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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of axon regeneration
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Accession:GO:0048679 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of axon regeneration.

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regulation of axon regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM17 ADAM metallopeptidase domain 17 acts_upstream_of_or_within ISO (PMID:26651291) MGI PMID:26651291 NCBI chr14:98,092,093...98,157,657
Ensembl chr14:98,092,044...98,157,217 		JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase acts_upstream_of_or_within ISO (PMID:24733831) MGI PMID:24733831 NCBI chr21:109,495,525...109,690,261 JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase involved_in IEA Ensembl GO_REF:0000107 Ensembl chr21:109,545,491...109,690,195 JBrowse link
G KLF4 KLF transcription factor 4 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:24129709) MGI
Ensembl		 PMID:24129709 GO_REF:0000107 NCBI chr12:32,045,690...32,050,531
Ensembl chr12:32,045,609...32,050,703 		JBrowse link
G LRIG2 leucine rich repeats and immunoglobulin like domains 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:26651291) Ensembl
MGI		 PMID:26651291 GO_REF:0000107 NCBI chr20:20,523,713...20,575,577
Ensembl chr20:20,524,352...20,574,224 		JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24733831) Ensembl
MGI		 PMID:24733831 GO_REF:0000107 NCBI chr26:17,059,122...17,168,787
Ensembl chr26:17,060,054...17,168,782 		JBrowse link
G MAP2K2 mitogen-activated protein kinase kinase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24733831) Ensembl
MGI		 PMID:24733831 GO_REF:0000107 NCBI chr 6:3,848,441...3,881,367
Ensembl chr 6:3,848,401...3,881,412 		JBrowse link
G NEO1 neogenin 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:26651291) MGI
Ensembl		 PMID:26651291 GO_REF:0000107 NCBI chr26:10,173,707...10,427,732
Ensembl chr26:10,176,215...10,427,675 		JBrowse link
G PTEN phosphatase and tensin homolog acts_upstream_of_or_within ISO (PMID:24733831) MGI PMID:24733831 NCBI chr 9:81,308,058...81,412,386
Ensembl chr 9:81,309,099...81,409,146 		JBrowse link
G PTPRF protein tyrosine phosphatase receptor type F involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21976490) Ensembl
MGI		 PMID:21976490 GO_REF:0000107 NCBI chr20:89,192,426...89,284,989
Ensembl chr20:89,191,660...89,284,970 		JBrowse link
G STK24 serine/threonine kinase 24 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:77,104,417...77,231,402
Ensembl chr 3:77,105,429...77,196,934 		JBrowse link
negative regulation of axon extension involved in regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KIAA0319 KIAA0319 ortholog acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:28334068) MGI
Ensembl		 PMID:28334068 GO_REF:0000107 NCBI chr17:47,603,506...47,702,154
Ensembl chr17:47,603,705...47,696,302 		JBrowse link
G TNR tenascin R involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16870730) Ensembl
MGI		 PMID:16870730 GO_REF:0000107 NCBI chr25:53,526,477...53,942,278 JBrowse link
negative regulation of axon regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CERS2 ceramide synthase 2 involved_in ISO PMID:22393241 BHF-UCL PMID:22393241 RGD:11041067
G EPHA4 EPH receptor A4 involved_in
NOT		 ISO
IEA		 RGD
Ensembl		 PMID:17418490 PMID:17970742 GO_REF:0000107 RGD:5688750 RGD:5688782 NCBI chr10:107,344,442...107,501,375
Ensembl chr10:107,352,530...107,499,788 		JBrowse link
G FIGNL2 fidgetin like 2 involved_in ISO PMID:33872220 UniProt PMID:33872220 RGD:401901234 NCBI chr11:48,010,951...48,021,889 JBrowse link
G INPP5F inositol polyphosphate-5-phosphatase F involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:112,517,524...112,621,452
Ensembl chr 9:112,517,724...112,621,685 		JBrowse link
G KREMEN1 kringle containing transmembrane protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:11,943,787...12,056,706
Ensembl chr19:11,943,835...12,014,759 		JBrowse link
G LRIG2 leucine rich repeats and immunoglobulin like domains 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:26651291) Ensembl
MGI		 PMID:26651291 GO_REF:0000107 NCBI chr20:20,523,713...20,575,577
Ensembl chr20:20,524,352...20,574,224 		JBrowse link
G NEO1 neogenin 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:26651291) MGI
Ensembl		 PMID:26651291 GO_REF:0000107 NCBI chr26:10,173,707...10,427,732
Ensembl chr26:10,176,215...10,427,675 		JBrowse link
G PTEN phosphatase and tensin homolog involved_in ISO (PMID:26203138) ParkinsonsUK-UCL PMID:26203138 NCBI chr 9:81,308,058...81,412,386
Ensembl chr 9:81,309,099...81,409,146 		JBrowse link
G PTPRS protein tyrosine phosphatase receptor type S involved_in ISO (PMID:19780196), (PMID:22406547) UniProt PMID:19780196 PMID:22406547 NCBI chr 6:4,880,942...5,019,654
Ensembl chr 6:4,882,223...4,964,919 		JBrowse link
G RGMA repulsive guidance molecule BMP co-receptor a ISO RGD PMID:16585268 RGD:9850138 NCBI chr29:11,592,929...11,638,955
Ensembl chr29:11,592,604...11,638,860 		JBrowse link
G RTN4R reticulon 4 receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:5,469,854...5,497,858 JBrowse link
G RTN4RL1 reticulon 4 receptor like 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:1,576,264...1,665,130
Ensembl chr16:1,576,249...1,664,947 		JBrowse link
G XYLT1 xylosyltransferase 1 ISO RGD PMID:18765417 RGD:2313145 NCBI chr 5:16,197,982...16,566,893 JBrowse link
