Echdc2 (enoyl CoA hydratase domain containing 2) - Rat Genome Database

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Gene: Echdc2 (enoyl CoA hydratase domain containing 2) Rattus norvegicus
Analyze
Symbol: Echdc2
Name: enoyl CoA hydratase domain containing 2
RGD ID: 1308525
Description: Predicted to enable lyase activity. Predicted to be involved in fatty acid beta-oxidation. Predicted to be active in mitochondrion. Orthologous to human ECHDC2 (enoyl-CoA hydratase domain containing 2); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: enoyl Coenzyme A hydratase domain containing 2; enoyl-CoA hydratase domain-containing protein 2, mitochondrial; LOC298381; RGD1308525; similar to hypothetical protein D4Ertd765e
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85128,144,241 - 128,163,611 (+)NCBIGRCr8
mRatBN7.25122,915,874 - 122,934,860 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5122,916,134 - 122,934,859 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5125,534,346 - 125,547,333 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05127,257,395 - 127,270,382 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05127,308,713 - 127,321,700 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05127,770,570 - 127,789,568 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5127,770,570 - 127,789,567 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05131,618,513 - 131,638,156 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45129,265,272 - 129,284,240 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15129,274,219 - 129,289,467 (+)NCBI
Celera5121,659,440 - 121,672,312 (+)NCBICelera
Cytogenetic Map5q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
(+)-schisandrin B  (EXP)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
belinostat  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
chlordecone  (ISO)
chlorpyrifos  (ISO)
cisplatin  (ISO)
clofibric acid  (EXP)
cobalt dichloride  (EXP)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
entinostat  (ISO)
epoxiconazole  (ISO)
fenthion  (ISO)
folic acid  (ISO)
hydrogen peroxide  (ISO)
methamphetamine  (ISO)
methidathion  (ISO)
methoxychlor  (EXP)
N-nitrosodiethylamine  (EXP)
nickel atom  (ISO)
niclosamide  (ISO)
ozone  (ISO)
paracetamol  (ISO)
paraquat  (EXP)
perfluorononanoic acid  (ISO)
phenobarbital  (EXP)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
progesterone  (ISO)
propiconazole  (EXP)
SB 431542  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloroethene  (ISO)
tetrachloromethane  (EXP,ISO)
tetraphene  (ISO)
thimerosal  (ISO)
thioacetamide  (EXP)
trichloroethene  (EXP)
Triptolide  (EXP)
triptonide  (ISO)
troglitazone  (EXP)
trovafloxacin  (ISO)
valproic acid  (ISO)
vitamin E  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
mitochondrion  (IBA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:34800366  


Genomics

Comparative Map Data
Echdc2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85128,144,241 - 128,163,611 (+)NCBIGRCr8
mRatBN7.25122,915,874 - 122,934,860 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5122,916,134 - 122,934,859 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5125,534,346 - 125,547,333 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05127,257,395 - 127,270,382 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05127,308,713 - 127,321,700 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05127,770,570 - 127,789,568 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5127,770,570 - 127,789,567 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05131,618,513 - 131,638,156 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45129,265,272 - 129,284,240 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15129,274,219 - 129,289,467 (+)NCBI
Celera5121,659,440 - 121,672,312 (+)NCBICelera
Cytogenetic Map5q34NCBI
ECHDC2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38152,895,910 - 52,921,774 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl152,895,910 - 52,927,212 (-)EnsemblGRCh38hg38GRCh38
GRCh37153,361,582 - 53,387,446 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36153,134,492 - 53,160,034 (-)NCBINCBI36Build 36hg18NCBI36
Build 34153,073,925 - 53,099,419NCBI
Celera151,649,717 - 51,675,255 (-)NCBICelera
Cytogenetic Map1p32.3NCBI
HuRef151,477,347 - 51,503,011 (-)NCBIHuRef
CHM1_1153,478,780 - 53,504,616 (-)NCBICHM1_1
T2T-CHM13v2.0152,777,434 - 52,803,290 (-)NCBIT2T-CHM13v2.0
Echdc2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394108,022,630 - 108,036,505 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4108,022,634 - 108,036,505 (+)EnsemblGRCm39 Ensembl
