Advanced Search (OLGA)

Gene: MECP2 (methyl-CpG binding protein 2) Canis lupus familiaris

Subscribe to Updates

Analyze

Symbol:

MECP2

Name:

methyl-CpG binding protein 2

RGD ID:

12154441

Description:

ENCODES a protein that exhibits chromatin binding (ortholog); chromatin DNA binding (ortholog); double-stranded methylated DNA binding (ortholog); INVOLVED IN cellular response to isoquinoline alkaloid (ortholog); cellular response to potassium ion (ortholog); cerebellum development (ortholog); PARTICIPATES IN DNA modification pathway; ASSOCIATED WITH adrenoleukodystrophy (ortholog); Angelman syndrome (ortholog); Animal Disease Models (ortholog); FOUND IN chromatin (ortholog); glutamatergic synapse (ortholog); protein-containing complex (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

methyl CpG binding protein 2 (Rett syndrome); methyl-CpG-binding protein 2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	121,866,721 - 121,876,088 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	121,873,218 - 121,932,994 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	107,201,895 - 107,204,829 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	X	125,014,436 - 125,017,609 (-)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	X	120,783,667 - 120,786,824 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	123,299,346 - 123,302,280 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	123,060,405 - 123,063,561 (-)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
MECP2	Dog	Binge Drinking		ISO	Mecp2 (Rattus norvegicus)	9068941	protein:decreased expression:hypothalamic microglia	RGD	PMID:30737481 and REF_RGD_ID:598092506
MECP2	Dog	Cocaine-Related Disorders	treatment	ISO	Mecp2 (Rattus norvegicus)	9068941		RGD	PMID:20711185 and REF_RGD_ID:12789445
MECP2	Dog	Experimental Seizures		ISO	Mecp2 (Rattus norvegicus)	9068941	mRNA:increased expression:dentate gyrus	RGD	PMID:12123686 and REF_RGD_ID:9587847
MECP2	Dog	fetal alcohol spectrum disorder	treatment	ISO	Mecp2 (Rattus norvegicus)	9068941		RGD	PMID:23763370 and REF_RGD_ID:13432044
MECP2	Dog	fetal alcohol spectrum disorder		ISO	Mecp2 (Rattus norvegicus)	9068941	mRNA:increased expression:pituitary gland (rat)	RGD	PMID:26509893 and REF_RGD_ID:11344152
MECP2	Dog	Fetal Growth Retardation		ISO	Mecp2 (Rattus norvegicus)	9068941	mRNA and protein:decreased expression:hippocampus:	RGD	PMID:16380407 and REF_RGD_ID:9588242
MECP2	Dog	gastrointestinal system disease	susceptibility	ISO	MECP2 (Homo sapiens)	9068941	associated with Rett Syndrome and DNA:mutations:multiple (human)	RGD	PMID:22331013 and REF_RGD_ID:12790976
MECP2	Dog	hepatocellular carcinoma		ISO	Mecp2 (Rattus norvegicus)	9068941	mRNA and protein:increased expression:liver	RGD	PMID:11844796 and REF_RGD_ID:2289670
MECP2	Dog	transient cerebral ischemia		ISO	Mecp2 (Rattus norvegicus)	9068941	mRNA:increased expression:hippocampus	RGD	PMID:12421618 and REF_RGD_ID:9587846
MECP2	Dog	X-Linked Intellectual Developmental Disorders		ISO	MECP2 (Homo sapiens)	9068941	DNA:missense mutations:cds:p.E137G and p.R167W (human)	RGD	PMID:11309367 and REF_RGD_ID:1601320

