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ONTOLOGY REPORT - ANNOTATIONS

Term:mRNA stabilization
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Accession:GO:0048255 term browser browse the term
Definition:Prevention of degradation of mRNA molecules. In the absence of compensating changes in other processes, the slowing of mRNA degradation can result in an overall increase in the population of active mRNA molecules.

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mRNA stabilization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apobec1 apolipoprotein B mRNA editing enzyme catalytic subunit 1 acts_upstream_of_or_within ISO (PMID:15480992) MGI PMID:15480992 NCBI chrNW_004624860:4,938,001...4,957,640
Ensembl chrNW_004624860:4,938,001...4,957,236 		JBrowse link
G Axin2 axin 2 involved_in ISO (PMID:17072303) BHF-UCL PMID:17072303 NCBI chrNW_004624870:2,803,743...2,832,489
Ensembl chrNW_004624870:2,800,873...2,832,626 		JBrowse link
G Cirbp cold inducible RNA binding protein involved_in ISO (PMID:11574538) UniProt PMID:11574538 NCBI chrNW_004624828:7,401,123...7,409,275
Ensembl chrNW_004624828:7,401,456...7,409,408 		JBrowse link
G Dicer1 dicer 1, ribonuclease III acts_upstream_of_or_within ISO (PMID:22844247) MGI PMID:22844247 NCBI chrNW_004624734:7,604,049...7,681,481
Ensembl chrNW_004624734:7,608,273...7,651,819 		JBrowse link
G E2f1 E2F transcription factor 1 involved_in ISO (PMID:15766563) BHF-UCL PMID:15766563 NCBI chrNW_004624842:5,602,432...5,612,951
Ensembl chrNW_004624842:5,602,432...5,612,951 		JBrowse link
G Eif4enif1 eukaryotic translation initiation factor 4E nuclear import factor 1 involved_in ISO (PMID:24335285), (PMID:32354837) UniProt PMID:24335285 PMID:32354837 NCBI chrNW_004624747:7,899,128...7,949,911
Ensembl chrNW_004624747:7,899,439...7,949,930 		JBrowse link
G Elavl1 ELAV like RNA binding protein 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:21613615)
(PMID:14976220), (PMID:21613615)		 MGI
Ensembl		 PMID:14976220 PMID:21613615 GO_REF:0000107 NCBI chrNW_004624828:913,001...948,826
Ensembl chrNW_004624828:914,141...948,831 		JBrowse link
G Fam76b family with sequence similarity 76 member B involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624735:40,626,450...40,646,360
Ensembl chrNW_004624735:40,626,364...40,646,474 		JBrowse link
G Fus FUS RNA binding protein acts_upstream_of_or_within ISO (PMID:27378374) MGI PMID:27378374 NCBI chrNW_004624782:14,211,294...14,223,698 JBrowse link
G Gdnf glial cell derived neurotrophic factor involved_in ISO (PMID:12358785) BHF-UCL PMID:12358785 NCBI chrNW_004624759:17,263,570...17,290,046
Ensembl chrNW_004624759:17,263,969...17,287,723 		JBrowse link
G Hnrnpu heterogeneous nuclear ribonucleoprotein U involved_in ISO (PMID:17174306) UniProt PMID:17174306 NCBI chrNW_004624771:14,756,088...14,766,106
Ensembl chrNW_004624771:14,756,100...14,765,832 		JBrowse link
G Ikbke inhibitor of nuclear factor kappa B kinase subunit epsilon involved_in ISO (PMID:21822257) MGI PMID:21822257 NCBI chrNW_004624807:4,913,734...4,934,096
Ensembl chrNW_004624807:4,913,742...4,933,267 		JBrowse link
G Larp1 La ribonucleoprotein 1, translational regulator involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004624733:34,504,259...34,593,223
Ensembl chrNW_004624733:34,507,618...34,560,901 		JBrowse link
G Mapkapk2 MAPK activated protein kinase 2 acts_upstream_of_or_within ISO (PMID:11741878) MGI PMID:11741878 NCBI chrNW_004624807:4,726,511...4,774,945
Ensembl chrNW_004624807:4,724,234...4,796,143 		JBrowse link
