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Gene: B4GALT1 (beta-1,4-galactosyltransferase 1) Homo sapiens
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Symbol: B4GALT1
Name: beta-1,4-galactosyltransferase 1
Description: Exhibits several functions, including UDP-galactosyltransferase activity; manganese ion binding activity; and tubulin binding activity. Involved in oligosaccharide biosynthetic process; protein N-linked glycosylation; and protein homooligomerization. Localizes to several cellular components, including the Golgi trans cisterna; basolateral plasma membrane; and brush border membrane. Implicated in congenital disorder of glycosylation and congenital disorder of glycosylation type IId.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: B4GAL-T1; beta-1,4-GalTase 1; beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase; beta4Gal-T1; CDG2D; DKFZp686N19253; GGTB2; glycoprotein-4-beta-galactosyltransferase 2; GT1; GTB; lactose synthase; MGC50983; N-acetyllactosamine synthase; nal synthase; UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 1; UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1; UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 1
Orthologs:
Mus musculus (house mouse) : B4galt1 (UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : B4galt1 (beta-1,4-galactosyltransferase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : B4galt1 (beta-1,4-galactosyltransferase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : B4GALT1 (beta-1,4-galactosyltransferase 1)
Canis lupus familiaris (dog) : B4GALT1 (beta-1,4-galactosyltransferase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : B4galt1 (beta-1,4-galactosyltransferase 1)
Sus scrofa (pig) : B4GALT1 (beta-1,4-galactosyltransferase 1)
Chlorocebus sabaeus (African green monkey) : B4GALT1 (beta-1,4-galactosyltransferase 1)
Heterocephalus glaber (naked mole-rat) : B4galt1 (beta-1,4-galactosyltransferase 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl933,104,082 - 33,167,356 (-)Ensembl
GRCh38933,110,641 - 33,167,358 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37933,110,636 - 33,167,356 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36933,100,642 - 33,157,236 (-)NCBINCBI36hg18NCBI36
Build 34933,100,641 - 33,157,231NCBI
Celera933,041,647 - 33,098,362 (-)NCBI
Cytogenetic Map9p21.1NCBI
HuRef933,068,632 - 33,125,120 (-)NCBIHuRef
CHM1_1933,110,422 - 33,167,124 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
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Sequence

Nucleotide Sequences
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Nomenclature History
 
More on B4GALT1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1349315
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.