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Gene: Slc30a8 (solute carrier family 30 member 8) Rattus norvegicus

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Symbol:

Slc30a8

Name:

solute carrier family 30 member 8

RGD ID:

1308282

Description:

Enables zinc ion transmembrane transporter activity. Involved in several processes, including intracellular zinc ion homeostasis; positive regulation of insulin secretion; and zinc ion import across plasma membrane. Predicted to be located in secretory granule membrane. Predicted to be active in plasma membrane and secretory granule. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human SLC30A8 (solute carrier family 30 member 8); INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; aldehydo-D-glucose; bisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC299903; proton-coupled zinc antiporter SLC30A8; solute carrier family 30 (zinc transporter), member 8; zinc transporter 8; ZnT-8

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Allele / Splice:

Slc30a8^em1Mcwi Slc30a8^em2Mcwi

Genetic Models:

SS-Slc30a8^em1Mcwi SS-Slc30a8^em2Mcwi

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	85,481,864 - 85,517,255 (+)	NCBI		GRCr8
mRatBN7.2	7	83,591,993 - 83,627,786 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	83,591,993 - 83,626,305 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	7	85,509,786 - 85,542,609 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	87,710,991 - 87,743,815 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	87,515,694 - 87,548,480 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	91,832,988 - 91,869,329 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	91,832,988 - 91,867,300 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	92,476,024 - 92,512,365 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	88,583,770 - 88,617,145 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	7	88,604,575 - 88,639,923 (+)	NCBI
Celera	7	80,455,350 - 80,488,134 (+)	NCBI		Celera
Cytogenetic Map	7	q31	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Slc30a8	Rat	hereditary multiple exostoses		ISO	SLC30A8 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Multiple congenital exostosis	ClinVar	PMID:28492532
Slc30a8	Rat	maturity-onset diabetes of the young type 1		ISO	SLC30A8 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Type 2 diabetes mellitus	ClinVar	PMID:24584071 more ...
Slc30a8	Rat	trichorhinophalangeal syndrome type I		ISO	SLC30A8 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Trichorhinophalangeal dysplasia type I	ClinVar	PMID:25741868
Slc30a8	Rat	trichorhinophalangeal syndrome type III		ISO	SLC30A8 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Trichorhinophalangeal syndrome and type III	ClinVar	PMID:11112658 more ...
Slc30a8	Rat	type 2 diabetes mellitus		ISO	SLC30A8 (Homo sapiens)	8554872	ClinVar more ...	ClinVar	PMID:17293876 more ...

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Slc30a8	Rat	type 2 diabetes mellitus		ISO	SLC30A8 (Homo sapiens)	11554173	CTD more ...	CTD	PMID:19479076 more ...

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Slc30a8	Rat	type 2 diabetes mellitus	susceptibility	ISO	SLC30A8 (Homo sapiens)	7240710		OMIM

