Acadvl (acyl-CoA dehydrogenase, very long chain) - Rat Genome Database

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Gene: Acadvl (acyl-CoA dehydrogenase, very long chain) Rattus norvegicus
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Symbol: Acadvl
Name: acyl-CoA dehydrogenase, very long chain
RGD ID: 2014
Description: Enables acyl-CoA dehydrogenase activity and heterocyclic compound binding activity. Involved in fatty acid beta-oxidation. Located in mitochondrial inner membrane. Biomarker of metabolic dysfunction-associated steatotic liver disease. Human ortholog(s) of this gene implicated in very long chain acyl-CoA dehydrogenase deficiency. Orthologous to human ACADVL (acyl-CoA dehydrogenase very long chain); PARTICIPATES IN fatty acid beta degradation pathway; carnitine palmitoyltransferase I deficiency pathway; ethylmalonic encephalopathy pathway; INTERACTS WITH 1,2,4-trimethylbenzene; 6-propyl-2-thiouracil; acetamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Acyl-Coa dehydrogenase Very long chain; acyl-Coenzyme A dehydrogenase, very long chain; MGC93660; Very long chain Acyl-Coa dehydrogenase; very long-chain specific acyl-CoA dehydrogenase, mitochondrial; VLCAD; VLCAD very-long-chain acyl-CoA dehydrogenase; VLCAD, very-long-chain acyl-CoA dehydrogenase
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81055,231,558 - 55,236,786 (-)NCBIGRCr8
mRatBN7.21054,732,875 - 54,738,102 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1054,732,469 - 54,738,075 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1059,395,021 - 59,400,168 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01058,883,601 - 58,888,748 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01054,390,891 - 54,396,038 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01056,619,321 - 56,624,468 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1056,619,303 - 56,624,526 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01056,364,440 - 56,369,587 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41056,856,233 - 56,861,380 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11056,869,857 - 56,875,003 (-)NCBI
Celera1053,886,459 - 53,891,606 (-)NCBICelera
Cytogenetic Map10q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
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Original Reference(s)
AcadvlRatAlzheimer's disease  ISORGD:73540710047114protein:decreased expression:brainRGD 
AcadvlRatExperimental Diabetes Mellitus  ISORGD:1005810047114protein:decreased expression:brainRGD 
AcadvlRatglutaric acidemia I  ISORGD:1005810047115 RGD 
AcadvlRatHeat Stress Disorders  IEP 8553966associated with EndotoxemiaRGD 
AcadvlRatmetabolic dysfunction-associated steatotic liver disease treatmentIEP 10047121 RGD 
AcadvlRatmetabolic dysfunction-associated steatotic liver disease treatmentIEP 10047124 RGD 
AcadvlRatMetabolic Syndrome treatmentIDA 10047118 RGD 
1 to 19 of 19 rows
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Original Reference(s)
AcadvlRatautism spectrum disorder  ISORGD:7354078554872ClinVar Annotator: match by term: Autism spectrum disorderClinVarPMID:30504930
AcadvlRatautosomal dominant intellectual developmental disorder 62  ISORGD:7354078554872ClinVar Annotator: match by term: DLG4-related condition | ClinVar Annotator: match by term: Intellectual developmental more ...ClinVarPMID:25741868|PMID:27618451
AcadvlRatCardiac Arrhythmias  ISORGD:7354078554872ClinVar Annotator: match by term: Cardiac arrhythmiaClinVarPMID:11590124|PMID:25741868|PMID:28492532|PMID:28755359|PMID:9973285
AcadvlRatcommon variable immunodeficiency  ISORGD:7354078554872ClinVar Annotator: match by term: Common variable immunodeficiencyClinVarPMID:28492532
AcadvlRatcongenital myasthenic syndrome 2A  ISORGD:7354078554872ClinVar Annotator: match by term: Congenital myasthenic syndrome 2AClinVarPMID:28492532
AcadvlRatdevelopmental and epileptic encephalopathy 25  ISORGD:7354078554872ClinVar Annotator: match by term: Developmental and epileptic encephalopathy, 25ClinVarPMID:28492532
AcadvlRatdilated cardiomyopathy  ISORGD:7354078554872ClinVar Annotator: match by term: Primary dilated cardiomyopathyClinVarPMID:18227065|PMID:21932095|PMID:25087612|PMID:25741868|PMID:26385305|PMID:27209629|PMID:28468868|PMID:28492532|PMID:31031081|PMID:34437764|PMID:35281659|PMID:9599005
AcadvlRatdyskeratosis congenita  ISORGD:7354078554872ClinVar Annotator: match by term: Dyskeratosis congenitaClinVarPMID:28492532
AcadvlRatfamilial hypertrophic cardiomyopathy  ISORGD:7354078554872ClinVar Annotator: match by term: Primary familial hypertrophic cardiomyopathyClinVar 
AcadvlRatFaundes-Banka Syndrome  ISORGD:7354078554872ClinVar Annotator: match by term: Faundes-Banka syndromeClinVarPMID:31690835
AcadvlRatgenetic disease  ISORGD:7354078554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:10077518|PMID:11590124|PMID:12208138|PMID:12213615|PMID:14517516|PMID:16860141|PMID:17374501|PMID:17576681|PMID:17999356|PMID:18227065|PMID:19208414|PMID:19327992|PMID:20107901|PMID:20301763|PMID:21429517|PMID:21932095|PMID:23169530|PMID:23418865|PMID:23430948|PMID:23480858|PMID:23798014|PMID:23867825|PMID:24033266|PMID:24503138|PMID:24801231|PMID:25087612|PMID:25214167|PMID:25741868|PMID:25843429|PMID:26385305|PMID:26743058|PMID:26937394|PMID:27209629|PMID:27246109|PMID:28468868|PMID:28492532|PMID:28518168|PMID:28747690|PMID:28755359|PMID:28871440|PMID:30194637|PMID:30504930|PMID:30904546|PMID:31031081|PMID:31589614|PMID:32054689|PMID:32061778|PMID:32461654|PMID:32518924|PMID:32710939|PMID:32778825|PMID:32928639|PMID:32954689|PMID:34106991|PMID:34194748|PMID:34437764|PMID:34564390|PMID:35267200|PMID:35281659|PMID:35281663|PMID:35400565|PMID:7479827|PMID:8739957|PMID:8845838|PMID:9536098|PMID:9599005|PMID:9973285
