Itgav (integrin subunit alpha V) - Rat Genome Database

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Gene: Itgav (integrin subunit alpha V) Chinchilla lanigera
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Symbol: Itgav
Name: integrin subunit alpha V
RGD ID: 8806657
Description: ENCODES a protein that exhibits C-X3-C chemokine binding (ortholog); extracellular matrix binding (ortholog); extracellular matrix protein binding (ortholog); INVOLVED IN angiogenesis (ortholog); apolipoprotein A-I-mediated signaling pathway (ortholog); apoptotic cell clearance (ortholog); PARTICIPATES IN integrin mediated signaling pathway; platelet-derived growth factor signaling pathway; sphingosine 1-phosphate signaling pathway; ASSOCIATED WITH abdominal aortic aneurysm (ortholog); acute myeloid leukemia (ortholog); Cerebral Hemorrhage (ortholog); FOUND IN alphav-beta3 integrin-HMGB1 complex (ortholog); alphav-beta3 integrin-IGF-1-IGF1R complex (ortholog); cell surface (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: integrin alpha-V; integrin, alpha V
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540311,592,339 - 11,659,297 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540311,588,536 - 11,669,809 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

References


Genomics

Comparative Map Data
Itgav
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540311,592,339 - 11,659,297 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540311,588,536 - 11,669,809 (-)NCBIChiLan1.0ChiLan1.0
ITGAV
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2186,590,056 - 186,680,901 (+)EnsemblGRCh38hg38GRCh38
GRCh382186,590,056 - 186,680,901 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372187,454,783 - 187,545,628 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362187,163,045 - 187,253,873 (+)NCBINCBI36hg18NCBI36
Build 342187,280,305 - 187,371,133NCBI
Celera2181,050,405 - 181,141,257 (+)NCBI
Cytogenetic Map2q32.1NCBI
HuRef2179,314,524 - 179,405,486 (+)NCBIHuRef
CHM1_12187,460,842 - 187,551,625 (+)NCBICHM1_1
Itgav
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39283,551,625 - 83,637,261 (+)NCBIGRCm39mm39
GRCm39 Ensembl283,554,741 - 83,637,260 (+)Ensembl
GRCm38283,722,303 - 83,806,917 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl283,724,397 - 83,806,916 (+)EnsemblGRCm38mm10GRCm38
MGSCv37283,564,554 - 83,647,073 (+)NCBIGRCm37mm9NCBIm37
MGSCv36283,525,354 - 83,604,646 (+)NCBImm8
Celera285,367,604 - 85,456,006 (+)NCBICelera
Cytogenetic Map2DNCBI
cM Map249.33NCBI
Itgav
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2368,838,524 - 68,926,653 (+)NCBI
Rnor_6.0 Ensembl371,114,100 - 71,202,411 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0371,113,269 - 71,205,958 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0377,643,270 - 77,731,358 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4366,953,403 - 67,029,774 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1366,848,789 - 66,926,146 (+)NCBI
Celera368,209,136 - 68,297,332 (+)NCBICelera
Cytogenetic Map3q24NCBI
ITGAV
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12B191,680,655 - 191,773,028 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B191,680,655 - 191,773,028 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02B73,880,962 - 73,972,486 (+)NCBIMhudiblu_PPA_v0panPan3
ITGAV
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13628,815,215 - 28,890,569 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3628,804,013 - 28,887,430 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3628,702,231 - 28,789,503 (+)NCBI
ROS_Cfam_1.03629,028,662 - 29,116,151 (+)NCBI
UMICH_Zoey_3.13629,087,085 - 29,173,016 (+)NCBI
UNSW_CanFamBas_1.03629,020,979 - 29,108,231 (+)NCBI
UU_Cfam_GSD_1.03629,188,373 - 29,276,043 (+)NCBI
Itgav
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303145,999,260 - 146,087,955 (+)NCBI
SpeTri2.0NW_00493650610,750,116 - 10,839,018 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ITGAV
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1591,604,676 - 91,711,840 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11591,604,666 - 91,711,843 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215101,654,958 - 101,717,935 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ITGAV
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11072,125,710 - 72,216,757 (+)NCBI
ChlSab1.1 Ensembl1072,125,962 - 72,216,809 (+)Ensembl
Itgav
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248993,235,434 - 3,292,584 (-)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000023054   ⟹   ENSCLAP00000022843
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540311,592,339 - 11,659,297 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000023055   ⟹   ENSCLAP00000022844
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540311,592,339 - 11,659,297 (-)Ensembl
RefSeq Acc Id: XM_005373337   ⟹   XP_005373394
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540311,590,935 - 11,669,809 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013512419   ⟹   XP_013367873
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540311,590,935 - 11,668,987 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013512423   ⟹   XP_013367877
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540311,588,536 - 11,668,987 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013512426   ⟹   XP_013367880
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540311,590,935 - 11,664,958 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005373394 (Get FASTA)   NCBI Sequence Viewer  
  XP_013367873 (Get FASTA)   NCBI Sequence Viewer  
  XP_013367877 (Get FASTA)   NCBI Sequence Viewer  
  XP_013367880 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005373394   ⟸   XM_005373337
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_013367877   ⟸   XM_013512423
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_013367873   ⟸   XM_013512419
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_013367880   ⟸   XM_013512426
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: ENSCLAP00000022843   ⟸   ENSCLAT00000023054
RefSeq Acc Id: ENSCLAP00000022844   ⟸   ENSCLAT00000023055


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000015669 Ensembl, ENTREZGENE
Ensembl Protein ENSCLAP00000022843 ENTREZGENE
Ensembl Transcript ENSCLAT00000023054 ENTREZGENE
NCBI Gene Itgav ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-16 Itgav  integrin subunit alpha V    integrin, alpha V  Symbol and/or name change 5135510 APPROVED