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ONTOLOGY REPORT - ANNOTATIONS

Term:protein serine/threonine kinase activator activity
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Accession:GO:0043539 term browser browse the term
Definition:Binds to and increases the activity of a protein serine/threonine kinase.
Synonyms:exact_synonym: protein ser/thr kinase activator activity


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protein serine/threonine kinase activator activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACSL1 acyl-CoA synthetase long chain family member 1 enables IEA Ensembl GO_REF:0000107 NCBI chr16:45,735,675...45,806,235
Ensembl chr16:45,735,703...45,804,970 		JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing enables ISO (PMID:20667975) MGI PMID:20667975 NCBI chr34:19,398,310...19,410,519
Ensembl chr34:19,354,825...19,409,844 		JBrowse link
G ALS2 alsin Rho guanine nucleotide exchange factor ALS2 enables IEA Ensembl GO_REF:0000107 NCBI chr37:10,755,595...10,825,073
Ensembl chr37:10,756,515...10,812,292 		JBrowse link
G ATG13 autophagy related 13 enables IEA Ensembl GO_REF:0000107 NCBI chr18:42,834,538...42,886,873
Ensembl chr18:42,836,755...42,886,855 		JBrowse link
G B9D2 B9 domain containing 2 enables ISO (PMID:32644293)
(PMID:25065622)		 UniProt PMID:25065622 PMID:32644293 NCBI chr 1:112,621,832...112,627,726
Ensembl chr 1:112,621,633...112,643,885 		JBrowse link
G BMP2 bone morphogenetic protein 2 enables IEA Ensembl GO_REF:0000107 NCBI chr24:15,199,667...15,211,509
Ensembl chr24:15,200,291...15,212,217 		JBrowse link
G BMP4 bone morphogenetic protein 4 enables ISO (PMID:14749725) UniProt PMID:14749725 NCBI chr 8:29,997,563...30,254,307
Ensembl chr 8:29,997,569...30,004,557 		JBrowse link
G BMP7 bone morphogenetic protein 7 enables ISO (PMID:31208997) UniProt PMID:31208997 NCBI chr24:42,203,183...42,294,105
Ensembl chr24:42,204,823...42,294,653 		JBrowse link
G CAB39 calcium binding protein 39 enables IEA Ensembl GO_REF:0000107 NCBI chr25:42,752,798...42,801,257
Ensembl chr25:42,703,332...42,799,279 		JBrowse link
G CALM1 calmodulin 1 enables ISO (PMID:14722083), (PMID:35568036) UniProt PMID:14722083 PMID:35568036 NCBI chr 8:61,398,231...61,408,874
Ensembl chr 8:61,398,244...61,406,195 		JBrowse link
G CALM2 calmodulin 2 enables IEA Ensembl GO_REF:0000107 NCBI chr10:49,299,698...49,314,533
Ensembl chr10:49,299,897...49,314,457 		JBrowse link
G CALM3 calmodulin 3 enables ISO (PMID:14722083), (PMID:35568036) UniProt PMID:14722083 PMID:35568036 NCBI chr 1:109,284,729...109,294,491
Ensembl chr 1:109,286,155...109,294,391 		JBrowse link
G CCDC88A coiled-coil domain containing 88A enables ISO (PMID:15753085) UniProt PMID:15753085 NCBI chr10:56,167,907...56,300,974
Ensembl chr10:56,170,479...56,300,908 		JBrowse link
G CD40LG CD40 ligand enables IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:107,001,421...107,023,007
Ensembl chr  X:107,010,890...107,023,006 		JBrowse link
G CDK5R1 cyclin dependent kinase 5 regulatory subunit 1 enables ISO
IEA		 RGD
Ensembl		 PMID:8662984 GO_REF:0000107 RGD:632374 NCBI chr 9:40,481,111...40,502,689
Ensembl chr 9:40,501,646...40,502,569 		JBrowse link
G DAB2IP DAB2 interacting protein enables IEA Ensembl GO_REF:0000107 NCBI chr 9:60,725,887...60,918,242
Ensembl chr 9:60,726,809...60,918,139 		JBrowse link
G DAZAP2 DAZ associated protein 2 enables IEA Ensembl GO_REF:0000107 NCBI chr27:3,617,346...3,621,592
Ensembl chr27:3,615,726...3,621,587 		JBrowse link
G DDX3X DEAD-box helicase 3 X-linked enables IEA Ensembl GO_REF:0000107 NCBI chr  X:35,759,367...35,789,759
Ensembl chr  X:35,759,416...35,789,774 		JBrowse link
G DELE1 DAP3 binding cell death enhancer 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 2:36,865,275...36,880,304
Ensembl chr 2:36,865,289...36,879,840 		JBrowse link
G ETAA1 ETAA1 activator of ATR kinase enables IEA Ensembl GO_REF:0000107 NCBI chr10:66,631,411...66,644,753
Ensembl chr10:66,631,544...66,643,728 		JBrowse link