AcadvlRatintellectual disability  ISORGD:7354078554872ClinVar Annotator: match by term: Intellectual disability, mildClinVar 
AcadvlRatLi-Fraumeni syndrome  ISORGD:7354078554872ClinVar Annotator: match by term: Li-Fraumeni syndromeClinVarPMID:20522432|PMID:21056402|PMID:23172776|PMID:26681312|PMID:28492532
AcadvlRatmyopathy  ISORGD:7354078554872ClinVar Annotator: match by term: MyopathyClinVarPMID:14517516|PMID:19327992|PMID:20060901|PMID:21429517|PMID:23798014|PMID:25214167|PMID:25741868|PMID:26385305|PMID:28492532|PMID:30194637|PMID:30904546|PMID:31589614|PMID:32710939|PMID:34106991|PMID:9973285
AcadvlRatpancreatic hypoplasia-diabetes-congenital heart disease syndrome  ISORGD:7354078554872ClinVar Annotator: match by term: Pancreatic hypoplasia-diabetes-congenital heart disease syndromeClinVarPMID:25741868
AcadvlRatPearson syndrome  ISORGD:7354078554872ClinVar Annotator: match by term: Pearson syndromeClinVarPMID:25741868|PMID:28492532
AcadvlRatRhabdomyolysis  ISORGD:7354078554872ClinVar Annotator: match by term: RhabdomyolysisClinVarPMID:11158518|PMID:14517516|PMID:15210884|PMID:19327992|PMID:20060901|PMID:21429517|PMID:23798014|PMID:24801231|PMID:25214167|PMID:25741868|PMID:26385305|PMID:28492532|PMID:30194637|PMID:30904546|PMID:31589614|PMID:32581362|PMID:32710939|PMID:34106991|PMID:35400565|PMID:9546340|PMID:9973285
AcadvlRatvery long chain acyl-CoA dehydrogenase deficiency  ISORGD:7354078554872ClinVar Annotator: match by term: Very long chain acyl-CoA dehydrogenase deficiencyClinVarPMID:10077518|PMID:10384387|PMID:10431122|PMID:10518280|PMID:10529389|PMID:10738914|PMID:10790204|PMID:11158518|PMID:11349232|PMID:11590124|PMID:11914034|PMID:12122118|PMID:12208138|PMID:12213615|PMID:14517516|PMID:14728674|PMID:15210884|PMID:16199547|PMID:16435213|PMID:16443431|PMID:16464760|PMID:16488171|PMID:16860141|PMID:16895136|PMID:16950999|PMID:16982043|PMID:17206456|PMID:17374501|PMID:17514507|PMID:17576681|PMID:17999356|PMID:18227065|PMID:18414213|PMID:18670371|PMID:19208414|PMID:19327992|PMID:20056241|PMID:2006090|PMID:20060901|PMID:20107901|PMID:20301763|PMID:20480395|PMID:20547398|PMID:20694756|PMID:21228398|PMID:21378393|PMID:21429517|PMID:21531094|PMID:21814341|PMID:21932095|PMID:22494076|PMID:22841441|PMID:22847164|PMID:23169530|PMID:23418865|PMID:23430948|PMID:23430950|PMID:23480858|PMID:23700290|PMID:23757202|PMID:23774949|PMID:23798014|PMID:23867825|PMID:23966064|PMID:24033266|PMID:24263034|PMID:24305961|PMID:24503138|PMID:24801231|PMID:24898617|PMID:25085675|PMID:25087612|PMID:25214167|PMID:25242572|PMID:25338548|PMID:25456746|PMID:25525159|PMID:25652019|PMID:25655073|PMID:25737446|PMID:25741868|PMID:25834949|PMID:25843429|PMID:26182500|PMID:26385305|PMID:26453363|PMID:26602010|PMID:26743058|PMID:26881790|PMID:26927351|PMID:26937394|PMID:26982752|PMID:27029698|PMID:27209629|PMID:27246109|PMID:27538624|PMID:27884173|PMID:27943070|PMID:27995075|PMID:28468868|PMID:28492532|PMID:28518168|PMID:28600779|PMID:28747690|PMID:28755339|PMID:28755359|PMID:28871440|PMID:29111448|PMID:29268767|PMID:2951924|PMID:29519241|PMID:29552494|PMID:29768383|PMID:29961767|PMID:30023301|PMID:30194637|PMID:30904546|PMID:30950014|PMID:31031081|PMID:31191348|PMID:31497477|PMID:31589614|PMID:31620161|PMID:31737040|PMID:31794763|PMID:31983732|PMID:32054689|PMID:32061778|PMID:32276429|PMID:32380161|PMID:32461654|PMID:32518924|PMID:32558070|PMID:32581362|PMID:32655480|PMID:32669490|PMID:32710939|PMID:32778825|PMID:32793418|PMID:32798077|PMID:32860008|PMID:32928639|PMID:32954689|PMID:33123633|PMID:33150772|PMID:33549744|PMID:33610471|PMID:33965301|PMID:33986768|PMID:33996489|PMID:34106991|PMID:34184355|PMID:34194748|PMID:34426522|PMID:34437764|PMID:34480364|PMID:34485012|PMID:34564390|PMID:34704412|PMID:35095998|PMID:35193651|PMID:35218577|PMID:35267200|PMID:35281659|PMID:35281663|PMID:35400565|PMID:35626289|PMID:36078043|PMID:36109795|PMID:36356723|PMID:38015438|PMID:4022672|PMID:609575|PMID:7479827|PMID:7668252|PMID:7769092|PMID:8554073|PMID:8739957|PMID:8845838|PMID:9461620|PMID:9536098|PMID:9546340|PMID:9599005|PMID:9709714|PMID:9839948|PMID:9973285
AcadvlRatWeissenbacher-Zweymuller syndrome  ISORGD:7354078554872ClinVar Annotator: match by term: Glossoptosis, micrognathia, and cleft palateClinVar 
1 to 19 of 19 rows
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Original Reference(s)
AcadvlRatHypoxia  ISORGD:73540711554173CTD Direct Evidence: marker/mechanismCTDPMID:18258771
AcadvlRatvery long chain acyl-CoA dehydrogenase deficiency  ISORGD:73540711554173CTD Direct Evidence: marker/mechanismCTDPMID:20060901
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Original Reference(s)
AcadvlRatvery long chain acyl-CoA dehydrogenase deficiency  ISSRGD:1005813592920OMIM:201475MouseDO 
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Original Reference(s)
AcadvlRatvery long chain acyl-CoA dehydrogenase deficiency  ISORGD:7354077240710 OMIM 

