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Gene: IL17B (interleukin 17B) Pan paniscus

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Symbol:

IL17B

Name:

interleukin 17B

RGD ID:

11749937

Description:

ENCODES a protein that exhibits cytokine activity (inferred); INVOLVED IN inflammatory response (inferred); positive regulation of cytokine production involved in inflammatory response (inferred); signal transduction (inferred); ASSOCIATED WITH familial adenomatous polyposis 1 (ortholog); Hereditary Neoplastic Syndromes (ortholog); Keratoconus 1 (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

interleukin-17B

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	IL17B (interleukin 17B)	NCBI	Ortholog
Mus musculus (house mouse):	Il17b (interleukin 17B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Il17b (interleukin 17B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Il17b (interleukin 17B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	IL17B (interleukin 17B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Il17b (interleukin 17B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	IL17B (interleukin 17B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	IL17B (interleukin 17B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Il17b (interleukin 17B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	144,604,299 - 144,607,629 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	5	142,743,848 - 142,763,536 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	144,800,664 - 144,842,788 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	150,811,055 - 150,840,085 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	150,811,055 - 150,815,930 (-)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
IL17B	Bonobo	familial adenomatous polyposis 1		ISO	IL17B (Homo sapiens)	8554872	ClinVar Annotator: match by term: Familial adenomatous polyposis 1	ClinVar	PMID:17963004 more ...
IL17B	Bonobo	Hereditary Neoplastic Syndromes		ISO	IL17B (Homo sapiens)	8554872	ClinVar Annotator: match by term: Hereditary cancer-predisposing syndrome	ClinVar	PMID:17963004 more ...
IL17B	Bonobo	Keratoconus 1		ISO	IL17B (Homo sapiens)	8554872	ClinVar Annotator: match by term: Keratoconus 1	ClinVar
IL17B	Bonobo	Neurodevelopmental Disorders		ISO	IL17B (Homo sapiens)	8554872	ClinVar Annotator: match by term: Neurodevelopmental disorder	ClinVar	PMID:25741868

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
IL17B	Bonobo	inflammatory response	involved_in	IEA	InterPro:IPR020440	150520179		InterPro	GO_REF:0000002
IL17B	Bonobo	positive regulation of cytokine production involved in inflammatory response	acts_upstream_of_or_within	IEA	UniProtKB:Q9QXT6 and ensembl:ENSMUSP00000025471	150520179		Ensembl	GO_REF:0000107
IL17B	Bonobo	signal transduction	involved_in	IEA	GO:0005125	150520179		GOC	GO_REF:0000108

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
IL17B	Bonobo	extracellular region	located_in	IEA	UniProtKB-SubCell:SL-0243	150520179		UniProt	GO_REF:0000044
IL17B	Bonobo	extracellular region	located_in	IEA	UniProtKB-KW:KW-0964	150520179		UniProt	GO_REF:0000043
IL17B	Bonobo	extracellular region	located_in	IEA	InterPro:IPR010345 and InterPro:IPR020440	150520179		InterPro	GO_REF:0000002
IL17B	Bonobo	extracellular space	located_in	IEA	UniProtKB-KW:KW-0202	150520179		UniProt	GO_REF:0000043

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
IL17B	Bonobo	cytokine activity	enables	IEA	UniProtKB:Q9QXT6 and ensembl:ENSMUSP00000025471	150520179		Ensembl	GO_REF:0000107
IL17B	Bonobo	cytokine activity	enables	IEA	UniProtKB-KW:KW-0202	150520179		UniProt	GO_REF:0000043
IL17B	Bonobo	cytokine activity	enables	IEA	InterPro:IPR010345 and InterPro:IPR020440	150520179		InterPro	GO_REF:0000002
IL17B	Bonobo	cytokine activity	enables	IEA	ARBA:ARBA00027187	150520179		UniProt	GO_REF:0000117

PMID:22301074

IL17B
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	144,604,299 - 144,607,629 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	5	142,743,848 - 142,763,536 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	144,800,664 - 144,842,788 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	150,811,055 - 150,840,085 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	150,811,055 - 150,815,930 (-)	Ensembl	panpan1.1		panPan2

IL17B
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	149,374,267 - 149,404,202 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	149,371,324 - 149,404,202 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	5	148,753,830 - 148,783,765 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	148,734,023 - 148,739,031 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	5	148,734,024 - 148,739,031	NCBI
Celera	5	144,835,805 - 144,840,813 (-)	NCBI		Celera
Cytogenetic Map	5	q32	NCBI
HuRef	5	143,900,155 - 143,905,163 (-)	NCBI		HuRef
CHM1_1	5	148,186,259 - 148,191,267 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	5	149,909,114 - 149,939,047 (-)	NCBI		T2T-CHM13v2.0

Il17b
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	18	61,821,006 - 61,825,609 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	18	61,817,958 - 61,825,609 (+)	Ensembl		GRCm39 Ensembl
GRCm38	18	61,687,935 - 61,692,538 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	18	61,684,887 - 61,692,538 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	18	61,847,589 - 61,852,191 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	18	61,813,304 - 61,817,906 (+)	NCBI		MGSCv36	mm8
Celera	18	62,970,900 - 62,975,972 (+)	NCBI		Celera
Cytogenetic Map	18	E1	NCBI
cM Map	18	34.67	NCBI

