Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:telomerase holoenzyme complex
go back to main search page
Accession:GO:0005697 term browser browse the term
Definition:Telomerase is a ribonucleoprotein enzyme complex, with a minimal catalytic core composed of a catalytic reverse transcriptase subunit and an RNA subunit that provides the template for telomeric DNA addition. In vivo, the holoenzyme complex often contains additional subunits.


show annotations for term's descendants           Sort by:
telomerase holoenzyme complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acd ACD, shelterin complex subunit and telomerase recruitment factor part_of IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr19:33,586,739...33,589,481
Ensembl chr19:33,586,745...33,589,461 		JBrowse link
G Dkc1 dyskerin pseudouridine synthase 1 part_of ISO
ISS		 (PMID:12135483), (PMID:18082603), (PMID:29695869)
GO_REF:0000024		 RGD
UniProt		 PMID:12135483 PMID:18082603 PMID:29695869 GO_REF:0000024
G Gar1 GAR1 ribonucleoprotein part_of ISO
ISS		 (PMID:29695869)
GO_REF:0000024		 RGD
UniProt		 PMID:29695869 GO_REF:0000024 NCBI chr 2:218,375,231...218,382,509
Ensembl chr 2:218,375,353...218,382,524 		JBrowse link
G Gnl3l G protein nucleolar 3 like part_of ISO (PMID:18082603) RGD PMID:18082603 NCBI chr  X:19,961,277...19,994,454
Ensembl chr  X:19,958,603...19,994,508 		JBrowse link
G Hnrnpc heterogeneous nuclear ribonucleoprotein C part_of ISO (PMID:18082603) RGD PMID:18082603 NCBI chr15:24,779,593...24,809,213
Ensembl chr15:24,779,450...24,809,183 		JBrowse link
G Hnrnpu heterogeneous nuclear ribonucleoprotein U part_of ISO
IEA		 (PMID:18082603)
GO_REF:0000107		 RGD
Ensembl		 PMID:18082603 GO_REF:0000107 NCBI chr13:90,069,058...90,086,905
Ensembl chr13:90,074,181...90,086,588 		JBrowse link
G Lsm11 LSM11, U7 small nuclear RNA associated part_of ISO (PMID:18082603) RGD PMID:18082603 NCBI chr10:30,367,841...30,385,956
Ensembl chr10:30,370,727...30,385,944 		JBrowse link
G Nat10 N-acetyltransferase 10 part_of ISO (PMID:18082603) RGD PMID:18082603 NCBI chr 3:90,111,643...90,149,891
Ensembl chr 3:90,111,645...90,149,927 		JBrowse link
G Nhp2 NHP2 ribonucleoprotein part_of ISO (PMID:18082603), (PMID:29695869) RGD PMID:18082603 PMID:29695869 NCBI chr10:35,877,057...35,880,399
Ensembl chr10:35,877,054...35,882,545 		JBrowse link
G Nop10 NOP10 ribonucleoprotein part_of ISO (PMID:18082603), (PMID:29695869) RGD PMID:18082603 PMID:29695869 NCBI chr 3:99,066,857...99,067,942
Ensembl chr 3:99,066,857...99,067,942 		JBrowse link
G Nvl nuclear VCP-like part_of ISO (PMID:22226966) RGD PMID:22226966 NCBI chr13:92,851,023...92,906,749
Ensembl chr13:92,853,650...92,906,049 		JBrowse link
G Ptges3 prostaglandin E synthase 3 part_of ISO (PMID:12135483) RGD PMID:12135483 NCBI chr 7:490,698...507,759
Ensembl chr 7:490,656...508,084 		JBrowse link
G Smg5 SMG5 nonsense mediated mRNA decay factor part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:173,804,987...173,832,102
Ensembl chr 2:173,805,019...173,832,102 		JBrowse link
G Smg6 SMG6 nonsense mediated mRNA decay factor part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:59,786,258...60,014,395
Ensembl chr10:59,786,258...60,014,395 		JBrowse link
G Smg7 SMG7 nonsense mediated mRNA decay factor part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:64,986,145...65,050,698
Ensembl chr13:64,987,434...65,050,582 		JBrowse link
G Snrpb small nuclear ribonucleoprotein polypeptides B and B1 part_of ISO (PMID:18082603) RGD PMID:18082603 NCBI chr 3:117,369,816...117,379,344
Ensembl chr 3:117,370,100...117,379,339 		JBrowse link
G Snrpd3 small nuclear ribonucleoprotein D3 polypeptide part_of ISO (PMID:18082603) RGD PMID:18082603 NCBI chr20:13,130,112...13,145,947
Ensembl chr20:13,130,119...13,145,978 		JBrowse link