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Slc30a8	Rat	2,3,7,8-Tetrachlorodibenzofuran	increases expression	EXP		6480464	2 more ...	CTD	PMID:32109520
Slc30a8	Rat	3-iodothyronamine	affects uptake	ISO	SLC30A8 (Homo sapiens)	6480464	SLC30A8 mRNA affects the uptake of 3-iodothyronamine	CTD	PMID:19074582
Slc30a8	Rat	4,4'-diaminodiphenylmethane	decreases expression	ISO	Slc30a8 (Mus musculus)	6480464	4 and 4'-diaminodiphenylmethane results in decreased expression of SLC30A8 mRNA	CTD	PMID:18648102
Slc30a8	Rat	acrylamide	decreases expression	ISO	Slc30a8 (Mus musculus)	6480464	Acrylamide results in decreased expression of SLC30A8 mRNA	CTD	PMID:30807115
Slc30a8	Rat	aflatoxin B1	decreases methylation	ISO	SLC30A8 (Homo sapiens)	6480464	Aflatoxin B1 results in decreased methylation of SLC30A8 gene	CTD	PMID:27153756
Slc30a8	Rat	aflatoxin B1	increases methylation	ISO	SLC30A8 (Homo sapiens)	6480464	Aflatoxin B1 results in increased methylation of SLC30A8 intron	CTD	PMID:30157460
Slc30a8	Rat	aldehydo-D-glucose	multiple interactions	ISO	SLC30A8 (Homo sapiens)	6480464	SLC30A8 protein promotes the reaction [Glucose results in increased secretion of INS protein]	CTD	PMID:16984975
Slc30a8	Rat	aldehydo-D-glucose	multiple interactions	EXP		6480464	[Glucose co-treated with dihydroxyethyldithiocarbamate] results in decreased expression of SLC30A8 more ...	CTD	PMID:19479076 more ...
Slc30a8	Rat	aldehydo-D-glucose	decreases expression	EXP		6480464	Glucose results in decreased expression of SLC30A8 and Glucose results in decreased expression of SLC30A8 mRNA	CTD	PMID:19492079 and PMID:23056475
Slc30a8	Rat	aldehydo-D-glucose	multiple interactions	ISO	Slc30a8 (Mus musculus)	6480464	SLC30A8 gene mutant form inhibits the reaction [Glucose results in increased secretion of INS1 protein]	CTD	PMID:19450229
Slc30a8	Rat	benzo[a]pyrene	decreases expression	ISO	SLC30A8 (Homo sapiens)	6480464	Benzo(a)pyrene results in decreased expression of SLC30A8 mRNA	CTD	PMID:22316170
Slc30a8	Rat	benzo[a]pyrene	affects methylation	ISO	SLC30A8 (Homo sapiens)	6480464	Benzo(a)pyrene affects the methylation of SLC30A8 promoter	CTD	PMID:27901495
Slc30a8	Rat	benzo[a]pyrene	decreases methylation	ISO	SLC30A8 (Homo sapiens)	6480464	Benzo(a)pyrene results in decreased methylation of SLC30A8 3' UTR	CTD	PMID:27901495
Slc30a8	Rat	bisphenol A	affects expression	EXP		6480464	bisphenol A affects the expression of SLC30A8 mRNA	CTD	PMID:25181051
Slc30a8	Rat	bisphenol A	decreases expression	ISO	SLC30A8 (Homo sapiens)	6480464	bisphenol A results in decreased expression of SLC30A8 mRNA	CTD	PMID:31715268
Slc30a8	Rat	bisphenol A	decreases expression	EXP		6480464	bisphenol A results in decreased expression of SLC30A8 mRNA	CTD	PMID:30816183 and PMID:32528016
Slc30a8	Rat	cadmium atom	affects expression	ISO	Slc30a8 (Mus musculus)	6480464	Cadmium affects the expression of SLC30A8 mRNA	CTD	PMID:25294218
Slc30a8	Rat	cadmium atom	multiple interactions	ISO	SLC30A8 (Homo sapiens)	6480464	[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SLC30A8 mRNA	CTD	PMID:35301059
Slc30a8	Rat	cadmium dichloride	multiple interactions	ISO	SLC30A8 (Homo sapiens)	6480464	[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SLC30A8 mRNA	CTD	PMID:35301059
Slc30a8	Rat	CGP 52608	multiple interactions	ISO	SLC30A8 (Homo sapiens)	6480464	CGP 52608 promotes the reaction [RORA protein binds to SLC30A8 gene]	CTD	PMID:28238834
Slc30a8	Rat	D-glucose	multiple interactions	EXP		6480464	[Glucose co-treated with dihydroxyethyldithiocarbamate] results in decreased expression of SLC30A8 more ...	CTD	PMID:19479076 more ...
Slc30a8	Rat	D-glucose	decreases expression	EXP		6480464	Glucose results in decreased expression of SLC30A8 and Glucose results in decreased expression of SLC30A8 mRNA	CTD	PMID:19492079 and PMID:23056475
Slc30a8	Rat	D-glucose	multiple interactions	ISO	SLC30A8 (Homo sapiens)	6480464	SLC30A8 protein promotes the reaction [Glucose results in increased secretion of INS protein]	CTD	PMID:16984975
Slc30a8	Rat	D-glucose	multiple interactions	ISO	Slc30a8 (Mus musculus)	6480464	SLC30A8 gene mutant form inhibits the reaction [Glucose results in increased secretion of INS1 protein]	CTD	PMID:19450229
Slc30a8	Rat	dichloroacetic acid	increases expression	ISO	Slc30a8 (Mus musculus)	6480464	Dichloroacetic Acid results in increased expression of SLC30A8 mRNA	CTD	PMID:28962523
Slc30a8	Rat	diquat	increases expression	ISO	Slc30a8 (Mus musculus)	6480464	Diquat results in increased expression of SLC30A8 mRNA	CTD	PMID:36851058
Slc30a8	Rat	entinostat	increases expression	ISO	SLC30A8 (Homo sapiens)	6480464	entinostat results in increased expression of SLC30A8 mRNA	CTD	PMID:27188386
Slc30a8	Rat	epoxiconazole	decreases expression	ISO	Slc30a8 (Mus musculus)	6480464	epoxiconazole results in decreased expression of SLC30A8 mRNA	CTD	PMID:35436446
Slc30a8	Rat	fulvestrant	increases methylation	ISO	SLC30A8 (Homo sapiens)	6480464	Fulvestrant results in increased methylation of SLC30A8 gene	CTD	PMID:31601247
Slc30a8	Rat	glucose	multiple interactions	EXP		6480464	[Glucose co-treated with dihydroxyethyldithiocarbamate] results in decreased expression of SLC30A8 more ...	CTD	PMID:19479076 more ...
Slc30a8	Rat	glucose	decreases expression	EXP		6480464	Glucose results in decreased expression of SLC30A8 and Glucose results in decreased expression of SLC30A8 mRNA	CTD	PMID:19492079 and PMID:23056475
Slc30a8	Rat	glucose	multiple interactions	ISO	SLC30A8 (Homo sapiens)	6480464	SLC30A8 protein promotes the reaction [Glucose results in increased secretion of INS protein]	CTD	PMID:16984975
Slc30a8	Rat	glucose	multiple interactions	ISO	Slc30a8 (Mus musculus)	6480464	SLC30A8 gene mutant form inhibits the reaction [Glucose results in increased secretion of INS1 protein]	CTD	PMID:19450229
Slc30a8	Rat	glyphosate	increases expression	EXP		6480464	Glyphosate results in increased expression of SLC30A8 mRNA	CTD	PMID:38314887
Slc30a8	Rat	N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine	multiple interactions	EXP		6480464	N more ...	CTD	PMID:23056475
Slc30a8	Rat	paracetamol	affects expression	ISO	Slc30a8 (Mus musculus)	6480464	Acetaminophen affects the expression of SLC30A8 mRNA	CTD	PMID:17562736
Slc30a8	Rat	potassium chloride	multiple interactions	EXP		6480464	SLC30A8 protein affects the reaction [Potassium Chloride results in increased secretion of INS1 protein]	CTD	PMID:19479076
Slc30a8	Rat	sodium arsenite	increases expression	ISO	Slc30a8 (Mus musculus)	6480464	sodium arsenite results in increased expression of SLC30A8 mRNA	CTD	PMID:37682722
Slc30a8	Rat	trichloroethene	decreases methylation	EXP		6480464	Trichloroethylene results in decreased methylation of SLC30A8 gene	CTD	PMID:27618143
Slc30a8	Rat	trichloroethene	decreases expression	EXP		6480464	Trichloroethylene results in decreased expression of SLC30A8 mRNA	CTD	PMID:33387578
Slc30a8	Rat	triclosan	decreases expression	ISO	SLC30A8 (Homo sapiens)	6480464	Triclosan results in decreased expression of SLC30A8 mRNA	CTD	PMID:30510588
Slc30a8	Rat	valproic acid	decreases methylation	ISO	SLC30A8 (Homo sapiens)	6480464	Valproic Acid results in decreased methylation of SLC30A8 gene	CTD	PMID:29154799
Slc30a8	Rat	valproic acid	affects expression	ISO	SLC30A8 (Homo sapiens)	6480464	Valproic Acid affects the expression of SLC30A8 mRNA	CTD	PMID:25979313
Slc30a8	Rat	zinc atom	increases abundance	ISO	SLC30A8 (Homo sapiens)	6480464	SLC30A8 protein results in increased abundance of Zinc	CTD	PMID:16984975
Slc30a8	Rat	zinc atom	affects uptake	EXP		6480464	SLC30A8 protein affects the uptake of Zinc	CTD	PMID:19479076
Slc30a8	Rat	zinc atom	affects localization	ISO	SLC30A8 (Homo sapiens)	6480464	SLC30A8 protein affects the localization of Zinc	CTD	PMID:15331542
Slc30a8	Rat	zinc atom	increases uptake	ISO	SLC30A8 (Homo sapiens)	6480464	SLC30A8 protein results in increased uptake of Zinc	CTD	PMID:16984975
Slc30a8	Rat	zinc atom	increases transport	ISO	SLC30A8 (Homo sapiens)	6480464	SLC30A8 protein results in increased transport of Zinc	CTD	PMID:18326752
Slc30a8	Rat	zinc(0)	increases abundance	ISO	SLC30A8 (Homo sapiens)	6480464	SLC30A8 protein results in increased abundance of Zinc	CTD	PMID:16984975
Slc30a8	Rat	zinc(0)	increases transport	ISO	SLC30A8 (Homo sapiens)	6480464	SLC30A8 protein results in increased transport of Zinc	CTD	PMID:18326752
Slc30a8	Rat	zinc(0)	increases uptake	ISO	SLC30A8 (Homo sapiens)	6480464	SLC30A8 protein results in increased uptake of Zinc	CTD	PMID:16984975
Slc30a8	Rat	zinc(0)	affects localization	ISO	SLC30A8 (Homo sapiens)	6480464	SLC30A8 protein affects the localization of Zinc	CTD	PMID:15331542
Slc30a8	Rat	zinc(0)	affects uptake	EXP		6480464	SLC30A8 protein affects the uptake of Zinc	CTD	PMID:19479076

