Trps1 (transcriptional repressor GATA binding 1) - Rat Genome Database

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Gene: Trps1 (transcriptional repressor GATA binding 1) Rattus norvegicus
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Symbol: Trps1
Name: transcriptional repressor GATA binding 1
RGD ID: 1311883
Description: Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and protein domain specific binding activity. Predicted to be involved in several processes, including hair follicle development; negative regulation of transcription by RNA polymerase II; and regulation of chondrocyte differentiation. Predicted to act upstream of or within several processes, including cell surface receptor protein serine/threonine kinase signaling pathway; chondrocyte differentiation; and positive regulation of extrinsic apoptotic signaling pathway via death domain receptors. Predicted to be located in chromatin and nucleoplasm. Predicted to be part of protein-containing complex. Human ortholog(s) of this gene implicated in osteochondrodysplasia; trichorhinophalangeal syndrome type I; and trichorhinophalangeal syndrome type III. Orthologous to human TRPS1 (transcriptional repressor GATA binding 1); INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; 3,4-methylenedioxymethamphetamine; acetamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC299897; trichorhinophalangeal syndrome I; trichorhinophalangeal syndrome I (human); trichorhinophalangeal syndrome I homolog; trichorhinophalangeal syndrome I homolog (human); zinc finger transcription factor Trps1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8783,806,121 - 84,032,609 (-)NCBIGRCr8
mRatBN7.2781,916,668 - 82,142,733 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl781,921,601 - 82,141,905 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx783,803,208 - 84,022,882 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0786,005,758 - 86,225,442 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0785,848,280 - 86,067,966 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0790,085,895 - 90,320,430 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl790,090,828 - 90,318,221 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0790,113,508 - 90,343,325 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4786,855,378 - 87,076,668 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1786,876,430 - 87,097,949 (-)NCBI
Celera778,810,727 - 79,029,498 (-)NCBICelera
Cytogenetic Map7q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Trps1Ratosteochondrodysplasia  ISOTRPS1 (Homo sapiens)1599670trichorhinophalangeal syndrome type I and OMIM:190350RGD 
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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Trps1Ratbrachydactyly  ISOTRPS1 (Homo sapiens)8554872ClinVar Annotator: match by term: BrachydactylyClinVarPMID:11112658 more ...
Trps1RatCAKUT  ISOTRPS1 (Homo sapiens)8554872ClinVar Annotator: match by term: Congenital anomalies of kidney and urinary tractClinVarPMID:11112658 more ...
Trps1RatCraniosynostosis Syndrome, Autosomal Recessive  ISOTRPS1 (Homo sapiens)8554872ClinVar Annotator: match by term: Craniosynostosis syndromeClinVar 
Trps1Ratgenetic disease  ISOTRPS1 (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:10615131 more ...
Trps1Rathereditary multiple exostoses  ISOTRPS1 (Homo sapiens)8554872ClinVar Annotator: match by term: Multiple congenital exostosisClinVarPMID:28492532
Trps1RatMetaphyseal Chondrodysplasia  ISOTRPS1 (Homo sapiens)8554872ClinVar Annotator: match by term: Metaphyseal chondrodysplasiaClinVarPMID:25741868 more ...
Trps1Ratmicrocephaly  ISOTRPS1 (Homo sapiens)8554872ClinVar Annotator: match by term: MicrocephalyClinVarPMID:25741868
Trps1RatTrichorhinophalangeal Syndrome  ISOTRPS1 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:25333908 more ...
Trps1Rattrichorhinophalangeal syndrome type I  ISOTRPS1 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:10615131 more ...
Trps1Rattrichorhinophalangeal syndrome type II  ISOTRPS1 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:11112658 more ...
Trps1Rattrichorhinophalangeal syndrome type III  ISOTRPS1 (Homo sapiens)8554872ClinVar Annotator: match by term: Trichorhinophalangeal syndrome and type IIIClinVarPMID:10615131 more ...
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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Trps1RatAnimal Mammary Neoplasms  ISOTRPS1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:16316942
Trps1Ratbone development disease  ISOTRPS1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:19759027
Trps1Ratcarcinoma  ISOTRPS1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:16316942
Trps1RatCraniofacial Abnormalities  ISOTRPS1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:11708946 and PMID:19759027
Trps1RatExperimental Mammary Neoplasms  ISOTRPS1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:16316942
Trps1Rattrichorhinophalangeal syndrome type I  ISOTRPS1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTD 
Trps1Rattrichorhinophalangeal syndrome type II  ISOTRPS1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:11708946
Trps1Rattrichorhinophalangeal syndrome type III  ISOTRPS1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTD 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Trps1Rattrichorhinophalangeal syndrome type I  ISSTrps1 (Mus musculus)13592920OMIM:190350MouseDO 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Trps1Rattrichorhinophalangeal syndrome type I  ISOTRPS1 (Homo sapiens)7240710 OMIM 
Trps1Rattrichorhinophalangeal syndrome type III  ISOTRPS1 (Homo sapiens)7240710 OMIM 