1 to 20 of 163 rows

  
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Original Reference(s)
AcadvlRat1,2,4-trimethylbenzene decreases expressionEXP 6480464pseudocumene results in decreased expression of ACADVL proteinCTDPMID:17337753
AcadvlRat1,2-dimethylhydrazine decreases expressionISORGD:1005864804641,2-Dimethylhydrazine results in decreased expression of ACADVL mRNACTDPMID:22206623
AcadvlRat1,4-benzoquinone decreases expressionISORGD:7354076480464quinone results in decreased expression of ACADVL mRNACTDPMID:32478940
AcadvlRat17beta-estradiol decreases expressionISORGD:100586480464Estradiol results in decreased expression of ACADVL mRNACTDPMID:19484750
AcadvlRat17beta-estradiol increases expressionISORGD:100586480464Estradiol results in increased expression of ACADVL mRNACTDPMID:39298647
AcadvlRat2,2',4,4'-Tetrabromodiphenyl ether decreases expressionISORGD:1005864804642,2',4,4'-tetrabromodiphenyl ether results in decreased expression of ACADVL mRNACTDPMID:38040069
AcadvlRat2,2',5,5'-tetrachlorobiphenyl decreases expressionISORGD:73540764804642,5,2',5'-tetrachlorobiphenyl results in decreased expression of ACADVL mRNACTDPMID:36804509
AcadvlRat2,3,7,8-tetrachlorodibenzodioxine affects expressionISORGD:100586480464Tetrachlorodibenzodioxin affects the expression of ACADVL mRNACTDPMID:21570461
AcadvlRat2,3,7,8-tetrachlorodibenzodioxine increases expressionISORGD:7354076480464Tetrachlorodibenzodioxin results in increased expression of ACADVL mRNACTDPMID:11489354|PMID:20106945|PMID:21632981|PMID:21807756
AcadvlRat2,4-dibromophenyl 2,4,5-tribromophenyl ether affects expressionISORGD:1005864804642,2',4,4',5-brominated diphenyl ether affects the expression of ACADVL mRNACTDPMID:38648751
AcadvlRat2,6-dimethoxyphenol multiple interactionsISORGD:7354076480464[pyrogallol 1,3-dimethyl ether co-treated with Furaldehyde] results in increased expression of and affects the localization more ...CTDPMID:38598786
AcadvlRat2-palmitoylglycerol increases expressionISORGD:73540764804642-palmitoylglycerol results in increased expression of ACADVL mRNACTDPMID:37199045
AcadvlRat3-isobutyl-1-methyl-7H-xanthine multiple interactionsISORGD:100586480464[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of ACADVL mRNACTDPMID:23428407
AcadvlRat4,4'-sulfonyldiphenol increases expressionISORGD:100586480464bisphenol S results in increased expression of ACADVL mRNACTDPMID:39298647
AcadvlRat4,4'-sulfonyldiphenol increases expressionISORGD:7354076480464bisphenol S results in increased expression of ACADVL proteinCTDPMID:34186270
AcadvlRat4,4'-sulfonyldiphenol affects methylationISORGD:100586480464bisphenol S affects the methylation of ACADVL geneCTDPMID:31683443
AcadvlRat4-hydroxyphenyl retinamide increases expressionISORGD:7354076480464Fenretinide results in increased expression of ACADVL mRNACTDPMID:16671099
AcadvlRat4-hydroxyphenyl retinamide increases expressionISORGD:100586480464Fenretinide results in increased expression of ACADVL mRNACTDPMID:28973697
AcadvlRat5-aza-2'-deoxycytidine increases expressionISORGD:7354076480464Decitabine results in increased expression of ACADVL mRNACTDPMID:19151715
AcadvlRat6-propyl-2-thiouracil decreases expressionEXP 6480464Propylthiouracil results in decreased expression of ACADVL mRNACTDPMID:24780913