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Slc30a8	Rat	glucose homeostasis	NOT\|involved_in	ISO	Slc30a8 (Mus musculus)	1624291	PMID:19450229	RGD	PMID:19450229
Slc30a8	Rat	insulin processing	involved_in	ISO	Slc30a8 (Mus musculus)	1624291	MGI:4362061 PMID:19542200 and PMID:19706465	RGD	PMID:19542200 and PMID:19706465
Slc30a8	Rat	insulin processing	involved_in	IEA	UniProtKB:Q8BGG0 and ensembl:ENSMUSP00000035257	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Slc30a8	Rat	insulin secretion		IMP		2315022		RGD
Slc30a8	Rat	insulin secretion	involved_in	IEA	UniProtKB:Q8BGG0 and ensembl:ENSMUSP00000035257	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Slc30a8	Rat	insulin secretion	involved_in	IEA	UniProtKB:Q8IWU4 and ensembl:ENSP00000415011	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Slc30a8	Rat	insulin secretion	involved_in	IBA	MGI:2442682 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Slc30a8	Rat	insulin secretion	involved_in	ISO	Slc30a8 (Mus musculus)	1624291	PMID:19450229	RGD	PMID:19450229
Slc30a8	Rat	insulin secretion	involved_in	ISO	SLC30A8 (Homo sapiens)	1624291	PMID:16984975	RGD	PMID:16984975
Slc30a8	Rat	intracellular zinc ion homeostasis	involved_in	ISO	Slc30a8 (Mus musculus)	1624291	PMID:19450229	RGD	PMID:19450229
Slc30a8	Rat	intracellular zinc ion homeostasis	involved_in	IEA	UniProtKB:Q8BGG0 and ensembl:ENSMUSP00000035257	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Slc30a8	Rat	intracellular zinc ion homeostasis	involved_in	IMP		2315022	PMID:19479076	BHF-UCL
Slc30a8	Rat	monoatomic cation transport	involved_in	IEA	InterPro:IPR002524	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Slc30a8	Rat	monoatomic ion transport	involved_in	IEA	UniProtKB-KW:KW-0406	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Slc30a8	Rat	positive regulation of insulin secretion	involved_in	IMP		2315022	PMID:19479076	BHF-UCL
Slc30a8	Rat	regulation of vesicle-mediated transport	involved_in	IMP		2315022	PMID:19479076	BHF-UCL
Slc30a8	Rat	response to glucose	involved_in	IMP		2315022	PMID:19479076	BHF-UCL
Slc30a8	Rat	response to glucose	involved_in	IEA	UniProtKB:Q8IWU4 and ensembl:ENSP00000415011	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Slc30a8	Rat	response to glucose	involved_in	IBA	MGI:2442682 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Slc30a8	Rat	response to glucose	involved_in	IEA	UniProtKB:Q8BGG0 and ensembl:ENSMUSP00000035257	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Slc30a8	Rat	response to glucose	involved_in	ISO	SLC30A8 (Homo sapiens)	1624291	PMID:16984975	RGD	PMID:16984975
Slc30a8	Rat	response to glucose	involved_in	ISO	Slc30a8 (Mus musculus)	1624291	PMID:19450229	RGD	PMID:19450229
Slc30a8	Rat	response to interleukin-1		IEP		2315023		RGD
Slc30a8	Rat	response to type II interferon		IEP		2315023		RGD
Slc30a8	Rat	response to zinc ion	involved_in	IBA	FB:FBgn0025693 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Slc30a8	Rat	transmembrane transport	involved_in	IEA	InterPro:IPR002524	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Slc30a8	Rat	zinc ion import across plasma membrane	involved_in	IMP		2315022	PMID:19479076	BHF-UCL
Slc30a8	Rat	zinc ion import into organelle	involved_in	ISS	UniProtKB:Q8IWU4	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Slc30a8	Rat	zinc ion import into organelle	involved_in	IEA	UniProtKB:Q8IWU4 and ensembl:ENSP00000415011	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Slc30a8	Rat	zinc ion import into organelle	involved_in	ISO	SLC30A8 (Homo sapiens)	1624291	PMID:16984975	RGD	PMID:16984975
Slc30a8	Rat	zinc ion transmembrane transport	involved_in	IBA	FB:FBgn0028516 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Slc30a8	Rat	zinc ion transmembrane transport	involved_in	IEA	ARBA:ARBA00034597	1600115	GO_REF:0000117	UniProt	GO_REF:0000117
Slc30a8	Rat	zinc ion transport	involved_in	ISO	SLC30A8 (Homo sapiens)	1624291	PMID:15331542	RGD	PMID:15331542
Slc30a8	Rat	zinc ion transport	involved_in	IEA	UniProtKB-KW:KW-0864	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Slc30a8	Rat	zinc ion transport	involved_in	IEA	UniProtKB:Q8IWU4 and ensembl:ENSP00000415011	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Slc30a8	Rat	cytoplasmic vesicle	located_in	IEA	UniProtKB-KW:KW-0968	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Slc30a8	Rat	cytoplasmic vesicle	located_in	IEA	UniProtKB:Q8BGG0 and ensembl:ENSMUSP00000035257	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Slc30a8	Rat	cytoplasmic vesicle	located_in	ISO	Slc30a8 (Mus musculus)	1624291	PMID:19095428	RGD	PMID:19095428
Slc30a8	Rat	Golgi apparatus	NOT\|located_in	ISO	SLC30A8 (Homo sapiens)	1624291	PMID:15331542	RGD	PMID:15331542
Slc30a8	Rat	intracellular membrane-bounded organelle	located_in	ISO	SLC30A8 (Homo sapiens) more ...	1624291		RGD	GO_REF:0000052
Slc30a8	Rat	intracellular membrane-bounded organelle	located_in	IEA	UniProtKB:Q8IWU4 and ensembl:ENSP00000415011	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Slc30a8	Rat	membrane	located_in	IEA	UniProtKB-KW:KW-0472	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Slc30a8	Rat	membrane	located_in	IEA	InterPro:IPR002524	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Slc30a8	Rat	plasma membrane	located_in	ISO	SLC30A8 (Homo sapiens)	1624291	PMID:15331542	RGD	PMID:15331542
Slc30a8	Rat	plasma membrane	located_in	IEA	UniProtKB-SubCell:SL-0039	1600115	GO_REF:0000044	UniProt	GO_REF:0000044
Slc30a8	Rat	plasma membrane	located_in	IEA	UniProtKB:Q8IWU4 and ensembl:ENSP00000415011	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Slc30a8	Rat	plasma membrane	located_in	ISO	SLC30A8 (Homo sapiens) more ...	1624291		RGD	GO_REF:0000052
Slc30a8	Rat	plasma membrane	is_active_in	IBA	FB:FBgn0028516 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Slc30a8	Rat	plasma membrane	located_in	IEA	UniProtKB-KW:KW-1003	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Slc30a8	Rat	secretory granule	located_in	ISO	SLC30A8 (Homo sapiens)	1624291	PMID:15331542	RGD	PMID:15331542
Slc30a8	Rat	secretory granule	located_in	IEA	UniProtKB:Q8IWU4 and ensembl:ENSP00000415011	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Slc30a8	Rat	secretory granule	is_active_in	IEA	UniProtKB:Q8BGG0 and ensembl:ENSMUSP00000035257	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Slc30a8	Rat	secretory granule	is_active_in	ISO	Slc30a8 (Mus musculus)	1624291	PMID:20424817	RGD	PMID:20424817
Slc30a8	Rat	secretory granule membrane	located_in	ISO	SLC30A8 (Homo sapiens)	1624291	PMID:16984975	RGD	PMID:16984975
Slc30a8	Rat	secretory granule membrane	is_active_in	ISO	Slc30a8 (Mus musculus)	1624291	PMID:20424817	RGD	PMID:20424817
Slc30a8	Rat	secretory granule membrane	located_in	ISS	UniProtKB:Q8IWU4	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Slc30a8	Rat	secretory granule membrane	located_in	IEA	UniProtKB:Q8IWU4 and ensembl:ENSP00000415011	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Slc30a8	Rat	secretory granule membrane	is_active_in	IEA	UniProtKB:Q8BGG0 and ensembl:ENSMUSP00000035257	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Slc30a8	Rat	transport vesicle membrane	located_in	IEA	UniProtKB-SubCell:SL-0245	1600115	GO_REF:0000044	UniProt	GO_REF:0000044

