Col1a2 (collagen type I alpha 2 chain) - Rat Genome Database

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Gene: Col1a2 (collagen type I alpha 2 chain) Rattus norvegicus
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Symbol: Col1a2
Name: collagen type I alpha 2 chain
RGD ID: 621351
Description: Predicted to enable several functions, including identical protein binding activity; platelet-derived growth factor binding activity; and protease binding activity. Predicted to be an extracellular matrix structural constituent conferring tensile strength. Involved in several processes, including cellular response to retinoic acid; cellular response to thyroid hormone stimulus; and response to norepinephrine. Predicted to be located in extracellular region. Predicted to be part of collagen type I trimer. Predicted to be active in collagen-containing extracellular matrix and extracellular space. Biomarker of hypothyroidism; muscular atrophy; pulmonary fibrosis; and ureteral obstruction. Human ortholog(s) of this gene implicated in Ehlers-Danlos syndrome (multiple); heart valve disease; intracranial aneurysm; osteogenesis imperfecta (multiple); and osteoporosis. Orthologous to human COL1A2 (collagen type I alpha 2 chain); PARTICIPATES IN endothelin signaling pathway; interleukin-4 signaling pathway; syndecan signaling pathway; INTERACTS WITH (S)-nicotine; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: alpha-2 type I collagen; collagen alpha-2(I) chain; collagen, type I, alpha 2; NEWGENE_621351; procollagen, type I, alpha 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8433,518,557 - 33,553,484 (+)NCBIGRCr8
mRatBN7.2432,563,938 - 32,598,868 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl432,563,381 - 32,598,867 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx437,550,562 - 37,585,439 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0433,476,688 - 33,511,565 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0431,846,998 - 31,881,902 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0431,534,225 - 31,569,152 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl431,534,225 - 31,569,151 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0429,442,828 - 29,478,616 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0431,405,253 - 31,440,180 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4429,393,645 - 29,428,572 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1429,431,383 - 29,467,014 (+)NCBI
Celera427,947,892 - 27,982,658 (+)NCBICelera
Cytogenetic Map4q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


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Col1a2RatAcute Liver Failure  IEP 7257539 RGD 
Col1a2RatDiabetic Nephropathies  ISOCOL1A2 (Homo sapiens)401851916mRNA:increased expression:nephron tubule (human)RGD 
Col1a2RatEhlers-Danlos syndrome  ISOCOL1A2 (Homo sapiens)1581198 RGD 
Col1a2RatExperimental Liver Cirrhosis  IEP 7257544 RGD 
Col1a2RatFetal Nutrition Disorders  IEP 155882570associated with maternal low protein diet and mRNA:increased expression:glomeruli (rat)RGD 
Col1a2Ratheart valve disease  ISOCOL1A2 (Homo sapiens)1581196 RGD 
Col1a2Ratheart valve disease  ISOCOL1A2 (Homo sapiens)1581198 RGD 
Col1a2Rathypothyroidism  IEP 7257542mRNA:increased expression:heart ventricleRGD 
Col1a2Ratintracranial aneurysm  ISOCOL1A2 (Homo sapiens)1581199 RGD 
Col1a2Ratmuscular atrophy  IEP 7257536 RGD 
Col1a2Ratosteogenesis imperfecta  ISOCol1a2 (Mus musculus)7248772DNA:deletion:exon:3983del (mouse)RGD 
Col1a2Ratosteogenesis imperfecta  ISOCOL1A2 (Homo sapiens)11667066DNA:mutation:exon:c.87T > C(human)RGD 
Col1a2Ratosteogenesis imperfecta  ISOCOL1A2 (Homo sapiens)1581197DNA:snp:cds:p.G328S (human)RGD 
Col1a2Ratosteogenesis imperfecta  ISOCOL1A2 (Homo sapiens)734804DNA:mutations and haplotype (human)RGD 
Col1a2Ratpulmonary fibrosis  IEP 7257543 RGD 
Col1a2RatTransplant Rejection  ISOCOL1A2 (Homo sapiens)7248773mRNA:increased expression:kidneyRGD 
Col1a2Ratureteral obstruction  IEP 5688341mRNA:increased expression:kidneyRGD 
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Col1a2RatARTERIAL DISSECTION  ISOCOL1A2 (Homo sapiens)8554872ClinVar Annotator: match by term: Predisposition to dissectionClinVarPMID:25741868 more ...
Col1a2RatBruck Syndrome 1  ISOCOL1A2 (Homo sapiens)8554872ClinVar Annotator: match by term: Bruck syndrome 1ClinVar 
Col1a2RatCombined Osteogenesis Imperfecta and Ehlers-Danlos Syndrome 2  ISOCOL1A2 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:10027910 more ...
