Nfyb (nuclear transcription factor Y subunit beta) - Rat Genome Database

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Gene: Nfyb (nuclear transcription factor Y subunit beta) Rattus norvegicus
Analyze
Symbol: Nfyb
Name: nuclear transcription factor Y subunit beta
RGD ID: 3172
Description: Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription factor binding activity; and sequence-specific DNA binding activity. Predicted to contribute to RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within cellular response to leukemia inhibitory factor and positive regulation of DNA-templated transcription. Part of CCAAT-binding activity factor complex. Orthologous to human NFYB (nuclear transcription factor Y subunit beta); PARTICIPATES IN altered p53 signaling pathway; antigen processing and presentation pathway; tuberculosis pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: CAAT box DNA-binding protein subunit B; CAAT-box DNA-binding protein subunit B; CBF-A; CBF-B; CBFB; CCAAT binding transcription factor of CBF-B/NFY-B; CCAAT-binding transcription factor subunit A; CCAAT-binding transcription factor subunit B; MGC108654; NF-YB; Nfya; nuclear transcription factor - Y beta; nuclear transcription factor Y subunit B; nuclear transcription factor-Y beta
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8722,852,543 - 22,868,116 (+)NCBIGRCr8
mRatBN7.2720,964,988 - 20,980,569 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl720,964,993 - 20,980,565 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx722,939,228 - 22,954,797 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0725,101,932 - 25,117,500 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0724,879,005 - 24,894,574 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0727,081,667 - 27,097,481 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl727,081,667 - 27,097,479 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0727,200,204 - 27,216,018 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4723,190,295 - 23,205,611 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1723,210,565 - 23,225,880 (+)NCBI
Celera718,145,883 - 18,161,286 (+)NCBICelera
Cytogenetic Map7q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


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Object Symbol
Species
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Original Reference(s)
NfybRat(-)-epigallocatechin 3-gallate multiple interactionsISONFYB (Homo sapiens)6480464[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of NFYB mRNACTDPMID:22079256
NfybRat(S)-nicotine decreases expressionISONFYB (Homo sapiens)6480464Nicotine results in decreased expression of NFYB mRNACTDPMID:18247414
NfybRat1,2-dichloroethane decreases expressionISONfyb (Mus musculus)6480464ethylene dichloride results in decreased expression of NFYB mRNACTDPMID:28189721 and PMID:28960355
NfybRat1,2-dimethylhydrazine decreases expressionISONfyb (Mus musculus)64804641 and 2-Dimethylhydrazine results in decreased expression of NFYB mRNACTDPMID:22206623
NfybRat17alpha-ethynylestradiol multiple interactionsISONfyb (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of NFYB mRNACTDPMID:17942748
NfybRat2,2',4,4',5,5'-hexachlorobiphenyl multiple interactionsISONfyb (Mus musculus)6480464[2 more ...CTDPMID:25510870
NfybRat2,2',5,5'-tetrachlorobiphenyl multiple interactionsISONfyb (Mus musculus)6480464[2 more ...CTDPMID:25510870
NfybRat2,3,7,8-tetrachlorodibenzodioxine affects expressionISONfyb (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of NFYB mRNACTDPMID:21570461 and PMID:24058054
NfybRat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of NFYB mRNACTDPMID:34747641
NfybRat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISONfyb (Mus musculus)6480464Tetrachlorodibenzodioxin results in decreased expression of NFYB mRNACTDPMID:16214954 more ...
NfybRat2,3,7,8-tetrachlorodibenzodioxine affects expressionEXP 6480464Tetrachlorodibenzodioxin affects the expression of NFYB mRNACTDPMID:22298810
NfybRat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of NFYB mRNACTDPMID:21215274 and PMID:33387578
NfybRat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISONfyb (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of NFYB mRNA more ...CTDPMID:16214954 more ...
NfybRat2,4-dinitrotoluene affects expressionEXP 64804642 and 4-dinitrotoluene affects the expression of NFYB mRNACTDPMID:21346803
NfybRat2,6-dinitrotoluene affects expressionEXP 64804642 and 6-dinitrotoluene affects the expression of NFYB mRNACTDPMID:21346803
NfybRat2-naphthylamine decreases expressionISONFYB (Homo sapiens)64804642-Naphthylamine results in decreased expression of NFYB mRNACTDPMID:18247414
NfybRat3,4-methylenedioxymethamphetamine increases methylationISONfyb (Mus musculus)6480464N-Methyl-3 and 4-methylenedioxyamphetamine results in increased methylation of NFYB promoterCTDPMID:26251327
NfybRat3,4-methylenedioxymethamphetamine decreases expressionISONfyb (Mus musculus)6480464N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of NFYB mRNACTDPMID:26251327
NfybRat3-isobutyl-1-methyl-7H-xanthine multiple interactionsISONFYB (Homo sapiens)6480464[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of NFYB mRNACTDPMID:28628672
NfybRat3H-1,2-dithiole-3-thione decreases expressionEXP 64804641 and 2-dithiol-3-thione results in decreased expression of NFYB mRNACTDPMID:19162173