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Slc30a8	Rat	antiporter activity	enables	IEA	UniProtKB-KW:KW-0050	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Slc30a8	Rat	metal ion binding	enables	IEA	UniProtKB-KW:KW-0479	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Slc30a8	Rat	monoatomic cation transmembrane transporter activity	enables	IEA	InterPro:IPR002524	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Slc30a8	Rat	protein binding	enables	ISO	SLC30A8 (Homo sapiens)	1624291	UniProtKB:A8MZ59 more ...	RGD	PMID:24955142 more ...
Slc30a8	Rat	protein homodimerization activity	enables	ISO	Slc30a8 (Mus musculus)	1624291	UniProtKB:Q8BGG0 and PMID:19095428	RGD	PMID:19095428
Slc30a8	Rat	protein homodimerization activity	enables	IEA	UniProtKB:Q8BGG0 and ensembl:ENSMUSP00000035257	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Slc30a8	Rat	zinc ion transmembrane transporter activity	enables	ISO	SLC30A8 (Homo sapiens)	1624291	PMID:15331542	RGD	PMID:15331542
Slc30a8	Rat	zinc ion transmembrane transporter activity	enables	IEA	UniProtKB:Q8IWU4 and ensembl:ENSP00000415011	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Slc30a8	Rat	zinc ion transmembrane transporter activity	enables	ISO	Slc30a8 (Mus musculus)	1624291	MGI:4362060 more ...	RGD	PMID:19542200 more ...
Slc30a8	Rat	zinc ion transmembrane transporter activity	enables	IBA	FB:FBgn0028516 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Slc30a8	Rat	zinc ion transmembrane transporter activity	enables	IEA	UniProtKB:Q8BGG0 and ensembl:ENSMUSP00000035257	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Slc30a8	Rat	zinc ion transmembrane transporter activity	enables	IMP		2315022	PMID:19479076	BHF-UCL
Slc30a8	Rat	zinc:proton antiporter activity	enables	ISO	SLC30A8 (Homo sapiens)	1624291	PMID:32723473	RGD	PMID:32723473
Slc30a8	Rat	zinc:proton antiporter activity	enables	ISS	UniProtKB:Q8IWU4	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Slc30a8	Rat	zinc:proton antiporter activity	enables	IEA	UniProtKB:Q8IWU4 and ensembl:ENSP00000415011	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107

#	Reference Title	Reference Citation
1.	Zinc transporter gene expression is regulated by pro-inflammatory cytokines: a potential role for zinc transporters in beta-cell apoptosis?	Egefjord L, etal., BMC Endocr Disord. 2009 Feb 25;9(1):7.
2.	Down-regulation of ZnT8 expression in INS-1 rat pancreatic beta cells reduces insulin content and glucose-inducible insulin secretion.	Fu Y, etal., PLoS One. 2009 May 25;4(5):e5679.
3.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
5.	Diabetes-linked zinc transporter ZnT8 is a homodimeric protein expressed by distinct rodent endocrine cell types in the pancreas and other glands.	Murgia C, etal., Nutr Metab Cardiovasc Dis. 2009 Jul;19(6):431-9. Epub 2008 Dec 17.
6.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
7.	GOA pipeline	RGD automated data pipeline
8.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
10.	Comprehensive gene review and curation	RGD comprehensive gene curation

PMID:15331542	PMID:16984975	PMID:19450229	PMID:19706465	PMID:21208276	PMID:23209723	PMID:26281917	PMID:26720469

Slc30a8
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	85,481,864 - 85,517,255 (+)	NCBI		GRCr8
mRatBN7.2	7	83,591,993 - 83,627,786 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	83,591,993 - 83,626,305 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	7	85,509,786 - 85,542,609 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	87,710,991 - 87,743,815 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	87,515,694 - 87,548,480 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	91,832,988 - 91,869,329 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	91,832,988 - 91,867,300 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	92,476,024 - 92,512,365 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	88,583,770 - 88,617,145 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	7	88,604,575 - 88,639,923 (+)	NCBI
Celera	7	80,455,350 - 80,488,134 (+)	NCBI		Celera
Cytogenetic Map	7	q31	NCBI

SLC30A8
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	116,950,217 - 117,176,714 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	8	116,950,273 - 117,176,714 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	8	117,962,456 - 118,188,953 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	118,216,518 - 118,258,134 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	8	118,216,747 - 118,254,101	NCBI
Celera	8	114,151,202 - 114,377,691 (+)	NCBI		Celera
Cytogenetic Map	8	q24.11	NCBI
HuRef	8	113,288,921 - 113,515,635 (+)	NCBI		HuRef
CHM1_1	8	118,002,722 - 118,228,963 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	8	118,078,388 - 118,305,142 (+)	NCBI		T2T-CHM13v2.0

Slc30a8
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	15	52,158,949 - 52,199,194 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	15	52,158,949 - 52,199,194 (+)	Ensembl		GRCm39 Ensembl
GRCm38	15	52,295,553 - 52,335,798 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	15	52,295,553 - 52,335,798 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	15	52,127,108 - 52,167,288 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	15	52,125,636 - 52,165,816 (+)	NCBI		MGSCv36	mm8
Celera	15	53,863,656 - 53,904,335 (+)	NCBI		Celera
Cytogenetic Map	15	C	NCBI
cM Map	15	19.88	NCBI

Slc30a8
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955417	23,207,146 - 23,236,874 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955417	23,207,146 - 23,239,170 (+)	NCBI	ChiLan1.0	ChiLan1.0

SLC30A8
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	134,356,700 - 134,583,629 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	8	109,872,083 - 110,098,929 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	113,624,785 - 113,851,633 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	8	116,167,700 - 116,394,095 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	116,223,595 - 116,394,095 (+)	Ensembl	panpan1.1		panPan2

SLC30A8
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	13	16,602,255 - 16,637,299 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	13	16,601,912 - 16,635,880 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	13	16,603,610 - 16,638,559 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	13	16,898,497 - 16,933,443 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	13	16,898,295 - 16,932,026 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	13	16,635,055 - 16,670,008 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	13	16,734,977 - 16,770,163 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	13	16,978,714 - 17,013,658 (+)	NCBI		UU_Cfam_GSD_1.0

Slc30a8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	21,687,819 - 21,725,947 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936470	29,114,713 - 29,151,993 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936470	29,114,713 - 29,151,993 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SLC30A8
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	21,517,486 - 21,555,746 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	21,517,009 - 21,557,747 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	22,786,105 - 22,824,455 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SLC30A8
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	111,588,517 - 111,819,908 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	8	111,769,181 - 111,815,885 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666039	28,509,132 - 28,557,839 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Slc30a8
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624763	15,431,806 - 15,461,833 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624763	15,393,221 - 15,469,819 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in Slc30a8
83 total Variants