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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Trps1Rat1,2-dichloroethane increases expressionISOTrps1 (Mus musculus)6480464ethylene dichloride results in increased expression of TRPS1 mRNACTDPMID:28960355
Trps1Rat17beta-hydroxy-17-methylestra-4,9,11-trien-3-one decreases expressionISOTRPS1 (Homo sapiens)6480464Metribolone results in decreased expression of TRPS1 mRNACTDPMID:19759027
Trps1Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOTrps1 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of TRPS1 mRNACTDPMID:21570461 and PMID:24058054
Trps1Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISOTrps1 (Mus musculus)6480464Tetrachlorodibenzodioxin results in increased expression of TRPS1 mRNACTDPMID:21354282 and PMID:37172768
Trps1Rat2,3,7,8-Tetrachlorodibenzofuran decreases expressionEXP 64804642 more ...CTDPMID:32109520
Trps1Rat3,4-methylenedioxymethamphetamine decreases expressionEXP 6480464N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of TRPS1 mRNACTDPMID:30071829
Trps1Rat4-hydroxyphenyl retinamide decreases expressionISOTrps1 (Mus musculus)6480464Fenretinide results in decreased expression of TRPS1 mRNACTDPMID:28973697
Trps1Ratacetamide increases expressionEXP 6480464acetamide results in increased expression of TRPS1 mRNACTDPMID:31881176
Trps1Rataflatoxin B1 decreases methylationISOTRPS1 (Homo sapiens)6480464Aflatoxin B1 results in decreased methylation of TRPS1 geneCTDPMID:27153756
Trps1Ratall-trans-retinoic acid increases expressionISOTRPS1 (Homo sapiens)6480464Tretinoin results in increased expression of TRPS1 mRNACTDPMID:21934132
Trps1Ratall-trans-retinoic acid increases expressionEXP 6480464Tretinoin results in increased expression of TRPS1 mRNACTDPMID:20488242
Trps1Ratalpha-Zearalanol multiple interactionsEXP 6480464[Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of TRPS1 mRNACTDPMID:35163327
Trps1Ratamphotericin B decreases expressionISOTRPS1 (Homo sapiens)6480464Amphotericin B analog results in decreased expression of TRPS1 mRNACTDPMID:28534445
Trps1Rataristolochic acid A decreases expressionISOTRPS1 (Homo sapiens)6480464aristolochic acid I results in decreased expression of TRPS1 mRNACTDPMID:33212167
Trps1RatAroclor 1254 decreases expressionISOTrps1 (Mus musculus)6480464Chlorodiphenyl (54% Chlorine) results in decreased expression of TRPS1 mRNACTDPMID:23650126
Trps1Ratarsenite(3-) multiple interactionsISOTRPS1 (Homo sapiens)6480464arsenite inhibits the reaction [G3BP1 protein binds to TRPS1 mRNA]CTDPMID:32406909
Trps1Ratbenzo[a]pyrene decreases expressionISOTRPS1 (Homo sapiens)6480464Benzo(a)pyrene results in decreased expression of TRPS1 mRNACTDPMID:20064835
Trps1Ratbenzo[a]pyrene increases methylationISOTRPS1 (Homo sapiens)6480464Benzo(a)pyrene results in increased methylation of TRPS1 3' UTRCTDPMID:27901495
Trps1Ratbenzo[a]pyrene affects methylationISOTRPS1 (Homo sapiens)6480464Benzo(a)pyrene affects the methylation of TRPS1 5' UTRCTDPMID:27901495
Trps1Ratbenzo[a]pyrene increases expressionISOTRPS1 (Homo sapiens)6480464Benzo(a)pyrene results in increased expression of TRPS1 mRNACTDPMID:22316170