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
MECP2	Dog	adrenoleukodystrophy		ISO	MECP2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Adrenoleukodystrophy	ClinVar	PMID:10480214 more ...
MECP2	Dog	Angelman syndrome		ISO	MECP2 (Homo sapiens)	8554872	ClinVar more ...	ClinVar	PMID:10508514 more ...
MECP2	Dog	attention deficit hyperactivity disorder		ISO	MECP2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Attention deficit hyperactivity disorder	ClinVar	PMID:10767337 more ...
MECP2	Dog	autism spectrum disorder		ISO	MECP2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Autism spectrum disorder	ClinVar	PMID:25741868
MECP2	Dog	autistic disorder		ISO	MECP2 (Homo sapiens)	8554872	ClinVar more ...	ClinVar	PMID:10508514 more ...
MECP2	Dog	autistic disorder		ISO	MECP2 (Homo sapiens)	8554872	ClinVar more ...	ClinVar	PMID:10508514 more ...
MECP2	Dog	autistic disorder		ISO	MECP2 (Homo sapiens)	8554872	ClinVar more ...	ClinVar	PMID:10508514 more ...
MECP2	Dog	autistic disorder		ISO	MECP2 (Homo sapiens)	8554872	ClinVar more ...	ClinVar	PMID:10508514 more ...
MECP2	Dog	autistic disorder		ISO	MECP2 (Homo sapiens)	8554872	ClinVar more ...	ClinVar	PMID:10508514 more ...
MECP2	Dog	autosomal hemophilia A		ISO	MECP2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: AUTOSOMAL HEMOPHILIA A	ClinVar	PMID:31690835
MECP2	Dog	Barth syndrome		ISO	MECP2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: 3-Methylglutaconic aciduria type 2	ClinVar	PMID:10480214 more ...
MECP2	Dog	Cerebral Autosomal Recessive Arteriopathy with Subcortical Infarcts and Leukoencephalopathy		ISO	MECP2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: CARASIL	ClinVar	PMID:15737703 more ...
MECP2	Dog	cerebral creatine deficiency syndrome 1		ISO	MECP2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Creatine transporter deficiency	ClinVar	PMID:10480214 more ...
MECP2	Dog	Chromosome Xq28 Duplication Syndrome		ISO	MECP2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Chromosome Xq28 duplication syndrome	ClinVar
MECP2	Dog	developmental and epileptic encephalopathy 2		ISO	MECP2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Early infantile epileptic encephalopathy 2	ClinVar	PMID:25741868
MECP2	Dog	Developmental Disabilities		ISO	MECP2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Global developmental delay	ClinVar	PMID:10577905 more ...
MECP2	Dog	Developmental Disease		ISO	MECP2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Developmental disorder	ClinVar	PMID:25741868 and PMID:28492532
MECP2	Dog	dyskeratosis congenita		ISO	MECP2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Dyskeratosis congenita	ClinVar	PMID:10480214 more ...
MECP2	Dog	Emery-Dreifuss muscular dystrophy		ISO	MECP2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: X-linked Emery-Dreifuss muscular dystrophy	ClinVar	PMID:10480214 more ...
MECP2	Dog	epilepsy		ISO	MECP2 (Homo sapiens)	8554872	ClinVar more ...	ClinVar	PMID:10767337 more ...
MECP2	Dog	epilepsy		ISO	MECP2 (Homo sapiens)	8554872	ClinVar more ...	ClinVar	PMID:10767337 more ...
MECP2	Dog	Facial Hypertrichosis		ISO	MECP2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Facial hypertrichosis	ClinVar	PMID:32581362
MECP2	Dog	factor VIII deficiency		ISO	MECP2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Factor 8 deficiency and congenital	ClinVar	PMID:31690835
MECP2	Dog	favism		ISO	MECP2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Anemia more ...	ClinVar	PMID:10480214 more ...
MECP2	Dog	focal epilepsy		ISO	MECP2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Focal epilepsy	ClinVar	PMID:25741868 and PMID:34837432
MECP2	Dog	frontometaphyseal dysplasia		ISO	MECP2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Frontometaphyseal dysplasia	ClinVar	PMID:15689435 more ...
MECP2	Dog	generalized epilepsy		ISO	MECP2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Epileptic encephalopathy	ClinVar	PMID:25741868
MECP2	Dog	genetic disease		ISO	MECP2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Inborn genetic diseases	ClinVar	PMID:27929079 more ...
MECP2	Dog	genetic disease		ISO	MECP2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Inborn genetic diseases	ClinVar	PMID:10508514 more ...
MECP2	Dog	Hearing Loss		ISO	MECP2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Hearing impairment	ClinVar	PMID:11007980 more ...
MECP2	Dog	immunodeficiency 33		ISO	MECP2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Immunodeficiency 33	ClinVar	PMID:25741868
MECP2	Dog	intellectual disability		ISO	MECP2 (Homo sapiens)	8554872	ClinVar more ...	ClinVar	PMID:10508514 more ...
MECP2	Dog	intellectual disability		ISO	MECP2 (Homo sapiens)	8554872	ClinVar more ...	ClinVar	PMID:10508514 more ...
MECP2	Dog	intellectual disability		ISO	MECP2 (Homo sapiens)	8554872	ClinVar more ...	ClinVar	PMID:10508514 more ...
MECP2	Dog	intellectual disability		ISO	MECP2 (Homo sapiens)	8554872	ClinVar more ...	ClinVar	PMID:10508514 more ...
MECP2	Dog	intellectual disability		ISO	MECP2 (Homo sapiens)	8554872	ClinVar more ...	ClinVar	PMID:10508514 more ...
MECP2	Dog	Juberg Hayward Syndrome		ISO	MECP2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Cranio-oro-digital syndrome	ClinVar	PMID:15689435 more ...
MECP2	Dog	Melnick-Needles syndrome		ISO	MECP2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Osteodysplasty of Melnick and Needles	ClinVar	PMID:15689435 more ...
MECP2	Dog	methylmalonic acidemia and homocysteinemia cblX type		ISO	MECP2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: INTELLECTUAL DEVELOPMENTAL DISORDER and X-LINKED 3	ClinVar	PMID:15689435 more ...
MECP2	Dog	microcephaly		ISO	MECP2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Microcephaly	ClinVar	PMID:11007980 more ...
MECP2	Dog	Micrognathism		ISO	MECP2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Micrognathia	ClinVar	PMID:11007980 more ...
MECP2	Dog	Nervous System Malformations		ISO	MECP2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Abnormality of the nervous system	ClinVar	PMID:10508514 more ...
MECP2	Dog	Neurodevelopmental Disorders		ISO	MECP2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Neurodevelopmental disorder	ClinVar	PMID:10767337 more ...
MECP2	Dog	non-syndromic X-linked intellectual disability		ISO	MECP2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Non-syndromic X-linked intellectual disability	ClinVar	PMID:15351775 more ...
MECP2	Dog	otopalatodigital syndrome type 2		ISO	MECP2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Otopalatodigital Syndrome and Type II	ClinVar	PMID:15689435 more ...
MECP2	Dog	paraplegia		ISO	MECP2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Spastic paraplegia	ClinVar	PMID:10480214 more ...
MECP2	Dog	periventricular nodular heterotopia		ISO	MECP2 (Homo sapiens)	8554872	ClinVar more ...	ClinVar	PMID:10480214 more ...
MECP2	Dog	Periventricular Nodular Heterotopia 4		ISO	MECP2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: PERIVENTRICULAR NODULAR HETEROTOPIA 4	ClinVar	PMID:15689435 more ...
MECP2	Dog	Rett syndrome		ISO	MECP2 (Homo sapiens)	8554872	ClinVar more ...	ClinVar	PMID:10508514 more ...
MECP2	Dog	Rett syndrome		ISO	MECP2 (Homo sapiens)	8554872	ClinVar more ...	ClinVar	PMID:23262346 more ...
MECP2	Dog	Rett Syndrome, Atypical		ISO	MECP2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Atypical Rett syndrome	ClinVar	PMID:10508514 more ...
MECP2	Dog	Rett Syndrome, Zappella Variant		ISO	MECP2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Rett syndrome and zappella variant	ClinVar	PMID:10508514 more ...
MECP2	Dog	schizophrenia		ISO	MECP2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Schizophrenia	ClinVar	PMID:20479760 more ...
MECP2	Dog	severe congenital encephalopathy due to MECP2 mutation		ISO	MECP2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Severe neonatal-onset encephalopathy with microcephaly	ClinVar	PMID:23488948 more ...
MECP2	Dog	severe congenital encephalopathy due to MECP2 mutation		ISO	MECP2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Severe neonatal-onset encephalopathy with microcephaly	ClinVar	PMID:10232754 more ...
MECP2	Dog	severe congenital encephalopathy due to MECP2 mutation		ISO	MECP2 (Homo sapiens)	8554872	ClinVar more ...	ClinVar	PMID:10232754 more ...
MECP2	Dog	severe congenital encephalopathy due to MECP2 mutation		ISO	MECP2 (Homo sapiens)	8554872	ClinVar more ...	ClinVar	PMID:24511209 more ...
MECP2	Dog	Smith-Magenis syndrome		ISO	MECP2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Smith-Magenis Syndrome-like	ClinVar	PMID:10854091 more ...
MECP2	Dog	Splenomegaly		ISO	MECP2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Splenomegaly	ClinVar	PMID:25741868
MECP2	Dog	stereotypic movement disorder		ISO	MECP2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Stereotypic movement disorder	ClinVar	PMID:15737703 more ...
MECP2	Dog	syndromic X-linked intellectual disability Lubs type		ISO	MECP2 (Homo sapiens)	8554872	ClinVar more ...	ClinVar	PMID:10508514 more ...
MECP2	Dog	syndromic X-linked intellectual disability Lubs type		ISO	MECP2 (Homo sapiens)	8554872	ClinVar more ...	ClinVar	PMID:32105570 more ...
MECP2	Dog	X-linked intellectual disability-psychosis-macroorchidism syndrome		ISO	MECP2 (Homo sapiens)	8554872	ClinVar more ...	ClinVar	PMID:10232754 more ...
MECP2	Dog	X-linked intellectual disability-psychosis-macroorchidism syndrome		ISO	MECP2 (Homo sapiens)	8554872	ClinVar more ...	ClinVar	PMID:32472557 more ...

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
MECP2	Dog	Animal Disease Models		ISO	MECP2 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:28592917 and PMID:33010341
MECP2	Dog	anxiety disorder		ISO	MECP2 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:22231481
MECP2	Dog	Cocaine-Related Disorders		ISO	MECP2 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:20711185
MECP2	Dog	Craniofacial Abnormalities		ISO	MECP2 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:19559301
MECP2	Dog	hepatocellular carcinoma		ISO	MECP2 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:26189965
MECP2	Dog	Hyperalgesia		ISO	MECP2 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:33010341
MECP2	Dog	learning disability		ISO	MECP2 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:19921286
MECP2	Dog	Muscle Hypotonia		ISO	MECP2 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:19559301
MECP2	Dog	Myoclonus		ISO	MECP2 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:19559301
MECP2	Dog	pervasive developmental disorder		ISO	MECP2 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:22231481
MECP2	Dog	Psychomotor Disorders		ISO	MECP2 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:20098342
MECP2	Dog	pulmonary fibrosis		ISO	MECP2 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:21435439
MECP2	Dog	respiratory failure		ISO	MECP2 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:19559301

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
MECP2	Dog	autistic disorder		ISO	MECP2 (Homo sapiens)	7240710		OMIM
MECP2	Dog	Rett syndrome		ISO	MECP2 (Homo sapiens)	7240710		OMIM
MECP2	Dog	severe congenital encephalopathy due to MECP2 mutation		ISO	MECP2 (Homo sapiens)	7240710		OMIM
MECP2	Dog	syndromic X-linked intellectual disability Lubs type		ISO	MECP2 (Homo sapiens)	7240710		OMIM
MECP2	Dog	X-linked intellectual disability-psychosis-macroorchidism syndrome		ISO	MECP2 (Homo sapiens)	7240710		OMIM

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
MECP2	Dog	adult locomotory behavior	acts_upstream_of_or_within	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	associative learning	involved_in	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	behavioral fear response	acts_upstream_of_or_within	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	biogenic amine metabolic process	acts_upstream_of_or_within	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	brain development	acts_upstream_of_or_within	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	cardiolipin metabolic process	acts_upstream_of_or_within	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	catecholamine secretion	acts_upstream_of	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	cell population proliferation	acts_upstream_of	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	cellular response to isoquinoline alkaloid		ISO	Mecp2 (Rattus norvegicus)	9068941	bicuculline	RGD	PMID:22262897 and REF_RGD_ID:12790719
MECP2	Dog	cellular response to potassium ion		ISO	Mecp2 (Rattus norvegicus)	9068941		RGD	PMID:14593183 and REF_RGD_ID:12790707
MECP2	Dog	cerebellum development		ISO	Mecp2 (Rattus norvegicus)	9068941		RGD	PMID:14751287 and REF_RGD_ID:12743658
MECP2	Dog	cerebellum development	acts_upstream_of_or_within	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	cerebral cortex development		ISO	Mecp2 (Rattus norvegicus)	9068941		RGD	PMID:14751287 and REF_RGD_ID:12743658
MECP2	Dog	chemical synaptic transmission	acts_upstream_of_or_within	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	dendrite development	acts_upstream_of_or_within	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	epigenetic regulation of gene expression		ISO	Mecp2 (Rattus norvegicus)	9068941	DNA methylation	RGD	PMID:20735989 and REF_RGD_ID:9588647
MECP2	Dog	epigenetic regulation of gene expression	acts_upstream_of_or_within	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	excitatory postsynaptic potential	acts_upstream_of_or_within	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	gene expression	involved_in	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	genomic imprinting	acts_upstream_of_or_within	IEA	UniProtKB:P51608 more ...	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	glial cell proliferation	acts_upstream_of	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	glucocorticoid metabolic process	acts_upstream_of_or_within	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	glutamine metabolic process	acts_upstream_of_or_within	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	heterochromatin formation	acts_upstream_of_or_within	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	hippocampus development		ISO	Mecp2 (Rattus norvegicus)	9068941		RGD	PMID:14751287 and REF_RGD_ID:12743658
MECP2	Dog	inositol metabolic process	acts_upstream_of_or_within	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	learning	acts_upstream_of_or_within	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	long-term memory	acts_upstream_of_or_within	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	long-term synaptic potentiation	acts_upstream_of_or_within	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	lung alveolus development		ISO	Mecp2 (Rattus norvegicus)	9068941		RGD	PMID:21425435 and REF_RGD_ID:8552971
MECP2	Dog	memory	acts_upstream_of_or_within	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	multicellular organismal response to stress	acts_upstream_of_or_within	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	negative regulation of angiogenesis	involved_in	IEA	UniProtKB:P51608 and ensembl:ENSP00000395535	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	negative regulation of astrocyte differentiation		ISO	Mecp2 (Rattus norvegicus)	9068941		RGD	PMID:16881068 and REF_RGD_ID:9588644
MECP2	Dog	negative regulation of blood vessel endothelial cell migration	involved_in	IEA	UniProtKB:P51608 and ensembl:ENSP00000395535	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	negative regulation of dendrite extension		ISO	Mecp2 (Rattus norvegicus)	9068941		RGD	PMID:24636259 and REF_RGD_ID:12789709
MECP2	Dog	negative regulation of dendritic spine development		ISO	Mecp2 (Rattus norvegicus)	9068941		RGD	PMID:24636259 and REF_RGD_ID:12789709
MECP2	Dog	negative regulation of DNA-templated transcription		ISO	Mecp2 (Rattus norvegicus)	9068941		RGD	PMID:9038338 and REF_RGD_ID:1601325
MECP2	Dog	negative regulation of DNA-templated transcription	acts_upstream_of_or_within	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	negative regulation of DNA-templated transcription	involved_in	IEA	UniProtKB:P51608 and ensembl:ENSP00000395535	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	negative regulation of gene expression		ISO	Mecp2 (Rattus norvegicus)	9068941	Bdnf	RGD	PMID:19217433 and REF_RGD_ID:11069822
MECP2	Dog	negative regulation of gene expression	involved_in	IEA	UniProtKB:P51608 and ensembl:ENSP00000395535	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	negative regulation of gene expression via chromosomal CpG island methylation	involved_in	IEA	UniProtKB:P51608 and ensembl:ENSP00000395535	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	negative regulation of locomotion involved in locomotory behavior		ISO	Mecp2 (Rattus norvegicus)	9068941		RGD	PMID:27313794 and REF_RGD_ID:11568037
MECP2	Dog	negative regulation of neuron apoptotic process	acts_upstream_of_or_within	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	negative regulation of primary miRNA processing		ISO	Mecp2 (Rattus norvegicus)	9068941		RGD	PMID:24636259 and REF_RGD_ID:12789709
MECP2	Dog	negative regulation of protein binding		ISO	Mecp2 (Rattus norvegicus)	9068941		RGD	PMID:24636259 and REF_RGD_ID:12789709
MECP2	Dog	negative regulation of respiratory gaseous exchange		ISO	Mecp2 (Rattus norvegicus)	9068941		RGD	PMID:27313794 and REF_RGD_ID:11568037
MECP2	Dog	negative regulation of smooth muscle cell differentiation	involved_in	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	negative regulation of transcription by RNA polymerase II		ISO	Mecp2 (Rattus norvegicus)	9068941		RGD	PMID:24636259 more ...
MECP2	Dog	negative regulation of transcription by RNA polymerase II	acts_upstream_of_or_within	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	negative regulation of transcription by RNA polymerase II	involved_in	IEA	UniRule:UR000436755	150520179		UniProt	GO_REF:0000104
MECP2	Dog	negative regulation of transcription by RNA polymerase II	involved_in	IEA	InterPro:IPR017353	150520179		InterPro	GO_REF:0000002
MECP2	Dog	nervous system process involved in regulation of systemic arterial blood pressure	acts_upstream_of_or_within	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	neuromuscular process	acts_upstream_of_or_within	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	neuromuscular process controlling posture	acts_upstream_of_or_within	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	neuron differentiation		ISO	Mecp2 (Rattus norvegicus)	9068941		RGD	PMID:12605461 and REF_RGD_ID:12790706
MECP2	Dog	neuron differentiation	involved_in	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	neuron differentiation	acts_upstream_of_or_within	ISO	MGI:2158354	9068941	PMID:15345242	MGI	PMID:15345242
MECP2	Dog	neuron maturation	acts_upstream_of_or_within	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	neuron projection development	acts_upstream_of_or_within	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	Notch signaling pathway	involved_in	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	olfactory bulb development		ISO	Mecp2 (Rattus norvegicus)	9068941		RGD	PMID:12605461 and REF_RGD_ID:12790706
MECP2	Dog	oligodendrocyte development		ISO	Mecp2 (Rattus norvegicus)	9068941		RGD	PMID:26140854 and REF_RGD_ID:11343660
MECP2	Dog	oligodendrocyte differentiation		ISO	Mecp2 (Rattus norvegicus)	9068941		RGD	PMID:20697302 and REF_RGD_ID:12789708
MECP2	Dog	phosphatidylcholine metabolic process	acts_upstream_of_or_within	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	positive regulation of anterograde dense core granule transport		ISO	Mecp2 (Rattus norvegicus)	9068941		RGD	PMID:22127389 and REF_RGD_ID:12790715
MECP2	Dog	positive regulation of branching morphogenesis of a nerve		ISO	Mecp2 (Rattus norvegicus)	9068941		RGD	PMID:19442733 and REF_RGD_ID:11069248
MECP2	Dog	positive regulation of dendrite extension		ISO	Mecp2 (Rattus norvegicus)	9068941		RGD	PMID:19442733 and REF_RGD_ID:11069248
MECP2	Dog	positive regulation of dendritic spine development		ISO	Mecp2 (Rattus norvegicus)	9068941		RGD	PMID:24188180 and REF_RGD_ID:12789443
MECP2	Dog	positive regulation of DNA-templated transcription	acts_upstream_of_or_within	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	positive regulation of gene expression		ISO	Mecp2 (Rattus norvegicus)	9068941	Creb1 more ...	RGD	PMID:24636259 and REF_RGD_ID:12789709
MECP2	Dog	positive regulation of glial cell proliferation	acts_upstream_of_or_within	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	positive regulation of microtubule nucleation	involved_in	IEA	UniProtKB:P51608 and ensembl:ENSP00000395535	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	positive regulation of retrograde dense core granule transport		ISO	Mecp2 (Rattus norvegicus)	9068941		RGD	PMID:22127389 and REF_RGD_ID:12790715
MECP2	Dog	positive regulation of synaptic plasticity		ISO	Mecp2 (Rattus norvegicus)	9068941		RGD	PMID:23015442 and REF_RGD_ID:12790708
MECP2	Dog	positive regulation of transcription by RNA polymerase II	acts_upstream_of_or_within	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	post-embryonic development	acts_upstream_of_or_within	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	principal sensory nucleus of trigeminal nerve development		ISO	Mecp2 (Rattus norvegicus)	9068941		RGD	PMID:12605461 and REF_RGD_ID:12790706
MECP2	Dog	proprioception	acts_upstream_of_or_within	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	protein localization	acts_upstream_of_or_within	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	regulation of action potential firing threshold		ISO	Mecp2 (Rattus norvegicus)	9068941		RGD	PMID:27313794 and REF_RGD_ID:11568037
MECP2	Dog	regulation of gene expression	acts_upstream_of_or_within	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	regulation of respiratory gaseous exchange by nervous system process	acts_upstream_of_or_within	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	regulation of synapse organization	involved_in	ISO	Mecp2 (Rattus norvegicus)	9068941	PMID:19442733	SynGO	PMID:19442733 and REF_RGD_ID:11069248
MECP2	Dog	regulation of synaptic plasticity	acts_upstream_of_or_within	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	regulation of transcription by RNA polymerase II	acts_upstream_of_or_within	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	respiratory gaseous exchange by respiratory system	acts_upstream_of_or_within	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	response to alcohol		ISO	Mecp2 (Rattus norvegicus)	9068941		RGD	PMID:26509893 and REF_RGD_ID:11344152
MECP2	Dog	response to bisphenol A		ISO	Mecp2 (Rattus norvegicus)	9068941		RGD	PMID:22109888 and REF_RGD_ID:9588666
MECP2	Dog	response to cocaine		ISO	Mecp2 (Rattus norvegicus)	9068941		RGD	PMID:20711185 more ...
MECP2	Dog	response to estradiol		ISO	Mecp2 (Rattus norvegicus)	9068941		RGD	PMID:22109888 and REF_RGD_ID:9588666
MECP2	Dog	response to hypoxia	acts_upstream_of_or_within	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	response to ionizing radiation		ISO	Mecp2 (Rattus norvegicus)	9068941		RGD	PMID:17148264 and REF_RGD_ID:1601086
MECP2	Dog	response to lead ion		ISO	Mecp2 (Rattus norvegicus)	9068941		RGD	PMID:23246732 and REF_RGD_ID:9588316
MECP2	Dog	response to other organism	acts_upstream_of_or_within	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	sensory perception of pain	acts_upstream_of_or_within	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	social behavior		ISO	Mecp2 (Rattus norvegicus)	9068941		RGD	PMID:18614683 more ...
MECP2	Dog	social behavior	acts_upstream_of_or_within	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	spinal cord development		ISO	Mecp2 (Rattus norvegicus)	9068941	cervical spinal cord	RGD	PMID:12605461 and REF_RGD_ID:12790706
MECP2	Dog	startle response	acts_upstream_of_or_within	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	striatum development		ISO	Mecp2 (Rattus norvegicus)	9068941		RGD	PMID:12605461 and REF_RGD_ID:12790706
MECP2	Dog	synapse assembly	acts_upstream_of_or_within	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	thalamus development		ISO	Mecp2 (Rattus norvegicus)	9068941		RGD	PMID:12605461 and REF_RGD_ID:12790706
MECP2	Dog	trans-synaptic signaling by BDNF	acts_upstream_of	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	ventricular cardiac muscle tissue development		ISO	Mecp2 (Rattus norvegicus)	9068941		RGD	PMID:20735989 and REF_RGD_ID:9588647
MECP2	Dog	ventricular system development	acts_upstream_of_or_within	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	visual learning	acts_upstream_of_or_within	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
MECP2	Dog	centrosome	located_in	IEA	UniProtKB:P51608 and ensembl:ENSP00000395535	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	chromatin		ISO	Mecp2 (Rattus norvegicus)	9068941		RGD	PMID:9038338 and REF_RGD_ID:1601325
MECP2	Dog	cytoplasm	located_in	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	cytosol	located_in	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	glutamatergic synapse	is_active_in	ISO	Mecp2 (Rattus norvegicus)	9068941	PMID:19442733	SynGO	PMID:19442733 and REF_RGD_ID:11069248
MECP2	Dog	heterochromatin	located_in	IEA	UniProtKB:P51608 more ...	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	nucleoplasm	located_in	IEA	UniProtKB:A0A140VKC4 more ...	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	nucleus	located_in	IEA	UniRule:UR000436755	150520179		UniProt	GO_REF:0000104
MECP2	Dog	nucleus	located_in	IEA	UniProtKB:P51608 more ...	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	nucleus	located_in	IEA	UniProtKB-KW:KW-0539	150520179		UniProt	GO_REF:0000043
MECP2	Dog	nucleus	located_in	IEA	ARBA:ARBA00026330	150520179		UniProt	GO_REF:0000117
MECP2	Dog	nucleus	located_in	IEA	InterPro:IPR017353	150520179		InterPro	GO_REF:0000002
MECP2	Dog	nucleus	located_in	IEA	UniProtKB-SubCell:SL-0191	150520179		UniProt	GO_REF:0000044
MECP2	Dog	postsynapse	located_in	IEA	GO:0060079	150520179		GOC	GO_REF:0000108
MECP2	Dog	protein-containing complex		ISO	Mecp2 (Rattus norvegicus)	9068941		RGD	PMID:12473678 more ...
MECP2	Dog	synapse	located_in	IEA	GO:0007268 and GO:0099191	150520179		GOC	GO_REF:0000108

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
MECP2	Dog	chromatin binding		ISO	Mecp2 (Rattus norvegicus)	9068941		RGD	PMID:23688924 and REF_RGD_ID:9589062
MECP2	Dog	chromatin binding	enables	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	chromatin DNA binding		ISO	Mecp2 (Rattus norvegicus)	9068941		RGD	PMID:9038338 and REF_RGD_ID:1601325
MECP2	Dog	DNA binding	enables	IEA	ARBA:ARBA00029224	150520179		UniProt	GO_REF:0000117
MECP2	Dog	DNA binding	enables	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	DNA binding	enables	IEA	UniProtKB-KW:KW-0238	150520179		UniProt	GO_REF:0000043
MECP2	Dog	DNA binding	enables	IEA	InterPro:IPR001739 more ...	150520179		InterPro	GO_REF:0000002
MECP2	Dog	double-stranded methylated DNA binding		ISO	Mecp2 (Rattus norvegicus)	9068941		RGD	PMID:16314321 more ...
MECP2	Dog	double-stranded methylated DNA binding	enables	IEA	UniProtKB:P51608 more ...	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	double-stranded methylated DNA binding	enables	IEA	InterPro:IPR017353	150520179		InterPro	GO_REF:0000002
MECP2	Dog	double-stranded methylated DNA binding	enables	IEA	UniRule:UR000436755	150520179		UniProt	GO_REF:0000104
MECP2	Dog	enzyme binding		ISO	Dnmt1 (Rattus norvegicus)	9068941		RGD	PMID:12473678 and REF_RGD_ID:1359078
MECP2	Dog	four-way junction DNA binding		ISO	Mecp2 (Rattus norvegicus)	9068941		RGD	PMID:16314321 and REF_RGD_ID:1601323
MECP2	Dog	histone deacetylase binding		ISO	Hdac1 (Rattus norvegicus)	9068941		RGD	PMID:23671328 and REF_RGD_ID:9590112
MECP2	Dog	histone deacetylase binding		ISO	Hdac2 (Rattus norvegicus)	9068941		RGD	PMID:24441681 and REF_RGD_ID:9590255
MECP2	Dog	histone reader activity	enables	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	identical protein binding	enables	ISO	UniProtKB:Q00566	9068941	PMID:23335972	IntAct	PMID:23335972 and REF_RGD_ID:329955542
MECP2	Dog	methyl-CpG binding		ISO	Mecp2 (Rattus norvegicus)	9068941		RGD	PMID:12473678 and REF_RGD_ID:1359078
MECP2	Dog	methyl-CpG binding	enables	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	molecular adaptor activity	enables	ISO	MECP2 (Homo sapiens)	9068941	PMID:20405910	DisProt	PMID:20405910
MECP2	Dog	molecular condensate scaffold activity	enables	IEA	UniProtKB:P51608 and ensembl:ENSP00000395535	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	mRNA binding	enables	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	nucleic acid binding	enables	ISO	MECP2 (Homo sapiens)	9068941	PMID:20405910	DisProt	PMID:20405910
MECP2	Dog	promoter-specific chromatin binding		ISO	Mecp2 (Rattus norvegicus)	9068941		RGD	PMID:21425435 and REF_RGD_ID:8552971
MECP2	Dog	promoter-specific chromatin binding	enables	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	protein binding	enables	ISO	UniProtKB:Q8BHJ5 and UniProtKB:Q9QXE7	9068941	PMID:28348241	UniProt	PMID:28348241
MECP2	Dog	protein binding	enables	ISO	UniProtKB:O35846	9068941	PMID:15696166	IntAct	PMID:15696166
MECP2	Dog	protein binding	enables	ISO	PR:Q01147	9068941	PMID:18511691	MGI	PMID:18511691
MECP2	Dog	protein binding	enables	ISO	UniProtKB:Q60987	9068941	PMID:22357867	IntAct	PMID:22357867
MECP2	Dog	protein binding	enables	ISO	UniProtKB:O70494	9068941	PMID:20385708	IntAct	PMID:20385708
MECP2	Dog	protein binding	enables	ISO	PR:Q61687	9068941	PMID:17296936	MGI	PMID:17296936
MECP2	Dog	protein binding	enables	ISO	UniProtKB:Q61687 more ...	9068941	PMID:20159591	IntAct	PMID:20159591
MECP2	Dog	protein binding	enables	ISO	UniProtKB:Q3TKT4 and UniProtKB:Q60520	9068941	PMID:19602036	IntAct	PMID:19602036
MECP2	Dog	protein binding	enables	ISO	UniProtKB:Q15327	9068941	PMID:20599664	BHF-UCL	PMID:20599664
MECP2	Dog	protein binding	enables	ISO	UniProtKB:Q9WU42	9068941	PMID:23770565	UniProt	PMID:23770565
MECP2	Dog	protein binding	enables	ISO	UniProtKB:Q3TKT4 and UniProtKB:Q61687	9068941	PMID:24270455	IntAct	PMID:24270455
MECP2	Dog	protein binding	enables	ISO	UniProtKB:Q9Z2E1	9068941	PMID:23335972	IntAct	PMID:23335972 and REF_RGD_ID:329955542
MECP2	Dog	protein binding	enables	ISO	UniProtKB:O88895 and UniProtKB:Q60520	9068941	PMID:23770565	IntAct	PMID:23770565
MECP2	Dog	protein binding	enables	ISO	UniProtKB:Q60974 more ...	9068941	PMID:23770565	IntAct	PMID:23770565
MECP2	Dog	protein binding	enables	ISO	UniProtKB:O43196-2 more ...	9068941	PMID:32814053	IntAct	PMID:32814053
MECP2	Dog	protein binding	enables	ISO	UniProtKB:Q9H2X6 and UniProtKB:Q9QZR5	9068941	PMID:19820693	IntAct	PMID:19820693
MECP2	Dog	protein binding	enables	ISO	UniProtKB:P12755 and UniProtKB:Q60974	9068941	PMID:11441023	UniProt	PMID:11441023
MECP2	Dog	protein binding	enables	ISO	UniProtKB:O60907 and UniProtKB:Q9BZK7	9068941	PMID:28348241	DisProt	PMID:28348241
MECP2	Dog	protein binding	enables	ISO	UniProtKB:P61244	9068941	PMID:25609649	IntAct	PMID:25609649
MECP2	Dog	protein binding	enables	ISO	UniProtKB:P51531	9068941	PMID:15696166	IntAct	PMID:15696166
MECP2	Dog	protein binding	enables	ISO	UniProtKB:O75398	9068941	PMID:29636529	IntAct	PMID:29636529
MECP2	Dog	protein binding	enables	ISO	UniProtKB:Q9Z1T5	9068941	PMID:29636529	IntAct	PMID:29636529
MECP2	Dog	protein binding	enables	ISO	UniProtKB:Q61687	9068941	PMID:17296936	IntAct	PMID:17296936
MECP2	Dog	protein binding	enables	ISO	UniProtKB:P63165 and UniProtKB:Q9Y2M5	9068941	PMID:33961781	IntAct	PMID:33961781
MECP2	Dog	protein binding	enables	ISO	UniProtKB:P63165	9068941	PMID:37261502	IntAct	PMID:37261502
MECP2	Dog	protein binding	enables	ISO	UniProtKB:O88508	9068941	PMID:30102379	IntAct	PMID:30102379
MECP2	Dog	protein binding		ISO	Prpf3 (Rattus norvegicus)	9068941		RGD	PMID:21070191 and REF_RGD_ID:10045882
MECP2	Dog	protein binding	enables	ISO	UniProtKB:P46100	9068941	PMID:17296936	IntAct	PMID:17296936 and REF_RGD_ID:10047280
MECP2	Dog	protein binding		ISO	Nemf (Rattus norvegicus)	9068941		RGD	PMID:21070191 and REF_RGD_ID:10045882
MECP2	Dog	protein domain specific binding		ISO	Dgcr8 (Mus musculus)	9068941	RNA-binding domains	RGD	PMID:24636259 and REF_RGD_ID:12789709
MECP2	Dog	siRNA binding	enables	IEA	UniProtKB:Q9Z2D6 and ensembl:ENSMUSP00000098314	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	transcription corepressor activity	enables	IEA	UniProtKB:P51608 more ...	150520179		Ensembl	GO_REF:0000107
MECP2	Dog	unmethylated CpG binding		ISO	Mecp2 (Rattus norvegicus)	9068941		RGD	PMID:16314321 and REF_RGD_ID:1601323

RGD Manual Annotations

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
MECP2	Dog	DNA modification pathway		ISO	MECP2 (Homo sapiens)	9068941		RGD	PMID:23324617 and REF_RGD_ID:8695954

PMID:30032202

MECP2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	121,866,721 - 121,876,088 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	121,873,218 - 121,932,994 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	107,201,895 - 107,204,829 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	X	125,014,436 - 125,017,609 (-)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	X	120,783,667 - 120,786,824 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	123,299,346 - 123,302,280 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	123,060,405 - 123,063,561 (-)	NCBI		UU_Cfam_GSD_1.0

MECP2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	154,021,573 - 154,097,717 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	154,021,573 - 154,137,103 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	X	153,287,024 - 153,363,174 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	152,940,458 - 153,016,323 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	X	152,808,110 - 152,883,976	NCBI
Celera	X	153,520,969 - 153,596,868 (-)	NCBI		Celera
Cytogenetic Map	X	q28	NCBI
HuRef	X	141,928,231 - 142,007,659 (-)	NCBI		HuRef
CHM1_1	X	153,161,670 - 153,237,718 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	X	152,295,254 - 152,371,375 (-)	NCBI		T2T-CHM13v2.0

Mecp2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	73,070,198 - 73,129,296 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	73,070,198 - 73,129,296 (-)	Ensembl		GRCm39 Ensembl
GRCm38	X	74,026,592 - 74,085,690 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	74,026,592 - 74,135,363 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	X	71,272,160 - 71,330,975 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	X	70,279,550 - 70,338,313 (-)	NCBI		MGSCv36	mm8
Celera	X	65,279,211 - 65,338,021 (-)	NCBI		Celera
Cytogenetic Map	X	A7.3	NCBI
cM Map	X	37.63	NCBI

Mecp2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	156,932,481 - 156,995,981 (-)	NCBI		GRCr8
mRatBN7.2	X	151,781,177 - 151,844,687 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	151,789,930 - 151,844,689 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	153,931,091 - 153,985,757 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	157,494,308 - 157,548,973 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	155,166,123 - 155,220,783 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	156,650,389 - 156,713,813 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	156,655,960 - 156,705,233 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	152,390,961 - 152,461,647 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	159,980,599 - 160,035,260 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	X	160,055,071 - 160,104,134 (-)	NCBI
Celera	1	136,055,782 - 136,105,104 (+)	NCBI		Celera
Cytogenetic Map	X	q37	NCBI

Mecp2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955580	679,109 - 735,288 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955580	674,014 - 737,586 (-)	NCBI	ChiLan1.0	ChiLan1.0

MECP2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	154,061,838 - 154,137,177 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	154,065,444 - 154,140,771 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	143,571,864 - 143,647,192 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	153,458,248 - 153,527,854 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	153,465,204 - 153,527,854 (-)	Ensembl	panpan1.1		panPan2

Mecp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	119,165,167 - 119,228,780 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936809	911,764 - 966,839 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936809	902,938 - 967,771 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MECP2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	X	124,735,656 - 124,738,659 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	X	124,735,523 - 124,789,063 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	X	142,295,001 - 142,349,438 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MECP2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	128,445,028 - 128,519,892 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	X	128,453,577 - 128,455,785 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666065	66,318,831 - 66,395,535 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Mecp2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624946	628,284 - 685,246 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624946	620,581 - 685,339 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in MECP2
40 total Variants

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

adipose tissue	alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	reproductive system	respiratory system
6	5	5	23	22	16	6	6	6	6	33	22	12	14	10


RefSeq Transcripts	XM_022416327	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038451269	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038451270	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038464246	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038524738	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038524740	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038588701	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038588702	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038653221	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038653222	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000146	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000406	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000110	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000175	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000039	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCAFT00000030916 ⟹ ENSCAFP00000028750

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	X	121,873,218 - 121,932,994 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00000043990 ⟹ ENSCAFP00000039713

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	X	121,873,218 - 121,932,994 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00000065701 ⟹ ENSCAFP00000053080

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	X	121,874,120 - 121,932,994 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00000076107 ⟹ ENSCAFP00000050653

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	X	121,873,218 - 121,932,994 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00000077751 ⟹ ENSCAFP00000056846

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	X	121,873,218 - 121,924,603 (-)	Ensembl

RefSeq Acc Id:

XM_022416327 ⟹ XP_022272035

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	X	121,866,721 - 121,876,088 (-)	NCBI
Dog10K_Boxer_Tasha	X	107,201,895 - 107,204,829 (-)	NCBI

Sequence:

show sequence

GGAAGAAAAGTCAGAAGACCAGGATCTCCAGGGCCTCAAGGACAAACCCCTGAAATTTAAAAAGGTGAAGAAAGAGAAGAAAGAAGACAAAGAGGGCAAGCATGAGCCCCTGCAGCCACCGGCTCACC
ACTCTGCTGAACCAGCAGAGGCAGGCAAAGCGGAGACCTCAGAAGGGTCAGGCTCAGCCCCAGCTGTCCCGGAAGCTTCTGCCTCCCCCAAACAGCGACGCTCTATCATTCGTGACCGGGGACCCATG
TATGACGACCCCACTCTGCCTGAAGGTTGGACCCGAAAGCTTAAACAAAGGAAATCTGGCCGCTCCGCTGGGAAGTATGATGTGTATTTGATCAATCCCCAGGGAAAAGCCTTTCGCTCTAAAGTGGA
GTTGATTGCGTACTTCGAAAAGGTAGGCGACACCTCCCTGGACCCTAATGATTTTGACTTCACGGTAACTGGGAGAGGGAGCCCCTCCCGGCGAGAGCAGAAACCACCTAAGAAGCCCAAATCTCCCA
AAGCTCCAGGAACTGGCAGAGGTCGGGGACGCCCCAAAGGGAGCGGCACTGCGAGACCCAAGGCAGCAACATCAGAGGGTGTGCAGGTGAAAAGGGTCCTGGAGAAAAGTCCCGGGAAGCTGCTCGTC
AAGATGCCTTTTCAAGCTTCGCCCGGGAGCAAGGCTGAAGGGGGCGGGGCCACCACGTCAGCCCAGGTCATGGTTATCAAACGCCCAGGCCGGAAGCGAAAAGCCGAGGCTGACCCCCAGGCCATTCC
CAAGAAGCGGGGCCGAAAGCCAGGCAGTGTGGTGGCAGCTGCCGCCGCAGAGGCCAAAAAGAAAGCCGTGAAGGAGTCTTCCATCCGGTCCGTGCAGGAGACTGTGCTCCCCATCAAGAAGCGCAAGA
CTCGGGAGACGGTCAGCATTGAGGTGAAGGAGGTGGTGAAGCCCCTGCTGGTGTCCACCCTCGGCGAGAAGAGTGGAAAGGGACTGAAGACCTGCAAGAGCCCCGGACGGAAAAGCAAGGAGAGCAGC
CCGAAGGGGCGCAGCAGCAGCGCCTCCTCACCCCCCAAGAAGGAGCACCACCACCATCACCACCACTCAGAGCCCCCGAAGGCACCCGCGCCGCTGCTTCCGCCCCCGCCCCCTCCCCCACCTGAGCC
CCAGAGCTCCGAGGACCCCGCCAGCCCCCCTGAGCCCCAGGACTTGAGCAGCGGCGTCTGCAAAGAGGAGAAGATGGCGAGAGGAGGCTCGCTGGAGAGCGACGGCTGCCCCAAGGAGCCAGCTAAGA
CTCAGCCCACGGTCGCGACCGCCGCCACGGCCGCAGACAAGTACAAACACCGAGGGGAGGGAGAGCGCAAAGACATTGTTTCATCCTCCATGCCAAGGCCAAACAGAGAGGAGCCTGTGGACAGCCGG
ACGCCCGTGACCGAGAGAGTTAGCTGACTTTACACAGAGCGGATTGCAAAGCAAACCAACAAGAATAAAGGCAGCTGTTGTCTCTTCTCCTTATGGGTAGGGCTCTGACAAAGCTTCCCGATTAACTG
AAATAAAAAATATTTTTTTTTCTTTCAGTAAACTTAGAGTTTCGTGGCTTCAGGGTGGGAGTAGTTGGAGCATTGGGATGTTTTTCTTACCGACAAGCACAGTCAGGTTGAAGACCTAACCAGGGCCA
GAAGTAGCTTTGCACTTTTCTAAACTAGGCTCCTTCAACAAGGCTTGCTGCAGATACTACTGACCAGACAAGCTGTTGACCAGGCTTCTTAGGGTATGCCTGCACCTCCCCTCCCACCCAGACCTCCC
CCCACCCCCCATGTGCTCATTAGGGACAGAGAGTGGTTGAGAGGACACTCCCAGTCTCAGCTCTCCTCTCCTCCCGCCCTGCCCCACCCCCATCCCCCCAGCTCCTCCACCTTCCCCATCCCTACCCA
CATTGGGACAAGGAGGTGTGAGGCAGGAGAGACAGTTGGATTCTTTAGAGAAAAAGACAGAGATGGCCAGTGGCTACAGCCTGTGTGATCTCACCCATGGTGGCACAAATCTGGCCCCACGCCAGCCC
CAATCCAAAACTGACTAGGACATTTCACAGGACAGGGAAGTAGTACCTGTTCACTCCAGTTCTGGCATGGCTAGGAGGGAGTCAGTCCTTTGAGCTGCTGGGTGTAGACTGGCCTGAGCCAGAGGAGA
GGATGGCCGAGGGCCGTTCTCCAGTGGGTGGCGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGGCCGTGGAAGCAACGGGACAAGGCGTAGGCAGGCTGGCCCCGGGCTCCTGGGCTCCTCC
GGGTGGCACAGAGCAGTGGGGCTCATGGAATTCCTAGTTGCTCAGAGCAGTCTGTGACTGGTAGGTAGAGGCCTAGTGGACAGGTTGGGGGGCCAGGGGGAAGTAGGGGAAAATGTTCTTCCAAAACT
TTCCAATTCTACTCCTTTAGGGACAGCTTAGAACTATTTGCACTATTGAGTCTTCATGTTCCCACTTCAAAACAAACATGCTCTGAGAGCAAACTGGCTTGAATTGGTGACACTTTGTCCCTCAAGCC
ACCAGACATGACGGTGTTTAGAACTACCTGGATCTGTATATACCTGCGCTTGTTTTAAAGTGGGCTCAGCACATAGGGTTCCCACGAAGCTCCGAAACTCTAAGTGTTTGCTGCAATTTTATAAGGAC
TTCCTGATTGGTTTCTCTTCTGTCCTTCCATCTCTGCCTTCTTTCATCCATCCTTTCATTTCTTCCCCTCCTCGTTCATCCCTTCTGTACCAGGCACCCACAGTTCCAAGCTTTACCTGAGCTGATGC
TGGTCAGCTCAGGCCCCCAGATCTCACCCTGCCCTTGGCCTTCCCACTGCCAGCCCTAGCCCCGACCCAGCCCATTCTGAGGCCTGAGGAAAACCCGGGCTCTGCTGAGTCCACCTGGCCCTAGCACC
CTGGCCTCTCCGAAGGGCAAGAGAGCAGCAAGATCTTGCTCTCTGAGGGAGCTCCCTTCCCTGGTCAGACCCTGGATTCTGGGCCTTCTCGACCTTCTATCCAAGAAAAGCAAGCAGGAGAAGTTGGA
CAGATTTGGATTTGGAAGCTGAGGGTAGCACAGAGGCCCCCATGGCCTGCCATAGTCACCGAGTAGCCCAGCCCTGACCTTGACCTCGCCAGGCCCAGCCAGCATAGTGCAGTGCAATGGGGCGGCAG
GTGGGAAGAAATGCAGACGCCCCAGACCTGAGCTGGGACGGGCACCTAGACCCCTGGCCCCTCGGCTCCTCCTATAAGTTAACCATGAGTTCTTTTCTGATGGAAAATGCCTGGCTTTTGCTTGCTGG
AGACTGGGTGAGGCCAGCATATCACACATCTCCACATCTGTGCCAGGGGAATGGTGTGGGGGCCGAGAGGCTTGGGTTTGCTATGGGTGTTCATTGATCAATCTCCACTTAGGACCCCATCCTGTCAT
TCTGTGTTCAGGAAGTCCTTATCTAGCTGCATATCTTCATCATATTGGTATATCCTTTTCTGTGTTTACAGAGATGTCTCTTATATCTAAATCTGTCCAACTGAGAAGTACCTTATCAAAGTAGCAAA
TGAGACAGCAGTCTTATGCTTCCAGAAACACCCACAAGCACGTCCCATGCGAGCTGCTGCCATGAACTGTCAAGTGCGTGTTGTCTCGTGTATTTCAGTTATTGTCCCCTGGCTTCCTTATTGCGGTG
TAACCATGAAGGAGTGAAACATCCTAAAAACCGTCTAGCACTTCCTTGCCAGTCCTTAGTGATCAGGAACCATAGTTGACAGTTCCAATCAGTAGCTTAAGAAAAAAAAAAACGCGTTTGTCTCTTCC
GGAATGGTTAGAAGCAAGGGAGTTTGCCCCCATTCTGTTTGCAGAATCATAGTTGGCCTTTGTAGCATTTTTGTACCCATTTCCTTATGCTGCAAAAGCAAGTCCCACACCAGACCTGCTCTGCTGTT
GACCCTCTGGGCTTCACTGCTGACTCCTCCCCAGGAAAGGAAAGGGGGGTCGGAGGAGGGGGCGAGTCCTTCAGGACCCCTCTTCCTTCAAGGACAAAAGGCTCCTGACCCCAAAGTGGCCTGTCACT
CCTGGCACCCACAAAGGATGCCTAGCCACACGAGTACAGTGTCCGGCCAGTTTGCCATGGAGACACCGGCCGTTTTGGTCTGTTGGGTTTTTATCCATTACACTTAGCCCAATGGAATGTGACTCCCG
GAACCGGTGTCAAGAGCTGGCCTCTCCATAAGCTCAGTACCATCTGGTCCTGGGAAGAGGAGTGCAGGGCCCTCCATGCCCCCCTTTCACCTGTGACCATTCAGGGGCTGACCGGGCATTGGTGGTTG
AGCACATCATTTCAAGTGTCATTTTCTCTCGGCCTGTCCTGACCTGCAGCCCCTGAGGCTCCATAGGGTTTTCTCTCCTTACGCCCTTTCTTCCACATTCCCTCTTCTTCACCTAATAAAGGCATCAC
AAGTAAGTCACCATTAAGCAGGTCGCCTTGGTGGTTTGTTCCCCTGGCAGGCAGGGGCTCTGCAGCTGCCGTGCCACCCGTGTCCTGGGTCGGGTTGACAGGAGTTTGGAGTGAAAGCCAGGCAGTGG
GGTTCTCACCAGCTGTATCCAGCCCAGTTTGGGGGTGTGACCTCGATTTTGTGTGTACTTGAACATCACGAAGATGGCGGGCATCTTTTAGGGACTGTGTGAAGAATATAGAAATTGACCCACAGCTC
TCAGACACCTGTTCGCCTAGGTCACACAGTCCCTTTCAGTCTCTCCAGCCCTCGTTCTAGTTGGTAGTCACTACCTCCTCTCCCAACAGAATGCTGTATGTCCTCGAGCTCCTCTCACAATGCCCTGC
TCTGCCCTGCCCATTGGTGGGCCTGCCCTAACCAGTGCAGTTGCTGGCCTTGACATGGCAGTGAATCAGGGCACTAAGCCACAGCCAGGCTCTCAGACCGCTCCCTTCTGCTGCTGCTGCTGCATTCC
CGTGTCAGAAGGCACAGGCGACACCTAGAAATGCCCCGTTCCCCAGTCCATCAGTGCCAAACTACCCAAGGACCTCAGCCCCCTCCACTCCCTGGAAGGTGAAAGCCATGGTGGCGGCCCAGCAACAC
TGGCTACAGTCAGCACCTGGCTTCTACCCTTGAGGTCCCATGCAGGTGCGGGCAACACTGTTCAGGGGCACCATTCCAGGTGAGAGGCCACAGACTGTGGCACCAGCACCCAGAGCAGCCCCAAGTTG
TTCCCTGTCCCTCTGCCCAGCTTTTCATTGCTGTGATGGGGATCATGAAAGAAGGGACTAGCCTGAAACAAACTGCCATGTTTGATGGGGAAGGAGTTTCTTTAGCTGACAGGACCTCTGGATCTAAG
TAACTTAATAAGCAGCCGAAGCGCATGAGGGAGCAGAAGGTATGACGTGAACTCACCAGGTGGGGCCCACTGGATCTTGCAGAGCCGAAGTGGGGCCTGGCAGCCGAGCTCTGTGCCCCATTTCCAGA
GCATTTCCTTCCAGCTCTCTGGGCTGATGGAGCCAGGGAGGGTCACAGGTGCCGGTCTTGGAGAAGCCTTTTTCACCTCCTTTCCCAGCCAGTAGCCCCAAATTGTTGTTCCCTGATGGGAGTTTTAC
GCACAGATTTTAGGACTGATGGCCCGGACCTCAGGAAGCAAGCTGTGTCTAAGAGCCCTGTGGGCGTTTGCGTAGCCAGATCCCAGAGTCCGGGCTCATGGTGTTGGGGGCGGGGGGCAAGCATGGCA
GCGTCGCCCAGCCTGTGGTAGAGCCCCGCTCCCGTGCCCCTGTGGCCCCACCATGTCGCGTTCCTGCTCTTACTCTGTCCTCTGTAAGGGCCCCCACCTTTGCTCTCTTCATCAGTAAACTCGTCCAC
TCTGGAGGGGTTTGTTGAGTCTCCATTTTTGCGTCTTTGTCTTTTAGATACCGTATCAATCTTTAGAAAAGGCATAGTCTAATTGTTATATATAGCTAGGATACTGCCTCCCCCAGGGTCTCAAGTTA
CATATTAAAGAAGAAAAAAAGTGAACACTGAAACCCGTTCTCAACAATTCAGAAGGAAAACCTAGAAAACATTTGGCAGAAAATTACATTTCAATGTTTCTGAATGAATAAGAGCAAGCTTTTGCAAA
AATGCTGATCTAAAAATATTTGGAGTTTGGCCTGACATGTGGTGAGTGGTACAGGAAAAGGGGAATCCAGCCTGAAGCTGCTGGATCTGAGACTCGGGGCCATCCTAGCATTGGCGAGCCCCCTGTCC
TGTGGGGCCGCCTGCCTGGTCCCCAAGCTGTAGGAGCCCAGCGCTTGGTGTGGGAAGTAGCATCAACCAGTGGCTCCCAAGATCTGCGACGTTCTCACTACCCAGCACCACCTGTTTCTTGCTCCTTT
CACATCTCGACAGGACATTCCCCAAGTGCTGATTTTTTTTTTTTTTTCGGGAAAAAGGGAGTTCTAACTAGGGCCCAGGCAACTAGGAAGGTGAGGGTAAAGTCCCCCTTTTGGCCTTTGCCGGTCCC
CCGAGGACATCCCCTGCTCTGCTCTCCTAGGGGCCCAGGGCCTGGGTGAAGTGGTGCTCCCGTCTGCGCTCAGGGGTGAAGACAGAGGCCCGAGCACTCACTGTGGTGTGTGTCCCCCTCGCCCCTCA
CCAGCGAGAGCCCCTGGGCCAGAGGGAGGGCAGGCACAAGGAAGGGTGCTGGGCAGAACCGAGACCCTCACGAGGGGAAGCCCGGCCTTTGAGTCTGAGAGCATTAGGGAAACCTGCAAATTGCCTTT
GCTCCCCTAGCCCCCCCTCCTAGCTTACGTTTCCTCAGGTCCTCAGCAGCGAGAGACAATGAGATGAAAAGGCCAAGAGGTTTGGCTCCTGCTCACTGCTAGTCCCTCTCCTTTCAGTGTTTGTGTGT
CCAGTGACAAAGGTGTTCTTCCTGGTGACCCTGAGCATACCCAGTATCTTCTAGACTGTACGCGTAGGCCTGCTTGGTCTCCTCTCTCCTGGGCTTTGATTTTGCTTTTTAGCTTTGCTTTTAGTTTC
TCTGTCCCTTTTATTTAATGCACCAACTAGACACACAGAGCAGTTGAATTTTTATATATATATCTGTATATTGCACAATTATAAACTCATTTTGCTTGTGGCTCCACACACACACACAAAAGATCTGT
TAAAATTATACCTGTTGCTTAATTACAATATTTCTGATAACCATAGCATAGGACAAGGGAAAATAAAAAAACAAAAAAAAACAAAAACAAAAAAACACAAAAAAACAAAAAACAAAAAAAACTACAAA
CCTGTCTGCTGGTCACTTCTTCTGTCCAAGCAGATCCGTGGTCTTTCCTCGCTTCTCTCAAGGGCTTCCCTGTGCCAAGCGAAGGAGGCTCCAGACAGCATCCGGGTTTTGCACTGTTTCTCCCATGC
TTGTGAGAGAGGTCCCAGGATGCTGGTGCAAGACAGTTCACCTCAACGGGTGGGTTGAAGAGCGCTTCCTTGCCCTGGCAAAGTCTGGAATGTAGTTGGTACCACCTGGCCCCCTTCGACCTCTGGGT
GGGGCAGCTGGAGTCCACGGGGGAGGGGGATGGCCTGACCCCACCCCCAGCCCTCCCAGTGACCCAGTCACAGTGCTCATGTATGGAGAGTCAGCTCAGCAGGCCTCCCCACCAGTAGGGCTTCCACT
TGGCTGAGGCTGGAGGGCAGATGGGAGGCCTGTCACATCTCACATCTCAGAATGTGTGAGCTGCACAGGTAGACCCCAGGGACCCCAGAACCACATACAACAGTCCACTGGGTCCCCTCTAGGAGGTA
GCAAAGACTCCAGAAACCTCCCTTTCTCTCCTCCCCGTCCTACGAGTAACTGCATTTGCTTTTGTAATTCTTAATGAGCAATATCTGCTAGAGTTTAGCCGTAACAGTTCTTTTCGATCGTTTTTTTT
AAGTAATTAAAAAAAACACCAAAAAAAAAAAAAAACCCAGAAACTTGTTCTTCCAAAGCAGAGAG

hide sequence

RefSeq Acc Id:

XM_038451269 ⟹ XP_038307197

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	X	125,014,436 - 125,017,609 (-)	NCBI

RefSeq Acc Id:

XM_038451270 ⟹ XP_038307198

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	X	125,014,436 - 125,017,345 (-)	NCBI

RefSeq Acc Id:

XM_038464246 ⟹ XP_038320174

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	X	107,201,895 - 107,204,565 (-)	NCBI

RefSeq Acc Id:

XM_038524738 ⟹ XP_038380666

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	X	120,783,667 - 120,786,824 (-)	NCBI

RefSeq Acc Id:

XM_038524740 ⟹ XP_038380668

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	X	120,783,667 - 120,786,560 (-)	NCBI

RefSeq Acc Id:

XM_038588701 ⟹ XP_038444629

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	X	123,060,405 - 123,063,561 (-)	NCBI

RefSeq Acc Id:

XM_038588702 ⟹ XP_038444630

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	X	123,060,405 - 123,063,297 (-)	NCBI

RefSeq Acc Id:

XM_038653221 ⟹ XP_038509149

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	X	123,299,346 - 123,302,280 (-)	NCBI

RefSeq Acc Id:

XM_038653222 ⟹ XP_038509150

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	X	123,299,346 - 123,302,016 (-)	NCBI


Protein RefSeqs	XP_022272035	(Get FASTA)	NCBI Sequence Viewer
	XP_038307197	(Get FASTA)	NCBI Sequence Viewer
	XP_038307198	(Get FASTA)	NCBI Sequence Viewer
	XP_038320174	(Get FASTA)	NCBI Sequence Viewer
	XP_038380666	(Get FASTA)	NCBI Sequence Viewer
	XP_038380668	(Get FASTA)	NCBI Sequence Viewer
	XP_038444629	(Get FASTA)	NCBI Sequence Viewer
	XP_038444630	(Get FASTA)	NCBI Sequence Viewer
	XP_038509149	(Get FASTA)	NCBI Sequence Viewer
	XP_038509150	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000067667.1
	ENSCAFP00000070308.1
	ENSCAFP00000074161.1
	ENSCAFP00030019459.1
	ENSCAFP00030019473.1
	ENSCAFP00040033266.1
	ENSCAFP00040033295.1
	ENSCAFP00040033313.1
	ENSCAFP00040033354.1

RefSeq Acc Id:

XP_022272035 ⟸ XM_022416327

- Peptide Label:

isoform X1

- Sequence:

show sequence

MYDDPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDFDFTVTGRGSPSRREQKPPKKPKSPKAPGTGRGRGRPKGSGTARPKAATSEGVQVKRVLEKSPGKLL
VKMPFQASPGSKAEGGGATTSAQVMVIKRPGRKRKAEADPQAIPKKRGRKPGSVVAAAAAEAKKKAVKESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLVSTLGEKSGKGLKTCKSPGRKSKES
SPKGRSSSASSPPKKEHHHHHHHSEPPKAPAPLLPPPPPPPPEPQSSEDPASPPEPQDLSSGVCKEEKMARGGSLESDGCPKEPAKTQPTVATAATAADKYKHRGEGERKDIVSSSMPRPNREEPVDS
RTPVTERVS

hide sequence

Ensembl Acc Id:

ENSCAFP00000028750 ⟸ ENSCAFT00000030916

Ensembl Acc Id:

ENSCAFP00000039713 ⟸ ENSCAFT00000043990

Ensembl Acc Id:

ENSCAFP00000056846 ⟸ ENSCAFT00000077751

Ensembl Acc Id:

ENSCAFP00000050653 ⟸ ENSCAFT00000076107

Protein Domains

MBD

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000019440	Ensembl
	ENSCAFG00000058487	UniProtKB/TrEMBL
	ENSCAFG00030012057	UniProtKB/TrEMBL
	ENSCAFG00040020624	UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000094941.1	UniProtKB/TrEMBL
	ENSCAFT00000100298.1	UniProtKB/TrEMBL
	ENSCAFT00000107129.1	UniProtKB/TrEMBL
	ENSCAFT00030022306.1	UniProtKB/TrEMBL
	ENSCAFT00030022325.1	UniProtKB/TrEMBL
	ENSCAFT00040038159.1	UniProtKB/TrEMBL
	ENSCAFT00040038190.1	UniProtKB/TrEMBL
	ENSCAFT00040038208.1	UniProtKB/TrEMBL
	ENSCAFT00040038250.1	UniProtKB/TrEMBL
Gene3D-CATH	Methyl-cpg-binding Protein 2, Chain A	UniProtKB/TrEMBL
InterPro	DNA-bd_dom_sf	UniProtKB/TrEMBL
	Me_CpG-bd_MeCP2	UniProtKB/TrEMBL
	MeCP2/MBD4	UniProtKB/TrEMBL
	Methyl_CpG_DNA-bd	UniProtKB/TrEMBL
NCBI Gene	MECP2	ENTREZGENE
PANTHER	METHYL-CPG-BINDING PROTEIN	UniProtKB/TrEMBL
	METHYL-CPG-BINDING PROTEIN 2	UniProtKB/TrEMBL
Pfam	MBD	UniProtKB/TrEMBL
PIRSF	Methyl_CpG_bd_MeCP2	UniProtKB/TrEMBL
PROSITE	MBD	UniProtKB/TrEMBL
SMART	MBD	UniProtKB/TrEMBL
Superfamily-SCOP	DNA-binding domain	UniProtKB/TrEMBL
UniProt	A0A8C0N4P8_CANLF	UniProtKB/TrEMBL
	A0A8C0NDX4_CANLF	UniProtKB/TrEMBL
	A0A8C0TAF5_CANLF	UniProtKB/TrEMBL
	A0A8C0TBH1_CANLF	UniProtKB/TrEMBL
	A0A8C0TE44_CANLF	UniProtKB/TrEMBL
VGNC ID	VGNC:43115	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
		Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations