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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of mRNA stability
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Accession:GO:0043488 term browser browse the term
Definition:Any process that modulates the propensity of mRNA molecules to degradation. Includes processes that both stabilize and destabilize mRNAs.


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regulation of mRNA stability term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alkbh5 alkB homolog 5, RNA demethylase JBrowse link 10 46,906,314 46,927,759 RGD:1600115
RGD:1624291
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 JBrowse link 15 27,849,943 27,852,083 RGD:1624291
RGD:1600115
G Brf1 BRF1, RNA polymerase III transcription initiation factor subunit JBrowse link 6 137,762,230 137,808,573 RGD:1624291
G Cacng7 calcium voltage-gated channel auxiliary subunit gamma 7 JBrowse link 1 64,374,547 64,405,380 RGD:13524564
G Calcr calcitonin receptor JBrowse link 4 28,627,439 28,702,559 RGD:1624291
RGD:1600115
G Carhsp1 calcium regulated heat stable protein 1 JBrowse link 10 7,041,510 7,055,107 RGD:1624291
RGD:13792537
RGD:1600115
G Csdc2 cold shock domain containing C2 JBrowse link 7 123,168,811 123,183,336 RGD:13792537
G Dcp2 decapping mRNA 2 JBrowse link 18 35,489,274 35,671,676 RGD:1624291
G Dhx36 DEAH-box helicase 36 JBrowse link 2 152,785,844 152,824,549 RGD:1600115
RGD:1624291
G Elavl4 ELAV like RNA binding protein 4 JBrowse link 5 130,001,387 130,144,557 RGD:9586719
G Fmr1 FMRP translational regulator 1 JBrowse link X 154,684,924 154,722,369 RGD:1624291
RGD:13792537
RGD:1600115
G Fxr1 FMR1 autosomal homolog 1 JBrowse link 2 120,529,716 120,570,356 RGD:13792537
G Fxr2 FMR1 autosomal homolog 2 JBrowse link 10 56,237,814 56,257,877 RGD:13792537
G Hnrnpd heterogeneous nuclear ribonucleoprotein D JBrowse link 14 11,256,163 11,274,684 RGD:1624291
G Khsrp KH-type splicing regulatory protein JBrowse link 9 10,013,795 10,023,670 RGD:1624291
RGD:1600115
G Pabpc4 poly(A) binding protein, cytoplasmic 4 JBrowse link 5 140,978,893 140,994,732 RGD:1624291
G Pcbp4 poly(rC) binding protein 4 JBrowse link 8 115,154,848 115,165,706 RGD:1624291
G Pcid2 PCI domain containing 2 JBrowse link 16 81,757,582 81,783,047 RGD:1624291
G Pum1 pumilio RNA-binding family member 1 JBrowse link 5 148,781,239 148,911,776 RGD:1624291
RGD:13792537
G Pum2 pumilio RNA-binding family member 2 JBrowse link 6 33,786,184 33,865,693 RGD:1624291
RGD:13792537
G Rbm24 RNA binding motif protein 24 JBrowse link 17 18,671,037 18,682,876 RGD:1624291
G Rc3h1 ring finger and CCCH-type domains 1 JBrowse link 13 78,723,028 78,794,663 RGD:1624291
G Rnasel ribonuclease L JBrowse link 13 71,188,712 71,202,636 RGD:1624291
G Samd4a sterile alpha motif domain containing 4A JBrowse link 15 23,666,543 23,879,067 RGD:1600115
RGD:13792537
G Samd4b sterile alpha motif domain containing 4B JBrowse link 1 85,324,017 85,362,266 RGD:13792537
G Scgb1a1 secretoglobin family 1A member 1 JBrowse link 1 225,279,698 225,283,246 RGD:1624291
G Vim vimentin JBrowse link 17 80,882,715 80,891,200 RGD:1600115
RGD:1624291
G Ythdf2 YTH N(6)-methyladenosine RNA binding protein 2 JBrowse link 5 150,364,490 150,390,173 RGD:1624291