Col1a2Ratconnective tissue disease  ISOCOL1A2 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:15172002 more ...
Col1a2Ratdentinogenesis imperfecta  ISOCOL1A2 (Homo sapiens)8554872ClinVar Annotator: match by term: Dentinogenesis imperfectaClinVarPMID:16705691 more ...
Col1a2RatDevelopmental Disabilities  ISOCOL1A2 (Homo sapiens)8554872ClinVar Annotator: match by term: Global developmental delayClinVarPMID:28492532 and PMID:30311386
Col1a2RatEhlers-Danlos syndrome  ISOCOL1A2 (Homo sapiens)8554872ClinVar Annotator: match by term: Ehlers-Danlos syndromeClinVarPMID:11288717 more ...
Col1a2RatEhlers-Danlos syndrome arthrochalasia type 1  ISOCOL1A2 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:17078022 more ...
Col1a2RatEhlers-Danlos syndrome arthrochalasia type 1  ISOCOL1A2 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:25441681 and PMID:28492532
Col1a2RatEhlers-Danlos syndrome arthrochalasia type 2  ISOCOL1A2 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:10807697 more ...
Col1a2RatEhlers-Danlos syndrome cardiac valvular type  ISOCOL1A2 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:11288717 more ...
Col1a2RatEhlers-Danlos syndrome classic type 1  ISOCOL1A2 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:11288717 more ...
Col1a2RatEhlers-Danlos syndrome classic type 1  ISOCOL1A2 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:10027910 more ...
Col1a2RatEhlers-Danlos syndrome classic type 1  ISOCOL1A2 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:10027910 more ...
Col1a2RatEhlers-Danlos syndrome classic type 2  ISOCOL1A2 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:11288717 more ...
Col1a2Ratgenetic disease  ISOCOL1A2 (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:10027910 more ...
Col1a2RatMarfan syndrome  ISOCOL1A2 (Homo sapiens)8554872ClinVar Annotator: match by term: Marfan syndrome and atypicalClinVarPMID:15172002 more ...
Col1a2RatMarfan syndrome  ISOCOL1A2 (Homo sapiens)8554872ClinVar Annotator: match by term: Marfan syndromeClinVarPMID:15172002 more ...
Col1a2Ratmyoclonic dystonia 11  ISOCOL1A2 (Homo sapiens)8554872ClinVar Annotator: match by term: Myoclonic dystonia 11ClinVarPMID:12821748 more ...
Col1a2Ratosteochondrodysplasia  ISOCOL1A2 (Homo sapiens)8554872ClinVar Annotator: match by term: Skeletal dysplasiaClinVarPMID:25741868
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Col1a2RatEhlers-Danlos syndrome cardiac valvular type  ISOCOL1A2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:15077201
Col1a2RatExperimental Liver Cirrhosis  ISOCOL1A2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:25380136
Col1a2RatFibrosis  ISOCOL1A2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:20388698
Col1a2Ratheart valve disease  ISOCOL1A2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:15077201
Col1a2Ratliver cirrhosis  ISOCOL1A2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:26396155
Col1a2Ratoral submucous fibrosis  ISOCOL1A2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:16311067
Col1a2Ratosteoarthritis  ISOCOL1A2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:18784066
Col1a2Ratosteogenesis imperfecta type 2  ISOCOL1A2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTD 
Col1a2Ratosteogenesis imperfecta type 3  ISOCOL1A2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTD 
Col1a2Ratosteoporosis  ISOCOL1A2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTD 
Col1a2RatSpontaneous Abortions  ISOCOL1A2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:18539642
Col1a2Ratsystemic scleroderma  ISOCOL1A2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:24706986
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Col1a2Ratosteogenesis imperfecta  ISSCol1a2 (Mus musculus)13592920 MouseDO 
Col1a2Ratosteogenesis imperfecta type 3  ISSCol1a2 (Mus musculus)13592920OMIM:259420MouseDO 

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Col1a2Rat(1->4)-beta-D-glucan multiple interactionsISOCol1a2 (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of COL1A2 mRNACTDPMID:36331819
Col1a2Rat(R)-camphor affects expressionISOCol1a2 (Mus musculus)6480464Camphor analog affects the expression of COL1A2 mRNACTDPMID:24704097
Col1a2Rat(S)-nicotine multiple interactionsISOCol1a2 (Mus musculus)6480464Nicotine promotes the reaction [Quartz results in increased expression of COL1A2 protein]CTDPMID:36868510
Col1a2Rat(S)-nicotine multiple interactionsEXP 6480464Nicotine promotes the reaction [Arginine results in increased expression of COL1A2 protein]CTDPMID:34153408
