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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of alpha-beta T cell proliferation
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Accession:GO:0046642 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of alpha-beta T cell proliferation.
Synonyms:exact_synonym: down regulation of alpha-beta T cell proliferation;   downregulation of alpha-beta T cell proliferation;   negative regulation of alpha-beta T lymphocyte proliferation
 narrow_synonym: inhibition of alpha-beta T cell proliferation



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negative regulation of alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btla B and T lymphocyte associated acts_upstream_of_or_within ISO MGI:3027713 (PMID:15568026) RGD PMID:15568026 NCBI chr11:55,563,683...55,588,187
Ensembl chr11:55,564,899...55,587,181
JBrowse link
G Clec4g C-type lectin domain family 4, member G acts_upstream_of_or_within ISO MGI:5510586 (PMID:23487419) RGD PMID:23487419 NCBI chr12:1,780,370...1,785,027
Ensembl chr12:1,780,371...1,784,985
JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of_or_within ISO MGI:1857034 (PMID:16945588) RGD PMID:16945588 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838
JBrowse link
G Tnfrsf14 TNF receptor superfamily member 14 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:165,486,069...165,494,421
Ensembl chr 5:165,484,262...165,493,703
JBrowse link
negative regulation of CD4-positive, alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg2 arginase 2 involved_in IEA
ISO
GO_REF:0000107
(MGI:5908533|PMID:25009204)
Ensembl
RGD
PMID:25009204 GO_REF:0000107 MGI:5908533 NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378
JBrowse link
G Cblb Cbl proto-oncogene B involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2180572 (PMID:14973438)
Ensembl
RGD
PMID:14973438 GO_REF:0000107 NCBI chr11:48,589,878...48,756,940
Ensembl chr11:48,592,703...48,756,839
JBrowse link
G Cd274 CD274 molecule involved_in ISO (PMID:24691993) RGD PMID:24691993 NCBI chr 1:227,116,674...227,137,379
Ensembl chr 1:227,116,649...227,134,450
JBrowse link
G Cd44 CD44 molecule involved_in ISO (MGI:5688819|PMID:25065622) RGD PMID:25065622 MGI:5688819 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of_or_within ISO (PMID:17028180) RGD PMID:17028180 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838
JBrowse link
G Itch itchy E3 ubiquitin protein ligase acts_upstream_of_or_within ISO MGI:1856404 (PMID:14973438) RGD PMID:14973438 NCBI chr 3:143,642,348...143,733,745
Ensembl chr 3:143,645,637...143,733,543
JBrowse link
G Lgals5 galectin 5 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:63,853,949...63,857,198
Ensembl chr10:63,853,935...63,857,153
JBrowse link
G Lgals9 galectin 9 involved_in ISO
IBA
(PMID:20209097)
(MGI:5688819|PMID:25065622)
GO_REF:0000033
RGD
GO_Central
PMID:20209097 PMID:25065622 GO_REF:0000033 MGI:5688819 NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045
JBrowse link
G Ndfip1 Nedd4 family interacting protein 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3695433 (PMID:17137798)
Ensembl
RGD
PMID:17137798 GO_REF:0000107 NCBI chr18:30,265,808...30,316,068
Ensembl chr18:30,250,613...30,322,311
JBrowse link
G Tarm1 T cell-interacting, activating receptor on myeloid cells 1 involved_in ISO (MGI:5908526|PMID:26311901) RGD PMID:26311901 MGI:5908526 NCBI chr 1:65,666,742...65,682,402
Ensembl chr 1:65,671,902...65,679,626
JBrowse link
G Tnfrsf14 TNF receptor superfamily member 14 acts_upstream_of_or_within ISO (PMID:15568026) RGD PMID:15568026 NCBI chr 5:165,486,069...165,494,421
Ensembl chr 5:165,484,262...165,493,703
JBrowse link
G Twsg1 twisted gastrulation BMP signaling modulator 1 involved_in ISO (PMID:17164348) RGD PMID:17164348 NCBI chr 9:105,533,116...105,567,460
Ensembl chr 9:105,533,136...105,567,479
JBrowse link
G Vsir V-set immunoregulatory receptor involved_in
acts_upstream_of_or_within
ISO (PMID:24691993)
(PMID:21383057)
RGD PMID:21383057 PMID:24691993 NCBI chr20:28,281,582...28,307,262
Ensembl chr20:28,281,596...28,303,878
JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in ISO (PMID:10887101) RGD PMID:10887101 NCBI chr13:77,248,687...77,252,343
Ensembl chr13:77,248,717...77,252,329
JBrowse link
negative regulation of CD8-positive, alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc4a2 solute carrier family 4 member 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:6840447|PMID:24515893)
UniProt
RGD
PMID:24515893 GO_REF:0000024 MGI:6840447 NCBI chr 4:10,736,419...10,754,407
Ensembl chr 4:10,736,425...10,752,965
JBrowse link
G Vsir V-set immunoregulatory receptor involved_in ISO (PMID:24691993) RGD PMID:24691993 NCBI chr20:28,281,582...28,307,262
Ensembl chr20:28,281,596...28,303,878
JBrowse link
negative regulation of NK T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zbtb7b zinc finger and BTB domain containing 7B involved_in ISO (MGI:5449456|PMID:23105140) RGD PMID:23105140 MGI:5449456 NCBI chr 2:174,795,831...174,811,980
Ensembl chr 2:174,797,453...174,814,236
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19692
    immune system process 2822
      leukocyte activation 1032
        lymphocyte activation 837
          T cell activation 591
            T cell proliferation 249
              negative regulation of T cell proliferation 84
                negative regulation of alpha-beta T cell proliferation 18
                  negative regulation of CD4-positive, alpha-beta T cell proliferation 14
                  negative regulation of CD8-positive, alpha-beta T cell proliferation 2
                  negative regulation of NK T cell proliferation 1
Path 2
Term Annotations click to browse term
  biological_process 19692
    biological regulation 13305
      regulation of biological process 12902
        regulation of cellular process 12354
          regulation of cell activation 650
            regulation of leukocyte activation 594
              regulation of lymphocyte activation 514
                regulation of T cell activation 378
                  regulation of alpha-beta T cell activation 126
                    regulation of alpha-beta T cell proliferation 50
                      negative regulation of alpha-beta T cell proliferation 18
                        negative regulation of CD4-positive, alpha-beta T cell proliferation 14
                        negative regulation of CD8-positive, alpha-beta T cell proliferation 2
                        negative regulation of NK T cell proliferation 1
paths to the root