PTPRZ1 (protein tyrosine phosphatase receptor type Z1) - Rat Genome Database

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Gene: PTPRZ1 (protein tyrosine phosphatase receptor type Z1) Canis lupus familiaris
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Symbol: PTPRZ1
Name: protein tyrosine phosphatase receptor type Z1
RGD ID: 12223899
Description: ENCODES a protein that exhibits fibroblast growth factor binding (ortholog); phosphatase activity (ortholog); protein tyrosine phosphatase activity (ortholog); INVOLVED IN axonal fasciculation (ortholog); axonogenesis (ortholog); brain development (ortholog); ASSOCIATED WITH amyotrophic lateral sclerosis (ortholog); Brain Injuries (ortholog); Helicobacter Infections (ortholog); FOUND IN axon (ortholog); cytoplasm (ortholog); dendrite (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase zeta; protein tyrosine phosphatase, receptor-type, Z polypeptide 1; receptor-type tyrosine-protein phosphatase zeta
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11459,769,553 - 59,944,111 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1459,827,650 - 59,943,315 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1459,203,408 - 59,361,617 (+)NCBI
ROS_Cfam_1.01459,825,102 - 59,979,392 (+)NCBI
UMICH_Zoey_3.11459,916,795 - 60,071,051 (+)NCBI
UNSW_CanFamBas_1.01459,543,462 - 59,698,673 (+)NCBI
UU_Cfam_GSD_1.01459,919,950 - 60,076,006 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

Genomics

Comparative Map Data
PTPRZ1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11459,769,553 - 59,944,111 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1459,827,650 - 59,943,315 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1459,203,408 - 59,361,617 (+)NCBI
ROS_Cfam_1.01459,825,102 - 59,979,392 (+)NCBI
UMICH_Zoey_3.11459,916,795 - 60,071,051 (+)NCBI
UNSW_CanFamBas_1.01459,543,462 - 59,698,673 (+)NCBI
UU_Cfam_GSD_1.01459,919,950 - 60,076,006 (+)NCBI
PTPRZ1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl7121,873,089 - 122,062,036 (+)EnsemblGRCh38hg38GRCh38
GRCh387121,873,161 - 122,062,036 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh377121,513,215 - 121,702,090 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367121,300,395 - 121,489,326 (+)NCBINCBI36hg18NCBI36
Build 347121,107,357 - 121,296,039NCBI
Celera7116,322,385 - 116,511,311 (+)NCBI
Cytogenetic Map7q31.32NCBI
HuRef7115,876,018 - 116,065,533 (+)NCBIHuRef
CHM1_17121,446,481 - 121,635,390 (+)NCBICHM1_1
CRA_TCAGchr7v27120,907,807 - 121,096,757 (+)NCBI
Ptprz1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39622,875,302 - 23,052,915 (+)NCBIGRCm39mm39
GRCm39 Ensembl622,875,501 - 23,052,915 (+)Ensembl
GRCm38622,875,315 - 23,052,916 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl622,875,502 - 23,052,916 (+)EnsemblGRCm38mm10GRCm38
MGSCv37622,825,502 - 23,002,916 (+)NCBIGRCm37mm9NCBIm37
MGSCv36622,825,503 - 23,002,917 (+)NCBImm8
Celera622,923,288 - 23,100,277 (+)NCBICelera
Cytogenetic Map6A3.1NCBI
Ptprz1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2451,397,316 - 51,595,220 (+)NCBI
Rnor_6.0 Ensembl449,941,304 - 50,140,762 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0449,941,046 - 50,140,764 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0449,730,302 - 49,927,328 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4449,267,521 - 49,468,692 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1449,498,094 - 49,699,266 (+)NCBI
Celera446,598,237 - 46,787,500 (+)NCBICelera
Cytogenetic Map4q22NCBI
Ptprz1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554793,624,993 - 3,733,183 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554793,611,658 - 3,734,225 (+)NCBIChiLan1.0ChiLan1.0
PTPRZ1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.17126,569,630 - 126,758,155 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7126,569,630 - 126,758,155 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v07113,882,557 - 114,073,283 (+)NCBIMhudiblu_PPA_v0panPan3
Ptprz1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511848,835,842 - 49,007,255 (+)NCBI
SpeTri2.0NW_0049366053,195,893 - 3,368,102 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PTPRZ1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1825,045,727 - 25,228,247 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11825,046,027 - 25,228,276 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21826,650,579 - 26,832,837 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PTPRZ1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12190,686,091 - 90,877,538 (+)NCBI
ChlSab1.1 Ensembl2190,686,167 - 90,877,649 (+)Ensembl
Ptprz1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462478313,911,525 - 14,105,403 (-)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 1 1 7
Low 4 16 1 3 1 5 5 8 5
Below cutoff 1 5 5 5 3 5 6 5 6

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000005646   ⟹   ENSCAFP00000005230
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1459,828,237 - 59,943,315 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000045335   ⟹   ENSCAFP00000038572
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1459,828,237 - 59,943,315 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000061948   ⟹   ENSCAFP00000058615
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1459,827,650 - 59,943,315 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000068657   ⟹   ENSCAFP00000043960
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1459,870,806 - 59,943,315 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000078719   ⟹   ENSCAFP00000059908
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1459,915,407 - 59,943,315 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000092091   ⟹   ENSCAFP00000052052
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1459,828,237 - 59,943,315 (+)Ensembl
RefSeq Acc Id: XM_022427173   ⟹   XP_022282881
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11459,769,553 - 59,944,111 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038434751   ⟹   XP_038290679
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1459,203,408 - 59,361,617 (+)NCBI
RefSeq Acc Id: XM_038494101   ⟹   XP_038350029
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11459,916,795 - 60,071,051 (+)NCBI
RefSeq Acc Id: XM_038556356   ⟹   XP_038412284
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01459,919,950 - 60,076,006 (+)NCBI
RefSeq Acc Id: XM_038620283   ⟹   XP_038476211
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01459,543,462 - 59,698,673 (+)NCBI
RefSeq Acc Id: XM_038685960   ⟹   XP_038541888
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01459,825,102 - 59,979,392 (+)NCBI
Reference Sequences
RefSeq Acc Id: XP_022282881   ⟸   XM_022427173
- Sequence:
RefSeq Acc Id: ENSCAFP00000005230   ⟸   ENSCAFT00000005646
RefSeq Acc Id: ENSCAFP00000059908   ⟸   ENSCAFT00000078719
RefSeq Acc Id: ENSCAFP00000038572   ⟸   ENSCAFT00000045335
RefSeq Acc Id: ENSCAFP00000043960   ⟸   ENSCAFT00000068657
RefSeq Acc Id: ENSCAFP00000052052   ⟸   ENSCAFT00000092091
RefSeq Acc Id: ENSCAFP00000058615   ⟸   ENSCAFT00000061948
RefSeq Acc Id: XP_038350029   ⟸   XM_038494101
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038476211   ⟸   XM_038620283
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038541888   ⟸   XM_038685960
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038290679   ⟸   XM_038434751
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038412284   ⟸   XM_038556356
- Peptide Label: isoform X4

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000003510 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCAFP00000005230 UniProtKB/TrEMBL
  ENSCAFP00000038572 UniProtKB/TrEMBL
  ENSCAFP00000043960 UniProtKB/TrEMBL
  ENSCAFP00000052052 UniProtKB/TrEMBL
  ENSCAFP00000058615 UniProtKB/TrEMBL
  ENSCAFP00000059908 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000005646 UniProtKB/TrEMBL
  ENSCAFT00000045335 UniProtKB/TrEMBL
  ENSCAFT00000061948 UniProtKB/TrEMBL
  ENSCAFT00000068657 UniProtKB/TrEMBL
  ENSCAFT00000078719 UniProtKB/TrEMBL
  ENSCAFT00000092091 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
  3.10.200.10 UniProtKB/TrEMBL
  3.90.190.10 UniProtKB/TrEMBL
InterPro Alpha_CARP_receptor-type UniProtKB/TrEMBL
  CA_dom UniProtKB/TrEMBL
  CA_dom_sf UniProtKB/TrEMBL
  FN3_dom UniProtKB/TrEMBL
  FN3_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Prot-tyrosine_phosphatase-like UniProtKB/TrEMBL
  PTPase_domain UniProtKB/TrEMBL
  Tyr_Pase_AS UniProtKB/TrEMBL
  Tyr_Pase_cat UniProtKB/TrEMBL
  TYR_PHOSPHATASE_dom UniProtKB/TrEMBL
NCBI Gene PTPRZ1 ENTREZGENE
Pfam Carb_anhydrase UniProtKB/TrEMBL
  fn3 UniProtKB/TrEMBL
  Y_phosphatase UniProtKB/TrEMBL
PRINTS PRTYPHPHTASE UniProtKB/TrEMBL
PROSITE ALPHA_CA_2 UniProtKB/TrEMBL
  FN3 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_1 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_2 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_PTP UniProtKB/TrEMBL
SMART Carb_anhydrase UniProtKB/TrEMBL
  FN3 UniProtKB/TrEMBL
  PTPc UniProtKB/TrEMBL
  PTPc_motif UniProtKB/TrEMBL
Superfamily-SCOP SSF49265 UniProtKB/TrEMBL
  SSF51069 UniProtKB/TrEMBL
  SSF52799 UniProtKB/TrEMBL
UniProt A0A5F4BQA8_CANLF UniProtKB/TrEMBL
  A0A5F4CCI8_CANLF UniProtKB/TrEMBL
  A0A5F4CYQ1_CANLF UniProtKB/TrEMBL
  A0A5F4CZZ2_CANLF UniProtKB/TrEMBL
  F1PGN5_CANLF UniProtKB/TrEMBL
  J9NZ52_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:54793 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-16 PTPRZ1  protein tyrosine phosphatase receptor type Z1    protein tyrosine phosphatase, receptor type Z1  Symbol and/or name change 5135510 APPROVED