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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of cytokine production involved in inflammatory response
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Accession:GO:1900015 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of cytokine production involved in inflammatory response.
Synonyms:narrow_synonym: regulation of cytokine production involved in acute inflammatory response


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regulation of cytokine production involved in inflammatory response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX5 arachidonate 5-lipoxygenase involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:42,461,398...42,531,576
Ensembl chr10:45,639,946...45,710,016 		JBrowse link
G BAP1 BRCA1 associated protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:26119930) Ensembl
MGI		 PMID:26119930 GO_REF:0000107 NCBI chr 3:52,344,067...52,352,187
Ensembl chr 3:53,573,785...53,581,943 		JBrowse link
G LEP leptin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:120,230,896...120,248,602
Ensembl chr 7:132,885,011...132,901,519 		JBrowse link
G MAPK14 mitogen-activated protein kinase 14 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:35,586,847...35,683,041
Ensembl chr 6:36,788,233...36,871,114 		JBrowse link
G NOS2 nitric oxide synthase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:28,984,295...29,021,516
Ensembl chr17:29,471,510...29,617,093 		JBrowse link
G PER1 period circadian regulator 1 involved_in ISO PMID:24447840 UniProt PMID:24447840 RGD:8655527 NCBI chr17:43,502,080...43,518,098
Ensembl chr17:48,234,360...48,250,391 		JBrowse link
G PLD3 phospholipase D family member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:37,396,475...37,426,425
Ensembl chr19:45,910,035...45,939,343 		JBrowse link
G PLD4 phospholipase D family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:85,574,724...85,587,176
Ensembl chr14:105,360,584...105,369,247 		JBrowse link
G TREM2 triggering receptor expressed on myeloid cells 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:40,735,483...40,740,208
Ensembl chr 6:42,043,900...42,048,578 		JBrowse link
negative regulation of cytokine production involved in inflammatory response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCD1 ATP binding cassette subfamily D member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:143,275,165...143,295,283
Ensembl chr  X:153,162,412...153,182,424 		JBrowse link
G ABCD2 ATP binding cassette subfamily D member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:49,082,122...49,158,524
Ensembl chr12:49,941,914...50,011,140 		JBrowse link
G ADCY7 adenylate cyclase 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:30,507,836...30,581,068
Ensembl chr16:49,410,143...49,462,278 		JBrowse link
G APOD apolipoprotein D involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:192,852,887...192,868,233
Ensembl chr 3:203,152,476...203,168,060 		JBrowse link
G APPL2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:102,755,388...102,818,686
Ensembl chr12:106,151,969...106,206,879 		JBrowse link
G CHID1 chitinase domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:888,660...930,901
Ensembl chr11:929,278...977,082 		JBrowse link
G CUEDC2 CUE domain containing 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:24882011) MGI
Ensembl		 PMID:24882011 GO_REF:0000107 NCBI chr10:99,026,735...99,036,175
Ensembl chr10:102,492,412...102,502,107 		JBrowse link
G EPHB2 EPH receptor B2 ISO RGD PMID:33722292 RGD:127285641 NCBI chr 1:21,895,961...22,107,649
Ensembl chr 1:22,912,570...23,047,118 		JBrowse link
G EXTL3 exostosin like glycosyltransferase 3 involved_in ISO (PMID:28811323) UniProt PMID:28811323 NCBI chr 8:27,983,700...28,035,879
Ensembl chr 8:25,174,414...25,233,599 		JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit ISO RGD PMID:27690696 RGD:126781724 NCBI chr 7:140,536,962...140,613,104
Ensembl chr 7:153,017,590...153,059,726 		JBrowse link
G F2 coagulation factor II, thrombin involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:46,669,925...46,690,391
Ensembl chr11:47,227,891...47,249,157 		JBrowse link
G IL1R2 interleukin 1 receptor type 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23395675) Ensembl
MGI		 PMID:23395675 GO_REF:0000107 Ensembl chr2A:103,042,328...103,078,190 JBrowse link
G LILRB4 leukocyte immunoglobulin like receptor B4 involved_in ISO (PMID:19380766) ARUK-UCL PMID:19380766 NCBI chr19:51,606,681...51,612,751 JBrowse link
G LOC100990946 group 10 secretory phospholipase A2 acts_upstream_of_or_within ISO (PMID:26828067) MGI PMID:26828067 NCBI chr16:13,600,152...13,622,629 JBrowse link