Predicted Target Of

	Summary Value
Count of predictions:	112
Count of miRNA genes:	92
Interacting mature miRNAs:	96
Transcripts:	ENSRNOT00000006410
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1300179	Kidm5	Kidney mass QTL 5	3.51		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	7	43747012	135012528	Rat
2293667	Bss42	Bone structure and strength QTL 42	7.25	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra cross-sectional area (CMO:0001689)	7	47651439	92651439	Rat
10053722	Scort27	Serum corticosterone level QTL 27	2.41	0.0083	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	7	43228750	88228750	Rat
1331728	Bp214	Blood pressure QTL 214	2.825		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	80221299	124373579	Rat
2317035	Aia16	Adjuvant induced arthritis QTL 16	2.71		joint integrity trait (VT:0010548)	right rear ankle joint diameter (CMO:0002150)	7	59238038	104238038	Rat
1300127	Srn1	Serum renin concentration QTL 1	3.87		blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	7	29409683	84928080	Rat
2293678	Bss24	Bone structure and strength QTL 24	6.71	0.0001	femur morphology trait (VT:0000559)	femur cross-sectional area (CMO:0001661)	7	47651439	92651439	Rat
1358361	Sradr5	Stress Responsive Adrenal Weight QTL 5	5.55		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	7	43747012	108555253	Rat
1357338	Stl17	Serum triglyceride level QTL 17	3.23		blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	7	69736356	112729554	Rat
634331	Pia17	Pristane induced arthritis QTL 17	4.7		joint integrity trait (VT:0010548)	arthritic paw count (CMO:0001460)	7	73829340	130221005	Rat
1358914	Bp266	Blood pressure QTL 266			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	83591953	134666232	Rat
2293685	Bmd21	Bone mineral density QTL 21	4.2	0.0003	femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	7	47651439	92651439	Rat
631504	Cm27	Cardiac mass QTL 27	3.45		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	7	44421311	118198041	Rat
634322	Bw12	Body weight QTL 12	0		body mass (VT:0001259)	body weight (CMO:0000012)	7	83153392	128153392	Rat
70173	Niddm19	Non-insulin dependent diabetes mellitus QTL 19	4.33	0.00005	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	7	64002457	135012528	Rat
634326	Hc3	Hypercalciuria QTL 3	2.1		urine calcium amount (VT:0002985)	urine calcium excretion rate (CMO:0000763)	7	42787314	87787314	Rat
2317052	Aia17	Adjuvant induced arthritis QTL 17	2.13		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	7	81737938	126737938	Rat
631529	Tls2	T-lymphoma susceptibility QTL 2	0	0.001	thymus integrity trait (VT:0010555)	percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)	7	80221299	109401111	Rat
2293696	Bmd32	Bone mineral density QTL 32	5.1	0.0001	femur strength trait (VT:0010010)	femoral neck polar moment of inertia (CMO:0001670)	7	47651439	92651439	Rat
1300151	Bp181	Blood pressure QTL 181	3.36		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	7	53612714	103945643	Rat
1559283	Emca4	Estrogen-induced mammary cancer QTL 4	3.7		mammary gland integrity trait (VT:0010552)	percentage of study population developing mammary tumors during a period of time (CMO:0000948)	7	62004452	101773158	Rat
1643004	Pain2	Pain QTL 2	1		mechanical nociception trait (VT:0002734)	self mutilation severity score (CMO:0002145)	7	9462246	98011544	Rat
738030	Anxrr8	Anxiety related response QTL 8	4.1		exploratory behavior trait (VT:0010471)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	7	46590070	91590070	Rat
1300149	Cm6	Cardiac mass QTL 6	4.09		heart mass (VT:0007028)	heart left ventricle weight to body weight ratio (CMO:0000530)	7	43747099	102228765	Rat
7411607	Foco15	Food consumption QTL 15		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	7	75918751	120918751	Rat
634336	Anxrr17	Anxiety related response QTL 17	3.66		locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	7	924703	115097879	Rat
2293707	Bss32	Bone structure and strength QTL 32	7.64	0.0001	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	7	47651439	92651439	Rat
1331768	Kidm10	Kidney mass QTL 10	4.62096		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	7	80221299	125221299	Rat
61357	Bp38	Blood pressure QTL 38	1.6	0.052	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	41333674	119109060	Rat
1641908	Teswt1	Testicular weight QTL 1	3.28		testis mass (VT:1000644)	both testes wet weight (CMO:0000175)	7	80221299	94811326	Rat
2293644	Bmd29	Bone mineral density QTL 29	5.4	0.0001	femur size trait (VT:1000369)	femoral neck cross-sectional area (CMO:0001697)	7	47651439	92651439	Rat
2316947	Rf58	Renal function QTL 58	7.8		kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	7	68938720	113886318	Rat
2300178	Bmd54	Bone mineral density QTL 54	5.3	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	7	47651439	92651439	Rat
724537	Niddm52	Non-insulin dependent diabetes mellitus QTL 52		0.02	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	7	80221299	93595843	Rat
1298528	Bp169	Blood pressure QTL 169		0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	61074194	106074194	Rat
61428	Scl3	Serum cholesterol level QTL 3	3.2		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	7	44867533	89867533	Rat
1331746	Kidm9	Kidney mass QTL 9	3.934		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	7	80221299	112308525	Rat
1300132	Bp182	Blood pressure QTL 182	3.49		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	7	19654317	84928080	Rat
1576303	Ept7	Estrogen-induced pituitary tumorigenesis QTL 7	3.7		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	7	62004452	101773158	Rat
7411654	Foco25	Food consumption QTL 25	9.3	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	7	75918751	120918751	Rat
2316955	Stl24	Serum triglyceride level QTL 24	7.1		blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	7	68938720	113886318	Rat
2316952	Pur22	Proteinuria QTL 22	5.2		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	7	68938720	113886318	Rat
631540	Bw9	Body weight QTL 9	4.5		body mass (VT:0001259)	body weight (CMO:0000012)	7	69736226	117455174	Rat
1358891	Bp265	Blood pressure QTL 265	2.21		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	83591953	134666232	Rat

D7Rat141

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	83,591,953 - 83,592,070 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	91,832,949 - 91,833,065	NCBI	Rnor6.0
Rnor_5.0	7	92,475,985 - 92,476,101	UniSTS	Rnor5.0
RGSC_v3.4	7	88,583,730 - 88,583,847	RGD	RGSC3.4
RGSC_v3.4	7	88,583,731 - 88,583,847	UniSTS	RGSC3.4
RGSC_v3.1	7	88,604,461 - 88,604,577	RGD
Celera	7	80,455,311 - 80,455,427	UniSTS
RH 3.4 Map	7	573.4	RGD
RH 3.4 Map	7	573.4	UniSTS
RH 2.0 Map	7	490.3	RGD
SHRSP x BN Map	7	50.08	RGD
Cytogenetic Map	7	q31	UniSTS

This gene Slc30a8 is modified in the following models/strains:

SS-Slc30a8^em1Mcwi SS-Slc30a8^em2Mcwi

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	6	36	77	68	66	39	22	39	6	138	76	57	10	59	27


RefSeq Transcripts	NM_001130538	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006241645	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008765500	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473950	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000006410 ⟹ ENSRNOP00000006410

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	7	83,591,993 - 83,626,305 (+)	Ensembl
Rnor_6.0 Ensembl	7	91,832,988 - 91,865,774 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000079792 ⟹ ENSRNOP00000069455

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	7	91,833,297 - 91,867,300 (+)	Ensembl

RefSeq Acc Id:

NM_001130538 ⟹ NP_001124010

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	85,481,864 - 85,514,650 (+)	NCBI
mRatBN7.2	7	83,591,993 - 83,624,779 (+)	NCBI
Rnor_6.0	7	91,832,988 - 91,865,774 (+)	NCBI
Rnor_5.0	7	92,476,024 - 92,512,365 (+)	NCBI
RGSC_v3.4	7	88,583,770 - 88,617,145 (+)	RGD
Celera	7	80,455,350 - 80,488,134 (+)	RGD