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Biological Process
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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Trps1Ratbiological_process  ND 15984072/2007: no relevant rat dataRGD 
Trps1Ratcell surface receptor protein serine/threonine kinase signaling pathway acts_upstream_of_or_withinISOTrps1 (Mus musculus)1624291MGI:107191 more ...RGDPMID:18363966
Trps1Ratchondrocyte differentiation acts_upstream_of_or_withinISOTrps1 (Mus musculus)1624291MGI:107191 more ...RGDPMID:18363966
Trps1Rathair follicle development involved_inISOTrps1 (Mus musculus)1624291 PMID:23133399RGDPMID:23133399
Trps1Ratnegative regulation of DNA-templated transcription involved_inISOTrps1 (Mus musculus)1624291 PMID:23133399RGDPMID:23133399
Trps1Ratnegative regulation of DNA-templated transcription acts_upstream_of_or_withinISOTrps1 (Mus musculus)1624291PR:P56546 PMID:12444977RGDPMID:12444977
Trps1Ratnegative regulation of transcription by RNA polymerase II involved_inISOTRPS1 (Homo sapiens)1624291 PMID:12885770 more ...RGDPMID:12885770 more ...
Trps1Ratpositive regulation of extrinsic apoptotic signaling pathway via death domain receptors acts_upstream_of_or_withinISOTrps1 (Mus musculus)1624291MGI:107191 more ...RGDPMID:18363966
Trps1Ratregulation of chondrocyte differentiation involved_inISOTrps1 (Mus musculus)1624291 PMID:19389374RGDPMID:19389374
Trps1Ratregulation of DNA-templated transcription involved_inIEAInterPro:IPR000679 and InterPro:IPR0130881600115GO_REF:0000002InterProGO_REF:0000002
Trps1Ratregulation of gene expression involved_inIEAARBA:ARBA000283341600115GO_REF:0000117UniProtGO_REF:0000117
Trps1Ratregulation of transcription by RNA polymerase II involved_inIBAPANTHER:PTN002931555 and UniProtKB:Q9UHF71600115GO_REF:0000033GO_CentralGO_REF:0000033
Trps1Ratskeletal system development involved_inISOTRPS1 (Homo sapiens)1624291 PMID:10615131RGDPMID:10615131
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Cellular Component

  

Molecular Function
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#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Mutations in a new gene, encoding a zinc-finger protein, cause tricho-rhino-phalangeal syndrome type I. Momeni P, etal., Nat Genet. 2000 Jan;24(1):71-4.
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Comprehensive gene review and curation RGD comprehensive gene curation
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PMID:12444977   PMID:12885770   PMID:14680804   PMID:15491138   PMID:18363966   PMID:19389374   PMID:21673316   PMID:23133399  