G Meioc meiosis specific with coiled-coil domain involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624795:527,562...554,337
Ensembl chrNW_004624795:529,913...550,012 		JBrowse link
G Mettl14 methyltransferase 14, N6-adenosine-methyltransferase non-catalytic subunit involved_in ISO (PMID:29290617) ARUK-UCL PMID:29290617 NCBI chrNW_004624867:5,508,847...5,533,395
Ensembl chrNW_004624867:5,508,886...5,533,395 		JBrowse link
G Mtor mechanistic target of rapamycin kinase ISO RGD PMID:21073857 RGD:10040969 NCBI chrNW_004624818:1,570,155...1,698,264
Ensembl chrNW_004624818:1,570,276...1,698,259 		JBrowse link
G Noct nocturnin involved_in ISO (PMID:22073225) UniProt PMID:22073225 NCBI chrNW_004624777:19,379,447...19,383,477 JBrowse link
G Nrde2 NRDE-2, necessary for RNA interference, domain containing involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624734:12,098,386...12,151,635
Ensembl chrNW_004624734:12,098,361...12,148,760 		JBrowse link
G Qki QKI, KH domain containing RNA binding involved_in ISO (PMID:32732889) RGD
UniProt		 PMID:16855020 PMID:32732889 RGD:10045995 NCBI chrNW_004624785:15,738,231...15,845,051
Ensembl chrNW_004624785:15,739,187...15,845,024 		JBrowse link
G Rbm10 RNA binding motif protein 10 ISO RGD PMID:19508861 RGD:151667451 NCBI chrNW_004624887:3,921,934...3,953,739
Ensembl chrNW_004624887:3,923,986...3,957,133 		JBrowse link
G Rbm24 RNA binding motif protein 24 involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624756:9,253,310...9,262,859
Ensembl chrNW_004624756:9,250,945...9,262,899 		JBrowse link
G Rbm46 RNA binding motif protein 46 acts_upstream_of_or_within ISO (PMID:25397698) MGI PMID:25397698 NCBI chrNW_004624848:3,482,539...3,532,577 JBrowse link
G Secisbp2 SECIS binding protein 2 acts_upstream_of_or_within ISO (PMID:27956496) MGI PMID:27956496 NCBI chrNW_004624765:23,246,342...23,296,071
Ensembl chrNW_004624765:23,247,135...23,296,465 		JBrowse link
G Slc11a1 solute carrier family 11 member 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:9009318) MGI
Ensembl		 PMID:9009318 GO_REF:0000107 NCBI chrNW_004624823:6,612,452...6,625,047
Ensembl chrNW_004624823:6,612,452...6,625,300 		JBrowse link
G Taf15 TATA-box binding protein associated factor 15 acts_upstream_of_or_within ISO (PMID:27378374) MGI PMID:27378374 NCBI chrNW_004624875:3,278,055...3,311,915 JBrowse link
G Tent5a terminal nucleotidyltransferase 5A involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624799:12,829,562...12,836,850
Ensembl chrNW_004624799:12,829,528...12,834,511 		JBrowse link
G Tent5b terminal nucleotidyltransferase 5B involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624764:10,964,925...10,976,330 JBrowse link
G Tent5c terminal nucleotidyltransferase 5C involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624772:13,348,302...13,378,095
Ensembl chrNW_004624772:13,348,369...13,366,076 		JBrowse link
G Tent5d terminal nucleotidyltransferase 5D involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624836:711,182...723,998
Ensembl chrNW_004624836:711,234...712,406 		JBrowse link
G Thrap3 thyroid hormone receptor associated protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624764:19,194,469...19,236,518
Ensembl chrNW_004624764:19,194,496...19,238,123 		JBrowse link
G Traf2 TNF receptor associated factor 2 involved_in ISO (PMID:21822258) MGI PMID:21822258 NCBI chrNW_004624760:952,574...973,511
Ensembl chrNW_004624760:952,574...965,661 		JBrowse link