G MACIR macrophage immunometabolism regulator involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:26316022) TreeGrafter
MGI		 PMID:26316022 GO_REF:0000118 NCBI chr 5:98,612,892...98,632,854
Ensembl chr 5:104,330,232...104,330,852 		JBrowse link
G MEFV MEFV innate immunity regulator, pyrin involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:2,175,858...2,191,056
Ensembl chr16:3,353,666...3,368,970 		JBrowse link
G NLRC3 NLR family CARD domain containing 3 involved_in ISO (MGI:5568884|PMID:24560620) UniProt PMID:24560620 MGI:5568884 NCBI chr16:2,463,940...2,487,961
Ensembl chr16:3,637,612...3,674,088 		JBrowse link
G NLRP7 NLR family pyrin domain containing 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:51,966,886...51,990,971
Ensembl chr19:60,662,184...60,677,844 		JBrowse link
G PDCD4 programmed cell death 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:107,465,084...107,493,285
Ensembl chr10:110,914,222...110,942,394 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha acts_upstream_of
involved_in		 ISO
IEA		 (PMID:31574452) ARUK-UCL
Ensembl		 PMID:31574452 GO_REF:0000107 Ensembl chr22:45,218,364...45,302,970 JBrowse link
G PSG9 pregnancy specific beta-1-glycoprotein 9 involved_in ISO (PMID:27389696) UniProt PMID:27389696 NCBI chr19:40,182,939...40,199,762 JBrowse link
G PYCARD PYD and CARD domain containing involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:23,764,386...23,765,732
Ensembl chr16:31,571,363...31,573,828 		JBrowse link
G SIRPA signal regulatory protein alpha involved_in ISO (MGI:3760575|PMID:17954568)
(MGI:6189251|PMID:23562609)		 ARUK-UCL PMID:17954568 PMID:23562609 MGI:3760575 MGI:6189251 NCBI chr20:2,006,994...2,052,894
Ensembl chr20:1,773,271...1,818,106 		JBrowse link
G SPINK7 serine peptidase inhibitor Kazal type 7 acts_upstream_of_or_within ISO (PMID:33722746) MGI PMID:33722746 NCBI chr 5:143,739,292...143,742,788
Ensembl chr 5:149,748,127...149,751,615 		JBrowse link
G TREM2 triggering receptor expressed on myeloid cells 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:40,735,483...40,740,208
Ensembl chr 6:42,043,900...42,048,578 		JBrowse link
G ZC3H12A zinc finger CCCH-type containing 12A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:36,743,341...36,753,261
Ensembl chr 1:38,093,917...38,103,556 		JBrowse link
positive regulation of cytokine production involved in inflammatory response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANKRD42 ankyrin repeat domain 42 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20547855) Ensembl
MGI		 PMID:20547855 GO_REF:0000107 NCBI chr11:78,257,158...78,326,216
Ensembl chr11:81,868,855...81,932,583 		JBrowse link
G APPL1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:57,161,299...57,206,672
Ensembl chr 3:58,370,430...58,415,258 		JBrowse link
G CARD9 caspase recruitment domain family member 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:107,432,709...107,446,271
Ensembl chr 9:136,416,279...136,424,756 		JBrowse link
G CD6 CD6 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:56,269,585...56,283,516
Ensembl chr11:59,675,221...59,722,916 		JBrowse link
G CD74 CD74 molecule involved_in ISO (PMID:23736979) AgBase PMID:23736979 NCBI chr 5:145,825,635...145,836,916
Ensembl chr 5:151,830,311...151,841,334 		JBrowse link
G CLEC7A C-type lectin domain containing 7A involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr12:10,161,780...10,174,943
Ensembl chr12:10,410,384...10,425,452 		JBrowse link
G GBP5 guanylate binding protein 5 involved_in ISO (MGI:5319585|PMID:22461501) UniProt PMID:22461501 MGI:5319585 NCBI chr 1:91,969,699...92,006,127
Ensembl chr 1:90,720,927...90,729,757 		JBrowse link
G GPSM3 G protein signaling modulator 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23280397) Ensembl
MGI		 PMID:23280397 GO_REF:0000107 NCBI chr 6:31,838,154...31,840,312
Ensembl chr 6:32,718,033...32,720,348 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:42,295,691...42,348,478
Ensembl chr14:60,552,374...60,604,885 		JBrowse link
G IL17A interleukin 17A acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:29734196)
(PMID:17982105)
(PMID:16785495)		 ARUK-UCL
MGI
Ensembl		 PMID:16785495 PMID:17982105 PMID:29734196 GO_REF:0000107 NCBI chr 6:51,736,269...51,740,538
Ensembl chr 6:53,004,820...53,009,074 		JBrowse link
G IL17B interleukin 17B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17982105) Ensembl
MGI		 PMID:17982105 GO_REF:0000107 NCBI chr 5:144,800,664...144,842,788
Ensembl chr 5:150,811,055...150,815,930 		JBrowse link