G Zc3h14 zinc finger CCCH type containing 14 JBrowse link 6 122,729,834 122,767,462 RGD:13792537
RGD:1600115
G Zfp36 zinc finger protein 36 JBrowse link 1 85,380,088 85,382,565 RGD:1600115
RGD:1624291
G Zfp36l1 zinc finger protein 36, C3H type-like 1 JBrowse link 6 103,308,032 103,313,074 RGD:11344953
RGD:1624291
RGD:1600115
RGD:11344945
G Zfp36l2 zinc finger protein 36, C3H type-like 2 JBrowse link 6 7,417,416 7,423,447 RGD:1624291
3'-UTR-mediated mRNA destabilization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cpeb3 cytoplasmic polyadenylation element binding protein 3 JBrowse link 1 255,660,165 255,842,671 RGD:1624291
G Dhx36 DEAH-box helicase 36 JBrowse link 2 152,785,844 152,824,549 RGD:1600115
RGD:1624291
G Dnd1 DND microRNA-mediated repression inhibitor 1 JBrowse link 18 29,608,588 29,611,212 RGD:1624291
G Hnrnpd heterogeneous nuclear ribonucleoprotein D JBrowse link 14 11,256,163 11,274,684 RGD:10042974
G Khsrp KH-type splicing regulatory protein JBrowse link 9 10,013,795 10,023,670 RGD:1600115
RGD:1624291
G Mov10 Mov10 RISC complex RNA helicase JBrowse link 2 207,277,088 207,301,245 RGD:1624291
G Plekhn1 pleckstrin homology domain containing N1 JBrowse link 5 173,646,055 173,654,140 RGD:1624291
RGD:13792537
G Qk quaking JBrowse link 1 50,983,647 51,050,692 RGD:1624291
G Rbm24 RNA binding motif protein 24 JBrowse link 17 18,671,037 18,682,876 RGD:1624291
G Rc3h1 ring finger and CCCH-type domains 1 JBrowse link 13 78,723,028 78,794,663 RGD:1624291
G Tardbp TAR DNA binding protein JBrowse link 5 165,432,089 165,442,232 RGD:1624291
G Trim71 tripartite motif containing 71 JBrowse link 8 122,553,015 122,604,787 RGD:1624291
G Upf1 UPF1, RNA helicase and ATPase JBrowse link 16 20,824,888 20,845,632 RGD:1624291
G Zc3h12a zinc finger CCCH type containing 12A JBrowse link 5 143,111,342 143,120,131 RGD:1624291
RGD:13792537
RGD:1600115
G Zc3h12d zinc finger CCCH type containing 12D JBrowse link 1 1,937,620 1,972,919 RGD:1624291
G Zfp36 zinc finger protein 36 JBrowse link 1 85,380,088 85,382,565 RGD:1600115
RGD:1624291
G Zfp36l1 zinc finger protein 36, C3H type-like 1 JBrowse link 6 103,308,032 103,313,074 RGD:1600115
RGD:1624291
G Zfp36l2 zinc finger protein 36, C3H type-like 2 JBrowse link 6 7,417,416 7,423,447 RGD:1624291
3'-UTR-mediated mRNA stabilization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Angel2 angel homolog 2 JBrowse link 13 109,505,021 109,520,976 RGD:1624291
RGD:13792537
G Boll boule homolog, RNA binding protein JBrowse link 9 61,836,517 61,975,640 RGD:13792537
G Dazl deleted in azoospermia-like JBrowse link 9 12,633,983 12,651,017 RGD:13792537
G Elavl1 ELAV like RNA binding protein 1 JBrowse link 12 2,461,502 2,502,432 RGD:1600115
RGD:1624291
G Elavl4 ELAV like RNA binding protein 4 JBrowse link 5 130,001,387 130,144,557 RGD:1624291
RGD:1600115
G Hnrnpa0 heterogeneous nuclear ribonucleoprotein A0 RGD:1624291
G Hnrnpc heterogeneous nuclear ribonucleoprotein C JBrowse link 15 28,486,605 28,517,353 RGD:1624291
G LOC108348134 protein boule-like JBrowse link 9 64,447,890 64,573,812 RGD:13792537
G LOC681410 hypothetical protein LOC681410 JBrowse link 17 6,909,166 6,912,145 RGD:1600115
G Mapkapk2 MAPK activated protein kinase 2 JBrowse link 13 47,785,157 47,871,684 RGD:1624291
G Myd88 MYD88, innate immune signal transduction adaptor JBrowse link 8 128,022,512 128,027,462 RGD:1624291
G Ptbp1 polypyrimidine tract binding protein 1 JBrowse link 7 12,663,965 12,673,723 RGD:10045987
G Rbm10 RNA binding motif protein 10 JBrowse link X 1,754,869 1,786,973 RGD:1624291
RGD:1600115
G Rbm38 RNA binding motif protein 38 JBrowse link 3 171,037,891 171,050,500 RGD:1624291
G Tardbp TAR DNA binding protein JBrowse link 5 165,432,089 165,442,232 RGD:1624291
G Tirap TIR domain containing adaptor protein JBrowse link 8 36,382,029 36,399,625 RGD:1624291
G Zfp36 zinc finger protein 36 JBrowse link 1 85,380,088 85,382,565 RGD:1624291
RGD:1600115
CRD-mediated mRNA stabilization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dhx9 DExH-box helicase 9 JBrowse link 13 70,885,503 70,922,278 RGD:1624291
G Hnrnpu heterogeneous nuclear ribonucleoprotein U JBrowse link 13 96,222,093 96,238,845 RGD:1600115
RGD:13792537
RGD:1624291
G Igf2bp1 insulin-like growth factor 2 mRNA binding protein 1 JBrowse link 10 83,774,178 83,823,323 RGD:1624291
G Syncrip synaptotagmin binding, cytoplasmic RNA interacting protein JBrowse link 8 96,100,692 96,266,342 RGD:1600115
RGD:13792537
RGD:1624291
G Ybx1 Y box binding protein 1 JBrowse link 5 138,319,754 138,336,721 RGD:1624291
RGD:1600115
mRNA destabilization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cnot6l CCR4-NOT transcription complex, subunit 6-like JBrowse link 14 15,059,101 15,148,255 RGD:1624291
G Fto FTO, alpha-ketoglutarate dependent dioxygenase JBrowse link 19 16,774,549 17,115,098 RGD:1600115
RGD:1624291
G Gigyf2 GRB10 interacting GYF protein 2 JBrowse link 9 94,425,191 94,550,431 RGD:1624291
G Hnrnpr heterogeneous nuclear ribonucleoprotein R JBrowse link 5 154,668,194 154,699,967 RGD:9854643
G Mettl14 methyltransferase like 14 JBrowse link 2 227,566,811 227,583,047 RGD:1624291
G Mettl16 methyltransferase like 16 JBrowse link 10 61,626,595 61,682,947 RGD:1624291
RGD:1600115
G Mettl3 methyltransferase-like 3 JBrowse link 15 28,710,299 28,721,491 RGD:1624291
G Pum1 pumilio RNA-binding family member 1 JBrowse link 5 148,781,239 148,911,776 RGD:1624291
G Rbm24 RNA binding motif protein 24 JBrowse link 17 18,671,037 18,682,876 RGD:1624291
G Rida reactive intermediate imine deaminase A homolog JBrowse link 7 73,256,506 73,270,308 RGD:1600115
RGD:1624291
G Rock1 Rho-associated coiled-coil containing protein kinase 1 JBrowse link 18 1,273,490 1,390,790 RGD:1600115
RGD:1624291
G Rock2 Rho-associated coiled-coil containing protein kinase 2 JBrowse link 6 42,180,864 42,289,910 RGD:1624291
G Ythdf1 YTH N(6)-methyladenosine RNA binding protein 1 JBrowse link 3 176,415,911 176,431,423 RGD:13792537
G Ythdf2 YTH N(6)-methyladenosine RNA binding protein 2 JBrowse link 5 150,364,490 150,390,173 RGD:1624291
RGD:13792537
G Ythdf3 YTH N(6)-methyladenosine RNA binding protein 3 JBrowse link 2 100,677,388 100,711,365 RGD:1624291
RGD:13792537
mRNA stabilization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apobec1 apolipoprotein B mRNA editing enzyme catalytic subunit 1 JBrowse link 4 155,386,367 155,414,034 RGD:1624291
G Axin2 axin 2 JBrowse link 10 97,212,483 97,238,824 RGD:1624291