G Traf3ip2 TRAF3 interacting protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624933:507,879...558,357
Ensembl chrNW_004624933:506,254...554,015 		JBrowse link
G Traf5 TNF receptor associated factor 5 involved_in ISO (PMID:21822258) MGI PMID:21822258 NCBI chrNW_004624807:878,275...921,683
Ensembl chrNW_004624807:878,665...898,558 		JBrowse link
G Vegfa vascular endothelial growth factor A ISO RGD PMID:12881220 RGD:1580563 NCBI chrNW_004624754:15,929,414...15,943,637 JBrowse link
G Vip vasoactive intestinal peptide involved_in ISS AgBase GO_REF:0000024 NCBI chrNW_004624785:5,466,429...5,487,763
Ensembl chrNW_004624785:5,468,563...5,488,143 		JBrowse link
G Ybx1 Y-box binding protein 1 involved_in ISO (PMID:31358969) UniProt PMID:31358969 NCBI chrNW_004624892:1,939,641...1,957,621
Ensembl chrNW_004624892:1,939,098...1,957,623 		JBrowse link
G Ybx2 Y-box binding protein 2 acts_upstream_of_or_within ISO (PMID:17035640) MGI PMID:17035640 NCBI chrNW_004624786:9,909,464...9,915,335
Ensembl chrNW_004624786:9,909,761...9,915,280 		JBrowse link
G Zar1 zygote arrest 1 involved_in ISO (PMID:36264786) UniProt PMID:36264786 NCBI chrNW_004624761:18,485,286...18,488,988
Ensembl chrNW_004624761:18,485,440...18,488,882 		JBrowse link
G Zc3h14 zinc finger CCCH-type containing 14 involved_in ISO (PMID:27563065) UniProt PMID:27563065 NCBI chrNW_004624734:13,734,406...13,787,341
Ensembl chrNW_004624734:13,734,401...13,788,057 		JBrowse link
3'-UTR-mediated mRNA stabilization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Angel2 angel homolog 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624771:18,334,720...18,353,080
Ensembl chrNW_004624771:18,336,190...18,353,087 		JBrowse link
G Boll boule homolog, RNA binding protein involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624889:2,580,541...2,619,512
Ensembl chrNW_004624889:2,580,623...2,614,192 		JBrowse link
G Dazl deleted in azoospermia like involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624821:1,836,632...1,854,048 JBrowse link
G Elavl1 ELAV like RNA binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624828:913,001...948,826
Ensembl chrNW_004624828:914,141...948,831 		JBrowse link
G Elavl4 ELAV like RNA binding protein 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624859:2,875,652...3,023,142
Ensembl chrNW_004624859:2,874,945...3,023,001 		JBrowse link
G Hnrnpa0 heterogeneous nuclear ribonucleoprotein A0 involved_in ISO (PMID:12456657) UniProt PMID:12456657 NCBI chrNW_004624733:9,265,784...9,271,559
Ensembl chrNW_004624733:9,266,607...9,267,527 		JBrowse link
G Hnrnpc heterogeneous nuclear ribonucleoprotein C involved_in ISO (PMID:16010978) UniProt PMID:16010978 NCBI chrNW_004624825:7,198,387...7,276,936
Ensembl chrNW_004624825:7,205,292...7,276,889 		JBrowse link
G Mapkapk2 MAPK activated protein kinase 2 involved_in ISO (PMID:14517288), (PMID:15014438), (PMID:20932473) UniProt PMID:14517288 PMID:15014438 PMID:20932473 NCBI chrNW_004624807:4,726,511...4,774,945
Ensembl chrNW_004624807:4,724,234...4,796,143 		JBrowse link
G Myd88 MYD88 innate immune signal transduction adaptor involved_in ISO (PMID:15294994) BHF-UCL PMID:15294994 NCBI chrNW_004624731:2,677,259...2,681,408
Ensembl chrNW_004624731:2,677,290...2,681,489 		JBrowse link
G Nicol1 NELL2 interacting cell ontogeny regulator 1 involved_in ISO (PMID:38625739) UniProt PMID:38625739 NCBI chrNW_004624755:25,477,354...25,478,742
Ensembl chrNW_004624755:25,477,323...25,478,735 		JBrowse link
G Ptbp1 polypyrimidine tract binding protein 1 ISO RGD PMID:11696543 RGD:10045987 NCBI chrNW_004624828:7,750,419...7,762,645
