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ONTOLOGY REPORT - ANNOTATIONS


Term:activated T cell proliferation
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Accession:GO:0050798 term browser browse the term
Definition:The expansion of a T cell population following activation by an antigenic stimulus.
Comment:Note that this term refers to the proliferation of previously activated T cells; it is to be used for gene products involved in T cell proliferation following an antigenic stimulus, including both proteins internal to the T cell and external factors, such as IL-2, which specifically promote proliferation of activated T cells.
Synonyms:exact_synonym: activated T lymphocyte proliferation;   proliferation of activated T cells


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activated T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase acts_upstream_of_or_within ISO (PMID:18025176) MGI PMID:18025176 NCBI chrNW_004624760:4,878,811...5,032,719
Ensembl chrNW_004624760:4,878,556...5,031,491
JBrowse link
G Cadm1 cell adhesion molecule 1 NOT|involved_in ISO (PMID:15811952) UniProt PMID:15811952 NCBI chrNW_004624784:10,595,876...10,933,024
Ensembl chrNW_004624784:10,591,824...10,932,981
JBrowse link
G Crtam cytotoxic and regulatory T cell molecule NOT|involved_in ISO (PMID:15811952) HGNC-UCL PMID:15811952 NCBI chrNW_004624880:2,229,201...2,240,068 JBrowse link
G Ephb6 EPH receptor B6 acts_upstream_of_or_within ISO (PMID:15599401) MGI PMID:15599401 NCBI chrNW_004624800:12,069,977...12,076,992
Ensembl chrNW_004624800:12,069,908...12,074,669
JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase acts_upstream_of_or_within ISO (PMID:1516132) MGI PMID:1516132 NCBI chrNW_004624933:248,298...456,933
Ensembl chrNW_004624933:389,627...456,520
JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial involved_in
acts_upstream_of
IEA
ISO
(PMID:18971390) Ensembl
MGI
PMID:18971390 GO_REF:0000107 NCBI chrNW_004624737:34,198,773...34,268,815
Ensembl chrNW_004624737:34,198,518...34,265,192
JBrowse link
G Il2 interleukin 2 acts_upstream_of ISO (PMID:10485657), (PMID:7584142)
(PMID:1830926)
MGI PMID:1830926 PMID:7584142 PMID:10485657 NCBI chrNW_004624777:2,885,537...2,890,453
Ensembl chrNW_004624777:2,885,535...2,890,453
JBrowse link
G Il2ra interleukin 2 receptor subunit alpha acts_upstream_of ISO (PMID:7584142) MGI PMID:7584142 NCBI chrNW_004624775:927,337...991,062
Ensembl chrNW_004624775:924,648...942,354
JBrowse link
G Il4 interleukin 4 acts_upstream_of ISO (PMID:10485657), (PMID:9841920) MGI PMID:9841920 PMID:10485657 NCBI chrNW_004624733:39,412,800...39,420,079 JBrowse link
G Itgal integrin subunit alpha L acts_upstream_of_or_within ISO (PMID:15210787) MGI PMID:15210787 NCBI chrNW_004624782:13,635,217...13,671,401
Ensembl chrNW_004624782:13,640,996...13,669,541
JBrowse link
G Itgam integrin subunit alpha M acts_upstream_of_or_within ISO (PMID:15210787) MGI PMID:15210787 NCBI chrNW_004624782:14,316,505...14,367,841
Ensembl chrNW_004624782:14,318,499...14,367,922
JBrowse link
G Itgax integrin subunit alpha X NOT|acts_upstream_of_or_within ISO (PMID:15210787) MGI PMID:15210787 NCBI chrNW_004624782:14,380,234...14,397,552
Ensembl chrNW_004624782:14,380,399...14,395,916
JBrowse link
G Itgb2 integrin subunit beta 2 acts_upstream_of_or_within ISO (PMID:15210787) MGI PMID:15210787 NCBI chrNW_004624745:30,452,576...30,479,036
Ensembl chrNW_004624745:30,452,576...30,470,611
JBrowse link
G Satb1 SATB homeobox 1 acts_upstream_of_or_within ISO (PMID:15814699) MGI PMID:15814699 NCBI chrNW_004624821:3,723,609...3,820,921
Ensembl chrNW_004624821:3,726,355...3,800,497
JBrowse link
negative regulation of activated T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg1 arginase 1 involved_in ISO (PMID:19360123) UniProt PMID:19360123 NCBI chrNW_004624753:5,737,720...5,749,313
Ensembl chrNW_004624753:5,737,237...5,752,966
JBrowse link
G Cd274 CD274 molecule involved_in ISO (PMID:12538684)
(PMID:17489864)
UniProt
AgBase
PMID:12538684 PMID:17489864 NCBI chrNW_004624736:9,991,851...10,017,047
Ensembl chrNW_004624736:9,996,156...10,013,814
JBrowse link