Col1a2Rat1,2-dimethylhydrazine multiple interactionsISOCol1a2 (Mus musculus)6480464Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of COL1A2 mRNA]CTDPMID:22206623
Col1a2Rat1,2-dimethylhydrazine increases expressionISOCol1a2 (Mus musculus)64804641 and 2-Dimethylhydrazine results in increased expression of COL1A2 mRNACTDPMID:22206623
Col1a2Rat1-naphthyl isothiocyanate increases expressionEXP 64804641-Naphthylisothiocyanate results in increased expression of COL1A2 mRNACTDPMID:25380136
Col1a2Rat1-octadec-9-enoylglycero-3-phosphate increases expressionISOCol1a2 (Mus musculus)6480464lysophosphatidic acid results in increased expression of COL1A2 mRNACTDPMID:24706986
Col1a2Rat1-octadec-9-enoylglycero-3-phosphate multiple interactionsISOCol1a2 (Mus musculus)6480464N-(4-chlorophenyl)-1-((3-(furan-2-yl)phenyl)carbonyl)piperidine-3-carboxamide inhibits the reaction [lysophosphatidic acid results in increased expression of COL1A2 mRNA]CTDPMID:24706986
Col1a2Rat17alpha-ethynylestradiol increases expressionISOCol1a2 (Mus musculus)6480464Ethinyl Estradiol results in increased expression of COL1A2 mRNACTDPMID:17942748
Col1a2Rat17alpha-ethynylestradiol increases expressionEXP 6480464Ethinyl Estradiol results in increased expression of COL1A2 mRNACTDPMID:12655037
Col1a2Rat17alpha-ethynylestradiol multiple interactionsISOCol1a2 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of COL1A2 mRNACTDPMID:17942748
Col1a2Rat17beta-estradiol decreases expressionISOCol1a2 (Mus musculus)6480464Estradiol results in decreased expression of COL1A2 mRNACTDPMID:19401787
Col1a2Rat17beta-estradiol multiple interactionsISOCOL1A2 (Homo sapiens)6480464[Estradiol co-treated with Progesterone] results in increased expression of COL1A2 mRNA and [Estradiol co-treated with TGFB1 protein] results in increased expression of COL1A2 mRNACTDPMID:20660070 and PMID:30165855
Col1a2Rat1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one decreases expressionISOCOL1A2 (Homo sapiens)64804641H-(1 more ...CTDPMID:22543296
Col1a2Rat1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one multiple interactionsISOCOL1A2 (Homo sapiens)64804641H-(1 more ...CTDPMID:22543296
Col1a2Rat2,2',4,4'-Tetrabromodiphenyl ether multiple interactionsISOCol1a2 (Mus musculus)6480464[Flame Retardants results in increased abundance of 2 more ...CTDPMID:38995820
Col1a2Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOCol1a2 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of COL1A2 mRNACTDPMID:17942748
Col1a2Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOCOL1A2 (Homo sapiens)6480464Tetrachlorodibenzodioxin affects the expression of COL1A2 mRNACTDPMID:36370075
Col1a2Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of COL1A2 mRNACTDPMID:32109520 and PMID:33387578

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Biological Process
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Col1a2Ratblood vessel development involved_inISOCOL1A2 (Homo sapiens)1624291 PMID:17211858RGDPMID:17211858
Col1a2Ratbone mineralization acts_upstream_of_or_withinISOCol1a2 (Mus musculus)1624291MGI:1856327 PMID:22910579RGDPMID:22910579
Col1a2Ratcellular response to aldehyde  IEP 7257541 RGD 
Col1a2Ratcellular response to amino acid stimulus acts_upstream_of_or_withinISOCol1a2 (Mus musculus)1624291 PMID:20548288RGDPMID:20548288
Col1a2Ratcellular response to retinoic acid  IEP 5688233 RGD 
Col1a2Ratcellular response to thyroid hormone stimulus  IEP 7257545 RGD 
Col1a2Ratcollagen fibril organization involved_inISOCOL1A2 (Homo sapiens)1624291 PMID:17211858 and PMID:18375391RGDPMID:17211858 and PMID:18375391
Col1a2Ratcollagen metabolic process acts_upstream_of_or_withinISOCol1a2 (Mus musculus)1624291MGI:1856327 PMID:22910579RGDPMID:22910579
Col1a2Ratextracellular matrix assembly acts_upstream_of_or_withinISOCol1a2 (Mus musculus)1624291MGI:1856327 PMID:22910579RGDPMID:22910579
Col1a2Ratprotein heterotrimerization acts_upstream_of_or_withinISOCol1a2 (Mus musculus)1624291 PMID:9213002RGDPMID:9213002
Col1a2Ratregulation of blood pressure involved_inISOCOL1A2 (Homo sapiens)1624291 PMID:17334644RGDPMID:17334644
Col1a2Ratresponse to norepinephrine  IEP 7257546 RGD 
Col1a2RatRho protein signal transduction involved_inISOCOL1A2 (Homo sapiens)1624291 PMID:17217948RGDPMID:17217948
Col1a2Ratskeletal system development involved_inISOCOL1A2 (Homo sapiens)1624291 PMID:17955022 more ...RGDPMID:17955022 more ...
