adhesion receptor activity (ortholog); INVOLVED IN apolipoprotein A-I-mediated signaling pathway (ortholog); apoptotic cell clearance (ortholog); blood coagulation, fibrin clot formatNW_00495547897881929830254Chinchilla248descriptiongene, protein-coding, MODEL [RefSeq]
12349367ITGB3integrin subunit beta 3ENCODES a protein that exhibits C-X3-C chemokine binding (ortholog); cell adhesion molecule binding (ortholog); cell adhesion receptor activity (ortholog); INVOLVED IN apolipoprotein A-I-mediated signaling pathway (ortholog); apoptotic cell clearance (ortholog); blood coagulation, fibrin clot format991796679231061Dog261descriptiongene, protein-coding, PROVISIONAL [RefSeq]
18901528Itgb3integrin subunit beta 3ENCODES a protein that exhibits C-X3-C chemokine binding (ortholog); cell adhesion molecule binding (ortholog); cell adhesion receptor activity (ortholog); INVOLVED IN apolipoprotein A-I-mediated signaling pathway (ortholog); blood coagulation, fibrin clot formation (ortholog); cell-cell adhesion meNaked Mole-Rat264descriptiongene, protein-coding, MODEL [RefSeq]