Nvl (nuclear VCP-like) - Rat Genome Database

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Gene: Nvl (nuclear VCP-like) Rattus norvegicus
Analyze
Symbol: Nvl
Name: nuclear VCP-like
RGD ID: 1311270
Description: Predicted to enable ATP binding activity; ATP hydrolysis activity; and preribosome binding activity. Predicted to be involved in several processes, including positive regulation of telomerase activity; regulation of protein localization to nucleolus; and ribosome biogenesis. Predicted to be located in nucleoplasm. Predicted to be part of telomerase holoenzyme complex. Predicted to be active in nucleus. Predicted to colocalize with nucleolus. Orthologous to human NVL (nuclear VCP like); PARTICIPATES IN ribosome biogenesis pathway; INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC289323; nuclear valosin-containing protein-like
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21392,851,023 - 92,906,749 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1392,853,650 - 92,906,049 (-)Ensembl
Rnor_6.01399,410,026 - 99,468,783 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1399,410,026 - 99,468,778 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013104,407,045 - 104,465,204 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41396,862,759 - 96,917,215 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11397,051,898 - 97,105,918 (-)NCBI
Celera1392,394,917 - 92,447,334 (-)NCBICelera
Cytogenetic Map13q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:15469983   PMID:16782053   PMID:19946888   PMID:22226966   PMID:22658674   PMID:26166824   PMID:26456651   PMID:29107693  


Genomics

Comparative Map Data
Nvl
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21392,851,023 - 92,906,749 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1392,853,650 - 92,906,049 (-)Ensembl
Rnor_6.01399,410,026 - 99,468,783 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1399,410,026 - 99,468,778 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013104,407,045 - 104,465,204 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41396,862,759 - 96,917,215 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11397,051,898 - 97,105,918 (-)NCBI
Celera1392,394,917 - 92,447,334 (-)NCBICelera
Cytogenetic Map13q26NCBI
NVL
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381224,227,345 - 224,330,172 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1224,227,334 - 224,330,189 (-)EnsemblGRCh38hg38GRCh38
GRCh371224,415,047 - 224,517,874 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361222,481,659 - 222,584,495 (-)NCBINCBI36hg18NCBI36
Build 341220,721,771 - 220,824,607NCBI
Celera1197,605,972 - 197,708,808 (-)NCBI
Cytogenetic Map1q42.11NCBI
HuRef1194,934,993 - 195,038,171 (-)NCBIHuRef
CHM1_11225,687,528 - 225,790,385 (-)NCBICHM1_1
T2T-CHM13v2.01223,416,266 - 223,519,053 (-)NCBI
Nvl
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391180,914,703 - 180,974,557 (-)NCBIGRCm39mm39
GRCm39 Ensembl1180,914,703 - 180,971,769 (-)Ensembl
GRCm381181,087,138 - 181,144,214 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1181,087,138 - 181,144,204 (-)EnsemblGRCm38mm10GRCm38
MGSCv371183,023,554 - 183,074,288 (-)NCBIGRCm37mm9NCBIm37
MGSCv361182,930,098 - 182,980,832 (-)NCBImm8
Celera1188,160,290 - 188,211,164 (-)NCBICelera
Cytogenetic Map1H4NCBI
Nvl
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555201,011,621 - 1,062,286 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555201,010,966 - 1,069,176 (+)NCBIChiLan1.0ChiLan1.0
NVL
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11204,704,095 - 204,807,027 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1204,704,371 - 204,806,959 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01199,695,388 - 199,798,080 (-)NCBIMhudiblu_PPA_v0panPan3
NVL
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1740,041,692 - 40,131,984 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl740,041,394 - 40,131,823 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha739,523,642 - 39,614,138 (+)NCBI
ROS_Cfam_1.0739,876,221 - 39,966,969 (+)NCBI
ROS_Cfam_1.0 Ensembl739,876,247 - 39,966,968 (+)Ensembl
UMICH_Zoey_3.1739,717,305 - 39,807,555 (+)NCBI
UNSW_CanFamBas_1.0739,724,584 - 39,815,053 (+)NCBI
UU_Cfam_GSD_1.0739,993,455 - 40,083,964 (+)NCBI
Nvl
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934453,365,252 - 53,472,551 (+)NCBI
SpeTri2.0NW_0049365261,274,760 - 1,381,997 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NVL
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1012,588,135 - 12,670,625 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11012,564,891 - 12,670,641 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
NVL
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1255,455,812 - 5,555,666 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl255,455,646 - 5,556,770 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660555,633,241 - 5,737,550 (+)NCBIVero_WHO_p1.0
Nvl
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248355,913,699 - 5,970,503 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046248355,896,014 - 5,977,581 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
BE106505  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21392,856,117 - 92,856,270 (+)MAPPERmRatBN7.2
Rnor_6.01399,421,865 - 99,422,017NCBIRnor6.0
Rnor_6.01399,412,494 - 99,412,646NCBIRnor6.0
Rnor_5.013104,417,555 - 104,417,707UniSTSRnor5.0
Rnor_5.013104,409,513 - 104,409,665UniSTSRnor5.0
RGSC_v3.41396,865,227 - 96,865,379UniSTSRGSC3.4
Celera1392,397,385 - 92,397,537UniSTS
RH 3.4 Map13631.1UniSTS
Cytogenetic Map13q26UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)131101056920Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)138897350101631289Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131101056920Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1365103704106807694Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1365103704106807694Rat
2293341Glom15Glomerulus QTL 159.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1374862117101339893Rat
4889606Gluco63Glucose level QTL 632.860.003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1380753256106807694Rat
8655959Pur32Proteinuria QTL 328.4total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)137402391897213863Rat
1641901Alcrsp6Alcohol response QTL 6response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)135236217197362171Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1330395351101056920Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1320605871101339738Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131101056920Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1356056920101056920Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133124133193395974Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1361825626106807694Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:200
Count of miRNA genes:147
Interacting mature miRNAs:158
Transcripts:ENSRNOT00000004927
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 8 25 12 18 12 57 18 39 9
Low 1 35 32 29 1 29 8 11 17 17 2 2 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000004927   ⟹   ENSRNOP00000004927
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1392,853,650 - 92,906,049 (-)Ensembl
Rnor_6.0 Ensembl1399,410,026 - 99,468,778 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000086888   ⟹   ENSRNOP00000070402
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1392,854,943 - 92,904,215 (-)Ensembl
Rnor_6.0 Ensembl1399,414,193 - 99,468,775 (-)Ensembl
RefSeq Acc Id: NM_001105980   ⟹   NP_001099450
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21392,853,650 - 92,906,049 (-)NCBI
Rnor_6.01399,410,026 - 99,468,778 (-)NCBI
Rnor_5.013104,407,045 - 104,465,204 (-)NCBI
RGSC_v3.41396,862,759 - 96,917,215 (-)RGD
Celera1392,394,917 - 92,447,334 (-)RGD
Sequence:
RefSeq Acc Id: XM_006250367   ⟹   XP_006250429
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21392,851,023 - 92,906,747 (-)NCBI
Rnor_6.01399,410,034 - 99,468,783 (-)NCBI
Rnor_5.013104,407,045 - 104,465,204 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006250370   ⟹   XP_006250432
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21392,851,023 - 92,905,932 (-)NCBI
Rnor_6.01399,410,034 - 99,459,448 (-)NCBI
Rnor_5.013104,407,045 - 104,465,204 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006250372   ⟹   XP_006250434
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21392,851,023 - 92,905,931 (-)NCBI
Rnor_6.01399,410,034 - 99,461,895 (-)NCBI
Rnor_5.013104,407,045 - 104,465,204 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017598728   ⟹   XP_017454217
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21392,851,023 - 92,905,932 (-)NCBI
Rnor_6.01399,410,034 - 99,466,890 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039090561   ⟹   XP_038946489
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21392,856,073 - 92,906,747 (-)NCBI
RefSeq Acc Id: XM_039090562   ⟹   XP_038946490
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21392,851,023 - 92,896,718 (-)NCBI
RefSeq Acc Id: XR_005492226
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21392,869,803 - 92,906,749 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_001099450   ⟸   NM_001105980
- UniProtKB: D3ZTY9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006250429   ⟸   XM_006250367
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006250434   ⟸   XM_006250372
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_006250432   ⟸   XM_006250370
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_017454217   ⟸   XM_017598728
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSRNOP00000004927   ⟸   ENSRNOT00000004927
RefSeq Acc Id: ENSRNOP00000070402   ⟸   ENSRNOT00000086888
RefSeq Acc Id: XP_038946490   ⟸   XM_039090562
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038946489   ⟸   XM_039090561
- Peptide Label: isoform X1
Protein Domains
AAA