Col1a2Ratskin morphogenesis involved_inISOCOL1A2 (Homo sapiens)1624291 PMID:17211858RGDPMID:17211858
Col1a2Rattransforming growth factor beta receptor signaling pathway involved_inISOCOL1A2 (Homo sapiens)1624291 PMID:17217948RGDPMID:17217948
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Cellular Component
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Col1a2Ratcollagen trimer part_ofIEAUniProtKB-KW:KW-01761600115GO_REF:0000043UniProtGO_REF:0000043
Col1a2Ratcollagen trimer part_ofISOCol1a2 (Mus musculus)1624291 PMID:10608859 more ...RGDPMID:10608859 more ...
Col1a2Ratcollagen type I trimer part_ofISOCOL1A2 (Homo sapiens)1624291 PMID:17955022 more ...RGDPMID:17955022 more ...
Col1a2Ratcollagen type I trimer part_ofIBAMGI:88468 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Col1a2Ratcollagen type I trimer part_ofISOCol1a2 (Mus musculus)1624291 PMID:7825727RGDPMID:7825727
Col1a2Ratcollagen-containing extracellular matrix located_inISOCol1a2 (Mus musculus)1624291 PMID:34368841RGDPMID:34368841
Col1a2Ratcollagen-containing extracellular matrix is_active_inIBAFB:FBgn0000299 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Col1a2Ratextracellular region located_inTAS 1600115Reactome:R-NUL-2465871ReactomeReactome:R-NUL-2465871
Col1a2Ratextracellular region located_inIEAUniProtKB-SubCell:SL-02431600115GO_REF:0000044UniProtGO_REF:0000044
Col1a2Ratextracellular region located_inIEAUniProtKB-KW:KW-09641600115GO_REF:0000043UniProtGO_REF:0000043
Col1a2Ratextracellular region located_inTAS 1600115Reactome:R-NUL-4084908ReactomeReactome:R-NUL-4084908
Col1a2Ratextracellular region located_inTAS 1600115Reactome:R-NUL-2731094ReactomeReactome:R-NUL-2731094
Col1a2Ratextracellular region located_inTAS 1600115Reactome:R-RNO-4086208ReactomeReactome:R-RNO-4086208
Col1a2Ratextracellular region located_inTAS 1600115Reactome:R-NUL-2537524ReactomeReactome:R-NUL-2537524
Col1a2Ratextracellular space located_inISOCOL1A2 (Homo sapiens)1624291 PMID:18375391RGDPMID:18375391
Col1a2Ratextracellular space located_inISOCol1a2 (Mus musculus)1624291 PMID:20053668RGDPMID:20053668
Col1a2Ratextracellular space is_active_inIBAMGI:88452 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
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Imported Annotations - KEGG (archival)

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Col1a2Ratcell-extracellular matrix signaling pathway  IEA 6907045 KEGGrno:04512
Col1a2RatEntamoebiasis pathway  IEA 6907045 KEGGrno:05146

Imported Annotations - PID (archival)

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Col1a2Ratendothelin signaling pathway  ISOCOL1A2 (Homo sapiens)6484113 PIDPID:200005
Col1a2Ratinterleukin-4 signaling pathway  ISOCOL1A2 (Homo sapiens)6484113 PIDPID:200022
Col1a2Ratsyndecan signaling pathway  ISOCOL1A2 (Homo sapiens)6484113 PIDPID:200156

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Reference Title
Reference Citation
1. Aldehydes potentiate alpha(2)(I) collagen gene activity by JNK in hepatic stellate cells. Anania FA, etal., Free Radic Biol Med. 2001 Apr 15;30(8):846-57.
2. Changes in expression of the albumin, fibronectin and type I procollagen genes in CCl4-induced liver fibrosis: effect of pyridoxol L,2-pyrrolidon-5 carboxylate. Arosio B, etal., Pharmacol Toxicol. 1993 Dec;73(6):301-4.
3. Effect of norepinephrine on myocardial collagen gene expression and response of cardiac fibroblasts after norepinephrine treatment. Bhambi B and Eghbali M, Am J Pathol. 1991 Nov;139(5):1131-42.
