Il2ra (interleukin 2 receptor subunit alpha) - Rat Genome Database

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Gene: Il2ra (interleukin 2 receptor subunit alpha) Heterocephalus glaber
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Symbol: Il2ra
Name: interleukin 2 receptor subunit alpha
RGD ID: 18924914
Description: ENCODES a protein that exhibits interleukin-2 receptor activity (ortholog); INVOLVED IN activated T cell proliferation (ortholog); activation-induced cell death of T cells (ortholog); inflammatory response to antigenic stimulus (ortholog); PARTICIPATES IN interleukin-12 signaling pathway; interleukin-2 signaling pathway; ASSOCIATED WITH allergic contact dermatitis (ortholog); alopecia areata (ortholog); asthma (ortholog); FOUND IN cell surface (ortholog); external side of plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: interleukin-2 receptor subunit alpha
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624775924,648 - 942,354 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624775927,337 - 991,062 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Il2ra
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624775924,648 - 942,354 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624775927,337 - 991,062 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
IL2RA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38106,010,689 - 6,062,367 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl106,010,689 - 6,062,370 (-)EnsemblGRCh38hg38GRCh38
GRCh37106,052,652 - 6,104,330 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36106,093,512 - 6,144,278 (-)NCBINCBI36Build 36hg18NCBI36
Build 34106,093,511 - 6,144,278NCBI
Celera105,982,579 - 6,033,743 (-)NCBICelera
Cytogenetic Map10p15.1NCBI
HuRef105,979,490 - 6,030,662 (-)NCBIHuRef
CHM1_1106,052,649 - 6,103,793 (-)NCBICHM1_1
T2T-CHM13v2.0106,011,401 - 6,062,560 (-)NCBIT2T-CHM13v2.0
Il2ra
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39211,647,603 - 11,698,005 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl211,647,618 - 11,698,004 (+)EnsemblGRCm39 Ensembl
GRCm38211,642,792 - 11,693,194 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl211,642,807 - 11,693,193 (+)EnsemblGRCm38mm10GRCm38
MGSCv37211,564,419 - 11,614,821 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36211,560,703 - 11,611,044 (+)NCBIMGSCv36mm8
Celera211,560,200 - 11,610,847 (+)NCBICelera
Cytogenetic Map2A1NCBI
cM Map28.91NCBI
Il2ra
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81771,759,802 - 71,808,475 (-)NCBIGRCr8
mRatBN7.21766,849,974 - 66,898,665 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1766,849,974 - 66,898,697 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1770,337,084 - 70,384,350 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01774,165,907 - 74,213,174 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01768,208,899 - 68,256,163 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01770,500,672 - 70,547,929 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1770,499,083 - 70,548,071 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01772,204,467 - 72,250,556 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41778,050,491 - 78,097,802 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11778,061,323 - 78,108,635 (-)NCBI
Celera1766,355,852 - 66,402,955 (-)NCBICelera
RH 3.4 Map17636.4RGD
Cytogenetic Map17q12.2NCBI
Il2ra
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542122,641,511 - 22,694,913 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542122,642,004 - 22,694,729 (-)NCBIChiLan1.0ChiLan1.0
IL2RA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2818,563,961 - 18,618,076 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11018,569,284 - 18,623,389 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0106,053,549 - 6,103,863 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1106,037,664 - 6,086,018 (-)NCBIpanpan1.1PanPan1.1panPan2
IL2RA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1229,892,130 - 29,948,926 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl229,894,125 - 29,944,643 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha226,924,836 - 26,975,354 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0230,275,012 - 30,330,188 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl230,275,175 - 30,327,642 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1227,372,288 - 27,422,786 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0228,208,376 - 28,259,290 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0228,928,272 - 28,977,130 (+)NCBIUU_Cfam_GSD_1.0
Il2ra
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934432,349,142 - 32,390,487 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364848,544,062 - 8,555,332 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364848,514,333 - 8,555,392 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IL2RA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1064,948,563 - 65,001,142 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11064,948,149 - 65,001,320 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21071,153,916 - 71,162,729 (-)NCBISscrofa10.2Sscrofa10.2susScr3
IL2RA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.196,134,961 - 6,187,731 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl96,141,430 - 6,149,447 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605111,438,032 - 11,490,878 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000013430   ⟹   ENSHGLP00000013291
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_004624775924,648 - 942,354 (-)Ensembl
RefSeq Acc Id: XM_021266443   ⟹   XP_021122102
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624775927,337 - 991,062 (-)NCBI
Protein Sequences
Protein RefSeqs XP_021122102 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_021122102   ⟸   XM_021266443
- UniProtKB: A0AAX6TI62 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000013291   ⟸   ENSHGLT00000013430


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000009500 Ensembl
Gene3D-CATH 2.20.28.230 UniProtKB/TrEMBL
  Complement Module, domain 1 UniProtKB/TrEMBL
InterPro IL-2_rcpt_alpha UniProtKB/TrEMBL
  Sushi/SCR/CCP_sf UniProtKB/TrEMBL
  Sushi_SCR_CCP_dom UniProtKB/TrEMBL
NCBI Gene Il2ra ENTREZGENE
PANTHER INTERLEUKIN-2 RECEPTOR ALPHA CHAIN UniProtKB/TrEMBL
  INTERLEUKIN-2 RECEPTOR SUBUNIT ALPHA UniProtKB/TrEMBL
PROSITE SUSHI UniProtKB/TrEMBL
SMART CCP UniProtKB/TrEMBL
Superfamily-SCOP Complement control module/SCR domain UniProtKB/TrEMBL
UniProt A0AAX6TI62 ENTREZGENE, UniProtKB/TrEMBL