Sequence:

show sequence

ATGTGTACACACACACACACACACACACACACACACACACTTTTTAGGATTCCATTTTCCAGTCTCCCAGAAAAGCAGTTTCTGTGGGTGATAGAATGAGTCCAAGTGATCATCCAAGAAGACCGTTA
ATTTTCACAGACCTACCAACAGCACTGATGTAGGACGCACTATTAACTCAAGTACTGGAAGGATTTTTCTATTTTCTTAGGAAGTTGTGTGAATATAATAATCTCAGTGCTTCTTTACTTCCAAAACT
GGACAGCAGGTCATATATCAAAAACAACAGTGTCAGCTCCTGTCCCTGCTACCATGGAGTTTCTTGAGAGGACTTACCTTGTGAATGATCAAGCCACCAAGATGTATGCCTTCACTTCAGACAGAGAA
CGTGGACAGAAGCCTGTGAATAAAGATCAGTGTCCTGGAGACGGGCCAGAGCGTCCGGAGGCAGGAGCCATCTATCACTGCCACAACAGCTTCAAGGCCACAGGGAACAGGTCGAGCAAGCAAGTGCA
TGCCAAGTGGAGACTCTGTGCTGCTTCAGCAATATGCTTCTTCTTTATGGTGGCAGAGGTGGTGGGTGGACATGTTGCTGGGAGTCTGGCGGTCCTCACTGATGCTGCTCATCTCTTAATTGACCTGA
CTAGTTTCCTGCTCAGTCTCTTTTCTTTGTGGTTATCTTCAAGGCCCCCTTCCAAGCGGCTGACATTTGGGTGGTATCGAGCAGAGATCCTCGGTGCCCTGCTGTCTGTCCTTTGCATCTGGGTGGTG
ACTGGTGTGCTGGTGTACCTTGCCTGTGAGCGCCTCTTGTATCCTGATTACCAGATCCAAGCAGGCATCATGATCACTGTTTCAGGCTGTGCAGTGGCAGCCAACATTGTACTAACTCTGATTTTGCA
CCAACGGCATCTTGGCCACAACCACAAGGATGCACAAGCTAATGCCAGCGTTCGAGCGGCCTTTGTGCATGCCCTGGGGGATGTGTTTCAGAGCACCAGTGTGCTAATTAGTGCTCTCATTATCTACT
TTAAGCCCGACTACAAAATGGCTGATCCAGTGTGCACATTTATCTCTTCCGTCTTGGCTTTGGCCAGCACCGTCATGATCTTAAAAGACTTCTCCATCTTACTCATGGAAGGTGTTCCAAAGGGCCTG
AGTTACAACAGTGTGAAAGAACTCCTCCTCACAGTCGATGGCGTGATCTCCGTGCACAATCTACACATCTGGTCGCTGACAGTGAACCAAGTGATTCTCTCTGTTCATGTTGCTACAGGTCAGTGA

hide sequence

RefSeq Acc Id:

XM_006241645 ⟹ XP_006241707

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	85,481,864 - 85,517,255 (+)	NCBI
mRatBN7.2	7	83,591,993 - 83,627,786 (+)	NCBI
Rnor_6.0	7	91,832,988 - 91,869,329 (+)	NCBI
Rnor_5.0	7	92,476,024 - 92,512,365 (+)	NCBI

Sequence:

show sequence

ATGTGTACACACACACACACACACACACACACACACACACTTTTTAGGATTCCATTTTCCAGTCTCCCAGAAAAGCAGTTTCTGTGGGTGATAGAATGAGTCCAAGTGATCATCCAAGAAGACCGTTA
ATTTTCACAGACCTACCAACAGCACTGATGTAGGACGCACTATTAACTCAAGTACTGGAAGGATTTTTCTATTTTCTTAGGAAGTTGTGTGAATATAATAATCTCAGTGCTTCTTTACTTCCAAAACT
GGACAGCAGGTCATATATCAAAAACAACAGTGTCAGCTCCTGTCCCTGCTACCATGGAGTTTCTTGAGAGGACTTACCTTGTGAATGATCAAGCCACCAAGATGTATGCCTTCACTTCAGACAGAGAA
CGTGGACAGAAGCCTGTGAATAAAGATCAGTGTCCTGGAGACGGGCCAGAGCGTCCGGAGGCAGGAGCCATCTATCACTGCCACAACAGCTTCAAGGCCACAGGGAACAGGTCGAGCAAGCAAGTGCA
TGCCAAGTGGAGACTCTGTGCTGCTTCAGCAATATGCTTCTTCTTTATGGTGGCAGAGGTGGTGGGTGGACATGTTGCTGGGAGTCTGGCGGTCCTCACTGATGCTGCTCATCTCTTAATTGACCTGA
CTAGTTTCCTGCTCAGTCTCTTTTCTTTGTGGTTATCTTCAAGGCCCCCTTCCAAGCGGCTGACATTTGGGTGGTATCGAGCAGAGATCCTCGGTGCCCTGCTGTCTGTCCTTTGCATCTGGGTGGTG
ACTGGTGTGCTGGTGTACCTTGCCTGTGAGCGCCTCTTGTATCCTGATTACCAGATCCAAGCAGGCATCATGATCACTGTTTCAGGCTGTGCAGTGGCAGCCAACATTGTACTAACTCTGATTTTGCA
CCAACGGCATCTTGGCCACAACCACAAGGATGCACAAGCTAATGCCAGCGTTCGAGCGGCCTTTGTGCATGCCCTGGGGGATGTGTTTCAGAGCACCAGTGTGCTAATTAGTGCTCTCATTATCTACT
TTAAGCCCGACTACAAAATGGCTGATCCAGTGTGCACATTTATCTCTTCCGTCTTGGCTTTGGCCAGCACCGTCATGATCTTAAAAGACTTCTCCATCTTACTCATGGAAGGTGTTCCAAAGGGCCTG
AGTTACAACAGTGTGAAAGAACTCCTCCTCACAGTCGATGGCGTGATCTCCGTGCACAATCTACACATCTGGTCGCTGACAGTGAACCAAGTGATTCTCTCTGTTCATGTTGCTACAGCTGCGAGCCA
GGACAGCCAGTCTGTGCGGACAGGAATTGCTTGCGCTCTCAGCAGTAGCTTTGATCTGCACTCTCTTACCATTCAGATCGAATCTGCGGCAGATCAGGACCCCAGCTGCCTTCTCTGTGAAGACCCAC
AGGACTAGCTCGCTCACTGTCAGCTTCCAGTGTTTCCTAGGCCATGATAAACTGCAGCAAAGTCTCTGCAATGCACAATTAAGCAACCAGCAGAACAGATTTGAGAAAATCATGACAATGCACTGTGC
ACGCTCTTCCATTGTGTTTGTCTCCATCCACCATGAATGAGGATGCATGGGCTTCATCAGCGTCTTGGATTACATACTTAATCAGTAGTCGTGCTCAATGATAGTATACATAGATTATTCCTAACTGG
GGTTGAAATAGCAGATGTTGGCCACCATAGGTAATGAATGACTCACTTCCCTACAGTAGTGGGTACAGCTGAATTCAGGAATGCCTTTGTAGGGATCCACAGCAGGAGAAACAAATATTTGAAGAGGA
TCTCGAGGCTTGGGGATTTGACTCTTGTGCCATCCTCAGTGAAATCTCCATTATTTGTGAAACAGTGAACCCCCCTTTTTATCTTGCATGTAAATTACGCTGTGAAGGATTGAATTATACTTTAATGC
TATGTGCAAAGGGTATGGAAAGTGGGAAAAATTTCTGAAATTGCTAACTTTTGAATGTTTTCATAAAGTAGAATTTAATAATGGAAGAAAACGAGGAGATGGCTTTTCTCCAGGTCACACACAAGGAA
ATTTAGTTTAAGAATTAAGATAACTCTCAAATTTTGCACACTATTCATGAATCACCATCATTCAATTGCTGTACTTTATTTCCCAACAAAATAACTTTTAGAATGTCAACTTATTACTATTTTTACTA
GGTAGACAGAACATAAAAATCAAAGAGGATCAGTAATTTTTAAAGTGTCATTTAGTCACAATTTTGATGCTAGACTTGGGAAGAGGGCAGGGGAAGAGCTTTTTTTATTTCTGTAACTGAATTATACT
GGGTCATTAAAAAGGAAACAGAACTTTATATAGCTCATGGCTCTGAAGGCTGGGAGTCTGTATGCGAGTGGCTGCTGCATGGGATGGTAATGGATGTGTGTAGAATCCCTAGGCAGAGCAGAGCATCA
TACGATGACAGGGACAAACATCTTGGCTTGCTTTTCTTCTTCATATAAAGCCACATTTTCACTGAATTAGGTCTCTGTGTTTGTGTTCCTTTTGAACATTACCTCCCAGTGGTTTTATCCGCCCAAAC
CCAGGTTTCTAGTCTCTCAAGAGTCCACCAGGGGCATTAAATTTCAACATTAGTTTTAGTGGGGTTGTTTAAACTGTTATCAGTGGACGGAGGTAACGTTAACACCGGCACAAATCGTGCTATTTTTC
TTGGGTTGGGGAGACATACACTATAGAGATAAAAACAACTGAGAAGTACTTTAAGAACTAGCCAATAATCTGAAGTAAGAGAGGCTGTGAGACTAAGGCAGGTCCATGAAGAATTTCTCAAAGAAAAC
CAAATTTGAAGGGAACAACAACAATAACAACAACAAATGTGTGTTAGCCAGATGGAATGTAGGAGGAGCCAGGATGGAATGTAGGAGGAGCCAGGATGGAATGTAGGAGGAGCCAGGATGGAATGTAG
GAGGAGCCAGATGGAATGTAGGAGAAGGCAGGATGGAATGTAGGAGGAGCCAGGATGGAATGTAGGAGGAGCCAGGATGGAATGTAGGAGGAGCCAGGATGGAATGTAGGAGGAGCCAGGATGGAATG
TAGGAGGAGCCAGGATGGAATGTAGGAGGAGCCAGGATGGAATGTAGGAGGAGCCAGGATGGAATGTAGGAGGAGGCAGGATGGGATGTAGGAGGAGCCAGGATCTATAAGAACCAAACCAGGTTGAA
ATCCATGCCACAAGAAGGTGCCCGCCTTTGACACTGCCTGGTCAGGGCAGGCTGGATAGCCCACAGACTTAAGATAGAACTAAACATGACTGGCAAATAAAAAAAGTCCTCGATGAAATGAAAACACA
CGGTTGCCACCCACATTAGAATAAAAACTAAACTCAGCATGTGTTGGTCCATTGCTTTAGTGAGCAGATCACCCTCTTGATCAAGAGTAAAGTTTTGCCTTGTTGCAAGAAACTTGA