Ensembl chrNW_004624828:7,750,323...7,762,589 		JBrowse link
G Rbm10 RNA binding motif protein 10 acts_upstream_of_or_within ISO (PMID:19508861) MGI PMID:19508861 NCBI chrNW_004624887:3,921,934...3,953,739
Ensembl chrNW_004624887:3,923,986...3,957,133 		JBrowse link
G Rbm38 RNA binding motif protein 38 involved_in ISO (PMID:17050675) UniProt PMID:17050675 NCBI chrNW_004624741:23,854,069...23,868,016
Ensembl chrNW_004624741:23,854,023...23,868,345 		JBrowse link
G Rbm47 RNA binding motif protein 47 involved_in ISO (PMID:34160127)
(PMID:29844590)		 UniProt PMID:29844590 PMID:34160127 NCBI chrNW_004624761:26,429,130...26,588,563
Ensembl chrNW_004624761:26,513,759...26,588,950 		JBrowse link
G Tardbp TAR DNA binding protein involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624818:1,759,496...1,789,806
Ensembl chrNW_004624818:1,759,497...1,789,813 		JBrowse link
G Tirap TIR domain containing adaptor protein involved_in ISO (PMID:15294994) BHF-UCL PMID:15294994 NCBI chrNW_004624812:433,540...445,517
Ensembl chrNW_004624812:439,319...446,646 		JBrowse link
G Zfp36 ZFP36 ring finger protein involved_in ISO (PMID:15014438) UniProt PMID:15014438 NCBI chrNW_004624794:12,732,222...12,738,006
Ensembl chrNW_004624794:12,734,191...12,737,971 		JBrowse link
CRD-mediated mRNA stabilization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csde1 cold shock domain containing E1 involved_in ISO (PMID:11051545) ComplexPortal PMID:11051545 NCBI chrNW_004624772:10,369,447...10,406,718 JBrowse link
G Dhx9 DExH-box helicase 9 involved_in ISO (PMID:19029303) UniProt PMID:19029303 NCBI chrNW_004624814:10,863,079...10,923,842
Ensembl chrNW_004624814:10,863,337...10,921,075 		JBrowse link
G Hnrnpd heterogeneous nuclear ribonucleoprotein D involved_in ISO (PMID:11051545) ComplexPortal PMID:11051545 NCBI chrNW_004624757:8,532,373...8,549,840
Ensembl chrNW_004624757:8,531,601...8,549,835 		JBrowse link
G Hnrnpu heterogeneous nuclear ribonucleoprotein U involved_in ISO (PMID:19029303) UniProt PMID:19029303 NCBI chrNW_004624771:14,756,088...14,766,106
Ensembl chrNW_004624771:14,756,100...14,765,832 		JBrowse link
G Igf2bp1 insulin like growth factor 2 mRNA binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624795:5,352,932...5,391,617
Ensembl chrNW_004624795:5,353,005...5,385,521 		JBrowse link
G Igf2bp2 insulin like growth factor 2 mRNA binding protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624730:70,914,763...71,061,313
Ensembl chrNW_004624730:70,914,804...71,059,642 		JBrowse link
G Igf2bp3 insulin like growth factor 2 mRNA binding protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624739:7,154,893...7,319,724
Ensembl chrNW_004624739:7,158,020...7,319,720 		JBrowse link
G Pabpc1 poly(A) binding protein cytoplasmic 1 involved_in ISO (PMID:11051545) ComplexPortal PMID:11051545 NCBI chrNW_004624763:7,552,541...7,568,047
Ensembl chrNW_004624763:7,550,307...7,567,918 		JBrowse link
G Paip1 poly(A) binding protein interacting protein 1 involved_in ISO (PMID:11051545) ComplexPortal PMID:11051545 NCBI chrNW_004624759:11,646,632...11,687,981
Ensembl chrNW_004624759:11,646,848...11,686,871 		JBrowse link
G Syncrip synaptotagmin binding cytoplasmic RNA interacting protein involved_in ISO (PMID:11051545), (PMID:19029303)
(PMID:19029303)		 ComplexPortal
UniProt		 PMID:11051545 PMID:19029303 NCBI chrNW_004624799:8,616,787...8,657,466
Ensembl chrNW_004624799:8,616,808...8,652,923 		JBrowse link