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Biological Process
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Object Symbol
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Original Reference(s)
NfybRatcellular response to leukemia inhibitory factor acts_upstream_of_or_withinISONfyb (Mus musculus)1624291 PMID:20439489RGDPMID:20439489
NfybRatcellular response to leukemia inhibitory factor acts_upstream_of_or_withinIEAUniProtKB:P63139 and ensembl:ENSMUSP000001224031600115GO_REF:0000107EnsemblGO_REF:0000107
NfybRatpositive regulation of DNA-templated transcription acts_upstream_of_or_withinISONfyb (Mus musculus)1624291 PMID:15601870RGDPMID:15601870
NfybRatpositive regulation of DNA-templated transcription acts_upstream_of_or_withinIEAUniProtKB:P63139 and ensembl:ENSMUSP000001224031600115GO_REF:0000107EnsemblGO_REF:0000107
NfybRatpositive regulation of transcription by RNA polymerase II involved_inIEAGO:00012281600115GO_REF:0000108GOCGO_REF:0000108
NfybRatpositive regulation of transcription by RNA polymerase II involved_inIEAUniProtKB:P25208 and ensembl:ENSP000002400551600115GO_REF:0000107EnsemblGO_REF:0000107
NfybRatpositive regulation of transcription by RNA polymerase II involved_inISONFYB (Homo sapiens)1624291 PMID:11306579 and PMID:23332751RGDPMID:11306579 and PMID:23332751
NfybRatregulation of DNA-templated transcription involved_inISONFYB (Homo sapiens)1624291 PMID:15243141RGDPMID:15243141
NfybRatregulation of DNA-templated transcription involved_inIEAUniProtKB:P25208 and ensembl:ENSP000002400551600115GO_REF:0000107EnsemblGO_REF:0000107
NfybRatregulation of DNA-templated transcription involved_inIEAInterPro:IPR003956 and InterPro:IPR0271131600115GO_REF:0000002InterProGO_REF:0000002
NfybRatregulation of transcription by RNA polymerase II involved_inIBACGD:CAL0000175007 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
NfybRattranscription by RNA polymerase II  ICGO:0016602729287 RGD 
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Cellular Component
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Original Reference(s)
NfybRatCCAAT-binding factor complex  IDA 729287 RGD 
NfybRatCCAAT-binding factor complex part_ofIBAFB:FBgn0032816 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
NfybRatCCAAT-binding factor complex part_ofIEAInterPro:IPR0271131600115GO_REF:0000002InterProGO_REF:0000002
NfybRatCCAAT-binding factor complex part_ofISONFYB (Homo sapiens)1624291 PMID:15243141 and PMID:23332751RGDPMID:15243141 and PMID:23332751
NfybRatCCAAT-binding factor complex part_ofIEAUniProtKB:P25208 and ensembl:ENSP000002400551600115GO_REF:0000107EnsemblGO_REF:0000107
NfybRatnucleoplasm located_inTAS 1600115Reactome:R-RNO-9622586ReactomeReactome:R-RNO-9622586
NfybRatnucleoplasm located_inIEAUniProtKB:P25208 and ensembl:ENSP000002400551600115GO_REF:0000107EnsemblGO_REF:0000107
NfybRatnucleoplasm located_inISONFYB (Homo sapiens)1624291 RGDGO_REF:0000052
NfybRatnucleoplasm located_inTAS 1600115Reactome:R-RNO-9622571ReactomeReactome:R-RNO-9622571
NfybRatnucleus located_inISONFYB (Homo sapiens)1624291 PMID:11306579 more ...RGDPMID:11306579 more ...
NfybRatnucleus located_inIEAUniProtKB:P63139 and ensembl:ENSMUSP000001224031600115GO_REF:0000107EnsemblGO_REF:0000107
NfybRatnucleus located_inIEAUniProtKB-SubCell:SL-01911600115GO_REF:0000044UniProtGO_REF:0000044
NfybRatnucleus located_inIEAUniProtKB-KW:KW-05391600115GO_REF:0000043UniProtGO_REF:0000043
NfybRatnucleus located_inISONfyb (Mus musculus)1624291 PMID:19734906RGDPMID:19734906
NfybRatnucleus located_inIEAInterPro:IPR0039561600115GO_REF:0000002InterProGO_REF:0000002
