Ptprz1 (protein tyrosine phosphatase receptor type Z1) - Rat Genome Database

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Gene: Ptprz1 (protein tyrosine phosphatase receptor type Z1) Heterocephalus glaber
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Symbol: Ptprz1
Name: protein tyrosine phosphatase receptor type Z1
RGD ID: 18920731
Description: ENCODES a protein that exhibits fibroblast growth factor binding (ortholog); integrin binding (ortholog); phosphatase activity (ortholog); INVOLVED IN axonal fasciculation (ortholog); axonogenesis (ortholog); hematopoietic progenitor cell differentiation (ortholog); ASSOCIATED WITH amyotrophic lateral sclerosis (ortholog); Brain Hypoxia-Ischemia (ortholog); Brain Injuries (ortholog); FOUND IN axon (ortholog); dendrite (ortholog); dendritic spine (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: receptor-type tyrosine-protein phosphatase zeta
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478313,912,332 - 14,105,292 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478313,911,525 - 14,105,403 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Ptprz1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478313,912,332 - 14,105,292 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478313,911,525 - 14,105,403 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
PTPRZ1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387121,873,161 - 122,062,036 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7121,873,089 - 122,062,036 (+)EnsemblGRCh38hg38GRCh38
GRCh377121,513,215 - 121,702,090 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367121,300,395 - 121,489,326 (+)NCBINCBI36Build 36hg18NCBI36
Build 347121,107,357 - 121,296,039NCBI
Celera7116,322,385 - 116,511,311 (+)NCBICelera
Cytogenetic Map7q31.32NCBI
HuRef7115,876,018 - 116,065,533 (+)NCBIHuRef
CHM1_17121,446,481 - 121,635,390 (+)NCBICHM1_1
T2T-CHM13v2.07123,189,006 - 123,377,936 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27120,907,807 - 121,096,757 (+)NCBI
Ptprz1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39622,875,302 - 23,052,915 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl622,875,501 - 23,052,915 (+)EnsemblGRCm39 Ensembl
GRCm38622,875,315 - 23,052,916 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl622,875,502 - 23,052,916 (+)EnsemblGRCm38mm10GRCm38
MGSCv37622,825,502 - 23,002,916 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36622,825,503 - 23,002,917 (+)NCBIMGSCv36mm8
Celera622,923,288 - 23,100,277 (+)NCBICelera
Cytogenetic Map6A3.1NCBI
cM Map69.92NCBI
Ptprz1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8452,363,006 - 52,560,905 (+)NCBIGRCr8
mRatBN7.2451,397,316 - 51,595,220 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl451,397,601 - 51,595,218 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx456,378,267 - 56,560,689 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0452,299,317 - 52,481,722 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0450,726,932 - 50,924,348 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0449,941,046 - 50,140,764 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl449,941,304 - 50,140,762 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0449,730,302 - 49,927,328 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4449,267,521 - 49,468,692 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1449,498,094 - 49,699,266 (+)NCBI
Celera446,598,237 - 46,787,500 (+)NCBICelera
Cytogenetic Map4q22NCBI
Ptprz1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554793,624,993 - 3,733,183 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554793,611,658 - 3,734,225 (+)NCBIChiLan1.0ChiLan1.0
PTPRZ1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26158,743,511 - 158,934,195 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1710,753,753 - 10,944,449 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07113,882,557 - 114,073,283 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17126,569,630 - 126,758,155 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7126,569,630 - 126,758,155 (+)Ensemblpanpan1.1panPan2
PTPRZ1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11459,769,553 - 59,944,111 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1459,827,650 - 59,943,315 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1459,203,408 - 59,361,617 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01459,825,102 - 59,979,392 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1459,863,616 - 59,979,379 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11459,916,795 - 60,071,051 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01459,543,462 - 59,698,673 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01459,919,950 - 60,076,006 (+)NCBIUU_Cfam_GSD_1.0
Ptprz1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511848,835,842 - 49,007,255 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366053,196,548 - 3,368,175 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366053,195,893 - 3,368,102 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PTPRZ1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1825,045,742 - 25,168,053 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11825,046,027 - 25,228,276 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21826,650,579 - 26,832,837 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PTPRZ1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12190,686,091 - 90,877,538 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2190,686,167 - 90,877,649 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604212,666,623 - 12,858,179 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_004856447 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_004856448 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_004856449 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_004856450 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_004856451 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021237642 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01060209 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01060210 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01060211 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01060212 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01060213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01060214 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01060215 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01060216 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01060217 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01060218 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01060219 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01060220 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01060221 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GEBF01003728 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSHGLT00000010830   ⟹   ENSHGLP00000010708
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462478313,912,332 - 14,105,292 (-)Ensembl
RefSeq Acc Id: XM_004856447   ⟹   XP_004856504
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462478313,911,525 - 14,105,403 (-)NCBI
RefSeq Acc Id: XM_004856448   ⟹   XP_004856505
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462478313,911,525 - 14,105,403 (-)NCBI
RefSeq Acc Id: XM_004856449   ⟹   XP_004856506
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462478313,911,525 - 14,105,403 (-)NCBI
RefSeq Acc Id: XM_004856450   ⟹   XP_004856507
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462478313,911,525 - 14,105,403 (-)NCBI
RefSeq Acc Id: XM_004856451   ⟹   XP_004856508
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462478313,911,525 - 14,105,403 (-)NCBI
RefSeq Acc Id: XM_021237642   ⟹   XP_021093301
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462478313,911,525 - 14,105,403 (-)NCBI
RefSeq Acc Id: XP_021093301   ⟸   XM_021237642
- Peptide Label: isoform X4
- UniProtKB: A0A0P6JVS5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004856508   ⟸   XM_004856451
- Peptide Label: isoform X6
RefSeq Acc Id: XP_004856507   ⟸   XM_004856450
- Peptide Label: isoform X5
RefSeq Acc Id: XP_004856506   ⟸   XM_004856449
- Peptide Label: isoform X3
- UniProtKB: A0A0P6JVS5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004856505   ⟸   XM_004856448
- Peptide Label: isoform X2
- UniProtKB: A0A0P6JVS5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004856504   ⟸   XM_004856447
- Peptide Label: isoform X1
- UniProtKB: A0A0P6JVS5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000010708   ⟸   ENSHGLT00000010830


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000007675 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000010830 ENTREZGENE
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
  3.10.200.10 UniProtKB/TrEMBL
  3.90.190.10 UniProtKB/TrEMBL
InterPro Alpha_CARP_receptor-type UniProtKB/TrEMBL
  CA_dom UniProtKB/TrEMBL
  CA_dom_sf UniProtKB/TrEMBL
  FN3_dom UniProtKB/TrEMBL
  FN3_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Prot-tyrosine_phosphatase-like UniProtKB/TrEMBL
  Protein-Tyr_Phosphatase UniProtKB/TrEMBL
  PTPase_domain UniProtKB/TrEMBL
  Tyr_Pase_AS UniProtKB/TrEMBL
  Tyr_Pase_cat UniProtKB/TrEMBL
  TYR_PHOSPHATASE_dom UniProtKB/TrEMBL
NCBI Gene Ptprz1 ENTREZGENE
PANTHER RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE UniProtKB/TrEMBL
  RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE ZETA UniProtKB/TrEMBL
Pfam Carb_anhydrase UniProtKB/TrEMBL
  fn3 UniProtKB/TrEMBL
  Y_phosphatase UniProtKB/TrEMBL
PRINTS PRTYPHPHTASE UniProtKB/TrEMBL
PROSITE ALPHA_CA_2 UniProtKB/TrEMBL
  FN3 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_1 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_2 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_PTP UniProtKB/TrEMBL
SMART Carb_anhydrase UniProtKB/TrEMBL
  FN3 UniProtKB/TrEMBL
  PTPc UniProtKB/TrEMBL
  PTPc_motif UniProtKB/TrEMBL
Superfamily-SCOP SSF49265 UniProtKB/TrEMBL
  SSF51069 UniProtKB/TrEMBL
  SSF52799 UniProtKB/TrEMBL
UniProt A0A0P6JVS5 ENTREZGENE, UniProtKB/TrEMBL