G Ybx1 Y-box binding protein 1 involved_in ISO (PMID:19029303) UniProt PMID:19029303 NCBI chrNW_004624892:1,939,641...1,957,621
Ensembl chrNW_004624892:1,939,098...1,957,623 		JBrowse link
negative regulation of 3'-UTR-mediated mRNA stabilization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mettl16 methyltransferase 16, RNA N6-adenosine involved_in ISO (PMID:28525753) UniProt PMID:28525753 NCBI chrNW_004624786:5,063,127...5,134,387
Ensembl chrNW_004624786:5,070,311...5,134,669 		JBrowse link
G Qki QKI, KH domain containing RNA binding involved_in ISO (PMID:31868295) UniProt PMID:31868295 NCBI chrNW_004624785:15,738,231...15,845,051
Ensembl chrNW_004624785:15,739,187...15,845,024 		JBrowse link
G Zfp36 ZFP36 ring finger protein involved_in ISO (PMID:21606497) UniProt PMID:21606497 NCBI chrNW_004624794:12,732,222...12,738,006
Ensembl chrNW_004624794:12,734,191...12,737,971 		JBrowse link
positive regulation of 3'-UTR-mediated mRNA stabilization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arid5a AT-rich interaction domain 5A involved_in ISO (PMID:32209697) UniProt PMID:32209697 NCBI chrNW_004624749:2,491,162...2,504,580
Ensembl chrNW_004624749:2,491,156...2,506,110 		JBrowse link
G Elavl4 ELAV like RNA binding protein 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624859:2,875,652...3,023,142
Ensembl chrNW_004624859:2,874,945...3,023,001 		JBrowse link
G Larp4b La ribonucleoprotein 4B involved_in ISO (PMID:26001795) FlyBase PMID:26001795 NCBI chrNW_004624775:10,055,200...10,149,178
Ensembl chrNW_004624775:10,083,476...10,145,712 		JBrowse link
G Qki QKI, KH domain containing RNA binding involved_in ISO (PMID:28188285) UniProt PMID:28188285 NCBI chrNW_004624785:15,738,231...15,845,051
Ensembl chrNW_004624785:15,739,187...15,845,024 		JBrowse link
G Rbm24 RNA binding motif protein 24 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624756:9,253,310...9,262,859
Ensembl chrNW_004624756:9,250,945...9,262,899 		JBrowse link
G Tent4a terminal nucleotidyltransferase 4A involved_in ISO (PMID:30026317) UniProt PMID:30026317 NCBI chrNW_004624751:4,387,075...4,418,516
Ensembl chrNW_004624751:4,386,857...4,416,719 		JBrowse link
G Tent4b terminal nucleotidyltransferase 4B involved_in ISO (PMID:30026317) UniProt PMID:30026317 NCBI chrNW_004624757:6,415,226...6,491,539
Ensembl chrNW_004624757:6,422,421...6,491,434 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17637
    biological regulation 11843
      regulation of biological quality 3004
        regulation of RNA stability 181
          regulation of mRNA stability 168
            mRNA stabilization 68
              3'-UTR-mediated mRNA stabilization + 24
              CRD-mediated mRNA stabilization 11
Path 2
Term Annotations click to browse term
  biological_process 17637
    biological regulation 11843
      regulation of biological process 11485
        regulation of cellular process 11159
          regulation of metabolic process 5978
            regulation of biosynthetic process 4844
              regulation of macromolecule biosynthetic process 4652
                regulation of gene expression 4541
                  negative regulation of gene expression 1079
                    mRNA catabolic process 249
                      regulation of mRNA catabolic process 183
                        regulation of mRNA stability 168
                          mRNA stabilization 68
                            3'-UTR-mediated mRNA stabilization + 24
                            CRD-mediated mRNA stabilization 11
paths to the root