hide sequence

RefSeq Acc Id:

XM_008765500 ⟹ XP_008763722

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	85,482,173 - 85,517,255 (+)	NCBI
mRatBN7.2	7	83,592,302 - 83,627,786 (+)	NCBI
Rnor_6.0	7	91,833,225 - 91,869,329 (+)	NCBI

Sequence:

show sequence

CTTCTTTACTTCCAAAACTGGACAGCAGGTCATATATCAAAAACAACAGTGTCAGCTCCTGTCCCTGCTACCATGGAGTTTCTTGAGAGGACTTACCTTGTGAATGATCAAGCCACCAAGATGTATGC
CTTCACTTCAGACAGCAGAGAACGTGGACAGAAGCCTGTGAATAAAGATCAGTGTCCTGGAGACGGGCCAGAGCGTCCGGAGGCAGGAGCCATCTATCACTGCCACAACAGCTTCAAGGCCACAGGGA
ACAGGTCGAGCAAGCAAGTGCATGCCAAGTGGAGACTCTGTGCTGCTTCAGCAATATGCTTCTTCTTTATGGTGGCAGAGGTGGTGGGTGGACATGTTGCTGGGAGTCTGGCGGTCCTCACTGATGCT
GCTCATCTCTTAATTGACCTGACTAGTTTCCTGCTCAGTCTCTTTTCTTTGTGGTTATCTTCAAGGCCCCCTTCCAAGCGGCTGACATTTGGGTGGTATCGAGCAGAGATCCTCGGTGCCCTGCTGTC
TGTCCTTTGCATCTGGGTGGTGACTGGTGTGCTGGTGTACCTTGCCTGTGAGCGCCTCTTGTATCCTGATTACCAGATCCAAGCAGGCATCATGATCACTGTTTCAGGCTGTGCAGTGGCAGCCAACA
TTGTACTAACTCTGATTTTGCACCAACGGCATCTTGGCCACAACCACAAGGATGCACAAGCTAATGCCAGCGTTCGAGCGGCCTTTGTGCATGCCCTGGGGGATGTGTTTCAGAGCACCAGTGTGCTA
ATTAGTGCTCTCATTATCTACTTTAAGCCCGACTACAAAATGGCTGATCCAGTGTGCACATTTATCTCTTCCGTCTTGGCTTTGGCCAGCACCGTCATGATCTTAAAAGACTTCTCCATCTTACTCAT
GGAAGGTGTTCCAAAGGGCCTGAGTTACAACAGTGTGAAAGAACTCCTCCTCACAGTCGATGGCGTGATCTCCGTGCACAATCTACACATCTGGTCGCTGACAGTGAACCAAGTGATTCTCTCTGTTC
ATGTTGCTACAGCTGCGAGCCAGGACAGCCAGTCTGTGCGGACAGGAATTGCTTGCGCTCTCAGCAGTAGCTTTGATCTGCACTCTCTTACCATTCAGATCGAATCTGCGGCAGATCAGGACCCCAGC
TGCCTTCTCTGTGAAGACCCACAGGACTAGCTCGCTCACTGTCAGCTTCCAGTGTTTCCTAGGCCATGATAAACTGCAGCAAAGTCTCTGCAATGCACAATTAAGCAACCAGCAGAACAGATTTGAGA
AAATCATGACAATGCACTGTGCACGCTCTTCCATTGTGTTTGTCTCCATCCACCATGAATGAGGATGCATGGGCTTCATCAGCGTCTTGGATTACATACTTAATCAGTAGTCGTGCTCAATGATAGTA
TACATAGATTATTCCTAACTGGGGTTGAAATAGCAGATGTTGGCCACCATAGGTAATGAATGACTCACTTCCCTACAGTAGTGGGTACAGCTGAATTCAGGAATGCCTTTGTAGGGATCCACAGCAGG
AGAAACAAATATTTGAAGAGGATCTCGAGGCTTGGGGATTTGACTCTTGTGCCATCCTCAGTGAAATCTCCATTATTTGTGAAACAGTGAACCCCCCTTTTTATCTTGCATGTAAATTACGCTGTGAA
GGATTGAATTATACTTTAATGCTATGTGCAAAGGGTATGGAAAGTGGGAAAAATTTCTGAAATTGCTAACTTTTGAATGTTTTCATAAAGTAGAATTTAATAATGGAAGAAAACGAGGAGATGGCTTT
TCTCCAGGTCACACACAAGGAAATTTAGTTTAAGAATTAAGATAACTCTCAAATTTTGCACACTATTCATGAATCACCATCATTCAATTGCTGTACTTTATTTCCCAACAAAATAACTTTTAGAATGT
CAACTTATTACTATTTTTACTAGGTAGACAGAACATAAAAATCAAAGAGGATCAGTAATTTTTAAAGTGTCATTTAGTCACAATTTTGATGCTAGACTTGGGAAGAGGGCAGGGGAAGAGCTTTTTTT
ATTTCTGTAACTGAATTATACTGGGTCATTAAAAAGGAAACAGAACTTTATATAGCTCATGGCTCTGAAGGCTGGGAGTCTGTATGCGAGTGGCTGCTGCATGGGATGGTAATGGATGTGTGTAGAAT
CCCTAGGCAGAGCAGAGCATCATACGATGACAGGGACAAACATCTTGGCTTGCTTTTCTTCTTCATATAAAGCCACATTTTCACTGAATTAGGTCTCTGTGTTTGTGTTCCTTTTGAACATTACCTCC
CAGTGGTTTTATCCGCCCAAACCCAGGTTTCTAGTCTCTCAAGAGTCCACCAGGGGCATTAAATTTCAACATTAGTTTTAGTGGGGTTGTTTAAACTGTTATCAGTGGACGGAGGTAACGTTAACACC
GGCACAAATCGTGCTATTTTTCTTGGGTTGGGGAGACATACACTATAGAGATAAAAACAACTGAGAAGTACTTTAAGAACTAGCCAATAATCTGAAGTAAGAGAGGCTGTGAGACTAAGGCAGGTCCA
TGAAGAATTTCTCAAAGAAAACCAAATTTGAAGGGAACAACAACAATAACAACAACAAATGTGTGTTAGCCAGATGGAATGTAGGAGGAGCCAGGATGGAATGTAGGAGGAGCCAGGATGGAATGTAG
GAGGAGCCAGGATGGAATGTAGGAGGAGCCAGATGGAATGTAGGAGAAGGCAGGATGGAATGTAGGAGGAGCCAGGATGGAATGTAGGAGGAGCCAGGATGGAATGTAGGAGGAGCCAGGATGGAATG
TAGGAGGAGCCAGGATGGAATGTAGGAGGAGCCAGGATGGAATGTAGGAGGAGCCAGGATGGAATGTAGGAGGAGCCAGGATGGAATGTAGGAGGAGGCAGGATGGGATGTAGGAGGAGCCAGGATCT
ATAAGAACCAAACCAGGTTGAAATCCATGCCACAAGAAGGTGCCCGCCTTTGACACTGCCTGGTCAGGGCAGGCTGGATAGCCCACAGACTTAAGATAGAACTAAACATGACTGGCAAATAAAAAAAG
TCCTCGATGAAATGAAAACACACGGTTGCCACCCACATTAGAATAAAAACTAAACTCAGCATGTGTTGGTCCATTGCTTTAGTGAGCAGATCACCCTCTTGATCAAGAGTAAAGTTTTGCCTTGTTGC
AAGAAACTTGA