G Crtam cytotoxic and regulatory T cell molecule involved_in ISO (PMID:18329370) UniProt PMID:18329370 NCBI chrNW_004624880:2,229,201...2,240,068 JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:18077788) Ensembl
MGI
PMID:18077788 GO_REF:0000107 NCBI chrNW_004624780:3,684,941...3,697,506
Ensembl chrNW_004624780:3,685,069...3,697,474
JBrowse link
G Laptm5 lysosomal protein transmembrane 5 involved_in ISO (PMID:18619870) ARUK-UCL PMID:18619870 NCBI chrNW_004624764:14,208,144...14,277,208
Ensembl chrNW_004624764:14,207,094...14,228,135
JBrowse link
G Lgals9 galectin 9 involved_in ISO (PMID:23817958) UniProt PMID:23817958 NCBI chrNW_004624786:478,048...491,086 JBrowse link
G Lrrc32 leucine rich repeat containing 32 acts_upstream_of_or_within ISO (PMID:18628982) MGI PMID:18628982 NCBI chrNW_004624817:497,415...510,061
Ensembl chrNW_004624817:497,372...510,580
JBrowse link
G Pdcd1lg2 programmed cell death 1 ligand 2 involved_in ISO (PMID:12538684) UniProt PMID:12538684 NCBI chrNW_004624736:10,049,428...10,056,849 JBrowse link
G Prkar1a protein kinase cAMP-dependent type I regulatory subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624870:3,552,608...3,575,461
Ensembl chrNW_004624870:3,552,745...3,574,880
JBrowse link
G Prnp prion protein (Kanno blood group) involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624741:5,785,139...5,802,162
Ensembl chrNW_004624741:5,785,158...5,802,162
JBrowse link
G Rc3h1 ring finger and CCCH-type domains 1 involved_in ISO (PMID:18172933) BHF-UCL PMID:18172933 NCBI chrNW_004624771:7,837,547...7,948,217 JBrowse link
G Scrib scribble planar cell polarity protein involved_in ISO (PMID:18329370) UniProt PMID:18329370 NCBI chrNW_004624735:12,997,358...13,018,765
Ensembl chrNW_004624735:12,997,408...13,018,533
JBrowse link
positive regulation of activated T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end-product specific receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624754:24,138,086...24,140,900 JBrowse link
G Cd24 CD24 molecule involved_in ISS UniProt GO_REF:0000024 NCBI chrNW_004624780:15,287,426...15,292,292
Ensembl chrNW_004624780:15,287,433...15,292,292
JBrowse link
G Cd86 CD86 molecule ISO RGD PMID:9237108 RGD:632472 NCBI chrNW_004624912:350,201...432,410
Ensembl chrNW_004624912:350,157...426,712
JBrowse link
G Fadd Fas associated via death domain involved_in IEA
ISS
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chrNW_004624767:17,050,929...17,059,648
Ensembl chrNW_004624767:17,055,509...17,059,705
JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:18971390) Ensembl
MGI
PMID:18971390 GO_REF:0000107 NCBI chrNW_004624737:34,198,773...34,268,815
Ensembl chrNW_004624737:34,198,518...34,265,192
JBrowse link
G Hhla2 HHLA2 member of B7 family involved_in ISO (PMID:23784006) UniProt PMID:23784006 NCBI chrNW_004624731:41,153,064...41,251,779
Ensembl chrNW_004624731:41,151,649...41,248,520
JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO (PMID:15944249) UniProt PMID:15944249 NCBI chrNW_004624776:7,858,400...7,862,716
Ensembl chrNW_004624776:7,793,259...7,863,184
JBrowse link
G Igf1 insulin like growth factor 1 involved_in ISO (PMID:15694994) BHF-UCL PMID:15694994 NCBI chrNW_004624750:5,881,065...5,954,799
Ensembl chrNW_004624750:5,881,091...5,952,300
JBrowse link
G Igf2 insulin like growth factor 2 involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624767:14,969,977...14,997,577
Ensembl chrNW_004624767:14,969,866...14,979,026
JBrowse link
G Igfbp2 insulin like growth factor binding protein 2 involved_in ISO (PMID:15694994) BHF-UCL PMID:15694994 NCBI chrNW_004624823:8,460,968...8,486,495
Ensembl chrNW_004624823:8,460,553...8,486,495
JBrowse link
G Il12b interleukin 12B involved_in ISO (PMID:11114383), (PMID:1674604) UniProt PMID:1674604 PMID:11114383 NCBI chrNW_004624733:30,146,050...30,156,144
Ensembl chrNW_004624733:30,146,050...30,154,589
JBrowse link
G Il12rb1 interleukin 12 receptor subunit beta 1 involved_in ISO (PMID:11114383) BHF-UCL PMID:11114383 NCBI chrNW_004624908:1,472,059...1,481,423 JBrowse link
G Il18 interleukin 18 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624784:7,294,286...7,312,959