RGD:1600115
G Cirbp cold inducible RNA binding protein JBrowse link 7 12,400,066 12,405,054 RGD:1624291
RGD:1600115
G Dicer1 dicer 1 ribonuclease III JBrowse link 6 128,388,084 128,453,234 RGD:1624291
G Dnd1 DND microRNA-mediated repression inhibitor 1 JBrowse link 18 29,608,588 29,611,212 RGD:13792537
G E2f1 E2F transcription factor 1 JBrowse link 3 150,062,895 150,073,721 RGD:1624291
G Elavl1 ELAV like RNA binding protein 1 JBrowse link 12 2,461,502 2,502,432 RGD:1624291
RGD:1600115
G Fus FUS RNA binding protein JBrowse link 1 199,412,805 199,426,705 RGD:1624291
G Gdnf glial cell derived neurotrophic factor JBrowse link 2 56,884,181 56,912,964 RGD:1624291
RGD:1600115
G Hnrnpd heterogeneous nuclear ribonucleoprotein D JBrowse link 14 11,256,163 11,274,684 RGD:1357938
G Hnrnpu heterogeneous nuclear ribonucleoprotein U JBrowse link 13 96,222,093 96,238,845 RGD:1624291
G Larp1 La ribonucleoprotein 1, translational regulator JBrowse link 10 43,435,738 43,501,186 RGD:1624291
G Mapkapk2 MAPK activated protein kinase 2 JBrowse link 13 47,785,157 47,871,684 RGD:1624291
G Meioc meiosis specific with coiled-coil domain JBrowse link 10 90,622,954 90,641,883 RGD:1624291
RGD:13792537
G Mtor mechanistic target of rapamycin kinase JBrowse link 5 165,263,813 165,373,967 RGD:10040969
G Noct nocturnin JBrowse link 2 140,286,661 140,306,869 RGD:1624291
RGD:1600115
G Qk quaking JBrowse link 1 50,983,647 51,050,692 RGD:10045995
G Rbm24 RNA binding motif protein 24 JBrowse link 17 18,671,037 18,682,876 RGD:1624291
G Rbm46 RNA binding motif protein 46 JBrowse link 2 181,828,931 181,874,223 RGD:1624291
G Slc11a1 solute carrier family 11 member 1 JBrowse link 9 81,655,590 81,666,697 RGD:1624291
RGD:1600115
G Taf15 TATA-box binding protein associated factor 15 JBrowse link 10 70,689,863 70,721,892 RGD:1624291
G Tent5a terminal nucleotidyltransferase 5A JBrowse link 8 92,935,474 92,942,267 RGD:13792537
G Tent5b terminal nucleotidyltransferase 5B JBrowse link 5 151,692,068 151,699,381 RGD:13792537
G Tent5c terminal nucleotidyltransferase 5C JBrowse link 2 202,797,766 202,816,562 RGD:1600115
RGD:13792537
RGD:1624291
G Tent5d terminal nucleotidyltransferase 5D JBrowse link X 78,911,641 78,994,467 RGD:13792537
G Thrap3 thyroid hormone receptor associated protein 3 JBrowse link 5 144,178,248 144,221,318 RGD:1624291
RGD:1600115
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:1580563
G Vip vasoactive intestinal peptide JBrowse link 1 42,169,307 42,177,582 RGD:1600115
G Ybx1 Y box binding protein 1 JBrowse link 5 138,319,754 138,336,721 RGD:1624291
RGD:1600115
G Ybx2 Y box binding protein 2 JBrowse link 10 56,546,689 56,552,339 RGD:1624291
negative regulation of 3'-UTR-mediated mRNA stabilization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mettl16 methyltransferase like 16 JBrowse link 10 61,626,595 61,682,947 RGD:1624291
RGD:1600115
positive regulation of 3'-UTR-mediated mRNA stabilization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Elavl4 ELAV like RNA binding protein 4 JBrowse link 5 130,001,387 130,144,557 RGD:1624291
RGD:1600115
G Rbm24 RNA binding motif protein 24 JBrowse link 17 18,671,037 18,682,876 RGD:1624291
G Tent4a terminal nucleotidyltransferase 4A JBrowse link 1 36,400,056 36,433,238 RGD:1624291
G Tent4b terminal nucleotidyltransferase 4B JBrowse link 19 19,771,289 19,834,759 RGD:1624291
regulation of mitochondrial mRNA stability term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fastk Fas-activated serine/threonine kinase JBrowse link 4 7,260,521 7,264,590 RGD:1600115
G Fastkd1 FAST kinase domains 1 JBrowse link 3 55,925,598 55,951,584 RGD:1624291
G Fastkd2 FAST kinase domains 2 JBrowse link 9 70,448,386 70,471,420 RGD:1600115
G Fastkd3 FAST kinase domains 3 JBrowse link 1 37,734,400 37,742,932 RGD:1624291
RGD:1600115
G Pde12 phosphodiesterase 12 JBrowse link 16 2,357,028 2,367,069 RGD:1600115
RGD:1624291
G Tbrg4 transforming growth factor beta regulator 4 JBrowse link 14 86,876,800 86,885,603 RGD:1624291
RGD:1600115
regulation of mRNA stability involved in cellular response to UV term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Npm1 nucleophosmin 1 JBrowse link 10 18,080,949 18,091,062 RGD:1624291
regulation of mRNA stability involved in response to oxidative stress term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hnrnpm heterogeneous nuclear ribonucleoprotein M JBrowse link 7 18,516,253 18,554,536 RGD:13792537
G Myef2 myelin expression factor 2 JBrowse link 3 117,353,490 117,389,582 RGD:13792537
regulation of mRNA stability involved in response to stress term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Igf2bp1 insulin-like growth factor 2 mRNA binding protein 1 JBrowse link 10 83,774,178 83,823,323 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    biological regulation 13636
      regulation of biological quality 4252
        regulation of RNA stability 117
          regulation of mRNA stability 106
            mRNA destabilization + 32
            mRNA stabilization + 51
            regulation of 3'-UTR-mediated mRNA stabilization + 5
            regulation of mRNA stability involved in cellular response to UV 1
            regulation of mRNA stability involved in response to stress + 3
            regulation of mRNA stability, ncRNA-mediated 0
            regulation of mitochondrial mRNA stability 6
Path 2
Term Annotations click to browse term
  biological_process 19858
    metabolic process 12097
      cellular metabolic process 10918
        cellular aromatic compound metabolic process 5567
          nucleobase-containing compound metabolic process 5344
            nucleic acid metabolic process 4850
              RNA metabolic process 4347
                RNA catabolic process 261
                  mRNA catabolic process 225
                    regulation of mRNA catabolic process 129
                      regulation of mRNA stability 106
                        mRNA destabilization + 32
                        mRNA stabilization + 51
                        regulation of 3'-UTR-mediated mRNA stabilization + 5
                        regulation of mRNA stability involved in cellular response to UV 1
                        regulation of mRNA stability involved in response to stress + 3
                        regulation of mRNA stability, ncRNA-mediated 0
                        regulation of mitochondrial mRNA stability 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.