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Biological Process
1 to 20 of 24 rows

  
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Original Reference(s)
AcadvlRatcarboxylic acid catabolic process involved_inIEAARBA:ARBA000278821600115GO_REF:0000117UniProtGO_REF:0000117
AcadvlRatepithelial cell differentiation involved_inISORGD:7354071624291 PMID:21492153RGDPMID:21492153
AcadvlRatepithelial cell differentiation involved_inIEAUniProtKB:P49748|ensembl:ENSP000003492971600115GO_REF:0000107EnsemblGO_REF:0000107
AcadvlRatfatty acid beta-oxidation  IDA 631729 RGD 
AcadvlRatfatty acid beta-oxidation using acyl-CoA dehydrogenase involved_inIEAUniProtKB:P49748|ensembl:ENSP000003492971600115GO_REF:0000107EnsemblGO_REF:0000107
AcadvlRatfatty acid beta-oxidation using acyl-CoA dehydrogenase involved_inISORGD:100581624291 PMID:15639194RGDPMID:15639194
AcadvlRatfatty acid beta-oxidation using acyl-CoA dehydrogenase involved_inISORGD:7354071624291 PMID:7668252, PMID:9599005RGDPMID:7668252|PMID:9599005
AcadvlRatfatty acid beta-oxidation using acyl-CoA dehydrogenase involved_inISSUniProtKB:P497481600115GO_REF:0000024UniProtGO_REF:0000024
AcadvlRatfatty acid beta-oxidation using acyl-CoA dehydrogenase involved_inIEAUniProtKB:P50544|ensembl:ENSMUSP000000996341600115GO_REF:0000107EnsemblGO_REF:0000107
AcadvlRatfatty acid catabolic process acts_upstream_of_or_withinISORGD:100581624291MGI:3606688 PMID:21151927RGDPMID:21151927
AcadvlRatfatty acid catabolic process acts_upstream_of_or_withinIEAUniProtKB:P50544|ensembl:ENSMUSP000000996341600115GO_REF:0000107EnsemblGO_REF:0000107
AcadvlRatfatty acid metabolic process involved_inIEAARBA:ARBA000286691600115GO_REF:0000117UniProtGO_REF:0000117
AcadvlRatfatty acid metabolic process involved_inIEAUniProtKB-KW:KW-02761600115GO_REF:0000043UniProtGO_REF:0000043
AcadvlRatlipid metabolic process involved_inIEAUniProtKB-KW:KW-04431600115GO_REF:0000043UniProtGO_REF:0000043
AcadvlRatnegative regulation of fatty acid biosynthetic process involved_inIEAUniProtKB:P50544|ensembl:ENSMUSP000000996341600115GO_REF:0000107EnsemblGO_REF:0000107
AcadvlRatnegative regulation of fatty acid biosynthetic process involved_inISORGD:100581624291 PMID:15639194RGDPMID:15639194
AcadvlRatnegative regulation of fatty acid oxidation involved_inIEAUniProtKB:P50544|ensembl:ENSMUSP000000996341600115GO_REF:0000107EnsemblGO_REF:0000107
AcadvlRatnegative regulation of fatty acid oxidation involved_inISORGD:100581624291 PMID:15639194RGDPMID:15639194
AcadvlRatregulation of cholesterol metabolic process involved_inISORGD:100581624291 PMID:15639194RGDPMID:15639194
AcadvlRatregulation of cholesterol metabolic process involved_inIEAUniProtKB:P50544|ensembl:ENSMUSP000000996341600115GO_REF:0000107EnsemblGO_REF:0000107
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Cellular Component
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Original Reference(s)
AcadvlRatmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
AcadvlRatmitochondrial inner membrane  IDA 2317689 RGD 
AcadvlRatmitochondrial inner membrane located_inIEAUniProtKB-KW:KW-09991600115GO_REF:0000043UniProtGO_REF:0000043
AcadvlRatmitochondrial inner membrane located_inIEAUniProtKB-SubCell:SL-01681600115GO_REF:0000044UniProtGO_REF:0000044
AcadvlRatmitochondrial membrane located_inISORGD:7354071624291 PMID:16020546RGDPMID:16020546
AcadvlRatmitochondrial membrane located_inIEAUniProtKB:P49748|ensembl:ENSP000003492971600115GO_REF:0000107EnsemblGO_REF:0000107
AcadvlRatmitochondrial nucleoid located_inIEAUniProtKB:P49748|ensembl:ENSP000003492971600115GO_REF:0000107EnsemblGO_REF:0000107
AcadvlRatmitochondrial nucleoid located_inISORGD:7354071624291 PMID:18063578RGDPMID:18063578
AcadvlRatmitochondrion located_inIEAUniProtKB:P49748|ensembl:ENSP000003492971600115GO_REF:0000107EnsemblGO_REF:0000107
AcadvlRatmitochondrion located_inIEAUniProtKB-KW:KW-04961600115GO_REF:0000043UniProtGO_REF:0000043
AcadvlRatmitochondrion located_inISORGD:735407|UniProtKB:P49748-1|UniProtKB:P49748-2|UniProtKB:P49748-31624291 RGDGO_REF:0000052
AcadvlRatmitochondrion located_inISORGD:7354071624291 PMID:9461620RGDPMID:9461620
AcadvlRatnucleolus located_inISORGD:735407|UniProtKB:P49748-1|UniProtKB:P49748-2|UniProtKB:P49748-31624291 RGDGO_REF:0000052
AcadvlRatnucleolus located_inIEAUniProtKB:P49748|ensembl:ENSP000003492971600115GO_REF:0000107EnsemblGO_REF:0000107
AcadvlRatnucleoplasm located_inIEAUniProtKB:P49748|ensembl:ENSP000003492971600115GO_REF:0000107EnsemblGO_REF:0000107
AcadvlRatnucleoplasm located_inISORGD:735407|UniProtKB:P49748-1|UniProtKB:P49748-2|UniProtKB:P49748-31624291 RGDGO_REF:0000052
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Molecular Function
1 to 20 of 25 rows