Ensembl chrNW_004624784:7,294,183...7,304,687
JBrowse link
G Il2 interleukin 2 acts_upstream_of_or_within ISO (PMID:10072077), (PMID:1830926)
(PMID:1830926)
(PMID:10485657), (PMID:7584142)
MGI PMID:1830926 PMID:7584142 PMID:10072077 PMID:10485657 NCBI chrNW_004624777:2,885,537...2,890,453
Ensembl chrNW_004624777:2,885,535...2,890,453
JBrowse link
G Il23a interleukin 23 subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624802:11,662,851...11,664,444
Ensembl chrNW_004624802:11,662,753...11,665,418
JBrowse link
G Il2ra interleukin 2 receptor subunit alpha acts_upstream_of_or_within ISO (PMID:7584142) MGI PMID:7584142 NCBI chrNW_004624775:927,337...991,062
Ensembl chrNW_004624775:924,648...942,354
JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (PMID:10485657), (PMID:9841920) MGI PMID:9841920 PMID:10485657 NCBI chrNW_004624733:39,412,800...39,420,079 JBrowse link
G Jak3 Janus kinase 3 ISO RGD PMID:11781254 RGD:1600262 NCBI chrNW_004624908:1,371,595...1,383,879
Ensembl chrNW_004624908:1,371,595...1,383,879
JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624830:6,318,352...6,584,232
Ensembl chrNW_004624830:6,317,968...6,581,892
JBrowse link
G Pycard PYD and CARD domain containing involved_in ISO (PMID:21892172) UniProt PMID:21892172 NCBI chrNW_004624782:14,247,333...14,249,861
Ensembl chrNW_004624782:14,247,864...14,249,000
JBrowse link
G Rps3 ribosomal protein S3 involved_in ISO (PMID:18045535) CAFA PMID:18045535 NCBI chrNW_004624817:1,710,768...1,715,923
Ensembl chrNW_004624817:1,710,768...1,716,224
JBrowse link
G Slamf1 signaling lymphocytic activation molecule family member 1 involved_in ISO (PMID:9126961) UniProt PMID:9126961 NCBI chrNW_004624794:627,906...661,257 JBrowse link
G Tmigd2 transmembrane and immunoglobulin domain containing 2 involved_in ISO (PMID:23784006) UniProt PMID:23784006 NCBI chrNW_004624828:5,363,038...5,367,301 JBrowse link
G Tnfsf4 TNF superfamily member 4 ISO RGD PMID:9790919 RGD:634509 NCBI chrNW_004624771:8,580,489...8,599,735 JBrowse link
G Tnfsf9 TNF superfamily member 9 involved_in ISO
IEA
RGD
TreeGrafter
PMID:19187795 GO_REF:0000118 RGD:2317344 NCBI chrNW_004624828:3,615,860...3,623,377 JBrowse link
regulation of activated T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd274 CD274 molecule NOT|involved_in ISO (PMID:24187568), (PMID:25310899) UniProt PMID:24187568 PMID:25310899 NCBI chrNW_004624736:9,991,851...10,017,047
Ensembl chrNW_004624736:9,996,156...10,013,814
JBrowse link
G Icam1 intercellular adhesion molecule 1 NOT|involved_in ISO (PMID:25310899) UniProt PMID:25310899 NCBI chrNW_004624828:2,432,584...2,451,997
Ensembl chrNW_004624828:2,432,550...2,453,071
JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 NOT|involved_in ISO (PMID:25310899) UniProt PMID:25310899 NCBI chrNW_004624780:3,684,941...3,697,506
Ensembl chrNW_004624780:3,685,069...3,697,474
JBrowse link
G Ripk3 receptor interacting serine/threonine kinase 3 involved_in ISO (PMID:21876153) UniProt PMID:21876153 NCBI chrNW_004624820:8,165,546...8,169,172 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17640
    immune system process 2276
      leukocyte activation 921
        lymphocyte activation 749
          lymphocyte proliferation 308
            T cell proliferation 226
              activated T cell proliferation 48
                negative regulation of activated T cell proliferation 12
                positive regulation of activated T cell proliferation 25
                regulation of activated T cell proliferation + 39
Path 2
Term Annotations click to browse term
  biological_process 17640
    cellular process 17222
      cell activation 1071
        leukocyte activation 921
          lymphocyte activation 749
            T cell activation 529
              T cell proliferation 226
                activated T cell proliferation 48
                  negative regulation of activated T cell proliferation 12
                  positive regulation of activated T cell proliferation 25
                  regulation of activated T cell proliferation + 39
paths to the root