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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:vasopressin signaling pathway
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Accession:PW:0000491 term browser browse the term
Definition:The hormone vasopressin plays central roles in cardiovascular and water homeostasis by signaling via two receptor types, G-protein coupled receptors coupling to particular G alpha subunits of heterotrimeric G proteins.
Synonyms:related_synonym: Avp signaling pathway;   arginine-vasopressin signaling pathway
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vasopressin signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy6 adenylate cyclase 6 ISO RGD PMID:15579502 PMID:18431594 PMID:18971210 RGD:2312654 RGD:2312656 RGD:2313211 NCBI chrNW_004624816:3,366,594...3,387,431
Ensembl chrNW_004624816:3,366,744...3,387,447 		JBrowse link
G Akap7 A-kinase anchoring protein 7 ISO RGD PMID:15037626 PMID:18431594 RGD:1303982 RGD:2312656 NCBI chrNW_004624753:5,297,268...5,436,631
Ensembl chrNW_004624753:5,303,234...5,436,636 		JBrowse link
G Aqp2 aquaporin 2 ISO RGD PMID:15037626 PMID:15579502 PMID:18431594 PMID:18971210 RGD:1303982 RGD:2312654 RGD:2312656 RGD:2313211 NCBI chrNW_004624816:2,332,477...2,340,797
Ensembl chrNW_004624816:2,335,471...2,340,828 		JBrowse link
G Avp arginine vasopressin ISO RGD PMID:12942143 PMID:14624682 PMID:18299204 PMID:18431594 RGD:1358326 RGD:1579891 RGD:2301920 RGD:2312656 NCBI chrNW_004624741:4,208,305...4,210,097
Ensembl chrNW_004624741:4,208,329...4,210,071 		JBrowse link
G Avpr1a arginine vasopressin receptor 1A ISO RGD PMID:12942143 PMID:14624682 RGD:1358326 RGD:1579891 NCBI chrNW_004624802:4,893,172...4,900,177
Ensembl chrNW_004624802:4,894,235...4,900,276 		JBrowse link
G Avpr1b arginine vasopressin receptor 1B ISO RGD PMID:7624319 PMID:14624682 PMID:19047484 RGD:1579891 RGD:2312649 RGD:61542 NCBI chrNW_004624807:5,237,036...5,247,383
Ensembl chrNW_004624807:5,237,036...5,241,845 		JBrowse link
G Avpr2 arginine vasopressin receptor 2 ISO RGD PMID:11882591 PMID:14624682 PMID:18431594 PMID:18971210 RGD:1579891 RGD:2312654 RGD:2312656 RGD:628560 NCBI chrNW_004624946:541,317...543,397
Ensembl chrNW_004624946:541,362...543,492 		JBrowse link
G Gna11 G protein subunit alpha 11 ISO RGD PMID:14624682 RGD:1579891 NCBI chrNW_004624828:6,078,485...6,093,744
Ensembl chrNW_004624828:6,077,851...6,093,750 		JBrowse link
G Gnaq G protein subunit alpha q ISO RGD PMID:14624682 RGD:1579891 NCBI chrNW_004624811:5,158,665...5,485,812
Ensembl chrNW_004624811:5,163,793...5,486,140 		JBrowse link
G Gnas GNAS complex locus ISO RGD PMID:14624682 PMID:15579502 PMID:18431594 PMID:18971210 RGD:1579891 RGD:2312654 RGD:2312656 RGD:2313211 NCBI chrNW_004624741:25,138,678...25,197,194
Ensembl chrNW_004624741:25,183,329...25,196,880 		JBrowse link
G Myo5b myosin VB ISO RGD PMID:17156409 PMID:18431594 RGD:2312655 RGD:2312656 NCBI chrNW_004624778:13,352,285...13,740,621
Ensembl chrNW_004624778:13,347,705...13,740,767 		JBrowse link
G Rab11a RAB11A, member RAS oncogene family ISO RGD PMID:17156409 PMID:18431594 RGD:2312655 RGD:2312656 NCBI chrNW_004624781:6,699,926...6,718,020
Ensembl chrNW_004624781:6,699,926...6,718,545 		JBrowse link
G Rab11fip2 RAB11 family interacting protein 2 ISO RGD PMID:17156409 PMID:18431594 RGD:2312655 RGD:2312656 NCBI chrNW_004624737:28,633,815...28,675,773
Ensembl chrNW_004624737:28,634,079...28,686,886 		JBrowse link
G Sipa1 signal-induced proliferation-associated 1 ISO RGD PMID:18431594 RGD:2312656 NCBI chrNW_004624767:20,745,125...20,757,243
Ensembl chrNW_004624767:20,745,168...20,757,219 		JBrowse link
G Snap23 synaptosome associated protein 23 ISO RGD PMID:18431594 RGD:2312656 NCBI chrNW_004624804:9,609,777...9,643,670
Ensembl chrNW_004624804:9,610,308...9,641,933 		JBrowse link
G Vamp2 vesicle associated membrane protein 2 ISO RGD PMID:18431594 RGD:2312656 NCBI chrNW_004624786:10,723,791...10,727,654
Ensembl chrNW_004624786:10,724,964...10,727,649 		JBrowse link
vasopressin signaling pathway via receptor type 1 term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Avp arginine vasopressin ISO RGD PMID:14624682 RGD:1579891 NCBI chrNW_004624741:4,208,305...4,210,097
Ensembl chrNW_004624741:4,208,329...4,210,071 		JBrowse link
G Avpr1a arginine vasopressin receptor 1A ISO RGD PMID:14624682 RGD:1579891 NCBI chrNW_004624802:4,893,172...4,900,177
Ensembl chrNW_004624802:4,894,235...4,900,276 		JBrowse link
G Avpr1b arginine vasopressin receptor 1B ISO RGD PMID:14624682 RGD:1579891 NCBI chrNW_004624807:5,237,036...5,247,383
Ensembl chrNW_004624807:5,237,036...5,241,845 		JBrowse link
G Gna11 G protein subunit alpha 11 ISO RGD PMID:14624682 RGD:1579891 NCBI chrNW_004624828:6,078,485...6,093,744
Ensembl chrNW_004624828:6,077,851...6,093,750 		JBrowse link
G Gnaq G protein subunit alpha q ISO RGD PMID:14624682 RGD:1579891 NCBI chrNW_004624811:5,158,665...5,485,812
Ensembl chrNW_004624811:5,163,793...5,486,140 		JBrowse link
vasopressin signaling pathway via receptor type 2 term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy2 adenylate cyclase 2 ISO SMPDB SMP:00322 NCBI chrNW_004624751:5,004,186...5,409,891
Ensembl chrNW_004624751:5,004,263...5,413,994 		JBrowse link
G Adcy6 adenylate cyclase 6 ISO RGD PMID:15579502 PMID:18431594 PMID:18971210 RGD:2312654 RGD:2312656 RGD:2313211 NCBI chrNW_004624816:3,366,594...3,387,431
Ensembl chrNW_004624816:3,366,744...3,387,447 		JBrowse link
G Akap7 A-kinase anchoring protein 7 ISO RGD PMID:15037626 PMID:18431594 RGD:1303982 RGD:2312656 NCBI chrNW_004624753:5,297,268...5,436,631
Ensembl chrNW_004624753:5,303,234...5,436,636 		JBrowse link
G Aqp2 aquaporin 2 ISO RGD PMID:15037626 PMID:15579502 PMID:18431594 PMID:18971210 RGD:1303982 RGD:2312654 RGD:2312656 RGD:2313211 NCBI chrNW_004624816:2,332,477...2,340,797
Ensembl chrNW_004624816:2,335,471...2,340,828 		JBrowse link
G Avp arginine vasopressin ISO RGD PMID:14624682 PMID:18431594 RGD:1579891 RGD:2312656 NCBI chrNW_004624741:4,208,305...4,210,097
Ensembl chrNW_004624741:4,208,329...4,210,071 		JBrowse link
G Avpr2 arginine vasopressin receptor 2 ISO RGD
SMPDB		 PMID:14624682 PMID:18431594 PMID:18971210 RGD:1579891 RGD:2312654 RGD:2312656 SMP:00322 NCBI chrNW_004624946:541,317...543,397
Ensembl chrNW_004624946:541,362...543,492 		JBrowse link
G Fshr follicle stimulating hormone receptor ISO SMPDB SMP:00322 NCBI chrNW_004624738:30,170,514...30,369,250
Ensembl chrNW_004624738:30,176,817...30,369,166 		JBrowse link
G Gnas GNAS complex locus ISO RGD
SMPDB		 PMID:14624682 PMID:15579502 PMID:18431594 PMID:18971210 RGD:1579891 RGD:2312654 RGD:2312656 RGD:2313211 SMP:00322 NCBI chrNW_004624741:25,138,678...25,197,194
Ensembl chrNW_004624741:25,183,329...25,196,880 		JBrowse link
G Gnb1 G protein subunit beta 1 ISO SMPDB SMP:00322 NCBI chrNW_004624818:7,937,061...8,002,798
Ensembl chrNW_004624818:7,936,932...8,003,433 		JBrowse link
G Gng12 G protein subunit gamma 12 ISO SMPDB SMP:00322 NCBI chrNW_004624742:27,652,114...27,721,668
Ensembl chrNW_004624742:27,700,538...27,718,555 		JBrowse link
G Myo5b myosin VB ISO RGD PMID:18431594 RGD:2312656 NCBI chrNW_004624778:13,352,285...13,740,621
Ensembl chrNW_004624778:13,347,705...13,740,767 		JBrowse link
G Prkacb protein kinase cAMP-activated catalytic subunit beta ISO SMPDB SMP:00322 NCBI chrNW_004624742:13,243,248...13,357,873
Ensembl chrNW_004624742:13,242,593...13,357,986 		JBrowse link
G Rab11a RAB11A, member RAS oncogene family ISO RGD PMID:18431594 RGD:2312656 NCBI chrNW_004624781:6,699,926...6,718,020
Ensembl chrNW_004624781:6,699,926...6,718,545 		JBrowse link
G Rab11fip2 RAB11 family interacting protein 2 ISO RGD PMID:18431594 RGD:2312656 NCBI chrNW_004624737:28,633,815...28,675,773
Ensembl chrNW_004624737:28,634,079...28,686,886 		JBrowse link
G Sipa1 signal-induced proliferation-associated 1 ISO RGD PMID:18431594 RGD:2312656 NCBI chrNW_004624767:20,745,125...20,757,243
Ensembl chrNW_004624767:20,745,168...20,757,219 		JBrowse link
G Snap23 synaptosome associated protein 23 ISO RGD PMID:18431594 RGD:2312656 NCBI chrNW_004624804:9,609,777...9,643,670
Ensembl chrNW_004624804:9,610,308...9,641,933 		JBrowse link
G Vamp2 vesicle associated membrane protein 2 ISO RGD PMID:18431594 RGD:2312656 NCBI chrNW_004624786:10,723,791...10,727,654
Ensembl chrNW_004624786:10,724,964...10,727,649 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 3917
    regulatory pathway 2426
      homeostasis pathway 1267
        cardiovascular system homeostasis pathway 259
          vasopressin signaling pathway 21
            altered vasopressin signaling pathway + 0
            vasopressin signaling pathway via receptor type 1 + 5
            vasopressin signaling pathway via receptor type 2 + 17
paths to the root