Trps1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8783,806,121 - 84,032,609 (-)NCBIGRCr8
mRatBN7.2781,916,668 - 82,142,733 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl781,921,601 - 82,141,905 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx783,803,208 - 84,022,882 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0786,005,758 - 86,225,442 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0785,848,280 - 86,067,966 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0790,085,895 - 90,320,430 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl790,090,828 - 90,318,221 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0790,113,508 - 90,343,325 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4786,855,378 - 87,076,668 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1786,876,430 - 87,097,949 (-)NCBI
Celera778,810,727 - 79,029,498 (-)NCBICelera
Cytogenetic Map7q31NCBI
TRPS1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388115,408,496 - 115,668,975 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl8115,408,496 - 115,809,673 (-)EnsemblGRCh38hg38GRCh38
GRCh378116,420,724 - 116,681,202 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368116,489,900 - 116,750,402 (-)NCBINCBI36Build 36hg18NCBI36
Build 348116,489,899 - 116,750,429NCBI
Celera8112,607,772 - 112,867,949 (-)NCBICelera
Cytogenetic Map8q23.3NCBI
HuRef8111,746,115 - 111,962,229 (-)NCBIHuRef
CHM1_18116,461,345 - 116,721,859 (-)NCBICHM1_1
T2T-CHM13v2.08116,535,995 - 116,796,128 (-)NCBIT2T-CHM13v2.0
Trps1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391550,518,149 - 50,754,027 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1550,518,148 - 50,753,859 (-)EnsemblGRCm39 Ensembl
GRCm381550,654,757 - 50,890,631 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1550,654,752 - 50,890,463 (-)EnsemblGRCm38mm10GRCm38
MGSCv371550,486,303 - 50,721,587 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361550,490,516 - 50,720,115 (-)NCBIMGSCv36mm8
Celera1552,221,354 - 52,433,937 (-)NCBICelera
Cytogenetic Map15CNCBI
cM Map1519.18NCBI
Trps1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541721,680,116 - 21,913,173 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541721,674,545 - 21,913,137 (-)NCBIChiLan1.0ChiLan1.0
TRPS1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27132,802,726 - 133,069,136 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan18108,326,565 - 108,588,056 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v08112,079,147 - 112,339,567 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.18114,626,357 - 114,854,222 (-)NCBIpanpan1.1PanPan1.1panPan2
TRPS1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11315,017,180 - 15,273,177 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1315,022,652 - 15,273,666 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1315,005,955 - 15,263,461 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01315,305,244 - 15,563,018 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1315,308,610 - 15,562,778 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11315,053,664 - 15,309,547 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01315,150,277 - 15,407,958 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01315,394,399 - 15,652,945 (-)NCBIUU_Cfam_GSD_1.0
Trps1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530323,004,744 - 23,244,503 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647030,432,625 - 30,665,091 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647030,475,779 - 30,666,546 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRPS1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl422,905,637 - 23,159,546 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1422,905,627 - 23,162,862 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
TRPS1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18110,048,277 - 110,306,342 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl8110,050,705 - 110,260,394 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603930,041,925 - 30,303,926 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Trps1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476313,798,113 - 14,035,138 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476313,792,649 - 14,035,120 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Trps1
1393 total Variants

Predicted Target Of
Summary Value
Count of predictions:158
Count of miRNA genes:131
Interacting mature miRNAs:133
Transcripts:ENSRNOT00000050774
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


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The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
2293667Bss42Bone structure and strength QTL 427.250.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)74765143992651439Rat
10053722Scort27Serum corticosterone level QTL 272.410.0083blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)74322875088228750Rat
1331728Bp214Blood pressure QTL 2142.825arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)780221299124373579Rat
2317035Aia16Adjuvant induced arthritis QTL 162.71joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)759238038104238038Rat
1300127Srn1Serum renin concentration QTL 13.87blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)72940968384928080Rat
2293678Bss24Bone structure and strength QTL 246.710.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)74765143992651439Rat
1358361Sradr5Stress Responsive Adrenal Weight QTL 55.55adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)743747012108555253Rat
1357338Stl17Serum triglyceride level QTL 173.23blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)769736356112729554Rat
631513Scl7Serum cholesterol level QTL 74.1blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)73796056982960569Rat