GRCm384108,165,436 - 108,179,308 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4108,165,437 - 108,179,308 (+)EnsemblGRCm38mm10GRCm38
MGSCv374107,838,071 - 107,851,913 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364107,663,428 - 107,677,239 (+)NCBIMGSCv36mm8
Celera4106,508,736 - 106,522,604 (+)NCBICelera
Cytogenetic Map4C7NCBI
cM Map450.3NCBI
Echdc2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554646,284,436 - 6,300,908 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554646,284,436 - 6,300,908 (+)NCBIChiLan1.0ChiLan1.0
ECHDC2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21173,915,096 - 173,946,810 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11173,057,348 - 173,089,056 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0152,163,918 - 52,195,629 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1153,766,197 - 53,792,466 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl153,766,197 - 53,792,248 (-)Ensemblpanpan1.1panPan2
ECHDC2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1555,972,116 - 55,991,573 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl555,972,004 - 55,991,531 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha556,037,636 - 56,057,294 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0556,161,679 - 56,181,408 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl556,160,574 - 56,207,746 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1556,153,036 - 56,172,685 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0556,044,711 - 56,064,447 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0556,434,422 - 56,454,151 (+)NCBIUU_Cfam_GSD_1.0
Echdc2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505867,275,962 - 67,293,555 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365228,122,351 - 8,143,884 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365228,122,748 - 8,139,940 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ECHDC2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6159,326,150 - 159,347,173 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16159,326,146 - 159,347,178 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26146,951,363 - 146,966,597 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ECHDC2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12080,017,665 - 80,043,810 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2080,017,421 - 80,044,670 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603337,235,452 - 37,261,600 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Echdc2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624859283,412 - 299,489 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624859283,436 - 299,489 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:269
Count of miRNA genes:168
Interacting mature miRNAs:183
Transcripts:ENSRNOT00000047653
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331796Thshl2Thyroid stimulating hormone level QTL 22.3blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)5102105698152749382Rat
2303586Gluco52Glucose level QTL 522blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)5100826632145826632Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)544924861153890773Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5116702075161702075Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)538207390136631402Rat
1298070Scl18Serum cholesterol level QTL 183.7blood LDL cholesterol amount (VT:0000181)calculated plasma low density lipoprotein cholesterol level (CMO:0001245)584630798129630798Rat
61452Ciaa5CIA Autoantibody QTL 53.5blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)599905133172190305Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)548523123134369373Rat
1582230Bw78Body weight QTL 783.20.0016epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)5124314582133270832Rat
7411582Foco3Food consumption QTL 37.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)592583776137583776Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)565089051166764498Rat
1598859Cm66Cardiac mass QTL 662heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)584630798129630798Rat
7207486Bss109Bone structure and strength QTL 109femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)5112142946157142946Rat
7207481Bss106Bone structure and strength QTL 1067.9femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5112142946157142946Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5110770739155770739Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)551657967166600247Rat
1549838Bss4Bone structure and strength QTL 49.2femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)5112142946157142946Rat