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZTY9-F1-model_v2 AlphaFold D3ZTY9 1-855 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699071
Promoter ID:EPDNEW_R9592
Type:initiation region
Name:Nvl_1
Description:nuclear VCP-like
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01399,468,741 - 99,468,801EPDNEW

Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
Damaging Variants


Assembly: Rnor_6.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
13 99450248 99450249 G C snv F344/NCrl (RGD)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311270 AgrOrtholog
BioCyc Gene G2FUF-17099 BioCyc
Ensembl Genes ENSRNOG00000003629 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000004927 ENTREZGENE
  ENSRNOP00000004927.4 UniProtKB/TrEMBL
  ENSRNOP00000070402.2 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000004927 ENTREZGENE
  ENSRNOT00000004927.7 UniProtKB/TrEMBL
  ENSRNOT00000086888.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.2010 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
InterPro AAA_lid_3 UniProtKB/TrEMBL
  ATPase_AAA+_core UniProtKB/TrEMBL
  ATPase_AAA_core UniProtKB/TrEMBL
  ATPase_AAA_CS UniProtKB/TrEMBL
  NLV2_N_sf UniProtKB/TrEMBL
  NVL2_nucleolin-bd UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
KEGG Report rno:289323 UniProtKB/TrEMBL
NCBI Gene 289323 ENTREZGENE
Pfam AAA UniProtKB/TrEMBL
  AAA_lid_3 UniProtKB/TrEMBL
  Nucleolin_bd UniProtKB/TrEMBL
PhenoGen Nvl PhenoGen
PROSITE AAA UniProtKB/TrEMBL
SMART AAA UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A0G2JXU1_RAT UniProtKB/TrEMBL
  D3ZTY9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Nvl  nuclear VCP-like   Nvl_predicted  nuclear VCP-like (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Nvl_predicted  nuclear VCP-like (predicted)      Symbol and Name status set to approved 70820 APPROVED