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ONTOLOGY REPORT - ANNOTATIONS

Term:transmembrane receptor protein tyrosine kinase activator activity
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Accession:GO:0030297 term browser browse the term
Definition:Binds to and increases the activity of a transmembrane receptor protein tyrosine kinase.


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transmembrane receptor protein tyrosine kinase activator activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALKAL1 ALK and LTK ligand 1 enables IDA (PMID:34646012), (PMID:34819673) UniProt PMID:34646012 PMID:34819673 NCBI chr 8:52,534,037...52,565,430
Ensembl chr 8:52,534,037...52,565,430 		JBrowse link
G ALKAL2 ALK and LTK ligand 2 enables IDA (PMID:30061385), (PMID:34646012), (PMID:34819673) UniProt PMID:30061385 PMID:34646012 PMID:34819673 NCBI chr 2:279,558...288,091
Ensembl chr 2:279,558...288,851 		JBrowse link
G ANGPT4 angiopoietin 4 enables IDA (PMID:10051567), (PMID:15851516) UniProt PMID:10051567 PMID:15851516 NCBI chr20:869,900...916,334
Ensembl chr20:869,900...916,334 		JBrowse link
G AREG amphiregulin enables IDA
IEA		 (PMID:8702723) MGI
Ensembl		 PMID:8702723 GO_REF:0000107 NCBI chr 4:74,445,136...74,455,005
Ensembl chr 4:74,445,136...74,455,005 		JBrowse link
G BTC betacellulin enables IDA
IEA		 (PMID:12399441), (PMID:9168114) MGI
Ensembl		 PMID:9168114 PMID:12399441 GO_REF:0000107 NCBI chr 4:74,744,759...74,794,523
Ensembl chr 4:74,744,759...74,794,523 		JBrowse link
G DGKQ diacylglycerol kinase theta enables IGI (PMID:22732145) ParkinsonsUK-UCL PMID:22732145 NCBI chr 4:958,887...973,569
Ensembl chr 4:958,887...986,895 		JBrowse link
G EFNA5 ephrin A5 enables NAS (PMID:19036963) BHF-UCL PMID:19036963 NCBI chr 5:107,376,894...107,670,937
Ensembl chr 5:107,376,894...107,670,937 		JBrowse link
G EGF epidermal growth factor enables TAS
IEA
IDA		 (PMID:9712850)
(PMID:11336639)		 UniProt
Ensembl
MGI		 PMID:9712850 PMID:11336639 GO_REF:0000107 NCBI chr 4:109,912,883...110,013,766
Ensembl chr 4:109,912,883...110,013,766 		JBrowse link
G EGFR epidermal growth factor receptor enables IEA Ensembl GO_REF:0000107 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
G EPGN epithelial mitogen enables IEA Ensembl GO_REF:0000107 NCBI chr 4:74,308,470...74,316,789
Ensembl chr 4:74,308,470...74,316,789 		JBrowse link
G EREG epiregulin enables IDA
IEA		 (PMID:28783046), (PMID:9556621) MGI
Ensembl		 PMID:9556621 PMID:28783046 GO_REF:0000107 NCBI chr 4:74,365,145...74,388,749
Ensembl chr 4:74,365,145...74,388,749 		JBrowse link
G GREM1 gremlin 1, DAN family BMP antagonist enables ISS
IEA		 BHF-UCL
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr15:32,718,004...32,745,106
Ensembl chr15:32,718,004...32,745,106 		JBrowse link
G HBEGF heparin binding EGF like growth factor enables IDA
IEA		 (PMID:8702723) MGI
Ensembl		 PMID:8702723 GO_REF:0000107 NCBI chr 5:140,332,843...140,346,603
Ensembl chr 5:140,332,843...140,346,603 		JBrowse link
G IGF1 insulin like growth factor 1 enables ISO (PMID:32697974)
(PMID:35647546)		 MGI PMID:32697974 PMID:35647546 NCBI chr12:102,395,874...102,481,839
Ensembl chr12:102,395,874...102,481,744 		JBrowse link
G IGF2 insulin like growth factor 2 enables IEA Ensembl GO_REF:0000107 NCBI chr11:2,129,117...2,149,566
Ensembl chr11:2,129,112...2,158,391 		JBrowse link
G NGF nerve growth factor enables ISO (MGI:5426777|PMID:19036963), (PMID:27655914) MGI PMID:19036963 PMID:27655914 MGI:5426777 NCBI chr 1:115,285,917...115,338,249
Ensembl chr 1:115,285,904...115,338,770 		JBrowse link
G NRG1 neuregulin 1 enables IC
NAS		 (PMID:9553078)
(PMID:1348215), (PMID:1350381)		 BHF-UCL
UniProt		 PMID:1348215 PMID:1350381 PMID:9553078 NCBI chr 8:31,639,245...32,774,046
Ensembl chr 8:31,639,222...32,855,666 		JBrowse link
G NRG3 neuregulin 3 enables NAS (PMID:9275162) UniProt PMID:9275162 NCBI chr10:81,875,194...82,987,179
Ensembl chr10:81,875,194...82,987,179 		JBrowse link
G TGFA transforming growth factor alpha enables IEA Ensembl GO_REF:0000107 NCBI chr 2:70,447,284...70,553,826
Ensembl chr 2:70,447,284...70,554,193 		JBrowse link
G VEGFA vascular endothelial growth factor A enables IDA (PMID:20497126) BHF-UCL PMID:20497126 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 19567
    molecular function regulator activity 2265
      signaling receptor regulator activity 608
        signaling receptor activator activity 549
          transmembrane receptor protein tyrosine kinase activator activity 20
Path 2
Term Annotations click to browse term
  molecular_function 19567
    molecular function regulator activity 2265
      enzyme regulator activity 1402
        enzyme activator activity 648
          kinase activator activity 153
            protein kinase activator activity 144
              protein tyrosine kinase activator activity 34
                transmembrane receptor protein tyrosine kinase activator activity 20
paths to the root