NfybRatnucleus located_inIEAUniProtKB:P25208 and ensembl:ENSP000002400551600115GO_REF:0000107EnsemblGO_REF:0000107
NfybRatprotein-DNA complex part_ofISONFYB (Homo sapiens)1624291 PMID:11256944RGDPMID:11256944
NfybRatprotein-DNA complex part_ofIEAUniProtKB:P25208 and ensembl:ENSP000002400551600115GO_REF:0000107EnsemblGO_REF:0000107
NfybRatRNA polymerase II transcription regulator complex part_ofISONFYB (Homo sapiens)1624291 PMID:11256944RGDPMID:11256944
NfybRatRNA polymerase II transcription regulator complex part_ofIEAUniProtKB:P25208 and ensembl:ENSP000002400551600115GO_REF:0000107EnsemblGO_REF:0000107
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Molecular Function
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Object Symbol
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Original Reference(s)
NfybRatDNA binding enablesISONFYB (Homo sapiens)1624291 PMID:15243141RGDPMID:15243141
NfybRatDNA binding enablesIEAUniProtKB:P63139 and ensembl:ENSMUSP000001224031600115GO_REF:0000107EnsemblGO_REF:0000107
NfybRatDNA binding enablesIEAUniProtKB:P25208 and ensembl:ENSP000002400551600115GO_REF:0000107EnsemblGO_REF:0000107
NfybRatDNA binding enablesIEAUniProtKB-KW:KW-02381600115GO_REF:0000043UniProtGO_REF:0000043
NfybRatDNA binding enablesISONfyb (Mus musculus)1624291 PMID:15220343 and PMID:15601870RGDPMID:15220343 and PMID:15601870
NfybRatDNA-binding transcription activator activity, RNA polymerase II-specific enablesISONFYB (Homo sapiens)1624291UniProtKB:Q03701 and PMID:11306579RGDPMID:11306579
NfybRatDNA-binding transcription activator activity, RNA polymerase II-specific enablesIEAUniProtKB:P25208 and ensembl:ENSP000002400551600115GO_REF:0000107EnsemblGO_REF:0000107
NfybRatDNA-binding transcription activator activity, RNA polymerase II-specific enablesIEAInterPro:IPR0271131600115GO_REF:0000002InterProGO_REF:0000002
NfybRatDNA-binding transcription factor activity enablesISONfyb (Mus musculus)1624291 PMID:15601870RGDPMID:15601870
NfybRatDNA-binding transcription factor activity enablesIEAUniProtKB:P63139 and ensembl:ENSMUSP000001224031600115GO_REF:0000107EnsemblGO_REF:0000107
NfybRatDNA-binding transcription factor activity, RNA polymerase II-specific enablesIBAPANTHER:PTN000115646 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
NfybRatDNA-binding transcription factor binding enablesISONFYB (Homo sapiens)1624291UniProtKB:P06400 and PMID:19223331RGDPMID:19223331
NfybRatDNA-binding transcription factor binding enablesIEAUniProtKB:P25208 and ensembl:ENSP000002400551600115GO_REF:0000107EnsemblGO_REF:0000107
NfybRatprotein binding enablesISONFYB (Homo sapiens)1624291UniProtKB:P04637 more ...RGDPMID:12401788 more ...
NfybRatprotein heterodimerization activity enablesIEAInterPro:IPR0090721600115GO_REF:0000002InterProGO_REF:0000002
NfybRatprotein-containing complex binding  IDA 729287 RGD 
NfybRatRNA polymerase II cis-regulatory region sequence-specific DNA binding contributes_toISONFYB (Homo sapiens)1624291 PMID:11256944RGDPMID:11256944
NfybRatRNA polymerase II cis-regulatory region sequence-specific DNA binding contributes_toIBAPANTHER:PTN000115646 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
NfybRatRNA polymerase II cis-regulatory region sequence-specific DNA binding contributes_toIEAUniProtKB:P25208 and ensembl:ENSP000002400551600115GO_REF:0000107EnsemblGO_REF:0000107
NfybRatRNA polymerase II cis-regulatory region sequence-specific DNA binding enablesISONFYB (Homo sapiens)1624291 PMID:11306579RGDPMID:11306579
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RGD Manual Annotations


