Acadvl (acyl-CoA dehydrogenase very long chain) - Rat Genome Database

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Gene: Acadvl (acyl-CoA dehydrogenase very long chain) Heterocephalus glaber
Analyze
Symbol: Acadvl
Name: acyl-CoA dehydrogenase very long chain
RGD ID: 18926731
Description: ENCODES a protein that exhibits acyl-CoA dehydrogenase activity (ortholog); fatty-acyl-CoA binding (ortholog); flavin adenine dinucleotide binding (ortholog); INVOLVED IN epithelial cell differentiation (ortholog); fatty acid beta-oxidation (ortholog); fatty acid beta-oxidation using acyl-CoA dehydrogenase (ortholog); PARTICIPATES IN carnitine palmitoyltransferase I deficiency pathway; ethylmalonic encephalopathy pathway; fatty acid beta degradation pathway; ASSOCIATED WITH acute myeloid leukemia (ortholog); Alzheimer's disease (ortholog); atrial heart septal defect (ortholog); FOUND IN mitochondrial inner membrane (ortholog); mitochondrial membrane (ortholog); mitochondrial nucleoid (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: very long-chain specific acyl-CoA dehydrogenase, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247869,838,102 - 9,843,506 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
HetGla_female_1.0 EnsemblNW_0046247869,838,227 - 9,843,332 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
Naked mole-rat maternal Ensembl2056,623,619 - 56,629,750 (+)Ensembl
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Acadvl
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247869,838,102 - 9,843,506 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
HetGla_female_1.0 EnsemblNW_0046247869,838,227 - 9,843,332 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
Naked mole-rat maternal Ensembl2056,623,619 - 56,629,750 (+)Ensembl
ACADVL
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38177,217,125 - 7,225,266 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl177,217,125 - 7,225,273 (+)EnsemblGRCh38.p14 Ensemblhg38GRCh38
GRCh37177,120,444 - 7,128,585 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36177,063,877 - 7,069,309 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34177,063,956 - 7,069,306NCBI
Celera177,147,787 - 7,153,219 (+)NCBICelera
Cytogenetic Map17p13.1NCBI
HuRef177,012,512 - 7,020,576 (+)NCBIHuRef
CHM1_1177,129,209 - 7,137,334 (+)NCBICHM1_1
T2T-CHM13v2.0177,118,036 - 7,126,177 (+)NCBIT2T-CHM13v2.0
Acadvl
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391169,901,009 - 69,906,254 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1169,900,853 - 69,906,270 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381170,010,183 - 70,015,428 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1170,010,183 - 70,015,411 (-)EnsemblGRCm38.p6 Ensemblmm10GRCm38
MGSCv371169,823,694 - 69,828,909 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361169,826,387 - 69,831,602 (-)NCBIMGSCv36mm8
Celera1177,558,144 - 77,563,359 (-)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1142.96NCBI
Acadvl
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81055,231,558 - 55,236,786 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1055,231,440 - 55,236,750 (-)EnsemblGRCr8
mRatBN7.21054,732,875 - 54,738,102 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1054,732,469 - 54,738,075 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1059,395,021 - 59,400,168 (-)NCBIUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01058,883,601 - 58,888,748 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01054,390,891 - 54,396,038 (-)NCBIUTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd1058,173,081 - 58,178,228 (-)NCBI
Lyon_Normotensive1058,829,998 - 58,835,145 (-)NCBI
Lyon_Hypertensive1060,498,066 - 60,503,213 (-)NCBI
F344_StmMcwi1060,412,248 - 60,417,395 (-)NCBI
Rnor_6.01056,619,321 - 56,624,468 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1056,619,303 - 56,624,526 (-)EnsemblRnor_6.0 Ensemblrn6Rnor6.0
Rnor_5.01056,364,440 - 56,369,587 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41056,856,233 - 56,861,380 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1053,886,459 - 53,891,606 (-)NCBICelera
RGSC_v3.11056,869,857 - 56,875,003 (-)NCBI
Cytogenetic Map10q24NCBI
Acadvl
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554679,684,250 - 9,689,356 (-)EnsemblChiLan1.0 Ensembl
ChiLan1.0NW_0049554679,684,070 - 9,689,454 (-)NCBIChiLan1.0ChiLan1.0
ACADVL
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21914,812,517 - 14,817,937 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11716,778,578 - 16,783,944 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0177,249,717 - 7,255,165 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1177,236,286 - 7,242,417 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl177,234,283 - 7,242,417 (+)EnsemblPanPan1.1 EnsemblpanPan2panpan1.1
ACADVL
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1532,189,191 - 32,194,255 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl532,186,502 - 32,327,990 (+)EnsemblCanFam3.1 EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha532,327,393 - 32,332,562 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0532,294,698 - 32,299,874 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl532,292,139 - 32,335,711 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1532,260,008 - 32,265,180 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0532,219,055 - 32,224,215 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0532,395,976 - 32,401,145 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Acadvl
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mIctTri1.hap1351,562,121 - 51,567,466 (+)NCBImIctTri1.hap1
HiC_Itri_2NW_02440560247,040,681 - 47,046,036 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936595514,534 - 520,223 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936595514,883 - 520,223 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ACADVL
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1252,576,402 - 52,581,748 (+)EnsemblSscrofa11.1 EnsemblsusScr11Sscrofa11.1
Sscrofa11.11252,573,521 - 52,581,755 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23139,851,936 - 139,857,148 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ACADVL
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mChlSab1.0.hap1167,057,579 - 7,063,219 (+)NCBImChlSab1.0.hap1
Vero_WHO_p1.0NW_02366605914,811,795 - 14,817,522 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
ChlSab1.1166,593,288 - 6,598,980 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl166,593,287 - 6,598,979 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Acadvl
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1949,616,754 - 49,621,945 (-)NCBIRrattus_CSIRO_v1Rrattus_CSIRO_v1