G Snrpe small nuclear ribonucleoprotein polypeptide E part_of ISO (PMID:18082603) RGD PMID:18082603 NCBI chr13:45,050,986...45,057,231
Ensembl chr13:45,050,986...45,057,310
Ensembl chr 8:45,050,986...45,057,310 		JBrowse link
G Tep1 telomerase associated protein 1 part_of IEA
ISO
IDA
IBA		 GO_REF:0000107
(PMID:12135483)
PMID:9118230
(MGI:85699|PMID:9020079)
GO_REF:0000033		 Ensembl
RGD
GO_Central		 PMID:9020079 PMID:12135483 PMID:9118230 GO_REF:0000033 GO_REF:0000107 MGI:85699, RGD:1299082 NCBI chr15:24,045,876...24,093,526
Ensembl chr15:24,045,878...24,093,526 		JBrowse link
G Terc telomerase RNA component part_of ISO UniProtKB:O14746 (PMID:19701182) RGD PMID:19701182 NCBI chr 2:112,815,654...112,816,041 JBrowse link
G Tert telomerase reverse transcriptase part_of ISO
ISS		 RNAcentral:URS00004A7003_9606 (PMID:12135483), (PMID:18082603), (PMID:19701182), (PMID:29695869)
GO_REF:0000024		 RGD
UniProt		 PMID:12135483 PMID:18082603 PMID:19701182 PMID:29695869 GO_REF:0000024 NCBI chr 1:29,637,213...29,659,561
Ensembl chr 1:29,637,506...29,659,561 		JBrowse link
G Wrap53 WD repeat containing, antisense to TP53 part_of ISO
ISS		 (PMID:19179534), (PMID:26170453), (PMID:29695869), (PMID:29804836)
GO_REF:0000024		 RGD
UniProt		 PMID:19179534 PMID:26170453 PMID:29695869 PMID:29804836 GO_REF:0000024 NCBI chr10:54,282,092...54,299,908
Ensembl chr10:54,282,105...54,298,929 		JBrowse link
box H/ACA telomerase RNP complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dkc1 dyskerin pseudouridine synthase 1 part_of ISO (PMID:18082603) RGD PMID:18082603
G Gar1 GAR1 ribonucleoprotein part_of ISO
IEA		 (PMID:10757788)
GO_REF:0000107		 RGD
Ensembl		 PMID:10757788 GO_REF:0000107 NCBI chr 2:218,375,231...218,382,509
Ensembl chr 2:218,375,353...218,382,524 		JBrowse link
G Nhp2 NHP2 ribonucleoprotein part_of ISO (PMID:18082603) RGD PMID:18082603 NCBI chr10:35,877,057...35,880,399
Ensembl chr10:35,877,054...35,882,545 		JBrowse link
G Nop10 NOP10 ribonucleoprotein part_of ISO (PMID:18082603) RGD PMID:18082603 NCBI chr 3:99,066,857...99,067,942
Ensembl chr 3:99,066,857...99,067,942 		JBrowse link
G Terc telomerase RNA component part_of ISO (PMID:10757788), (PMID:18082603) RGD PMID:10757788 PMID:18082603 NCBI chr 2:112,815,654...112,816,041 JBrowse link
telomerase catalytic core complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Terc telomerase RNA component part_of ISO (PMID:11313459), (PMID:18082603), (PMID:19701182), (PMID:9398860), (PMID:9443919) RGD PMID:9398860 PMID:9443919 PMID:11313459 PMID:18082603 PMID:19701182 NCBI chr 2:112,815,654...112,816,041 JBrowse link
G Tert telomerase reverse transcriptase part_of ISO
IBA		 RNAcentral:URS00004A7003_9606 (PMID:11313459), (PMID:16507993), (PMID:17940095), (PMID:18082603), (PMID:19701182), (PMID:9398860), (PMID:9443919)
GO_REF:0000033
(MGI:3588604|PMID:16037417)		 RGD
GO_Central		 PMID:9398860 PMID:9443919 PMID:11313459 PMID:16037417 PMID:16507993 More... GO_REF:0000033 MGI:3588604 NCBI chr 1:29,637,213...29,659,561
Ensembl chr 1:29,637,506...29,659,561 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20713
    protein-containing complex 6606
      catalytic complex 1788
        telomerase holoenzyme complex 22
          box H/ACA telomerase RNP complex 5
          telomerase catalytic core complex 2
Path 2
Term Annotations click to browse term
  cellular_component 20713
    cellular anatomical entity 20472
      organelle 13843
        membrane-bounded organelle 12439
          intracellular membrane-bounded organelle 11893
            nucleus 7467
              nuclear protein-containing complex 1303
                telomerase holoenzyme complex 22
                  box H/ACA telomerase RNP complex 5
                  telomerase catalytic core complex 2
paths to the root