MACIR (macrophage immunometabolism regulator) - Rat Genome Database

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Gene: MACIR (macrophage immunometabolism regulator) Pan paniscus
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Symbol: MACIR
Name: macrophage immunometabolism regulator
RGD ID: 11997072
Description: INVOLVED IN epithelial cell migration (ortholog); fibroblast migration (ortholog); negative regulation of cytokine production involved in inflammatory response (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); Colonic Neoplasms (ortholog); COVID-19 (ortholog); FOUND IN ciliary transition zone (inferred); cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: C5H5orf30; chromosome 5 C5orf30 homolog; chromosome 5 open reading frame, human C5orf30; UNC119-binding protein C5orf30 homolog; UNC119-binding protein C5orf30-like
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2498,541,893 - 98,561,641 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1596,695,534 - 96,715,289 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0598,612,892 - 98,632,854 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15104,313,494 - 104,332,681 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5104,330,232 - 104,330,852 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
MACIR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2498,541,893 - 98,561,641 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1596,695,534 - 96,715,289 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0598,612,892 - 98,632,854 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15104,313,494 - 104,332,681 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5104,330,232 - 104,330,852 (+)Ensemblpanpan1.1panPan2
MACIR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385103,258,374 - 103,278,660 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5103,258,763 - 103,278,660 (+)EnsemblGRCh38hg38GRCh38
GRCh375102,594,075 - 102,614,361 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365102,622,341 - 102,642,260 (+)NCBINCBI36Build 36hg18NCBI36
Celera598,542,288 - 98,562,209 (+)NCBICelera
Cytogenetic Map5q21.1NCBI
HuRef597,775,822 - 97,795,742 (+)NCBIHuRef
CHM1_15102,027,108 - 102,047,027 (+)NCBICHM1_1
T2T-CHM13v2.05103,766,495 - 103,786,818 (+)NCBIT2T-CHM13v2.0
Macir
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39197,571,627 - 97,589,743 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl197,534,043 - 97,589,799 (-)EnsemblGRCm39 Ensembl
GRCm38197,643,902 - 97,662,018 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl197,606,318 - 97,662,074 (-)EnsemblGRCm38mm10GRCm38
MGSCv37199,540,479 - 99,558,595 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36199,474,309 - 99,492,382 (-)NCBIMGSCv36mm8
Celera1100,523,076 - 100,541,194 (-)NCBICelera
Cytogenetic Map1DNCBI
cM Map147.76NCBI
Macir
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr89105,868,072 - 105,888,128 (+)NCBIGRCr8
mRatBN7.2998,420,760 - 98,440,818 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl998,420,376 - 98,441,733 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx9106,834,539 - 106,854,561 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.09111,962,313 - 111,982,335 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.09110,305,924 - 110,325,948 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.09111,327,333 - 111,347,428 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl9111,327,402 - 111,347,430 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.09110,878,815 - 110,898,589 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4997,216,277 - 97,236,238 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera995,862,440 - 95,882,884 (+)NCBICelera
Cytogenetic Map9q36NCBI
Macir
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541810,752,250 - 10,767,791 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541810,752,250 - 10,767,791 (-)NCBIChiLan1.0ChiLan1.0
MACIR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.137,956,865 - 7,968,964 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha39,358,340 - 9,377,572 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.037,844,435 - 7,863,767 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl37,844,463 - 7,862,952 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.137,785,357 - 7,804,615 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.037,805,599 - 7,823,519 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.037,964,146 - 7,983,424 (-)NCBIUU_Cfam_GSD_1.0
Macir
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213163,088,172 - 163,107,524 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365231,275,214 - 1,292,854 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365231,273,812 - 1,292,837 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MACIR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2108,733,357 - 108,753,275 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12108,733,347 - 108,753,276 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22112,804,239 - 112,822,920 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MACIR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1236,695,131 - 6,714,925 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl236,712,171 - 6,712,791 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660367,609,545 - 7,629,192 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Macir
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474321,372,278 - 21,387,871 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474321,372,253 - 21,389,202 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000023615   ⟹   ENSPPAP00000005175
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl5104,330,232 - 104,330,852 (+)Ensembl
RefSeq Acc Id: XM_003828310   ⟹   XP_003828358
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2498,542,986 - 98,561,641 (+)NCBI
NHGRI_mPanPan1596,696,633 - 96,715,289 (+)NCBI
Mhudiblu_PPA_v0598,613,680 - 98,632,854 (+)NCBI
PanPan1.15104,313,729 - 104,332,681 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008953679   ⟹   XP_008951927
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2498,542,238 - 98,561,641 (+)NCBI
NHGRI_mPanPan1596,695,887 - 96,715,289 (+)NCBI
Mhudiblu_PPA_v0598,613,164 - 98,632,854 (+)NCBI
PanPan1.15104,313,494 - 104,332,681 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008953680   ⟹   XP_008951928
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2498,543,123 - 98,561,641 (+)NCBI
NHGRI_mPanPan1596,696,777 - 96,715,289 (+)NCBI
Mhudiblu_PPA_v0598,614,053 - 98,632,854 (+)NCBI
PanPan1.15104,314,286 - 104,332,681 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008953682   ⟹   XP_008951930
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2498,542,238 - 98,561,641 (+)NCBI
NHGRI_mPanPan1596,695,887 - 96,715,289 (+)NCBI
Mhudiblu_PPA_v0598,613,164 - 98,632,854 (+)NCBI
PanPan1.15104,313,503 - 104,332,681 (+)NCBI
Sequence:
RefSeq Acc Id: XM_034960314   ⟹   XP_034816205
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2498,541,893 - 98,561,641 (+)NCBI
NHGRI_mPanPan1596,695,534 - 96,715,289 (+)NCBI
Mhudiblu_PPA_v0598,612,892 - 98,632,854 (+)NCBI
Protein Sequences
Protein RefSeqs XP_003828358 (Get FASTA)   NCBI Sequence Viewer  
  XP_008951927 (Get FASTA)   NCBI Sequence Viewer  
  XP_008951928 (Get FASTA)   NCBI Sequence Viewer  
  XP_008951930 (Get FASTA)   NCBI Sequence Viewer  
  XP_034816205 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000005175.1
RefSeq Acc Id: XP_008951927   ⟸   XM_008953679
- UniProtKB: A0A2R8ZMK4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008951930   ⟸   XM_008953682
- UniProtKB: A0A2R8ZMK4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003828358   ⟸   XM_003828310
- UniProtKB: A0A2R8ZMK4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008951928   ⟸   XM_008953680
- UniProtKB: A0A2R8ZMK4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034816205   ⟸   XM_034960314
- UniProtKB: A0A2R8ZMK4 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000005175   ⟸   ENSPPAT00000023615


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000021533 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000023615.1 UniProtKB/TrEMBL
InterPro UNC119-bd UniProtKB/TrEMBL
KEGG Report pps:100969358 UniProtKB/TrEMBL
NCBI Gene C5H5orf30 ENTREZGENE
PANTHER MACROPHAGE IMMUNOMETABOLISM REGULATOR UniProtKB/TrEMBL
  PTHR31224 UniProtKB/TrEMBL
Pfam UNC119_bdg UniProtKB/TrEMBL
UniProt A0A2R8ZMK4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-11-05 MACIR  macrophage immunometabolism regulator  C5H5orf30  chromosome 5 C5orf30 homolog  Symbol and/or name change 5135510 APPROVED
2018-05-08 C5H5orf30  chromosome 5 C5orf30 homolog    chromosome 5 open reading frame, human C5orf30  Symbol and/or name change 5135510 APPROVED