7411564Bw135Body weight QTL 1350.001body mass (VT:0001259)body weight gain (CMO:0000420)592583776137583776Rat
8657050Bw146Body weight QTL 14619.840.001body mass (VT:0001259)body weight gain (CMO:0000420)598972960143972960Rat
1581510Cm54Cardiac mass QTL 543.40.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)5125969677172190305Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555124766172190305Rat
7411601Foco12Food consumption QTL 1219.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)592583776137583776Rat
2303618Vencon1Ventilatory control QTL 13.8respiration trait (VT:0001943)oxygen consumption (CMO:0002169)5100826632145826632Rat
2317056Wbc3White blood cell count QTL 32.510.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)5111236572156236572Rat
1598846Bp293Blood pressure QTL 2933.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)584630798129630798Rat
7394710Emca12Estrogen-induced mammary cancer QTL 12mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)594034903139034903Rat
1598847Cm62Cardiac mass QTL 623.4heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5114131300159131300Rat
2293642Bss37Bone structure and strength QTL 374.640.0001femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5125969677156302135Rat
1358909Kidm25Kidney mass QTL 251.87kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)595062526133270832Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)560601597137492949Rat
7207488Bss110Bone structure and strength QTL 18.4femur strength trait (VT:0010010)femur stiffness (CMO:0001674)5112142946157142946Rat
8694441Bw169Body weight QTL 16917.610.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)5116702075161702075Rat
7207491Bss112Bone structure and strength QTL 1127femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)5112142946157142946Rat
8694389Bw160Body weight QTL 1606.170.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)5116702075161702075Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)536460764136631402Rat
1354598Srn6Serum renin concentration QTL 63.8blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)574335621156302135Rat
8694198Abfw3Abdominal fat weight QTL 316.130.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)5116702075161702075Rat
1298086Bp156Blood pressure QTL 156arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)589369373134369373Rat
2306971Anxrr21Anxiety related response QTL 219.47fear/anxiety-related behavior trait (VT:1000241)number of entries into a discrete space in an experimental apparatus (CMO:0000960)570969494136328156Rat
1298089Scl14Serum cholesterol level QTL 145.80.0004blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5114131300159131300Rat
1358895Bp254Blood pressure QTL 2543.60.0003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)597492524133270832Rat
6903316Bw113Body weight QTL 11320.0103body mass (VT:0001259)body weight (CMO:0000012)592881678137881678Rat
1358889Bp261Blood pressure QTL 2612.86arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)595062526133270832Rat
1358187Emca1Estrogen-induced mammary cancer QTL 14.4mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)5104262817153890625Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000047653   ⟹   ENSRNOP00000049726
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5122,916,134 - 122,934,859 (+)Ensembl
Rnor_6.0 Ensembl5127,770,570 - 127,789,567 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000096852   ⟹   ENSRNOP00000082488
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5122,916,134 - 122,927,863 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000102891   ⟹   ENSRNOP00000077778
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5122,916,134 - 122,925,093 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000109970   ⟹   ENSRNOP00000092153
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5122,916,134 - 122,934,859 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000119614   ⟹   ENSRNOP00000081427
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5122,916,134 - 122,934,859 (+)Ensembl
RefSeq Acc Id: NM_001106675   ⟹   NP_001100145
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85128,144,886 - 128,163,610 (+)NCBI
mRatBN7.25122,916,134 - 122,934,859 (+)NCBI
Rnor_6.05127,770,570 - 127,789,567 (+)NCBI
Rnor_5.05131,618,513 - 131,638,156 (+)NCBI
RGSC_v3.45129,265,272 - 129,284,240 (+)RGD
Celera5121,659,440 - 121,672,312 (+)RGD
Sequence:
RefSeq Acc Id: XM_006238507   ⟹   XP_006238569
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85128,148,378 - 128,163,611 (+)NCBI
mRatBN7.25122,919,626 - 122,934,860 (+)NCBI