4. Defective pro alpha 2(I) collagen synthesis in a recessive mutation in mice: a model of human osteogenesis imperfecta. Chipman SD, etal., Proc Natl Acad Sci U S A. 1993 Mar 1;90(5):1701-5.
5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
6. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
7. TGF-beta1 and TNF-alpha are involved in the transcription of type I collagen alpha2 gene in soleus muscle atrophied by mechanical unloading. Hirose T, etal., J Appl Physiol. 2008 Jan;104(1):170-7. Epub 2007 Oct 4.
8. Upregulation of collagen type I gene expression in the ventricular myocardium of thyroidectomized male and female rats. Klein LE, etal., J Mol Cell Cardiol. 1996 Jan;28(1):33-42.
9. Mutational spectrum of type I collagen genes in Korean patients with osteogenesis imperfecta. Lee KS, etal., Hum Mutat. 2006 Jun;27(6):599.
10. Integrative urinary peptidomics in renal transplantation identifies biomarkers for acute rejection. Ling XB, etal., J Am Soc Nephrol. 2010 Apr;21(4):646-53. doi: 10.1681/ASN.2009080876. Epub 2010 Feb 11.
11. Total absence of the alpha2(I) chain of collagen type I causes a rare form of Ehlers-Danlos syndrome with hypermobility and propensity to cardiac valvular problems. Malfait F, etal., J Med Genet. 2006 Jul;43(7):e36.
12. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
13. Mouse Genome Database (MGD) Mouse Genome Database (MGD)
14. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
15. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
16. Online Mendelian Inheritance in Man, OMIM (TM). Online Mendelian Inheritance in Man, OMIM (TM).
17. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
18. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
19. GOA pipeline RGD automated data pipeline
20. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
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PMID:1590760   PMID:4435743   PMID:4636752   PMID:4763308   PMID:5337886   PMID:5443712   PMID:5544653   PMID:5785232   PMID:6395893   PMID:7825727   PMID:8686743   PMID:8841196  
PMID:8900172   PMID:9213002   PMID:10608859   PMID:12477932   PMID:12704794   PMID:12968017   PMID:14559231   PMID:17211858   PMID:17217948   PMID:17334644   PMID:17662583   PMID:17955022  
PMID:18375391   PMID:19156436   PMID:19362560   PMID:19755419   PMID:19932771   PMID:20053668   PMID:20548288   PMID:20551380   PMID:21362503   PMID:22049076   PMID:22910579   PMID:23399546  
PMID:23658023   PMID:24006456   PMID:24782617   PMID:25655816   PMID:25931508   PMID:27068509   PMID:27559042   PMID:30053369   PMID:36324232  



Col1a2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8433,518,557 - 33,553,484 (+)NCBIGRCr8
mRatBN7.2432,563,938 - 32,598,868 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl432,563,381 - 32,598,867 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx437,550,562 - 37,585,439 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0433,476,688 - 33,511,565 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0431,846,998 - 31,881,902 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0431,534,225 - 31,569,152 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl431,534,225 - 31,569,151 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0429,442,828 - 29,478,616 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0431,405,253 - 31,440,180 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4429,393,645 - 29,428,572 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1429,431,383 - 29,467,014 (+)NCBI
Celera427,947,892 - 27,982,658 (+)NCBICelera
Cytogenetic Map4q21NCBI
COL1A2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38794,394,895 - 94,431,227 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl794,394,895 - 94,431,227 (+)EnsemblGRCh38hg38GRCh38
GRCh37794,024,207 - 94,060,539 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36793,861,809 - 93,898,480 (+)NCBINCBI36Build 36hg18NCBI36
Build 34793,668,523 - 93,705,195NCBI
Celera788,722,142 - 88,758,790 (+)NCBICelera
Cytogenetic Map7q21.3NCBI
HuRef788,631,579 - 88,668,235 (+)NCBIHuRef
CHM1_1793,953,972 - 93,990,650 (+)NCBICHM1_1
T2T-CHM13v2.0795,630,848 - 95,667,187 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2793,353,052 - 93,389,700 (+)NCBI