hide sequence


Protein RefSeqs	NP_001124010	(Get FASTA)	NCBI Sequence Viewer
	XP_006241707	(Get FASTA)	NCBI Sequence Viewer
	XP_008763722	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM16273	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000006410
	ENSRNOP00000006410.7
GenBank Protein	P0CE46	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001124010 ⟸ NM_001130538

- UniProtKB:

P0CE46 (UniProtKB/Swiss-Prot), A0A0H2UHD4 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MEFLERTYLVNDQATKMYAFTSDRERGQKPVNKDQCPGDGPERPEAGAIYHCHNSFKATGNRSSKQVHAKWRLCAASAICFFFMVAEVVGGHVAGSLAVLTDAAHLLIDLTSFLLSLFSLWLSSRPPS
KRLTFGWYRAEILGALLSVLCIWVVTGVLVYLACERLLYPDYQIQAGIMITVSGCAVAANIVLTLILHQRHLGHNHKDAQANASVRAAFVHALGDVFQSTSVLISALIIYFKPDYKMADPVCTFISSV
LALASTVMILKDFSILLMEGVPKGLSYNSVKELLLTVDGVISVHNLHIWSLTVNQVILSVHVATGQ

hide sequence

RefSeq Acc Id:	XP_006241707 ⟸ XM_006241645
- Peptide Label:	isoform X1
- UniProtKB:	P0CE46 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MEFLERTYLVNDQATKMYAFTSDRERGQKPVNKDQCPGDGPERPEAGAIYHCHNSFKATGNRSSKQVHAKWRLCAASAICFFFMVAEVVGGHVAGSLAVLTDAAHLLIDLTSFLLSLFSLWLSSRPPS KRLTFGWYRAEILGALLSVLCIWVVTGVLVYLACERLLYPDYQIQAGIMITVSGCAVAANIVLTLILHQRHLGHNHKDAQANASVRAAFVHALGDVFQSTSVLISALIIYFKPDYKMADPVCTFISSV LALASTVMILKDFSILLMEGVPKGLSYNSVKELLLTVDGVISVHNLHIWSLTVNQVILSVHVATAASQDSQSVRTGIACALSSSFDLHSLTIQIESAADQDPSCLLCEDPQD hide sequence

RefSeq Acc Id:

XP_008763722 ⟸ XM_008765500

- Peptide Label:

isoform X2

- Sequence:

show sequence

MEFLERTYLVNDQATKMYAFTSDSRERGQKPVNKDQCPGDGPERPEAGAIYHCHNSFKATGNRSSKQVHAKWRLCAASAICFFFMVAEVVGGHVAGSLAVLTDAAHLLIDLTSFLLSLFSLWLSSRPP
SKRLTFGWYRAEILGALLSVLCIWVVTGVLVYLACERLLYPDYQIQAGIMITVSGCAVAANIVLTLILHQRHLGHNHKDAQANASVRAAFVHALGDVFQSTSVLISALIIYFKPDYKMADPVCTFISS
VLALASTVMILKDFSILLMEGVPKGLSYNSVKELLLTVDGVISVHNLHIWSLTVNQVILSVHVATAASQDSQSVRTGIACALSSSFDLHSLTIQIESAADQDPSCLLCEDPQD

hide sequence

Ensembl Acc Id:

ENSRNOP00000006410 ⟸ ENSRNOT00000006410

Ensembl Acc Id:

ENSRNOP00000069455 ⟸ ENSRNOT00000079792

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P0CE46-F1-model_v2	AlphaFold	P0CE46	1-368	view protein structure

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Database	Acc Id	Source(s)
BioCyc Gene	G2FUF-33421	BioCyc
Ensembl Genes	ENSRNOG00000004747	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000006410	ENTREZGENE
	ENSRNOT00000006410.7	UniProtKB/Swiss-Prot
Gene3D-CATH	1.20.1510.10	UniProtKB/Swiss-Prot
InterPro	Cation_efflux	UniProtKB/Swiss-Prot
	Cation_efflux_CTD_sf	UniProtKB/Swiss-Prot
	Cation_efflux_TMD_sf	UniProtKB/Swiss-Prot
	CDF/SLC30A	UniProtKB/Swiss-Prot
KEGG Report	rno:299903	UniProtKB/Swiss-Prot
NCBI Gene	299903	ENTREZGENE
PANTHER	CATION EFFLUX PROTEIN/ ZINC TRANSPORTER	UniProtKB/Swiss-Prot
	PTHR11562:SF37	UniProtKB/Swiss-Prot
Pfam	Cation_efflux	UniProtKB/Swiss-Prot
PhenoGen	Slc30a8	PhenoGen
RatGTEx	ENSRNOG00000004747	RatGTEx
Superfamily-SCOP	SSF160240	UniProtKB/Swiss-Prot
	SSF161111	UniProtKB/Swiss-Prot
UniProt	A0A0H2UHD4	ENTREZGENE
	P0CE46	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-04-30	Slc30a8	solute carrier family 30 (zinc transporter), member 8	Slc30a8_predicted	solute carrier family 30 (zinc transporter), member 8 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Slc30a8_predicted	solute carrier family 30 (zinc transporter), member 8 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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Imported Disease Annotations - CTD

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