  
Object Symbol
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Reference
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Source
Original Reference(s)
NfybRataltered p53 signaling pathway   ISONFYB (Homo sapiens)8663430 RGD 
NfybRataltered p53 signaling pathway   ISONFYB (Homo sapiens)8663431 RGD 

Imported Annotations - KEGG (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
NfybRatantigen processing and presentation pathway  IEA 6907045 KEGGrno:04612
NfybRattuberculosis pathway  IEA 6907045 KEGGrno:05152

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#
Reference Title
Reference Citation
1. Mutant p53: one name, many proteins. Freed-Pastor WA and Prives C, Genes Dev. 2012 Jun 15;26(12):1268-86. doi: 10.1101/gad.190678.112.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. p53 mutations in cancer. Muller PA and Vousden KH, Nat Cell Biol. 2013 Jan;15(1):2-8. doi: 10.1038/ncb2641.
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. GOA pipeline RGD automated data pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Recombinant rat CBF-C, the third subunit of CBF/NFY, allows formation of a protein-DNA complex with CBF-A and CBF-B and with yeast HAP2 and HAP3. Sinha S, etal., Proc Natl Acad Sci U S A 1995 Feb 28;92(5):1624-8.
10. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
11. Purification and molecular cloning of the "A" chain of a rat heteromeric CCAAT-binding protein. Sequence identity with the yeast HAP3 transcription factor. Vuorio T, etal., J Biol Chem 1990 Dec 25;265(36):22480-6.
1 to 11 of 11 rows
PMID:1698608   PMID:11256944   PMID:12477932   PMID:15220343   PMID:15243141   PMID:15516209   PMID:15601870   PMID:15721292   PMID:15964792   PMID:18247329   PMID:19223331   PMID:19734906  
PMID:20439489  