Il17b
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	18	57,411,532 - 57,415,903 (+)	NCBI		GRCr8
mRatBN7.2	18	55,141,194 - 55,145,565 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	18	55,141,194 - 55,145,565 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	18	57,234,781 - 57,239,079 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	18	57,949,431 - 57,953,743 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	18	55,765,055 - 55,769,426 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	18	57,011,575 - 57,016,009 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	18	57,011,575 - 57,016,009 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	18	56,240,488 - 56,244,922 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	18	57,665,293 - 57,669,668 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	18	57,739,647 - 57,741,775 (+)	NCBI
Celera	18	53,290,941 - 53,295,289 (+)	NCBI		Celera
Cytogenetic Map	18	q12.1	NCBI

Il17b
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955415	5,041,375 - 5,047,449 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955415	5,037,270 - 5,047,405 (+)	NCBI	ChiLan1.0	ChiLan1.0

IL17B
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	4	59,578,568 - 59,584,069 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	4	59,543,080 - 59,583,968 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	4	59,341,309 - 59,352,992 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	4	60,058,822 - 60,070,520 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	4	60,060,397 - 60,066,539 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	4	59,845,455 - 59,857,144 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	4	59,960,072 - 59,971,763 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	4	60,490,476 - 60,502,167 (+)	NCBI		UU_Cfam_GSD_1.0

Il17b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	143,908,738 - 143,915,822 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936504	5,482,972 - 5,489,899 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936504	5,485,009 - 5,489,788 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

IL17B
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	150,541,180 - 150,545,367 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	150,513,611 - 150,583,640 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	157,279,046 - 157,349,566 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

IL17B
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	23	51,992,877 - 52,001,280 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	23	51,993,258 - 51,998,043 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666034	25,748,904 - 25,753,870 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Il17b
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624774	8,732,471 - 8,739,331 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624774	8,733,264 - 8,763,150 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.


RefSeq Transcripts	XM_003829044	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSPPAT00000045169 ⟹ ENSPPAP00000022359

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	5	150,811,055 - 150,815,930 (-)	Ensembl

RefSeq Acc Id:

XM_003829044 ⟹ XP_003829092

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	4	144,604,299 - 144,607,629 (-)	NCBI
NHGRI_mPanPan1	5	142,743,848 - 142,747,178 (-)	NCBI
Mhudiblu_PPA_v0	5	144,800,664 - 144,805,557 (-)	NCBI
PanPan1.1	5	150,811,055 - 150,815,931 (-)	NCBI

Sequence:

show sequence

TTCCAGGCGGGCAGCAGCTGCAGGCTGACCTTGCAGCTTGGCGGAATGGACTGGCCTCACAACCTGCTGTTTCTTCTTACCATTTCCATCTTCCTGGGGCTGGGCCAGCCCAGGAGCCCCAAAAGCAA
GAGGAAGGGGCAAGGGCGGCCTGGGCCCCTGGCCCCTGGCCCTCACCAGGTGCCACTGGACCTGGTGTCACGGATGAAACCGTATGCCCGCATGGAGGAGTATGAGAGGAACATCGAGGAGATGGTGG
CCCAGCTGAGGAACAGCTCAGAGCTGGCCCAGAGAAAGTGTGAGGTCAACTTGCAGCTGTGGATGTCCAACAAGAGGAGCCTGTCTCCCTGGGGCTACAGCATCAACCACGACCCCAGCCGTATCCCT
GTGGACCTGCCGGAGGCACGGTGCCTGTGTCTGGGCTGTGTGAACCCCTTCACCATGCAGGAGGACCGCAGCATGGTGAGCGTGCCGGTGTTCAGCCAGGTTCCTGTGCGCCGCCGCCTCTGCCCGCC
ACCGCCCCGCACAGGGCCTTGCCGCCAGCGCGCAGTCATGGAGACCATCGCTGTGGGCTGCACCTGCATCTTCTGAATCACCTGGCCCAGAAGCCAGGCCAGCAGCCCAAGACCATCCTCCTTGCACC
TTTGTGCCAAGAAAGGCCTATGAAAAGTAAACACTGACTTTTGAAAGCAA

hide sequence


Protein RefSeqs	XP_003829092	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000022359.1

RefSeq Acc Id:	XP_003829092 ⟸ XM_003829044
- Sequence:	show sequence MDWPHNLLFLLTISIFLGLGQPRSPKSKRKGQGRPGPLAPGPHQVPLDLVSRMKPYARMEEYERNIEEMVAQLRNSSELAQRKCEVNLQLWMSNKRSLSPWGYSINHDPSRIPVDLPEARCLCLGCVN PFTMQEDRSMVSVPVFSQVPVRRRLCPPPPRTGPCRQRAVMETIAVGCTCIF hide sequence

Ensembl Acc Id:

ENSPPAP00000022359 ⟸ ENSPPAT00000045169

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000034378	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000045169.1	UniProtKB/TrEMBL
Gene3D-CATH	2.10.90.10	UniProtKB/TrEMBL
InterPro	Cystine-knot_cytokine	UniProtKB/TrEMBL
	IL-17_chr	UniProtKB/TrEMBL
	IL-17_fam	UniProtKB/TrEMBL
KEGG Report	pps:100980380	UniProtKB/TrEMBL
NCBI Gene	IL17B	ENTREZGENE
Pfam	IL17	UniProtKB/TrEMBL
PRINTS	INTRLEUKIN17	UniProtKB/TrEMBL
Superfamily-SCOP	SSF57501	UniProtKB/TrEMBL
UniProt	A0A2R9AYH3_PANPA	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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