Col1a2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3964,505,618 - 4,541,543 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl64,504,814 - 4,541,544 (+)EnsemblGRCm39 Ensembl
GRCm3864,505,618 - 4,541,543 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl64,504,814 - 4,541,544 (+)EnsemblGRCm38mm10GRCm38
MGSCv3764,455,697 - 4,491,543 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3664,455,761 - 4,490,730 (+)NCBIMGSCv36mm8
Celera64,648,226 - 4,684,066 (+)NCBICelera
Cytogenetic Map6A1NCBI
cM Map61.81NCBI
Col1a2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543211,128,112 - 11,163,302 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543211,127,961 - 11,164,145 (+)NCBIChiLan1.0ChiLan1.0
COL1A2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26112,232,392 - 112,268,547 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17160,497,349 - 160,533,186 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0786,344,657 - 86,381,282 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1799,935,185 - 99,971,810 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl799,935,185 - 99,971,803 (+)Ensemblpanpan1.1panPan2
COL1A2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11419,883,731 - 19,919,527 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1419,883,868 - 19,919,527 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1419,443,112 - 19,478,898 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01419,699,099 - 19,734,901 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1419,699,098 - 19,734,902 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11419,850,793 - 19,886,662 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01419,585,955 - 19,621,759 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01419,843,097 - 19,878,889 (+)NCBIUU_Cfam_GSD_1.0
Col1a2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511833,176,893 - 33,212,967 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365855,651,180 - 5,685,923 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365855,650,322 - 5,686,393 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
COL1A2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl974,173,931 - 74,210,397 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1974,174,484 - 74,210,407 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2981,357,192 - 81,393,118 (+)NCBISscrofa10.2Sscrofa10.2susScr3
COL1A2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12154,602,780 - 54,639,832 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2154,602,398 - 54,632,780 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604249,682,896 - 49,719,954 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Col1a2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248131,174,224 - 1,209,616 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248131,174,071 - 1,209,929 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Col1a2
83 total Variants

Predicted Target Of
Summary Value
Count of predictions:48
Count of miRNA genes:30
Interacting mature miRNAs:41
Transcripts:ENSRNOT00000016423
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 33 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
2302371Stl22Serum triglyceride level QTL 225.15blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521829457114705Rat
2303585Bw86Body weight QTL 864body mass (VT:0001259)body weight (CMO:0000012)41467806559678065Rat
8552906Pigfal3Plasma insulin-like growth factor 1 level QTL 3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)41008408955084089Rat
1357341Gluco5Glucose level QTL 56.4adipocyte free fatty acid secretion trait (VT:0010465)absolute change in adipocyte free fatty acid secretion per unit volume (CMO:0001446)4133250345Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)426775591168368347Rat
1357343Gluco4Glucose level QTL 40.00002adipocyte glucose uptake trait (VT:0004185)adipocyte maximal glucose uptake to basal glucose uptake ratio (CMO:0000874)4133250345Rat
6478766Anxrr47Anxiety related response QTL 470.09637locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)41008408955084089Rat
70222Eae2Experimental allergic encephalomyelitis QTL 24.3nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)42133334339505420Rat