1 to 10 of 42 rows
AI447310  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2781,919,710 - 81,919,825 (+)MAPPERmRatBN7.2
Rnor_6.0790,088,938 - 90,089,052NCBIRnor6.0
Rnor_5.0790,116,994 - 90,117,108UniSTSRnor5.0
RGSC_v3.4786,853,488 - 86,853,602UniSTSRGSC3.4
Celera778,808,837 - 78,808,951UniSTS
Cytogenetic Map7q31UniSTS
AU046994  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2782,131,965 - 82,132,073 (+)MAPPERmRatBN7.2
Rnor_6.0790,308,833 - 90,308,940NCBIRnor6.0
Rnor_5.0790,333,937 - 90,334,044UniSTSRnor5.0
RGSC_v3.4787,067,280 - 87,067,387UniSTSRGSC3.4
Celera779,020,126 - 79,020,217UniSTS
Cytogenetic Map7q31UniSTS
BM384689  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2781,921,484 - 81,921,643 (+)MAPPERmRatBN7.2
Rnor_6.0790,090,712 - 90,090,870NCBIRnor6.0
Rnor_5.0790,118,768 - 90,118,926UniSTSRnor5.0
RGSC_v3.4786,855,262 - 86,855,420UniSTSRGSC3.4
Celera778,810,611 - 78,810,769UniSTS
RH 3.4 Map7537.4UniSTS
Cytogenetic Map7q31UniSTS
Trps1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2782,099,874 - 82,100,574 (+)MAPPERmRatBN7.2
Rnor_6.0790,276,663 - 90,277,362NCBIRnor6.0
Rnor_5.0790,301,767 - 90,302,466UniSTSRnor5.0
Celera778,988,051 - 78,988,750UniSTS
Cytogenetic Map7q31UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31


1 to 16 of 16 rows
RefSeq Transcripts NM_001134837 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594744 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594745 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594746 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594747 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594748 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078760 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078761 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078762 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078764 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078765 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078767 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078768 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263244 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH473950 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 16 of 16 rows

Ensembl Acc Id: ENSRNOT00000050774   ⟹   ENSRNOP00000039913
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl781,921,601 - 82,141,354 (-)Ensembl
Rnor_6.0 Ensembl790,090,828 - 90,318,221 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000094294   ⟹   ENSRNOP00000077022
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl781,921,601 - 82,141,551 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000097264   ⟹   ENSRNOP00000088310
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl781,921,601 - 82,141,905 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000106247   ⟹   ENSRNOP00000083606
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl781,921,601 - 82,141,551 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000110775   ⟹   ENSRNOP00000096700
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl781,921,601 - 82,100,639 (-)Ensembl
RefSeq Acc Id: NM_001134837   ⟹   NP_001128309
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8783,811,497 - 84,031,235 (-)NCBI
mRatBN7.2781,921,601 - 82,141,354 (-)NCBI
Rnor_6.0790,090,828 - 90,318,221 (-)NCBI
Rnor_5.0790,113,508 - 90,343,325 (-)NCBI
RGSC_v3.4786,855,378 - 87,076,668 (-)RGD
Celera778,810,727 - 79,029,498 (-)RGD
Sequence:
RefSeq Acc Id: XM_039078760   ⟹   XP_038934688
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8783,806,121 - 84,031,020 (-)NCBI
mRatBN7.2781,916,668 - 82,141,137 (-)NCBI
RefSeq Acc Id: XM_039078761   ⟹   XP_038934689
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8783,806,121 - 84,031,019 (-)NCBI
mRatBN7.2781,916,668 - 82,141,137 (-)NCBI
RefSeq Acc Id: XM_039078762   ⟹   XP_038934690
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8783,806,121 - 84,031,677 (-)NCBI
mRatBN7.2781,916,668 - 82,141,686 (-)NCBI
RefSeq Acc Id: XM_039078764   ⟹   XP_038934692
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8783,806,121 - 84,001,792 (-)NCBI
mRatBN7.2781,916,668 - 82,105,530 (-)NCBI
RefSeq Acc Id: XM_039078765   ⟹   XP_038934693
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8783,806,121 - 84,032,609 (-)NCBI
mRatBN7.2781,916,668 - 82,142,733 (-)NCBI
RefSeq Acc Id: XM_039078767   ⟹   XP_038934695
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8783,806,121 - 84,030,447 (-)NCBI
mRatBN7.2781,916,668 - 82,140,568 (-)NCBI
RefSeq Acc Id: XM_039078768   ⟹   XP_038934696
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8783,806,121 - 84,031,020 (-)NCBI
mRatBN7.2781,916,668 - 82,141,138 (-)NCBI
RefSeq Acc Id: XM_063263244   ⟹   XP_063119314
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8783,806,121 - 84,031,675 (-)NCBI
1 to 5 of 14 rows
1 to 5 of 14 rows
RefSeq Acc Id: NP_001128309   ⟸   NM_001134837
- UniProtKB: A6HRD1 (UniProtKB/TrEMBL),   A0A8I5Y133 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000039913   ⟸   ENSRNOT00000050774
RefSeq Acc Id: XP_038934693   ⟸   XM_039078765
- Peptide Label: isoform X4
- UniProtKB: D3ZEM6 (UniProtKB/TrEMBL),   A0A8I5Y133 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038934690   ⟸   XM_039078762
- Peptide Label: isoform X3
- UniProtKB: A0A8I5Y133 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038934696   ⟸   XM_039078768
- Peptide Label: isoform X6
- UniProtKB: A0A8I5Y133 (UniProtKB/TrEMBL)
C2H2-type   GATA-type