Nfyb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8722,852,543 - 22,868,116 (+)NCBIGRCr8
mRatBN7.2720,964,988 - 20,980,569 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl720,964,993 - 20,980,565 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx722,939,228 - 22,954,797 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0725,101,932 - 25,117,500 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0724,879,005 - 24,894,574 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0727,081,667 - 27,097,481 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl727,081,667 - 27,097,479 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0727,200,204 - 27,216,018 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4723,190,295 - 23,205,611 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1723,210,565 - 23,225,880 (+)NCBI
Celera718,145,883 - 18,161,286 (+)NCBICelera
Cytogenetic Map7q13NCBI
NFYB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812104,117,086 - 104,138,210 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12104,117,086 - 104,138,241 (-)EnsemblGRCh38hg38GRCh38
GRCh3712104,510,864 - 104,531,988 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612103,034,988 - 103,056,170 (-)NCBINCBI36Build 36hg18NCBI36
Build 3412103,013,324 - 103,034,507NCBI
Celera12104,174,600 - 104,195,782 (-)NCBICelera
Cytogenetic Map12q23.3NCBI
HuRef12101,570,544 - 101,591,726 (-)NCBIHuRef
CHM1_112104,476,772 - 104,497,954 (-)NCBICHM1_1
T2T-CHM13v2.012104,078,781 - 104,099,908 (-)NCBIT2T-CHM13v2.0
Nfyb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391082,584,534 - 82,599,985 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1082,584,535 - 82,599,978 (-)EnsemblGRCm39 Ensembl
GRCm381082,748,700 - 82,764,151 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1082,748,701 - 82,764,144 (-)EnsemblGRCm38mm10GRCm38
MGSCv371082,211,445 - 82,226,886 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361082,178,499 - 82,193,940 (-)NCBIMGSCv36mm8
Celera1084,733,247 - 84,748,605 (-)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1040.25NCBI
Nfyb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540538,771,837 - 38,789,536 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540538,773,690 - 38,789,534 (-)NCBIChiLan1.0ChiLan1.0
NFYB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210112,179,923 - 112,200,452 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112112,176,320 - 112,196,849 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012101,693,559 - 101,714,057 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112105,089,028 - 105,108,825 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12105,089,028 - 105,108,825 (-)Ensemblpanpan1.1panPan2
NFYB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11542,608,067 - 42,628,816 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1542,609,606 - 42,629,158 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1542,977,178 - 42,998,767 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01543,265,789 - 43,287,387 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1543,264,430 - 43,286,300 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11542,531,537 - 42,553,082 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01542,630,397 - 42,651,973 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01542,901,800 - 42,923,377 (-)NCBIUU_Cfam_GSD_1.0
Nfyb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494517,348,997 - 17,368,049 (+)NCBIHiC_Itri_2
SpeTri2.0NW_00493649210,359,387 - 10,377,537 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NFYB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl580,334,748 - 80,353,768 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1580,333,762 - 80,353,466 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2583,903,195 - 83,922,952 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap5q2.3NCBI
NFYB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11199,320,263 - 99,341,289 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1199,319,390 - 99,329,726 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037145,655,097 - 145,678,182 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nfyb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247504,600,345 - 4,614,817 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247504,600,423 - 4,616,241 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Nfyb
67 total Variants

Predicted Target Of
Summary Value
Count of predictions:230
Count of miRNA genes:149
Interacting mature miRNAs:185
Transcripts:ENSRNOT00000066143
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 29 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1354644Spl4Serum phospholipid level QTL 44.9blood phospholipid amount (VT:0006084)blood phospholipid level (CMO:0001169)71965431749753746Rat
1300176Hrtrt10Heart rate QTL 103.19heart pumping trait (VT:2000009)heart rate (CMO:0000002)766427026029351Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)7532901950329019Rat
1578652Bmd15Bone mineral density QTL 155.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)7986646760460686Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7144822433Rat
10755438Coatc9Coat color QTL 90coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7352928048529280Rat
2298547Neuinf5Neuroinflammation QTL 53.7nervous system integrity trait (VT:0010566)spinal cord Cd74 protein level (CMO:0002131)7946224658265113Rat
10059592Kidm45Kidney mass QTL 453.950.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)7757398552573985Rat
2317047Wbc4White blood cell count QTL 40.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)7135342956Rat
10755440Coatc10Coat color QTL 100coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7749649952496499Rat