631642Stl2Serum triglyceride level QTL 23.3blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521917856647776Rat
6478769Anxrr48Anxiety related response QTL 480.02514locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)41008408955084089Rat

1 to 10 of 33 rows
D4Rat151  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8433,538,597 - 33,538,816 (+)Marker Load Pipeline
mRatBN7.2432,583,980 - 32,584,199 (+)MAPPERmRatBN7.2
Rnor_6.0431,554,266 - 31,554,484NCBIRnor6.0
Rnor_6.0429,549,895 - 29,550,113NCBIRnor6.0
Rnor_5.0431,425,294 - 31,425,512UniSTSRnor5.0
Rnor_5.0429,463,219 - 29,463,437UniSTSRnor5.0
RGSC_v3.4429,413,655 - 29,414,068RGDRGSC3.4
RGSC_v3.4429,413,686 - 29,413,904UniSTSRGSC3.4
RGSC_v3.1429,452,129 - 29,452,347RGD
Celera427,967,860 - 27,968,078UniSTS
RH 3.4 Map4449.82UniSTS
RH 3.4 Map4449.82RGD
RH 2.0 Map4215.3RGD
SHRSP x BN Map417.0799RGD
Cytogenetic Map4q13UniSTS
RH132451  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8433,553,224 - 33,553,416 (+)Marker Load Pipeline
mRatBN7.2432,598,608 - 32,598,800 (+)MAPPERmRatBN7.2
Rnor_6.0431,568,893 - 31,569,084NCBIRnor6.0
Rnor_6.0429,564,522 - 29,564,713NCBIRnor6.0
Rnor_5.0429,477,846 - 29,478,037UniSTSRnor5.0
Rnor_5.0431,439,921 - 31,440,112UniSTSRnor5.0
RGSC_v3.4429,428,313 - 29,428,504UniSTSRGSC3.4
Celera427,982,399 - 27,982,590UniSTS
RH 3.4 Map4435.74UniSTS
Cytogenetic Map4q13UniSTS
RH133324  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2432,599,105 - 32,599,295 (+)MAPPERmRatBN7.2
Rnor_6.0431,569,390 - 31,569,579NCBIRnor6.0
Rnor_6.0429,565,019 - 29,565,208NCBIRnor6.0
Rnor_5.0431,440,418 - 31,440,607UniSTSRnor5.0
Rnor_5.0429,478,343 - 29,478,532UniSTSRnor5.0
RGSC_v3.4429,428,810 - 29,428,999UniSTSRGSC3.4
Celera427,982,896 - 27,983,085UniSTS
RH 3.4 Map4435.74UniSTS
Cytogenetic Map4q13UniSTS
AI179432  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8433,539,314 - 33,539,501 (+)Marker Load Pipeline
mRatBN7.2432,584,697 - 32,584,884 (+)MAPPERmRatBN7.2
Rnor_6.0429,550,612 - 29,550,798NCBIRnor6.0
Rnor_6.0431,554,983 - 31,555,169NCBIRnor6.0
Rnor_5.0431,426,011 - 31,426,197UniSTSRnor5.0
Rnor_5.0429,463,936 - 29,464,122UniSTSRnor5.0
RGSC_v3.4429,414,403 - 29,414,589UniSTSRGSC3.4
Celera427,968,577 - 27,968,763UniSTS
Cytogenetic Map4q13UniSTS
AA819207  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2432,597,337 - 32,598,521 (+)MAPPERmRatBN7.2
Rnor_6.0431,567,622 - 31,568,805NCBIRnor6.0
Rnor_6.0429,563,251 - 29,564,434NCBIRnor6.0
Rnor_5.0431,438,650 - 31,439,833UniSTSRnor5.0
Rnor_5.0429,476,575 - 29,477,758UniSTSRnor5.0
RGSC_v3.4429,427,042 - 29,428,225UniSTSRGSC3.4
Celera427,981,128 - 27,982,311UniSTS
RH 3.4 Map4219.24UniSTS
Cytogenetic Map4q13UniSTS
Col1a2  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2432,597,213 - 32,598,399 (+)MAPPERmRatBN7.2
Rnor_6.0431,567,498 - 31,568,683NCBIRnor6.0
Rnor_6.0429,563,127 - 29,564,312NCBIRnor6.0
Rnor_5.0429,476,451 - 29,477,636UniSTSRnor5.0
Rnor_5.0431,438,526 - 31,439,711UniSTSRnor5.0
RGSC_v3.4429,426,918 - 29,428,103UniSTSRGSC3.4
Celera427,981,004 - 27,982,189UniSTS
Cytogenetic Map4q13UniSTS
GDB:177260  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.07139,647,866 - 139,648,445NCBIRnor5.0
Rnor_5.0429,475,523 - 29,476,477NCBIRnor5.0
Rnor_5.0431,437,598 - 31,438,552NCBIRnor5.0
RGSC_v3.4429,425,991 - 29,426,944UniSTSRGSC3.4
RGSC_v3.47136,680,091 - 136,680,669UniSTSRGSC3.4
Celera427,980,077 - 27,981,030UniSTS
Celera7125,590,621 - 125,591,199UniSTS
Cytogenetic Map4q13UniSTS
Cytogenetic Map7q36UniSTS
GDB:180350  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8433,544,101 - 33,544,994 (+)Marker Load Pipeline
mRatBN7.2432,589,485 - 32,590,378 (+)MAPPERmRatBN7.2
Rnor_6.0429,555,399 - 29,556,291NCBIRnor6.0
Rnor_6.0431,559,770 - 31,560,662NCBIRnor6.0
Rnor_5.0431,430,798 - 31,431,690UniSTSRnor5.0
Rnor_5.0429,468,723 - 29,469,615UniSTSRnor5.0
RGSC_v3.4429,419,190 - 29,420,082UniSTSRGSC3.4
Celera427,973,363 - 27,974,255UniSTS
Cytogenetic Map4q13UniSTS
Col1a2  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2432,563,837 - 32,564,004 (+)MAPPERmRatBN7.2
Rnor_6.0431,534,125 - 31,534,291NCBIRnor6.0
Rnor_6.0429,529,754 - 29,529,920NCBIRnor6.0
Rnor_5.0429,443,078 - 29,443,244UniSTSRnor5.0
Rnor_5.0431,405,153 - 31,405,319UniSTSRnor5.0
RGSC_v3.4429,393,545 - 29,393,711UniSTSRGSC3.4
