Ptprz1 (protein tyrosine phosphatase receptor type Z1) - Rat Genome Database

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Gene: Ptprz1 (protein tyrosine phosphatase receptor type Z1) Chinchilla lanigera
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Symbol: Ptprz1
Name: protein tyrosine phosphatase receptor type Z1
RGD ID: 9008992
Description: ENCODES a protein that exhibits fibroblast growth factor binding (ortholog); integrin binding (ortholog); phosphatase activity (ortholog); INVOLVED IN axonal fasciculation (ortholog); axonogenesis (ortholog); hematopoietic progenitor cell differentiation (ortholog); ASSOCIATED WITH amyotrophic lateral sclerosis (ortholog); Brain Hypoxia-Ischemia (ortholog); Brain Injuries (ortholog); FOUND IN axon (ortholog); dendrite (ortholog); dendritic spine (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: receptor-type tyrosine-protein phosphatase zeta
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554793,624,993 - 3,733,183 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554793,611,658 - 3,734,225 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Ptprz1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554793,624,993 - 3,733,183 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554793,611,658 - 3,734,225 (+)NCBIChiLan1.0ChiLan1.0
PTPRZ1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387121,873,161 - 122,062,036 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7121,873,089 - 122,062,036 (+)EnsemblGRCh38hg38GRCh38
GRCh377121,513,215 - 121,702,090 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367121,300,395 - 121,489,326 (+)NCBINCBI36Build 36hg18NCBI36
Build 347121,107,357 - 121,296,039NCBI
Celera7116,322,385 - 116,511,311 (+)NCBICelera
Cytogenetic Map7q31.32NCBI
HuRef7115,876,018 - 116,065,533 (+)NCBIHuRef
CHM1_17121,446,481 - 121,635,390 (+)NCBICHM1_1
T2T-CHM13v2.07123,189,006 - 123,377,936 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27120,907,807 - 121,096,757 (+)NCBI
Ptprz1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39622,875,302 - 23,052,915 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl622,875,501 - 23,052,915 (+)EnsemblGRCm39 Ensembl
GRCm38622,875,315 - 23,052,916 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl622,875,502 - 23,052,916 (+)EnsemblGRCm38mm10GRCm38
MGSCv37622,825,502 - 23,002,916 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36622,825,503 - 23,002,917 (+)NCBIMGSCv36mm8
Celera622,923,288 - 23,100,277 (+)NCBICelera
Cytogenetic Map6A3.1NCBI
cM Map69.92NCBI
Ptprz1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8452,363,006 - 52,560,905 (+)NCBIGRCr8
mRatBN7.2451,397,316 - 51,595,220 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl451,397,601 - 51,595,218 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx456,378,267 - 56,560,689 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0452,299,317 - 52,481,722 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0450,726,932 - 50,924,348 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0449,941,046 - 50,140,764 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl449,941,304 - 50,140,762 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0449,730,302 - 49,927,328 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4449,267,521 - 49,468,692 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1449,498,094 - 49,699,266 (+)NCBI
Celera446,598,237 - 46,787,500 (+)NCBICelera
Cytogenetic Map4q22NCBI
PTPRZ1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26158,743,511 - 158,934,195 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1710,753,753 - 10,944,449 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07113,882,557 - 114,073,283 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17126,569,630 - 126,758,155 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7126,569,630 - 126,758,155 (+)Ensemblpanpan1.1panPan2
PTPRZ1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11459,769,553 - 59,944,111 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1459,827,650 - 59,943,315 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1459,203,408 - 59,361,617 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01459,825,102 - 59,979,392 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1459,863,616 - 59,979,379 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11459,916,795 - 60,071,051 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01459,543,462 - 59,698,673 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01459,919,950 - 60,076,006 (+)NCBIUU_Cfam_GSD_1.0
Ptprz1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511848,835,842 - 49,007,255 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366053,196,548 - 3,368,175 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366053,195,893 - 3,368,102 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PTPRZ1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1825,045,742 - 25,168,053 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11825,046,027 - 25,228,276 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21826,650,579 - 26,832,837 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PTPRZ1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12190,686,091 - 90,877,538 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2190,686,167 - 90,877,649 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604212,666,623 - 12,858,179 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ptprz1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478313,912,332 - 14,105,292 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478313,911,525 - 14,105,403 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000011166   ⟹   ENSCLAP00000011031
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554793,624,993 - 3,733,183 (+)Ensembl
Ensembl Acc Id: ENSCLAT00000011167   ⟹   ENSCLAP00000011032
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554793,624,993 - 3,733,183 (+)Ensembl
RefSeq Acc Id: XM_013503257   ⟹   XP_013358711
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554793,611,658 - 3,734,225 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013358711 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000011031
  ENSCLAP00000011031.1
  ENSCLAP00000011032.1
RefSeq Acc Id: XP_013358711   ⟸   XM_013503257
- UniProtKB: A0A8C2VD99 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000011031   ⟸   ENSCLAT00000011166
Ensembl Acc Id: ENSCLAP00000011032   ⟸   ENSCLAT00000011167
Protein Domains
Alpha-carbonic anhydrase   Fibronectin type-III   Tyrosine specific protein phosphatases   Tyrosine-protein phosphatase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000007614 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000011166 ENTREZGENE
  ENSCLAT00000011166.1 UniProtKB/TrEMBL
  ENSCLAT00000011167.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
  3.10.200.10 UniProtKB/TrEMBL
  3.90.190.10 UniProtKB/TrEMBL
InterPro Alpha_CARP_receptor-type UniProtKB/TrEMBL
  CA_dom UniProtKB/TrEMBL
  CA_dom_sf UniProtKB/TrEMBL
  FN3_dom UniProtKB/TrEMBL
  FN3_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Prot-tyrosine_phosphatase-like UniProtKB/TrEMBL
  Protein-Tyr_Phosphatase UniProtKB/TrEMBL
  PTP_cat UniProtKB/TrEMBL
  Tyr_Pase_AS UniProtKB/TrEMBL
  Tyr_Pase_cat UniProtKB/TrEMBL
  Tyr_Pase_dom UniProtKB/TrEMBL
NCBI Gene Ptprz1 ENTREZGENE
PANTHER RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE UniProtKB/TrEMBL
  RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE ZETA UniProtKB/TrEMBL
Pfam Carb_anhydrase UniProtKB/TrEMBL
  fn3 UniProtKB/TrEMBL
  Y_phosphatase UniProtKB/TrEMBL
PRINTS PRTYPHPHTASE UniProtKB/TrEMBL
PROSITE ALPHA_CA_2 UniProtKB/TrEMBL
  FN3 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_1 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_2 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_PTP UniProtKB/TrEMBL
SMART Carb_anhydrase UniProtKB/TrEMBL
  FN3 UniProtKB/TrEMBL
  PTPc UniProtKB/TrEMBL
  PTPc_motif UniProtKB/TrEMBL
Superfamily-SCOP SSF49265 UniProtKB/TrEMBL
  SSF51069 UniProtKB/TrEMBL
  SSF52799 UniProtKB/TrEMBL
UniProt A0A8C2V7X8_CHILA UniProtKB/TrEMBL
  A0A8C2VD99 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-02-19 Ptprz1  protein tyrosine phosphatase receptor type Z1    protein tyrosine phosphatase, receptor type Z1  Symbol and/or name change 5135510 APPROVED
2016-08-03 Ptprz1  protein tyrosine phosphatase, receptor type Z1    protein tyrosine phosphatase, receptor-type, Z polypeptide 1  Symbol and/or name change 5135510 APPROVED