LOC120103162 (interferon alpha-1-like) - Rat Genome Database

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Gene: LOC120103162 (interferon alpha-1-like) Rattus norvegicus
Analyze
No known orthologs.
Symbol: LOC120103162
Name: interferon alpha-1-like
RGD ID: 40975974
Description: Predicted to enable cytokine activity and type I interferon receptor binding activity. Predicted to be involved in several processes, including lymphocyte activation involved in immune response; response to exogenous dsRNA; and type I interferon-mediated signaling pathway. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in Crimean-Congo hemorrhagic fever; common cold; hepatitis B; liver disease (multiple); and sarcoidosis. Orthologous to several human genes including IFNA1 (interferon alpha 1); IFNA10 (interferon alpha 10); and IFNA13 (interferon alpha 13).
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85108,571,170 - 108,571,724 (+)NCBIGRCr8
mRatBN7.25103,455,380 - 103,455,934 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5103,455,380 - 103,455,934 (+)EnsemblmRatBN7.2 Ensembl
Cytogenetic Map5q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



Biological Process
1 to 11 of 11 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
LOC120103162Ratadaptive immune response involved_inIBAMGI:107657|PANTHER:PTN0026186441600115GO_REF:0000033GO_CentralGO_REF:0000033
LOC120103162RatB cell activation involved in immune response involved_inIBAPANTHER:PTN002618644|UniProtKB:P015741600115GO_REF:0000033GO_CentralGO_REF:0000033
LOC120103162Ratdefense response involved_inIEAInterPro:IPR0004711600115GO_REF:0000002InterProGO_REF:0000002
LOC120103162Ratdefense response to virus involved_inIEAUniProtKB-KW:KW-00511600115GO_REF:0000043UniProtGO_REF:0000043
LOC120103162Rathumoral immune response involved_inIBAMGI:107657|PANTHER:PTN0026186441600115GO_REF:0000033GO_CentralGO_REF:0000033
LOC120103162Ratnatural killer cell activation involved in immune response involved_inIBAMGI:107659|MGI:107664|MGI:107668|PANTHER:PTN0026186441600115GO_REF:0000033GO_CentralGO_REF:0000033
LOC120103162Ratresponse to exogenous dsRNA involved_inIBAPANTHER:PTN002618644|RGD:2865|UniProtKB:P01574|ZFIN:ZDB-GENE-030721-31600115GO_REF:0000033GO_CentralGO_REF:0000033
LOC120103162Ratresponse to stress involved_inIEAARBA:ARBA000263001600115GO_REF:0000117UniProtGO_REF:0000117
LOC120103162Ratresponse to virus involved_inIEAARBA:ARBA000264921600115GO_REF:0000117UniProtGO_REF:0000117
LOC120103162RatT cell activation involved in immune response involved_inIBAMGI:107668|PANTHER:PTN0026186441600115GO_REF:0000033GO_CentralGO_REF:0000033
LOC120103162Rattype I interferon-mediated signaling pathway involved_inIBAMGI:107657|MGI:107668|PANTHER:PTN002618644|UniProtKB:P01563|UniProtKB:P015741600115GO_REF:0000033GO_CentralGO_REF:0000033
1 to 11 of 11 rows

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
LOC120103162Ratextracellular region located_inIEAUniProtKB-KW:KW-09641600115GO_REF:0000043UniProtGO_REF:0000043
LOC120103162Ratextracellular region located_inIEAInterPro:IPR0004711600115GO_REF:0000002InterProGO_REF:0000002
LOC120103162Ratextracellular region located_inIEAUniProtKB-SubCell:SL-02431600115GO_REF:0000044UniProtGO_REF:0000044
LOC120103162Ratextracellular space located_inIEAUniProtKB-KW:KW-02021600115GO_REF:0000043UniProtGO_REF:0000043
LOC120103162Ratextracellular space is_active_inIBAMGI:107657|MGI:107659|MGI:107662|MGI:107664|MGI:107668|PANTHER:PTN000190054|UniProtKB:P01563|UniProtKB:P015741600115GO_REF:0000033GO_CentralGO_REF:0000033

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
LOC120103162Ratcytokine activity enablesIBAMGI:107657|MGI:107668|PANTHER:PTN000190054|UniProtKB:P01563|UniProtKB:P015741600115GO_REF:0000033GO_CentralGO_REF:0000033
LOC120103162Ratcytokine activity enablesIEAUniProtKB-KW:KW-02021600115GO_REF:0000043UniProtGO_REF:0000043
LOC120103162Ratcytokine receptor binding enablesIEAInterPro:IPR0004711600115GO_REF:0000002InterProGO_REF:0000002
LOC120103162Rattype I interferon receptor binding enablesIBAMGI:107657|MGI:2448469|PANTHER:PTN000190054|UniProtKB:Q9P0W01600115GO_REF:0000033GO_CentralGO_REF:0000033



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Variants in LOC120103162
7 total Variants

1 to 10 of 43 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1357396Bw44Body weight QTL 444.19body mass (VT:0001259)body weight (CMO:0000012)568984307104251008Rat
1331796Thshl2Thyroid stimulating hormone level QTL 22.3blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)597059760147465714Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
61380Edpm5Estrogen-dependent pituitary mass QTL 54.50.92pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)568984307104251008Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51131345958Rat
1298070Scl18Serum cholesterol level QTL 183.7blood LDL cholesterol amount (VT:0000181)calculated plasma low density lipoprotein cholesterol level (CMO:0001245)579584860124584860Rat
634305Mamtr1Mammary tumor resistance QTL 10.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)512789751113558310Rat
61452Ciaa5CIA Autoantibody QTL 53.5blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)594858972143070159Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)543726656129132602Rat
1357402Bw46Body weight QTL 464.47body mass (VT:0001259)body mass index (BMI) (CMO:0000105)568984307104251008Rat

1 to 10 of 43 rows





RefSeq Transcripts XM_039111557 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000100928   ⟹   ENSRNOP00000079230
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5103,455,380 - 103,455,934 (+)Ensembl
RefSeq Acc Id: XM_039111557   ⟹   XP_038967485
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85108,571,170 - 108,571,724 (+)NCBI
mRatBN7.25103,455,380 - 103,455,934 (+)NCBI
Protein RefSeqs XP_038967485 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000079230.1
RefSeq Acc Id: XP_038967485   ⟸   XM_039111557
- UniProtKB: A0A8I5ZN08 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000079230   ⟸   ENSRNOT00000100928


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 17 of 17 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-40801 BioCyc
Ensembl Genes ENSRNOG00000065583 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000100928.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1250.10 UniProtKB/TrEMBL
InterPro 4_helix_cytokine-like_core UniProtKB/TrEMBL
  Interferon_alpha/beta/delta UniProtKB/TrEMBL
NCBI Gene LOC120103162 ENTREZGENE
PANTHER ALPHA-INTERFERON-RELATED UniProtKB/TrEMBL
  PTHR11691 UniProtKB/TrEMBL
Pfam Interferon UniProtKB/TrEMBL
PhenoGen LOC120103162 PhenoGen
PRINTS INTERFERONAB UniProtKB/TrEMBL
PROSITE INTERFERON_A_B_D UniProtKB/TrEMBL
RatGTEx ENSRNOG00000065583 RatGTEx
SMART IFabd UniProtKB/TrEMBL
Superfamily-SCOP SSF47266 UniProtKB/TrEMBL
UniProt A0A8I5ZN08 ENTREZGENE, UniProtKB/TrEMBL
1 to 17 of 17 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-01-26 LOC120103162  interferon alpha-1-like      Symbol and Name status set to provisional 70820 PROVISIONAL