negative regulation of collateral sprouting of intact axon in response to injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SPP1 secreted phosphoprotein 1 ISO RGD PMID:15625076 RGD:1581125 NCBI chr 7:36,337,165...36,344,927
Ensembl chr 7:36,338,386...36,344,407 		JBrowse link
negative regulation of optical nerve axon regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RTCA RNA 3'-terminal phosphate cyclase involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:33,047,610...33,072,478
Ensembl chr20:33,047,476...33,073,179 		JBrowse link
positive regulation of axon extension involved in regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LRP1 LDL receptor related protein 1 ISO RGD PMID:23867460 RGD:13800520 NCBI chr11:53,039,147...53,125,041
Ensembl chr11:53,039,364...53,125,776 		JBrowse link
G NTRK3 neurotrophic receptor tyrosine kinase 3 acts_upstream_of_or_within ISO (PMID:16142215) MGI PMID:16142215 NCBI chr29:6,441,824...6,831,029
Ensembl chr29:6,447,256...6,830,526 		JBrowse link
positive regulation of axon regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BDNF brain derived neurotrophic factor ISO RGD PMID:24873730 RGD:405878058 NCBI chr 1:37,386,825...37,451,380
Ensembl chr 1:37,449,593...37,450,336 		JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase acts_upstream_of_or_within ISO (PMID:24733831) MGI PMID:24733831 NCBI chr21:109,495,525...109,690,261 JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase involved_in IEA Ensembl GO_REF:0000107 Ensembl chr21:109,545,491...109,690,195 JBrowse link
G CNTF ciliary neurotrophic factor involved_in ISO
IEA		 RGD
TreeGrafter		 PMID:15574731 GO_REF:0000118 RGD:1626128 NCBI chr 1:14,724,562...14,730,698
Ensembl chr 1:14,728,383...14,730,150 		JBrowse link
G FKBP1B FKBP prolyl isomerase 1B ISO RGD PMID:9512405 RGD:7205517 NCBI chr14:83,606,511...83,620,289
Ensembl chr14:83,606,454...83,620,205 		JBrowse link
G FLNA filamin A involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:128,657,580...128,683,812
Ensembl chr  X:128,657,393...128,680,531 		JBrowse link
G GRN granulin precursor involved_in ISO (PMID:28453791) UniProt PMID:28453791 NCBI chr16:62,037,344...62,045,765
Ensembl chr16:62,036,412...62,045,614 		JBrowse link
G IGF1R insulin like growth factor 1 receptor ISO RGD PMID:23349896 RGD:10046026 NCBI chr29:17,212,206...17,534,036
Ensembl chr29:17,459,404...17,526,930 		JBrowse link
G MIF macrophage migration inhibitory factor ISO RGD PMID:12456989 RGD:1642004 NCBI chr19:7,000,837...7,001,700
Ensembl chr19:7,000,793...7,001,757 		JBrowse link
G NDEL1 nudE neurodevelopment protein 1 like 1 ISO RGD PMID:18431495 RGD:2306515 NCBI chr16:7,797,858...7,831,211 JBrowse link
G NRG1 neuregulin 1 ISO RGD PMID:20957456 RGD:10449012 NCBI chr 8:29,745,984...30,862,140
Ensembl chr 8:30,635,803...30,856,487 		JBrowse link
G PTN pleiotrophin involved_in ISO PMID:27671118 UniProt PMID:27671118 RGD:14397577 NCBI chr21:105,911,171...106,027,108
Ensembl chr21:105,911,120...106,027,215 		JBrowse link
G SCARF1 scavenger receptor class F member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:1,303,484...1,317,010
Ensembl chr16:1,304,378...1,316,678 		JBrowse link
G STK24 serine/threonine kinase 24 ISO RGD PMID:19855390 RGD:2317003 NCBI chr 3:77,104,417...77,231,402
Ensembl chr 3:77,105,429...77,196,934 		JBrowse link
positive regulation of collateral sprouting of injured axon term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LRP1 LDL receptor related protein 1 ISO RGD PMID:23867460 RGD:13800520 NCBI chr11:53,039,147...53,125,041
Ensembl chr11:53,039,364...53,125,776 		JBrowse link
positive regulation of sprouting of injured axon term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PUM2 pumilio RNA binding family member 2 ISO RGD PMID:31606248 RGD:242905203 NCBI chr14:87,368,288...87,473,282
Ensembl chr14:87,391,219...87,474,676 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19829
    regulation of biological process 11764
      regulation of response to stimulus 4190
        regulation of response to external stimulus 1173
          regulation of axon regeneration 39
            negative regulation of axon regeneration + 17
            positive regulation of axon regeneration + 17
            regulation of collateral sprouting of intact axon in response to injury + 1
            regulation of optical nerve axon regeneration + 1
Path 2
Term Annotations click to browse term
  biological_process 19829
    developmental process 6858
      anatomical structure development 6432
        multicellular organism development 5173
          system development 4482
            nervous system development 2806
              neurogenesis 2070
                generation of neurons 1793
                  neuron differentiation 1709
                    neuron development 1399
                      neuron projection development 1231
                        neuron projection regeneration 88
                          axon regeneration 75
                            regulation of axon regeneration 39
                              negative regulation of axon regeneration + 17
                              positive regulation of axon regeneration + 17
                              regulation of collateral sprouting of intact axon in response to injury + 1
                              regulation of optical nerve axon regeneration + 1
paths to the root