1 to 10 of 29 rows



alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000066143   ⟹   ENSRNOP00000061405
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl720,964,993 - 20,980,565 (+)Ensembl
Rnor_6.0 Ensembl727,081,667 - 27,097,479 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000082398   ⟹   ENSRNOP00000071810
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl720,972,271 - 20,979,287 (+)Ensembl
Rnor_6.0 Ensembl727,089,278 - 27,095,777 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000102116   ⟹   ENSRNOP00000095617
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl720,972,366 - 20,979,287 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000117282   ⟹   ENSRNOP00000091093
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl720,972,160 - 20,980,565 (+)Ensembl
RefSeq Acc Id: NM_031553   ⟹   NP_113741
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8722,852,546 - 22,868,116 (+)NCBI
mRatBN7.2720,964,999 - 20,980,569 (+)NCBI
Rnor_6.0727,081,667 - 27,097,481 (+)NCBI
Rnor_5.0727,200,204 - 27,216,018 (+)NCBI
RGSC_v3.4723,190,295 - 23,205,611 (+)RGD
Celera718,145,883 - 18,161,286 (+)RGD
Sequence:
RefSeq Acc Id: XM_039078461   ⟹   XP_038934389
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8722,852,728 - 22,868,116 (+)NCBI
mRatBN7.2720,965,529 - 20,980,569 (+)NCBI
RefSeq Acc Id: XM_039078462   ⟹   XP_038934390
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8722,852,543 - 22,868,116 (+)NCBI
mRatBN7.2720,964,988 - 20,980,569 (+)NCBI
RefSeq Acc Id: NP_113741   ⟸   NM_031553
- UniProtKB: Q5FVT0 (UniProtKB/Swiss-Prot),   P63140 (UniProtKB/Swiss-Prot),   A6IFH9 (UniProtKB/TrEMBL),   A0A0G2K1E6 (UniProtKB/TrEMBL),   A0A8I6B326 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000071810   ⟸   ENSRNOT00000082398
Ensembl Acc Id: ENSRNOP00000061405   ⟸   ENSRNOT00000066143
RefSeq Acc Id: XP_038934390   ⟸   XM_039078462
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038934389   ⟸   XM_039078461
- Peptide Label: isoform X1
- UniProtKB: P63140 (UniProtKB/Swiss-Prot),   Q5FVT0 (UniProtKB/Swiss-Prot),   A6IFH9 (UniProtKB/TrEMBL),   A0A0G2K1E6 (UniProtKB/TrEMBL),   A0A8I6B326 (UniProtKB/TrEMBL)
Transcription factor CBF/NF-Y/archaeal histone

Name Modeler Protein Id AA Range Protein Structure
AF-P63140-F1-model_v2 AlphaFold P63140 1-207 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13695111
Promoter ID:EPDNEW_R5636
Type:initiation region
Name:Nfyb_1
Description:nuclear transcription factor Y subunit beta
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0727,081,737 - 27,081,797EPDNEW


1 to 32 of 32 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-34550 BioCyc
Ensembl Genes ENSRNOG00000010309 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000066143 ENTREZGENE
  ENSRNOT00000066143.3 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.20.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7380395 IMAGE-MGC_LOAD
InterPro CBFA_NFYB_domain UniProtKB/Swiss-Prot
  Histone-fold UniProtKB/Swiss-Prot
  Transc_fact_NFYB/HAP3 UniProtKB/Swiss-Prot
  Transcrpt_fac_NFYB/HAP3_CS UniProtKB/Swiss-Prot
KEGG Report rno:25336 UniProtKB/Swiss-Prot
MGC_CLONE MGC:108654 IMAGE-MGC_LOAD
NCBI Gene 25336 ENTREZGENE
PANTHER NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT BETA UniProtKB/Swiss-Prot
  PTHR11064 UniProtKB/Swiss-Prot
Pfam CBFD_NFYB_HMF UniProtKB/Swiss-Prot
PhenoGen Nfyb PhenoGen
PRINTS CCAATSUBUNTA UniProtKB/Swiss-Prot
PROSITE NFYB_HAP3 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000010309 RatGTEx
Superfamily-SCOP SSF47113 UniProtKB/Swiss-Prot
TIGR TC209912
  TC223146
UniProt A0A0G2K1E6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AC92_RAT UniProtKB/TrEMBL
  A0A8I6B326 ENTREZGENE, UniProtKB/TrEMBL
  A6IFH9 ENTREZGENE, UniProtKB/TrEMBL
  A6IFI1_RAT UniProtKB/TrEMBL
  NFYB_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q5FVT0 ENTREZGENE
UniProt Secondary P22569 UniProtKB/Swiss-Prot
  Q5FVT0 UniProtKB/Swiss-Prot
1 to 32 of 32 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-20 Nfyb  nuclear transcription factor Y subunit beta  Nfyb  nuclear transcription factor-Y beta  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2001-07-23 Nfyb  CCAAT binding transcription factor of CBF-B/NFY-B      Name withdrawn 67952 WITHDRAWN
2001-07-23 Nfyb  nuclear transcription factor - Y beta      Name updated to reflect Human and Mouse nomenclature 67952 APPROVED

Note Type Note Reference
gene_protein 207 amino acids 728940