  
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Original Reference(s)
AcadvlRatacyl-CoA dehydrogenase activity  IDA 631729 RGD 
AcadvlRatacyl-CoA dehydrogenase activity enablesIEAUniProtKB:P49748|ensembl:ENSP000003492971600115GO_REF:0000107EnsemblGO_REF:0000107
AcadvlRatacyl-CoA dehydrogenase activity enablesIEAInterPro:IPR0060891600115GO_REF:0000002InterProGO_REF:0000002
AcadvlRatacyl-CoA dehydrogenase activity enablesISORGD:7354071624291 PMID:9461620, PMID:9599005RGDPMID:9461620|PMID:9599005
AcadvlRatfatty-acyl-CoA binding  IDA 2317689 RGD 
AcadvlRatfatty-acyl-CoA binding enablesIBAPANTHER:PTN000856877|RGD:20141600115GO_REF:0000033GO_CentralGO_REF:0000033
AcadvlRatflavin adenine dinucleotide binding  IDA 2317689 RGD 
AcadvlRatflavin adenine dinucleotide binding enablesIEAInterPro:IPR013786|InterPro:IPR0370691600115GO_REF:0000002InterProGO_REF:0000002
AcadvlRatflavin adenine dinucleotide binding enablesIEAUniProtKB:P49748|ensembl:ENSP000003492971600115GO_REF:0000107EnsemblGO_REF:0000107
AcadvlRatflavin adenine dinucleotide binding enablesISORGD:7354071624291 PMID:9461620RGDPMID:9461620
AcadvlRatidentical protein binding enablesISSUniProtKB:P497481600115GO_REF:0000024UniProtGO_REF:0000024
AcadvlRatidentical protein binding enablesIEAUniProtKB:P49748|ensembl:ENSP000003492971600115GO_REF:0000107EnsemblGO_REF:0000107
AcadvlRatidentical protein binding enablesISORGD:7354071624291 PMID:9461620, PMID:9599005RGDPMID:9461620|PMID:9599005
AcadvlRatlong-chain fatty acyl-CoA dehydrogenase activity  IDA 631729 RGD 
AcadvlRatlong-chain fatty acyl-CoA dehydrogenase activity enablesISORGD:7354071624291 PMID:7668252RGDPMID:7668252
AcadvlRatlong-chain fatty acyl-CoA dehydrogenase activity enablesIEAUniProtKB:P49748|ensembl:ENSP000003492971600115GO_REF:0000107EnsemblGO_REF:0000107
AcadvlRatoxidoreductase activity enablesIEAUniProtKB-KW:KW-05601600115GO_REF:0000043UniProtGO_REF:0000043
AcadvlRatoxidoreductase activity, acting on the CH-CH group of donors enablesIEAInterPro:IPR006091|InterPro:IPR009075|InterPro:IPR009100|InterPro:IPR013786|InterPro:IPR036250|InterPro:IPR037069|InterPro:IPR0463731600115GO_REF:0000002InterProGO_REF:0000002
AcadvlRatprotein binding enablesISORGD:7354071624291UniProtKB:Q53T94 PMID:32296183RGDPMID:32296183
AcadvlRatvery-long-chain fatty acyl-CoA dehydrogenase activity  IDA 2317689 RGD 
1 to 20 of 25 rows