Celera427,947,792 - 27,947,958UniSTS
Cytogenetic Map4q13UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 9 45 82 67 69 45 15 45 6 176 79 66 37 56 24



Ensembl Acc Id: ENSRNOT00000016423   ⟹   ENSRNOP00000016423
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl432,563,381 - 32,598,867 (+)Ensembl
Rnor_6.0 Ensembl431,534,225 - 31,569,151 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000087619   ⟹   ENSRNOP00000073398
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl432,563,381 - 32,598,867 (+)Ensembl
Rnor_6.0 Ensembl429,535,852 - 29,564,768 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000089292   ⟹   ENSRNOP00000075459
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl431,534,225 - 31,568,806 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000089564   ⟹   ENSRNOP00000069327
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl429,529,854 - 29,564,435 (+)Ensembl
RefSeq Acc Id: NM_053356   ⟹   NP_445808
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8433,518,557 - 33,553,484 (+)NCBI
mRatBN7.2432,563,938 - 32,598,868 (+)NCBI
Rnor_6.0431,534,225 - 31,569,152 (+)NCBI
Rnor_5.0431,405,253 - 31,440,180 (+)NCBI
RGSC_v3.4429,393,645 - 29,428,572 (+)RGD
Celera427,947,892 - 27,982,658 (+)RGD
Sequence:
Protein RefSeqs NP_445808 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA40835 (Get FASTA)   NCBI Sequence Viewer  
  AAA40836 (Get FASTA)   NCBI Sequence Viewer  
  AAD41775 (Get FASTA)   NCBI Sequence Viewer  
  CAA46960 (Get FASTA)   NCBI Sequence Viewer  
  EDL84402 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000016423
GenBank Protein P02466 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_445808   ⟸   NM_053356
- Peptide Label: precursor
- UniProtKB: A0A0G2KAN1 (UniProtKB/TrEMBL),   F1LS40 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000075459   ⟸   ENSRNOT00000089292
Ensembl Acc Id: ENSRNOP00000016423   ⟸   ENSRNOT00000016423
Ensembl Acc Id: ENSRNOP00000073398   ⟸   ENSRNOT00000087619
Ensembl Acc Id: ENSRNOP00000069327   ⟸   ENSRNOT00000089564
Fibrillar collagen NC1

Name Modeler Protein Id AA Range Protein Structure
AF-P02466-F1-model_v2 AlphaFold P02466 1-1372 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 27 of 27 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-45721 BioCyc
Ensembl Genes ENSRNOG00000011292 Ensembl, ENTREZGENE
  ENSRNOG00000052925 Ensembl
Ensembl Transcript ENSRNOT00000016423 ENTREZGENE
Gene3D-CATH 2.60.120.1000 UniProtKB/Swiss-Prot
InterPro Collagen UniProtKB/Swiss-Prot
  Collagen_superfamily UniProtKB/Swiss-Prot
  Fib_collagen_C UniProtKB/Swiss-Prot
KEGG Report rno:84352 UniProtKB/Swiss-Prot
NCBI Gene 84352 ENTREZGENE
PANTHER COLLAGEN ALPHA UniProtKB/Swiss-Prot
  COLLAGEN TRIPLE HELIX REPEAT UniProtKB/Swiss-Prot
Pfam COLFI UniProtKB/Swiss-Prot
  Collagen UniProtKB/Swiss-Prot
PharmGKB COL1A2 RGD
PhenoGen Col1a2 PhenoGen
PROSITE NC1_FIB UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000011292 RatGTEx
  ENSRNOG00000052925 RatGTEx
SMART COLFI UniProtKB/Swiss-Prot
UniProt A0A0G2K5E8_RAT UniProtKB/TrEMBL
  A0A0G2KAN1 ENTREZGENE
  A6K2C0_RAT UniProtKB/TrEMBL
  CO1A2_RAT UniProtKB/Swiss-Prot
  F1LS40 ENTREZGENE, UniProtKB/TrEMBL
  P02466 ENTREZGENE
UniProt Secondary Q9R1E8 UniProtKB/Swiss-Prot
1 to 27 of 27 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Col1a2  collagen type I alpha 2 chain  NEWGENE_621351  collagen, type I, alpha 2  Data merged from RGD:9452897 737654 PROVISIONAL
2016-06-01 Col1a2  collagen type I alpha 2 chain  Col1a2  collagen, type I, alpha 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2014-08-25 NEWGENE_621351  collagen, type I, alpha 2      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-03-10 Col1a2  collagen, type I, alpha 2  Col1a2  procollagen, type I, alpha 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-12-14 Col1a2  procollagen, type I, alpha 2      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Col1a2  procollagen, type I, alpha 2      Symbol and Name status set to provisional 70820 PROVISIONAL

Note Type Note Reference
gene_regulation gene transcription was repressed by RFX1 625584
gene_transcript contains a binding site for the DNA methylation-responsive binding protein, regulatory factor for X-box 1 (RFX1) 625584