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000015571   ⟹   ENSHGLP00000015411
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247869,838,227 - 9,843,332 (+)Ensembl
Naked mole-rat maternal Ensembl2056,623,619 - 56,629,750 (+)Ensembl
Ensembl Acc Id: ENSHGLT00000015572   ⟹   ENSHGLP00000015412
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247869,838,227 - 9,843,332 (+)Ensembl
Naked mole-rat maternal Ensembl2056,623,619 - 56,629,750 (+)Ensembl
RefSeq Acc Id: XM_013076822   ⟹   XP_012932276
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247869,838,102 - 9,843,506 (+)NCBI
RefSeq Acc Id: XM_021238497   ⟹   XP_021094156
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247869,838,102 - 9,843,506 (+)NCBI
RefSeq Acc Id: XR_002387004
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247869,838,102 - 9,843,506 (+)NCBI
Protein Sequences
Protein RefSeqs XP_012932276 (Get FASTA)   NCBI Sequence Viewer  
  XP_021094156 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000015411
GenBank Protein JAN99477 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_012932276   ⟸   XM_013076822
- Peptide Label: isoform X1
- UniProtKB: A0AAX6R0L4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021094156   ⟸   XM_021238497
- Peptide Label: isoform X2
- UniProtKB: A0AAX6RBA0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000015411   ⟸   ENSHGLT00000015571
Ensembl Acc Id: ENSHGLP00000015412   ⟸   ENSHGLT00000015572


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000011018 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000015571 ENTREZGENE
Gene3D-CATH 1.10.540.10 UniProtKB/TrEMBL
  2.40.110.10 UniProtKB/TrEMBL
  Butyryl-CoA Dehydrogenase, subunit A, domain 3 UniProtKB/TrEMBL
InterPro ACAD9/ACADV-like_C UniProtKB/TrEMBL
  Acyl-CoA_DH_CS UniProtKB/TrEMBL
  Acyl-CoA_Oxase/DH_cen-dom UniProtKB/TrEMBL
  Acyl-CoA_Oxase/DH_mid-dom_sf UniProtKB/TrEMBL
  AcylCo_DH-like_C UniProtKB/TrEMBL
  AcylCo_DH/oxidase_C UniProtKB/TrEMBL
  AcylCoA_DH/ox_N UniProtKB/TrEMBL
  AcylCoA_DH/ox_N_sf UniProtKB/TrEMBL
  AcylCoA_DH/oxidase_NM_dom UniProtKB/TrEMBL
KEGG Report hgl:101707761 UniProtKB/TrEMBL
NCBI Gene Acadvl ENTREZGENE
PANTHER ACYL-COA DEHYDROGENASE UniProtKB/TrEMBL
  VERY LONG-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL UniProtKB/TrEMBL
Pfam ACAD9-ACADV_C UniProtKB/TrEMBL
  Acyl-CoA_dh_1 UniProtKB/TrEMBL
  Acyl-CoA_dh_M UniProtKB/TrEMBL
  Acyl-CoA_dh_N UniProtKB/TrEMBL
PROSITE ACYL_COA_DH_1 UniProtKB/TrEMBL
  ACYL_COA_DH_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF47203 UniProtKB/TrEMBL
  SSF56645 UniProtKB/TrEMBL
UniProt A0AAX6R0L4 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6RBA0 ENTREZGENE, UniProtKB/TrEMBL