RGD Manual Annotations


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
AcadvlRatfatty acid beta degradation pathway   IMP 2317683 RGD 
AcadvlRatfatty acid beta degradation pathway   ISORGD:7354072317589 RGD 

Imported Annotations - SMPDB

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
AcadvlRatcarnitine palmitoyltransferase I deficiency pathway  ISORGD:73540710402751 SMPDBSMP:00538
AcadvlRatethylmalonic encephalopathy pathway  ISORGD:73540710402751 SMPDBSMP:00181
AcadvlRatfatty acid metabolic pathway  ISORGD:73540710402751 SMPDBSMP:00051
AcadvlRatglutaric aciduria type I pathway  ISORGD:73540710402751 SMPDBSMP:00185
AcadvlRatmedium chain acyl-CoA dehydrogenase deficiency pathway  ISORGD:73540710402751 SMPDBSMP:00542
AcadvlRatshort-chain acyl-CoA dehydrogenase deficiency pathway  ISORGD:73540710402751 SMPDBSMP:00235
AcadvlRattrifunctional protein deficiency pathway  ISORGD:73540710402751 SMPDBSMP:00545
AcadvlRatvery long-chain acyl-CoA dehydrogenase deficiency pathway  ISORGD:73540710402751 SMPDBSMP:00540

Imported Annotations - KEGG (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
AcadvlRatfatty acid metabolic pathway  IEA 6907045 KEGGrno:00071

Imported Annotations - PID (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
AcadvlRatforkhead class A signaling pathway  ISORGD:7354076484113 PIDPID:200087

1 to 20 of 27 rows
#
Reference Title
Reference Citation
1. Rat very-long-chain acyl-CoA dehydrogenase, a novel mitochondrial acyl-CoA dehydrogenase gene product, is a rate-limiting enzyme in long-chain fatty acid beta-oxidation system. cDNA and deduced amino acid sequence and distinct specificities of the cDNA-expressed protein. Aoyama T, etal., J Biol Chem 1994 Jul 22;269(29):19088-94.
2. Rozhledy v chirurgii : mesícník Ceskoslovenské chirurgické spolecnosti Bana J and Kralik J, Rozhl Chir 1978 Dec;57(12):813-20.
3. [A rare type of bone involvement in scleroderma (author's transl)] Bem Z and Birecka A, Pol Przegl Radiol Med Nukl 1978 Mar-Apr;42(2):115-7.
4. Potential roles of PINK1 for increased PGC-1alpha-mediated mitochondrial fatty acid oxidation and their associations with Alzheimer disease and diabetes. Choi J, etal., Mitochondrion. 2014 Sep;18:41-8. doi: 10.1016/j.mito.2014.09.005. Epub 2014 Sep 23.
5. Identification of S-nitrosated mitochondrial proteins by S-nitrosothiol difference in gel electrophoresis (SNO-DIGE): implications for the regulation of mitochondrial function by reversible S-nitrosation. Chouchani ET, etal., Biochem J. 2010 Aug 15;430(1):49-59. doi: 10.1042/BJ20100633.
6. Asperuloside stimulates metabolic function in rats across several organs under high-fat diet conditions, acting like the major ingredient of Eucommia leaves with anti-obesity activity. Fujikawa T, etal., J Nutr Sci. 2012 Sep 5;1:e10. doi: 10.1017/jns.2012.12. eCollection 2012.
7. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
8. Acyl-CoA dehydrogenases. A mechanistic overview. Ghisla S and Thorpe C, Eur J Biochem. 2004 Feb;271(3):494-508.
9. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
10. Novel fatty acid beta-oxidation enzymes in rat liver mitochondria. I. Purification and properties of very-long-chain acyl-coenzyme A dehydrogenase. Izai K, etal., J Biol Chem. 1992 Jan 15;267(2):1027-33.
11. The modulation of hepatic adenosine triphosphate and inflammation by eicosapentaenoic acid during severe fibrotic progression in the SHRSP5/Dmcr rat model. Jia X, etal., Life Sci. 2012 Jun 14;90(23-24):934-43. doi: 10.1016/j.lfs.2012.04.029. Epub 2012 Apr 30.
12. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
13. Selenium significantly inhibits adipocyte hypertrophy and abdominal fat accumulation in OLETF rats via induction of fatty acid beta-oxidation. Kim JE, etal., Biol Trace Elem Res. 2012 Dec;150(1-3):360-70. doi: 10.1007/s12011-012-9519-1. Epub 2012 Oct 18.
14. Inhibition of very long chain acyl-CoA dehydrogenase during cardiac ischemia. Mason KE, etal., Arch Biochem Biophys. 2005 May 15;437(2):138-43. Epub 2005 Mar 19.
15. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
16. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
17. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
18. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
19. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
20. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
1 to 20 of 27 rows
PMID:7668252   PMID:12477932   PMID:14651853   PMID:15639194   PMID:16020546   PMID:18063578   PMID:18614015   PMID:21151927   PMID:21492153   PMID:26316108   PMID:26945066  