G FAM20A FAM20A golgi associated secretory pathway pseudokinase enables IEA Ensembl GO_REF:0000107 NCBI chr 9:15,205,887...15,218,873
Ensembl chr 9:15,207,300...15,230,447 		JBrowse link
G FERMT2 FERM domain containing kindlin 2 enables IEA Ensembl GO_REF:0000107 NCBI chr 8:29,083,538...29,135,915
Ensembl chr 8:29,084,531...29,133,391 		JBrowse link
G GCN1 GCN1 activator of EIF2AK4 enables IEA Ensembl GO_REF:0000107 NCBI chr26:16,087,380...16,146,865
Ensembl chr26:16,087,382...16,146,813 		JBrowse link
G GDF2 growth differentiation factor 2 enables IEA Ensembl GO_REF:0000107 NCBI chr 4:34,996,767...35,001,094
Ensembl chr 4:34,997,579...35,001,203 		JBrowse link
G IGF1 insulin like growth factor 1 enables ISO PMID:17023532 BHF-UCL PMID:17023532 RGD:1600072 NCBI chr15:41,203,320...41,275,964
Ensembl chr15:41,202,518...41,275,794 		JBrowse link
G IGF2 insulin like growth factor 2 enables ISO (PMID:20032056) BHF-UCL PMID:20032056 NCBI chr18:46,294,036...46,311,982
Ensembl chr18:46,294,019...46,311,982 		JBrowse link
G IQGAP1 IQ motif containing GTPase activating protein 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 3:53,683,869...53,791,136
Ensembl chr 3:53,683,791...53,792,186 		JBrowse link
G LGALS9 galectin 9 enables ISO (PMID:25065622) UniProt PMID:25065622 NCBI chr 9:42,154,613...42,170,423
Ensembl chr 9:42,154,702...42,170,391 		JBrowse link
G LOC481473 immunity-related GTPase family M protein enables ISO (PMID:28389568)
(PMID:25891078)		 UniProt PMID:25891078 PMID:28389568 NCBI chr11:793,416...795,373
Ensembl chr11:793,424...794,617 		JBrowse link
G LTF lactotransferrin enables IEA Ensembl GO_REF:0000107 NCBI chr20:42,231,994...42,263,202
Ensembl chr20:42,231,994...42,263,202 		JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 enables IEA Ensembl GO_REF:0000107 NCBI chr30:30,683,192...30,760,479
Ensembl chr30:30,683,107...30,760,479 		JBrowse link
G MAP2K2 mitogen-activated protein kinase kinase 2 enables ISO (PMID:8388392) UniProt PMID:8388392 NCBI chr20:55,465,460...55,487,629
Ensembl chr20:55,465,212...55,487,641 		JBrowse link
G MAP2K2 mitogen-activated protein kinase kinase 2 enables IEA Ensembl GO_REF:0000107
G MAP3K12 mitogen-activated protein kinase kinase kinase 12 enables IEA Ensembl GO_REF:0000107 NCBI chr27:1,721,484...1,736,204
Ensembl chr27:1,726,310...1,734,955 		JBrowse link
G MAP3K13 mitogen-activated protein kinase kinase kinase 13 enables IEA Ensembl GO_REF:0000107 NCBI chr34:18,081,158...18,252,800
Ensembl chr34:18,083,595...18,247,367 		JBrowse link
G MLST8 MTOR associated protein, LST8 homolog enables IEA Ensembl GO_REF:0000107 NCBI chr 6:38,759,713...38,765,556
Ensembl chr 6:38,762,103...38,765,488 		JBrowse link
G MOB1A MOB kinase activator 1A enables IEA Ensembl GO_REF:0000107 NCBI chr17:48,915,300...48,936,522
Ensembl chr17:48,915,346...48,933,303 		JBrowse link
G MOB1B MOB kinase activator 1B enables IEA Ensembl GO_REF:0000107 NCBI chr13:60,145,168...60,197,916
Ensembl chr13:60,145,366...60,195,463 		JBrowse link
G MTCP1 mature T cell proliferation 1 enables IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chr  X:123,071,076...123,080,695
Ensembl chr  X:123,074,956...123,080,793 		JBrowse link
G NBN nibrin enables IEA Ensembl GO_REF:0000107 NCBI chr29:35,416,093...35,477,569
Ensembl chr29:35,416,093...35,477,563 		JBrowse link
G P2RX7 purinergic receptor P2X 7 ISO Akt (protein kinase B); Ser473, Thr308 RGD PMID:15023862 RGD:1642719 NCBI chr26:7,928,863...7,983,956
Ensembl chr26:7,940,985...7,983,740 		JBrowse link
G PARP16 poly(ADP-ribose) polymerase family member 16 enables IEA Ensembl GO_REF:0000107 NCBI chr30:29,626,675...29,649,992
Ensembl chr30:29,573,184...29,650,883 		JBrowse link
G PIM1 Pim-1 proto-oncogene, serine/threonine kinase enables ISO (PMID:16186805) UniProt PMID:16186805 NCBI chr12:6,213,504...6,217,933
Ensembl chr12:6,211,867...6,217,933 		JBrowse link
G RAD50 RAD50 double strand break repair protein enables IEA Ensembl GO_REF:0000107 NCBI chr11:20,836,863...20,928,930
Ensembl chr11:20,836,879...20,928,819 		JBrowse link
G RHEB Ras homolog, mTORC1 binding enables IEA Ensembl GO_REF:0000107 NCBI chr16:15,439,910...15,483,489
Ensembl chr16:15,434,111...15,483,419 		JBrowse link
G RICTOR RPTOR independent companion of MTOR complex 2 enables IEA Ensembl GO_REF:0000107 NCBI chr 4:69,903,393...70,013,168
Ensembl chr 4:69,936,379...70,010,566 		JBrowse link
G SAV1 salvador family WW domain containing protein 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 8:27,034,606...27,061,926
Ensembl chr 8:27,022,628...27,062,611 		JBrowse link
G SLC27A1 solute carrier family 27 member 1 enables IEA Ensembl GO_REF:0000107 NCBI chr20:45,309,094...45,341,101
Ensembl chr20:45,310,088...45,340,230 		JBrowse link
G SPRY2 sprouty RTK signaling antagonist 2 enables IEA Ensembl GO_REF:0000107 NCBI chr22:33,366,139...33,371,102
Ensembl chr22:33,366,931...33,367,878 		JBrowse link
G STRADA STE20 related adaptor alpha enables IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chr 9:11,684,905...11,712,515
Ensembl chr 9:11,684,663...11,712,432 		JBrowse link
G STRADB STE20 related adaptor beta enables IEA InterPro GO_REF:0000002 NCBI chr37:10,521,643...10,557,611
Ensembl chr37:10,521,574...10,557,231 		JBrowse link
G TAB1 TGF-beta activated kinase 1 (MAP3K7) binding protein 1 enables IEA Ensembl GO_REF:0000107 NCBI chr10:25,623,381...25,657,630
Ensembl chr10:25,623,940...25,657,543 		JBrowse link
G TAOK1 TAO kinase 1 enables ISO PMID:14517247 ARUK-UCL PMID:14517247 RGD:8553906 NCBI chr 9:43,501,752...43,660,077
Ensembl chr 9:43,559,708...43,651,377 		JBrowse link
G TCL1A TCL1 family AKT coactivator A enables IEA InterPro GO_REF:0000002
G TCL1B TCL1 family AKT coactivator B enables IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr 8:64,497,560...64,500,412
Ensembl chr 8:64,497,560...64,500,412 		JBrowse link
G TGFB1 transforming growth factor beta 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 1:112,629,476...112,643,885
Ensembl chr 1:112,621,633...112,643,885 		JBrowse link
G TOPBP1 DNA topoisomerase II binding protein 1 enables IEA Ensembl GO_REF:0000107 NCBI chr23:30,517,172...30,578,664
Ensembl chr23:30,516,125...30,578,108 		JBrowse link
cyclin-dependent protein serine/threonine kinase activator activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCNB1 cyclin B1 enables ISO (PMID:24746669) CAFA PMID:24746669 NCBI chr 2:54,256,957...54,264,749 JBrowse link
G CCND1 cyclin D1 enables ISO (PMID:19237565) UniProt PMID:19237565 NCBI chr18:48,501,905...48,509,684
Ensembl chr18:48,501,899...48,516,005 		JBrowse link
G CCND2 cyclin D2 enables IEA Ensembl GO_REF:0000107 NCBI chr27:40,563,306...40,593,362
Ensembl chr27:40,564,921...40,594,255 		JBrowse link
G CCND3 cyclin D3 enables IEA Ensembl GO_REF:0000107 NCBI chr12:10,593,786...10,688,304
Ensembl chr12:10,594,712...10,600,891 		JBrowse link
G CCNT1 cyclin T1 enables IEA Ensembl GO_REF:0000107 NCBI chr27:5,788,426...5,817,518
Ensembl chr27:5,788,785...5,817,043 		JBrowse link
G CDK5R1 cyclin dependent kinase 5 regulatory subunit 1 enables ISO
IEA		 RGD
InterPro
Ensembl		 PMID:8662984 GO_REF:0000002 GO_REF:0000107 RGD:632374 NCBI chr 9:40,481,111...40,502,689
Ensembl chr 9:40,501,646...40,502,569 		JBrowse link
G CDK5R2 cyclin dependent kinase 5 regulatory subunit 2 enables IEA InterPro GO_REF:0000002 NCBI chr37:25,528,934...25,535,795
Ensembl chr37:25,529,151...25,530,263 		JBrowse link
G MNAT1 MNAT1 component of CDK activating kinase enables IEA UniProt
InterPro		 GO_REF:0000002 GO_REF:0000104 NCBI chr 8:35,747,883...35,946,353
Ensembl chr 8:35,756,933...35,946,353 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 18610
    molecular function regulator activity 1941
      enzyme regulator activity 1184
        enzyme activator activity 522
          kinase activator activity 132
            protein kinase activator activity 122
              protein serine/threonine kinase activator activity 64
                cyclin-dependent protein serine/threonine kinase activator activity 8
                eukaryotic elongation factor-2 kinase activator activity 0
paths to the root