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Gene: ITGB3 (integrin subunit beta 3) Canis lupus familiaris
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Symbol: ITGB3
Name: integrin subunit beta 3
Description: ENCODES a protein that exhibits integrin binding (inferred); protein kinase C binding (inferred); INVOLVED IN apoptotic cell clearance (inferred); cell-substrate junction assembly (inferred); cellular response to platelet-derived growth factor stimulus (inferred); PARTICIPATES IN abciximab pharmacodynamics pathway; arrhythmogenic right ventricular cardiomyopathy pathway; cell-extracellular matrix signaling pathway; ASSOCIATED WITH Acute Coronary Syndrome (ortholog); acute myeloid leukemia (ortholog); Arterial Occlusive Diseases (ortholog); FOUND IN alpha9-beta1 integrin-ADAM8 complex (inferred); alphav-beta3 integrin-PKCalpha complex (inferred); apical plasma membrane (inferred)
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: glycoprotein GPIIIa; GPIIIA; integrin beta-3
Orthologs:
Homo sapiens (human) : ITGB3 (integrin subunit beta 3)  HGNC  Alliance
Mus musculus (house mouse) : Itgb3 (integrin beta 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Itgb3 (integrin subunit beta 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Itgb3 (integrin subunit beta 3)
Pan paniscus (bonobo/pygmy chimpanzee) : ITGB3 (integrin subunit beta 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Itgb3 (integrin subunit beta 3)
Sus scrofa (pig) : ITGB3 (integrin subunit beta 3)
Chlorocebus sabaeus (African green monkey) : ITGB3 (integrin subunit beta 3)
Heterocephalus glaber (naked mole-rat) : Itgb3 (integrin subunit beta 3)
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl99,182,562 - 9,231,451 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.199,179,667 - 9,231,061 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - uncurated

Genomics

Comparative Map Data

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on ITGB3
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 12349367
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2020-02-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.