Acadvl
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81055,231,558 - 55,236,786 (-)NCBIGRCr8
mRatBN7.21054,732,875 - 54,738,102 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1054,732,469 - 54,738,075 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1059,395,021 - 59,400,168 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01058,883,601 - 58,888,748 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01054,390,891 - 54,396,038 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01056,619,321 - 56,624,468 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1056,619,303 - 56,624,526 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01056,364,440 - 56,369,587 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41056,856,233 - 56,861,380 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11056,869,857 - 56,875,003 (-)NCBI
Celera1053,886,459 - 53,891,606 (-)NCBICelera
Cytogenetic Map10q24NCBI
ACADVL
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38177,217,125 - 7,225,266 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl177,217,125 - 7,225,266 (+)EnsemblGRCh38hg38GRCh38
GRCh37177,120,444 - 7,128,585 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36177,063,877 - 7,069,309 (+)NCBINCBI36Build 36hg18NCBI36
Build 34177,063,956 - 7,069,306NCBI
Celera177,147,787 - 7,153,219 (+)NCBICelera
Cytogenetic Map17p13.1NCBI
HuRef177,012,512 - 7,020,576 (+)NCBIHuRef
CHM1_1177,129,209 - 7,137,334 (+)NCBICHM1_1
T2T-CHM13v2.0177,118,036 - 7,126,177 (+)NCBIT2T-CHM13v2.0
Acadvl
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391169,901,009 - 69,906,254 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1169,901,009 - 69,906,237 (-)EnsemblGRCm39 Ensembl
GRCm381170,010,183 - 70,015,428 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1170,010,183 - 70,015,411 (-)EnsemblGRCm38mm10GRCm38
MGSCv371169,823,694 - 69,828,909 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361169,826,387 - 69,831,602 (-)NCBIMGSCv36mm8
Celera1177,558,144 - 77,563,359 (-)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1142.96NCBI
Acadvl
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554679,684,250 - 9,689,356 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554679,684,070 - 9,689,454 (-)NCBIChiLan1.0ChiLan1.0
ACADVL
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21914,812,517 - 14,817,937 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11716,778,578 - 16,783,944 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0177,249,717 - 7,255,165 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1177,236,286 - 7,242,417 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl177,234,283 - 7,242,417 (+)Ensemblpanpan1.1panPan2
ACADVL
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1532,189,191 - 32,194,255 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl532,186,502 - 32,327,990 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha532,327,393 - 32,332,562 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0532,294,698 - 32,299,874 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl532,292,139 - 32,335,711 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1532,260,008 - 32,265,180 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0532,219,055 - 32,224,215 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0532,395,976 - 32,401,145 (+)NCBIUU_Cfam_GSD_1.0
Acadvl
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560247,040,681 - 47,046,036 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936595514,534 - 520,223 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936595514,883 - 520,223 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ACADVL
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1252,576,402 - 52,581,748 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11252,573,521 - 52,581,755 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23139,851,936 - 139,857,148 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ACADVL
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1166,593,288 - 6,598,980 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl166,593,287 - 6,598,979 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605914,811,795 - 14,817,522 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Acadvl
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247869,838,227 - 9,843,332 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247869,838,102 - 9,843,506 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Acadvl
10 total Variants

Predicted Target Of
Summary Value
Count of predictions:53
Count of miRNA genes:51
Interacting mature miRNAs:53
Transcripts:ENSRNOT00000024973
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 76 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
61441Btemp1Thermal response to stress QTL 14body temperature trait (VT:0005535)core body temperature (CMO:0001036)103539245763642539Rat
1549846Scl47Serum cholesterol level QTL 473.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)105057470795574707Rat
9589136Insul27Insulin level QTL 2710.460.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)101147401056474010Rat
152025229Scl83Serum cholesterol level QTL 834.33blood cholesterol amount (VT:0000180)103571058068663659Rat
1578779Tcas10Tongue tumor susceptibility QTL 103.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)103129743976297439Rat
152025227Bw195Body weight QTL 1955.73body mass (VT:0001259)104698969968663659Rat
631564Apr3Acute phase response QTL 33.9blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)101527595560275955Rat
1298069Bp168Blood pressure QTL 1685.5blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)102652195798003205Rat
2293669Bmd33Bone mineral density QTL 334.50.0001femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)104944455181709989Rat
152025224Bw193Body weight QTL 1936.47body mass (VT:0001259)105166340575085664Rat

1 to 10 of 76 rows



alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000024973   ⟹   ENSRNOP00000024973
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1054,732,469 - 54,738,075 (-)Ensembl
Rnor_6.0 Ensembl1056,619,303 - 56,624,526 (-)Ensembl
RefSeq Acc Id: NM_012891   ⟹   NP_037023
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81055,231,558 - 55,236,705 (-)NCBI
mRatBN7.21054,732,875 - 54,738,022 (-)NCBI
Rnor_6.01056,619,321 - 56,624,468 (-)NCBI
Rnor_5.01056,364,440 - 56,369,587 (-)NCBI
RGSC_v3.41056,856,233 - 56,861,380 (-)RGD
Celera1053,886,459 - 53,891,606 (-)RGD
Sequence:
RefSeq Acc Id: XM_063268458   ⟹   XP_063124528
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81055,233,882 - 55,236,786 (-)NCBI
1 to 10 of 10 rows
Protein RefSeqs NP_037023 (Get FASTA)   NCBI Sequence Viewer  
  XP_063124528 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH87036 (Get FASTA)   NCBI Sequence Viewer  
  BAA06331 (Get FASTA)   NCBI Sequence Viewer  
  EDM04962 (Get FASTA)   NCBI Sequence Viewer  
  EDM04963 (Get FASTA)   NCBI Sequence Viewer  
  EDM04964 (Get FASTA)   NCBI Sequence Viewer  
  EDM04965 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000024973
GenBank Protein P45953 (Get FASTA)   NCBI Sequence Viewer  
1 to 10 of 10 rows
RefSeq Acc Id: NP_037023   ⟸   NM_012891
- Peptide Label: precursor
- UniProtKB: P45953 (UniProtKB/Swiss-Prot),   F7FEX1 (UniProtKB/TrEMBL),   Q5M9H2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000024973   ⟸   ENSRNOT00000024973
RefSeq Acc Id: XP_063124528   ⟸   XM_063268458
- Peptide Label: isoform X1
ACAD9/ACADV-like C-terminal   Acyl-CoA dehydrogenase/oxidase C-terminal   Acyl-CoA dehydrogenase/oxidase N-terminal   Acyl-CoA oxidase/dehydrogenase middle

Name Modeler Protein Id AA Range Protein Structure
AF-P45953-F1-model_v2 AlphaFold P45953 1-655 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13697345
Promoter ID:EPDNEW_R7870
Type:initiation region
Name:Acadvl_1
Description:acyl-CoA dehydrogenase, very long chain
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01056,624,517 - 56,624,577EPDNEW


1 to 40 of 40 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-24489 BioCyc
Ensembl Genes ENSRNOG00000018114 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000024973 ENTREZGENE
Gene3D-CATH 1.10.540.10 UniProtKB/Swiss-Prot
  2.40.110.10 UniProtKB/Swiss-Prot
  Butyryl-CoA Dehydrogenase, subunit A, domain 3 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7193535 IMAGE-MGC_LOAD
InterPro ACAD9/ACADV-like_C UniProtKB/Swiss-Prot
  Acyl-CoA_DH_CS UniProtKB/Swiss-Prot
  Acyl-CoA_Oxase/DH_cen-dom UniProtKB/Swiss-Prot
  Acyl-CoA_Oxase/DH_mid-dom_sf UniProtKB/Swiss-Prot
  AcylCo_DH-like_C UniProtKB/Swiss-Prot
  AcylCo_DH/oxidase_C UniProtKB/Swiss-Prot
  AcylCoA_DH/ox_N UniProtKB/Swiss-Prot
  AcylCoA_DH/ox_N_sf UniProtKB/Swiss-Prot
  AcylCoA_DH/oxidase_NM_dom UniProtKB/Swiss-Prot
KEGG Report rno:25363 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93660 IMAGE-MGC_LOAD
NCBI Gene 25363 ENTREZGENE
PANTHER ACYL-COA DEHYDROGENASE UniProtKB/Swiss-Prot
  VERY LONG-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL UniProtKB/Swiss-Prot
Pfam ACAD9-ACADV_C UniProtKB/Swiss-Prot
  Acyl-CoA_dh_1 UniProtKB/Swiss-Prot
  Acyl-CoA_dh_M UniProtKB/Swiss-Prot
  Acyl-CoA_dh_N UniProtKB/Swiss-Prot
PharmGKB ACADVL RGD
PhenoGen Acadvl PhenoGen
PROSITE ACYL_COA_DH_1 UniProtKB/Swiss-Prot
  ACYL_COA_DH_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000018114 RatGTEx
Superfamily-SCOP SSF47203 UniProtKB/Swiss-Prot
  SSF56645 UniProtKB/Swiss-Prot
TIGR TC217112
UniProt A6HG07_RAT UniProtKB/TrEMBL
  A6HG08_RAT UniProtKB/TrEMBL
  A6HG10_RAT UniProtKB/TrEMBL
  ACADV_RAT UniProtKB/Swiss-Prot
  F7FEX1 ENTREZGENE, UniProtKB/TrEMBL
  P45953 ENTREZGENE
  Q5M9H2 ENTREZGENE, UniProtKB/TrEMBL
1 to 40 of 40 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-07-28 Acadvl  acyl-CoA dehydrogenase, very long chain  Acadvl  acyl-Coenzyme A dehydrogenase, very long chain  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2003-04-09 Acadvl  acyl-Coenzyme A dehydrogenase, very long chain    Acyl-Coa dehydrogenase, Very long chain  Name updated 629478 APPROVED
2002-06-10 Acadvl  Acyl-Coa dehydrogenase, Very long chain      Symbol and Name status set to approved 70586 APPROVED

Note Type Note Reference
gene_cellular_localization localized to mitochondria 631729
gene_function catalyzes the beta-oxidation of long-chain fatty acids 631729
gene_process plays a role in long chain fatty acid metabolism 631729
gene_product member of the acyl-CoA dehydrogenase family 631729
gene_protein 655 amino acid sequence with 40 amino acid leader sequence and 615 amino acid residues in the mature protein 631729