Name Modeler Protein Id AA Range Protein Structure
AF-D3ZEM6-F1-model_v2 AlphaFold D3ZEM6 1-1281 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13695321
Promoter ID:EPDNEW_R5846
Type:multiple initiation site
Name:Trps1_1
Description:transcriptional repressor GATA binding 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0790,318,190 - 90,318,250EPDNEW


1 to 40 of 42 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-33445 BioCyc
Ensembl Genes ENSRNOG00000024998 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000050774 ENTREZGENE
  ENSRNOT00000050774.3 UniProtKB/TrEMBL
  ENSRNOT00000094294 ENTREZGENE
  ENSRNOT00000094294.1 UniProtKB/TrEMBL
  ENSRNOT00000097264.1 UniProtKB/TrEMBL
  ENSRNOT00000106247 ENTREZGENE
  ENSRNOT00000106247.1 UniProtKB/TrEMBL
  ENSRNOT00000110775 ENTREZGENE
  ENSRNOT00000110775.1 UniProtKB/TrEMBL
  ENSRNOT00000146817 ENTREZGENE
  ENSRNOT00000157182 ENTREZGENE
Gene3D-CATH 3.30.50.10 UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/TrEMBL
InterPro Trps1 UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/TrEMBL
  Znf_GATA UniProtKB/TrEMBL
  Znf_NHR/GATA UniProtKB/TrEMBL
KEGG Report rno:299897 UniProtKB/TrEMBL
NCBI Gene 299897 ENTREZGENE
PANTHER PTHR47034 UniProtKB/TrEMBL
  ZINC FINGER TRANSCRIPTION FACTOR TRPS1 UniProtKB/TrEMBL
Pfam GATA UniProtKB/TrEMBL
PhenoGen Trps1 PhenoGen
PRINTS GATAZNFINGER UniProtKB/TrEMBL
PROSITE GATA_ZN_FINGER_1 UniProtKB/TrEMBL
  GATA_ZN_FINGER_2 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000024998 RatGTEx
SMART ZnF_C2H2 UniProtKB/TrEMBL
  ZnF_GATA UniProtKB/TrEMBL
Superfamily-SCOP Glucocorticoid receptor-like (DNA-binding domain) UniProtKB/TrEMBL
  SSF57667 UniProtKB/TrEMBL
UniProt A0A8I5Y133 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZWX6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A7M4_RAT UniProtKB/TrEMBL
  A0A8I6B4M4_RAT UniProtKB/TrEMBL
1 to 40 of 42 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-19 Trps1  transcriptional repressor GATA binding 1  Trps1  trichorhinophalangeal syndrome I  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-09-29 Trps1  trichorhinophalangeal syndrome I  Trps1  trichorhinophalangeal syndrome I homolog (human)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-12-15 Trps1  trichorhinophalangeal syndrome I homolog (human)  Trps1  trichorhinophalangeal syndrome I (human)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-04 Trps1  trichorhinophalangeal syndrome I (human)  Trps1_predicted  trichorhinophalangeal syndrome I (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-12 Trps1_predicted  trichorhinophalangeal syndrome I (predicted)      Symbol and Name status set to approved 70820 APPROVED