G IL17C interleukin 17C acts_upstream_of_or_within ISO (PMID:17982105) MGI PMID:17982105 NCBI chr16:69,347,233...69,353,562
Ensembl chr16:89,011,688...89,013,678 		JBrowse link
G IL17D interleukin 17D involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:2,030,234...2,049,965
Ensembl chr13:20,343,537...20,361,535 		JBrowse link
G IL17F interleukin 17F involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16785495)
(PMID:16785495), (PMID:17982105)		 Ensembl
MGI		 PMID:16785495 PMID:17982105 GO_REF:0000107 NCBI chr 6:51,789,210...51,797,470
Ensembl chr 6:53,057,318...53,065,124 		JBrowse link
G IL17RA interleukin 17 receptor A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16785495) Ensembl
MGI		 PMID:16785495 GO_REF:0000107 NCBI chr22:511,091...541,504
Ensembl chr22:15,950,463...15,974,865 		JBrowse link
G IL17RC interleukin 17 receptor C involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16785495) Ensembl
MGI		 PMID:16785495 GO_REF:0000107 NCBI chr 3:9,861,423...9,878,154
Ensembl chr 3:10,210,241...10,226,796 		JBrowse link
G IL6 interleukin 6 involved_in ISO (PMID:31886314) ARUK-UCL PMID:31886314 NCBI chr 7:23,415,922...23,420,767 JBrowse link
G KPNA6 karyopherin subunit alpha 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:28189564) Ensembl
MGI		 PMID:28189564 GO_REF:0000107 NCBI chr 1:31,394,159...31,462,821
Ensembl chr 1:32,406,326...32,471,488 		JBrowse link
G MAPK9 mitogen-activated protein kinase 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:175,437,167...175,495,469
Ensembl chr 5:182,748,381...182,795,135 		JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:38,036,565...38,041,014
Ensembl chr 3:38,319,024...38,323,572 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:30,955,976...30,995,451
Ensembl chr16:49,837,891...49,873,773 		JBrowse link
G PLA2G3 phospholipase A2 group III involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:28947740) Ensembl
MGI		 PMID:28947740 GO_REF:0000107 NCBI chr22:12,158,589...12,164,441
Ensembl chr22:29,995,364...30,001,160 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:14,928,689...15,003,644
Ensembl chr17:15,152,358...15,227,067 		JBrowse link
G TARM1 T cell-interacting, activating receptor on myeloid cells 1 involved_in ISO (MGI:5908526|PMID:26311901) UniProt PMID:26311901 MGI:5908526 NCBI chr19:51,002,643...51,014,597
Ensembl chr19:59,846,601...59,857,087 		JBrowse link
G TICAM1 TIR domain containing adaptor molecule 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr19:3,836,100...3,852,017
Ensembl chr19:4,787,557...4,790,206 		JBrowse link
G TICAM2 TIR domain containing adaptor molecule 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 5:110,935,649...110,960,019
Ensembl chr 5:116,734,092...116,734,799 		JBrowse link
G TLR3 toll like receptor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:178,238,352...178,256,264
Ensembl chr 4:190,446,487...190,462,728 		JBrowse link
G TLR4 toll like receptor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:88,827,495...88,840,458
Ensembl chr 9:117,180,550...117,190,711 		JBrowse link
G TLR6 toll like receptor 6 involved_in ISO (MGI:4438693|PMID:20037584) ARUK-UCL PMID:20037584 MGI:4438693 NCBI chr 4:33,153,151...33,174,053
Ensembl chr 4:39,009,103...39,011,490 		JBrowse link
G TNF tumor necrosis factor acts_upstream_of
involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:31824476)
(PMID:23608026)		 ARUK-UCL
Ensembl		 PMID:23608026 PMID:31824476 GO_REF:0000107 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16442
    multicellular organismal process 7217
      cytokine production 808
        regulation of cytokine production 800
          regulation of cytokine production involved in inflammatory response 64
            negative regulation of cytokine production involved in inflammatory response 26
            positive regulation of cytokine production involved in inflammatory response 30
Path 2
Term Annotations click to browse term
  biological_process 16442
    biological regulation 11463
      regulation of biological process 11110
        regulation of cellular process 10606
          regulation of cellular metabolic process 5552
            regulation of cellular biosynthetic process 4968
              regulation of macromolecule biosynthetic process 4870
                regulation of gene expression 4752
                  regulation of cytokine production 800
                    regulation of cytokine production involved in inflammatory response 64
                      negative regulation of cytokine production involved in inflammatory response 26
                      positive regulation of cytokine production involved in inflammatory response 30
paths to the root