Rnor_6.05127,774,056 - 127,789,568 (+)NCBI
Rnor_5.05131,618,513 - 131,638,156 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039109577   ⟹   XP_038965505
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85128,144,500 - 128,163,611 (+)NCBI
mRatBN7.25122,915,875 - 122,934,860 (+)NCBI
RefSeq Acc Id: XM_063287394   ⟹   XP_063143464
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85128,144,241 - 128,158,135 (+)NCBI
RefSeq Acc Id: XM_063287395   ⟹   XP_063143465
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85128,144,241 - 128,158,135 (+)NCBI
RefSeq Acc Id: XR_005504398
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85128,144,491 - 128,163,225 (+)NCBI
mRatBN7.25122,915,874 - 122,934,860 (+)NCBI
RefSeq Acc Id: XR_005504399
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85128,144,491 - 128,163,178 (+)NCBI
mRatBN7.25122,915,874 - 122,934,431 (+)NCBI
RefSeq Acc Id: XR_005504400
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85128,144,494 - 128,163,178 (+)NCBI
mRatBN7.25122,915,875 - 122,934,431 (+)NCBI
RefSeq Acc Id: NP_001100145   ⟸   NM_001106675
- UniProtKB: D3ZIL6 (UniProtKB/TrEMBL),   A6JYU2 (UniProtKB/TrEMBL),   A0A8I5ZUZ9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006238569   ⟸   XM_006238507
- Peptide Label: isoform X3
- UniProtKB: A6JYU3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000049726   ⟸   ENSRNOT00000047653
RefSeq Acc Id: XP_038965505   ⟸   XM_039109577
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZUZ9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000082488   ⟸   ENSRNOT00000096852
Ensembl Acc Id: ENSRNOP00000077778   ⟸   ENSRNOT00000102891
Ensembl Acc Id: ENSRNOP00000092153   ⟸   ENSRNOT00000109970
Ensembl Acc Id: ENSRNOP00000081427   ⟸   ENSRNOT00000119614
RefSeq Acc Id: XP_063143464   ⟸   XM_063287394
- Peptide Label: isoform X1
- UniProtKB: A0A8I5Y213 (UniProtKB/TrEMBL),   A0A8I5ZV01 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063143465   ⟸   XM_063287395
- Peptide Label: isoform X1
- UniProtKB: A0A8I5Y213 (UniProtKB/TrEMBL),   A0A8I5ZV01 (UniProtKB/TrEMBL)
Protein Domains
Enoyl-CoA hydratase/isomerase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZIL6-F1-model_v2 AlphaFold D3ZIL6 1-296 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693899
Promoter ID:EPDNEW_R4423
Type:initiation region
Name:Echdc2_1
Description:enoyl CoA hydratase domain containing 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05127,770,577 - 127,770,637EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308525 AgrOrtholog
BioCyc Gene G2FUF-40394 BioCyc
Ensembl Genes ENSRNOG00000029333 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000047653.4 UniProtKB/TrEMBL
  ENSRNOT00000096852.1 UniProtKB/TrEMBL
  ENSRNOT00000102891.1 UniProtKB/TrEMBL
  ENSRNOT00000109970.1 UniProtKB/TrEMBL
  ENSRNOT00000119614.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.12.10 UniProtKB/TrEMBL
InterPro ClpP/crotonase-like_dom UniProtKB/TrEMBL
  Crontonase_C UniProtKB/TrEMBL
  Crotonase_core UniProtKB/TrEMBL
  ECH_dom UniProtKB/TrEMBL
  Enoyl-CoA_hyd/isom_CS UniProtKB/TrEMBL
KEGG Report rno:298381 UniProtKB/TrEMBL
NCBI Gene 298381 ENTREZGENE
PANTHER ENOYL-COA HYDRATASE DOMAIN-CONTAINING PROTEIN 2, MITOCHONDRIAL UniProtKB/TrEMBL
  ENOYL-COA HYDRATASE-RELATED UniProtKB/TrEMBL
Pfam ECH UniProtKB/TrEMBL
  ECH_2 UniProtKB/TrEMBL
PhenoGen Echdc2 PhenoGen
PROSITE ENOYL_COA_HYDRATASE UniProtKB/TrEMBL
RatGTEx ENSRNOG00000029333 RatGTEx
Superfamily-SCOP SSF52096 UniProtKB/TrEMBL
UniProt A0A8I5Y213 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZUZ9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZV01 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AGL7_RAT UniProtKB/TrEMBL
  A6JYU2 ENTREZGENE, UniProtKB/TrEMBL
  A6JYU3 ENTREZGENE, UniProtKB/TrEMBL
  D3ZIL6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-08-02 Echdc2  enoyl CoA hydratase domain containing 2  Echdc2  enoyl Coenzyme A hydratase domain containing 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Echdc2  enoyl Coenzyme A hydratase domain containing 2   Echdc2_predicted  enoyl Coenzyme A hydratase domain containing 2 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Echdc2_predicted  enoyl Coenzyme A hydratase domain containing 2 (predicted)  RGD1308525_predicted  similar to hypothetical protein D4Ertd765e (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-20 RGD1308525_predicted  similar to hypothetical protein D4Ertd765e (predicted)  LOC298381_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC298381_predicted  similar to hypothetical protein D4Ertd765e (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL