mesangiolysis - Ontology Report - Rat Genome Database

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MAMMALIAN PHENOTYPE - ANNOTATIONS	{{ watchLinkText }}
The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:	mesangiolysis	go back to main search page
Accession:	MP:0011430	browse the term
Definition:	an injurious glomerular process that affects primarily the mesangium, starting with loosening and detachment of its matrix and progressing to dissolution/attenuation with degeneration of mesangial cells; mesangial cells may show only edema and vacuolization, or may undergo severe degeneration and necrosis
Synonyms:	exact_synonym:	dissolution of the mesangial matrix; mesangial cell degeneration

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Genes (16)

mesangiolysis

term browser

Symbol

Object Name

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

apolipoprotein E

NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113

G

B cell leukemia/lymphoma 2

NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004

G

C-type lectin domain family 2, member h

NCBI chr 6:128,639,348...128,654,337
Ensembl chr 6:128,639,348...128,654,337

G

cysteine rich transmembrane BMP regulator 1

NCBI chr17:78,507,602...78,684,021
Ensembl chr17:78,507,677...78,684,021

G

EH-domain containing 3

NCBI chr17:74,111,836...74,139,088
Ensembl chr17:74,111,129...74,139,089

G

EH-domain containing 4

NCBI chr 2:119,919,958...119,985,028
Ensembl chr 2:119,919,656...119,985,087

G

gene trap ROSA 26, Philippe Soriano

NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,054,294

G

insulin II

NCBI chr 7:142,232,393...142,233,463
Ensembl chr 7:142,232,393...142,297,118

G

integrin alpha 1

PMID:15277235 PMID:22297672

NCBI chr13:115,094,615...115,238,500
Ensembl chr13:115,089,632...115,238,500

G

integrin beta 1 (fibronectin receptor beta)

NCBI chr 8:129,412,135...129,460,060
Ensembl chr 8:129,412,135...129,459,681

G

kirre like nephrin family adhesion molecule 1

NCBI chr 3:86,985,900...87,082,084
Ensembl chr 3:86,985,900...87,082,054

G

leptin

NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876

G

leptin receptor

NCBI chr 4:101,574,393...101,676,375
Ensembl chr 4:101,574,601...101,672,549

G

nitric oxide synthase 3, endothelial cell

PMID:16971655 PMID:19036847

NCBI chr 5:24,569,772...24,589,472
Ensembl chr 5:24,569,808...24,589,472

G

nephrosis 2, podocin

PMID:14701729 PMID:18288100

NCBI chr 1:156,138,105...156,155,605
Ensembl chr 1:156,138,297...156,155,605

G

WT1 transcription factor

NCBI chr 2:104,956,874...105,003,959
Ensembl chr 2:104,956,874...105,003,961

Term paths to the root

Path 1
Term	Annotations
mammalian phenotype	16738
renal/urinary system phenotype	2078
abnormal renal/urinary system morphology	1730
abnormal kidney morphology	1546
abnormal nephron morphology	610
abnormal renal corpuscle morphology	444
abnormal renal glomerulus morphology	411
abnormal glomerular mesangium morphology	112
mesangiolysis	16

paths to the root