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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:bivalirudin pharmacodynamics pathway
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Accession:PW:0002149 term browser browse the term
Definition:The pathway of bivalirudin-target interaction and of the biochemical or physiological responses to drug. The drug is a bivalent direct thrombin inhibitor. Genetic variations can cause differences in the response of the organism to the drug.
Synonyms:related_synonym: SMP:00277


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bivalirudin pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO SMPDB SMP:00277 NCBI chr12:26,379,087...26,397,180
Ensembl chr12:26,379,090...26,397,004 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00277 NCBI chr11:78,521,760...78,538,256
Ensembl chr11:78,521,598...78,538,258 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00277 NCBI chr17:9,045,990...9,073,552
Ensembl chr17:9,046,002...9,073,520 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00277 NCBI chr 2:80,527,451...80,544,835
Ensembl chr 2:80,527,446...80,544,828 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO SMPDB SMP:00277 NCBI chr 7:3,751,290...3,900,797
Ensembl chr 7:3,751,292...3,900,762 		JBrowse link
G F13B coagulation factor XIII B chain ISO SMPDB SMP:00277
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00277 NCBI chr 2:15,793,257...15,819,151
Ensembl chr 2:15,791,455...15,819,137 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00277 NCBI chr 4:122,827,018...122,837,673
Ensembl chr 4:122,826,644...122,837,666 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00277 NCBI chr 4:81,403,273...81,484,908
Ensembl chr 4:81,403,274...81,485,066 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00277 NCBI chr11:78,512,389...78,518,668
Ensembl chr11:78,512,137...78,518,668 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00277 NCBI chr  X:125,265,330...125,350,853
Ensembl chr  X:125,229,450...125,350,853 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00277 NCBI chr  X:114,218,704...114,250,436
Ensembl chr  X:114,218,707...114,250,429 		JBrowse link
G FGA fibrinogen alpha chain ISO SMPDB SMP:00277 NCBI chr 8:74,574,870...74,584,202
Ensembl chr 8:74,574,882...74,584,202 		JBrowse link
G FGB fibrinogen beta chain ISO SMPDB SMP:00277 NCBI chr 8:74,598,170...74,607,409
Ensembl chr 8:74,595,688...74,607,409 		JBrowse link
G FGG fibrinogen gamma chain ISO SMPDB SMP:00277 NCBI chr 8:74,553,040...74,562,151
Ensembl chr 8:74,553,105...74,563,688 		JBrowse link
G GGCX gamma-glutamyl carboxylase ISO SMPDB SMP:00277 NCBI chr 3:59,202,363...59,219,807
Ensembl chr 3:59,202,429...59,218,145 		JBrowse link
G KLKB1 kallikrein B1 ISO SMPDB SMP:00277 NCBI chr15:47,071,581...47,100,272
Ensembl chr15:47,071,556...47,103,622 		JBrowse link
G PLAT plasminogen activator, tissue type ISO SMPDB SMP:00277 NCBI chr17:11,195,599...11,223,821
Ensembl chr17:11,195,602...11,224,032 		JBrowse link
G PLG plasminogen ISO SMPDB SMP:00277 NCBI chr 1:7,062,399...7,109,521
Ensembl chr 1:7,061,192...7,110,555 		JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00277 NCBI chr 3:17,386,230...17,389,162
Ensembl chr 3:17,386,245...17,389,905 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 4040
    drug pathway 384
      blood and blood forming organs drug pathway 57
        antithrombotic drug pathway 57
          anticoagulant drug pathway 25
            direct thrombin inhibitor drug pathway 20
              bivalirudin drug pathway 20
                bivalirudin pharmacodynamics pathway 20
paths to the root