PTPRZ1 (protein tyrosine phosphatase receptor type Z1) - Rat Genome Database

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Gene: PTPRZ1 (protein tyrosine phosphatase receptor type Z1) Sus scrofa
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Symbol: PTPRZ1
Name: protein tyrosine phosphatase receptor type Z1
RGD ID: 13916068
Description: ENCODES a protein that exhibits fibroblast growth factor binding (ortholog); phosphatase activity (ortholog); protein tyrosine phosphatase activity (ortholog); INVOLVED IN axonal fasciculation (ortholog); axonogenesis (ortholog); brain development (ortholog); ASSOCIATED WITH amyotrophic lateral sclerosis (ortholog); Brain Injuries (ortholog); Helicobacter Infections (ortholog); FOUND IN axon (ortholog); cytoplasm (ortholog); dendrite (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: receptor-type tyrosine-protein phosphatase zeta
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1825,045,727 - 25,228,247 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11825,046,027 - 25,228,276 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21826,650,579 - 26,832,837 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

Genomics

Comparative Map Data
PTPRZ1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1825,045,727 - 25,228,247 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11825,046,027 - 25,228,276 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21826,650,579 - 26,832,837 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PTPRZ1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl7121,873,089 - 122,062,036 (+)EnsemblGRCh38hg38GRCh38
GRCh387121,873,161 - 122,062,036 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh377121,513,215 - 121,702,090 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367121,300,395 - 121,489,326 (+)NCBINCBI36hg18NCBI36
Build 347121,107,357 - 121,296,039NCBI
Celera7116,322,385 - 116,511,311 (+)NCBI
Cytogenetic Map7q31.32NCBI
HuRef7115,876,018 - 116,065,533 (+)NCBIHuRef
CHM1_17121,446,481 - 121,635,390 (+)NCBICHM1_1
CRA_TCAGchr7v27120,907,807 - 121,096,757 (+)NCBI
Ptprz1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39622,875,302 - 23,052,915 (+)NCBIGRCm39mm39
GRCm39 Ensembl622,875,501 - 23,052,915 (+)Ensembl
GRCm38622,875,315 - 23,052,916 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl622,875,502 - 23,052,916 (+)EnsemblGRCm38mm10GRCm38
MGSCv37622,825,502 - 23,002,916 (+)NCBIGRCm37mm9NCBIm37
MGSCv36622,825,503 - 23,002,917 (+)NCBImm8
Celera622,923,288 - 23,100,277 (+)NCBICelera
Cytogenetic Map6A3.1NCBI
Ptprz1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2451,397,316 - 51,595,220 (+)NCBI
Rnor_6.0 Ensembl449,941,304 - 50,140,762 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0449,941,046 - 50,140,764 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0449,730,302 - 49,927,328 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4449,267,521 - 49,468,692 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1449,498,094 - 49,699,266 (+)NCBI
Celera446,598,237 - 46,787,500 (+)NCBICelera
Cytogenetic Map4q22NCBI
Ptprz1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554793,624,993 - 3,733,183 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554793,611,658 - 3,734,225 (+)NCBIChiLan1.0ChiLan1.0
PTPRZ1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.17126,569,630 - 126,758,155 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7126,569,630 - 126,758,155 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v07113,882,557 - 114,073,283 (+)NCBIMhudiblu_PPA_v0panPan3
PTPRZ1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11459,769,553 - 59,944,111 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1459,827,650 - 59,943,315 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1459,203,408 - 59,361,617 (+)NCBI
ROS_Cfam_1.01459,825,102 - 59,979,392 (+)NCBI
UMICH_Zoey_3.11459,916,795 - 60,071,051 (+)NCBI
UNSW_CanFamBas_1.01459,543,462 - 59,698,673 (+)NCBI
UU_Cfam_GSD_1.01459,919,950 - 60,076,006 (+)NCBI
Ptprz1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511848,835,842 - 49,007,255 (+)NCBI
SpeTri2.0NW_0049366053,195,893 - 3,368,102 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PTPRZ1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12190,686,091 - 90,877,538 (+)NCBI
ChlSab1.1 Ensembl2190,686,167 - 90,877,649 (+)Ensembl
Ptprz1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462478313,911,525 - 14,105,403 (-)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 1 21
Low 10 2 1 2 2 2 1
Below cutoff 4 2 2 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000018088   ⟹   ENSSSCP00000017599
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1825,046,123 - 25,168,053 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000041168   ⟹   ENSSSCP00000035412
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1825,046,123 - 25,228,210 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000046236   ⟹   ENSSSCP00000058458
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1825,045,727 - 25,228,247 (-)Ensembl
RefSeq Acc Id: XM_003134735   ⟹   XP_003134783
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11825,046,027 - 25,228,274 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013985674   ⟹   XP_013841128
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11825,046,027 - 25,228,274 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013985675   ⟹   XP_013841129
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11825,046,027 - 25,228,276 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013985677   ⟹   XP_013841131
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11825,046,027 - 25,228,274 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003134783 (Get FASTA)   NCBI Sequence Viewer  
  XP_013841128 (Get FASTA)   NCBI Sequence Viewer  
  XP_013841129 (Get FASTA)   NCBI Sequence Viewer  
  XP_013841131 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_013841129   ⟸   XM_013985675
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_013841131   ⟸   XM_013985677
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_013841128   ⟸   XM_013985674
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_003134783   ⟸   XM_003134735
- Peptide Label: isoform X1
- UniProtKB: A0A286ZVC4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000035412   ⟸   ENSSSCT00000041168
RefSeq Acc Id: ENSSSCP00000058458   ⟸   ENSSSCT00000046236
RefSeq Acc Id: ENSSSCP00000017599   ⟸   ENSSSCT00000018088

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000016614 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000017599 UniProtKB/TrEMBL
  ENSSSCP00000035412 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000058458 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000018088 UniProtKB/TrEMBL
  ENSSSCT00000041168 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000046236 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
  3.10.200.10 UniProtKB/TrEMBL
  3.90.190.10 UniProtKB/TrEMBL
InterPro alpha_CARP_receptor-type UniProtKB/TrEMBL
  CA_dom UniProtKB/TrEMBL
  CA_dom_sf UniProtKB/TrEMBL
  FN3_dom UniProtKB/TrEMBL
  FN3_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Prot-tyrosine_phosphatase-like UniProtKB/TrEMBL
  PTPase_domain UniProtKB/TrEMBL
  Tyr_Pase_AS UniProtKB/TrEMBL
  Tyr_Pase_cat UniProtKB/TrEMBL
  TYR_PHOSPHATASE_dom UniProtKB/TrEMBL
KEGG Report ssc:100511294 UniProtKB/TrEMBL
NCBI Gene PTPRZ1 ENTREZGENE
Pfam Carb_anhydrase UniProtKB/TrEMBL
  fn3 UniProtKB/TrEMBL
  Y_phosphatase UniProtKB/TrEMBL
PRINTS PRTYPHPHTASE UniProtKB/TrEMBL
PROSITE ALPHA_CA_2 UniProtKB/TrEMBL
  FN3 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_1 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_2 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_PTP UniProtKB/TrEMBL
SMART Carb_anhydrase UniProtKB/TrEMBL
  FN3 UniProtKB/TrEMBL
  PTPc UniProtKB/TrEMBL
  PTPc_motif UniProtKB/TrEMBL
Superfamily-SCOP SSF49265 UniProtKB/TrEMBL
  SSF51069 UniProtKB/TrEMBL
  SSF52799 UniProtKB/TrEMBL
UniProt A0A286ZVC4 ENTREZGENE, UniProtKB/TrEMBL
  A0A287BQK7_PIG UniProtKB/TrEMBL
  F1SLX4_PIG UniProtKB/TrEMBL
VGNC ID VGNC:91996 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-02-19 PTPRZ1  protein tyrosine phosphatase receptor type Z1    protein tyrosine phosphatase, receptor type Z1  Symbol and/or name change 5135510 APPROVED