CCNT1 (cyclin T1) - Rat Genome Database

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Gene: CCNT1 (cyclin T1) Canis lupus familiaris
Analyze
Symbol: CCNT1
Name: cyclin T1
RGD ID: 12351635
Description: ENCODES a protein that exhibits 7SK snRNA binding (inferred); chromatin binding (inferred); cyclin-dependent protein serine/threonine kinase activator activity (inferred); INVOLVED IN response to xenobiotic stimulus (ortholog); PARTICIPATES IN RNA polymerase II transcription elongation pathway; ASSOCIATED WITH congestive heart failure (ortholog); Experimental Diabetes Mellitus (ortholog); FOUND IN nucleolus (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: cyclin-T1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1275,788,426 - 5,817,518 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl275,788,785 - 5,817,043 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2740,440,318 - 40,469,408 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0275,839,609 - 5,868,796 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl275,839,914 - 5,868,686 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1275,803,121 - 5,832,059 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0275,793,437 - 5,822,569 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02740,832,282 - 40,861,450 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
CCNT1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1275,788,426 - 5,817,518 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl275,788,785 - 5,817,043 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2740,440,318 - 40,469,408 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0275,839,609 - 5,868,796 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl275,839,914 - 5,868,686 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1275,803,121 - 5,832,059 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0275,793,437 - 5,822,569 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02740,832,282 - 40,861,450 (-)NCBIUU_Cfam_GSD_1.0
CCNT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381248,688,458 - 48,716,707 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1248,688,458 - 48,716,998 (-)EnsemblGRCh38hg38GRCh38
GRCh371249,082,241 - 49,110,490 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361247,373,019 - 47,397,048 (-)NCBINCBI36Build 36hg18NCBI36
Build 341247,373,018 - 47,397,048NCBI
Celera1247,882,748 - 47,906,759 (-)NCBICelera
Cytogenetic Map12q13.11-q13.12NCBI
HuRef1246,116,314 - 46,144,840 (-)NCBIHuRef
CHM1_11249,048,056 - 49,076,621 (-)NCBICHM1_1
T2T-CHM13v2.01248,650,484 - 48,678,733 (-)NCBIT2T-CHM13v2.0
Ccnt1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391598,436,570 - 98,468,340 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1598,436,570 - 98,468,804 (-)EnsemblGRCm39 Ensembl
GRCm381598,538,690 - 98,567,736 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1598,538,689 - 98,570,923 (-)EnsemblGRCm38mm10GRCm38
MGSCv371598,373,642 - 98,398,067 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361598,371,245 - 98,395,670 (-)NCBIMGSCv36mm8
Celera15100,690,667 - 100,714,825 (-)NCBICelera
Cytogenetic Map15F1NCBI
cM Map1554.54NCBI
Ccnt1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87131,566,176 - 131,596,988 (-)NCBIGRCr8
mRatBN7.27129,687,146 - 129,718,080 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7129,691,209 - 129,717,871 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7131,499,023 - 131,525,200 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07133,724,573 - 133,750,750 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07133,637,075 - 133,663,250 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07140,215,052 - 140,245,958 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7140,219,551 - 140,245,723 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X114,723,098 - 114,752,376 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47137,288,635 - 137,314,809 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17137,365,064 - 137,391,433 (-)NCBI
Celera7126,182,570 - 126,208,635 (-)NCBICelera
Cytogenetic Map7q36NCBI
Ccnt1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555007,580,625 - 7,606,913 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555007,580,625 - 7,606,913 (-)NCBIChiLan1.0ChiLan1.0
CCNT1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21045,461,327 - 45,491,682 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11245,458,086 - 45,492,618 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01240,028,334 - 40,057,393 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11240,906,907 - 40,935,392 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1240,906,907 - 40,935,392 (+)Ensemblpanpan1.1panPan2
Ccnt1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494566,576,723 - 66,597,193 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365126,562,974 - 6,588,409 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365126,567,663 - 6,588,107 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CCNT1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl514,768,426 - 14,806,813 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1514,768,423 - 14,808,424 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2515,062,983 - 15,101,607 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CCNT1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11144,932,774 - 44,966,412 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1144,937,350 - 44,966,018 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037201,181,682 - 201,215,359 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ccnt1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248163,421,709 - 3,442,170 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248163,396,740 - 3,445,976 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CCNT1
381 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000014180   ⟹   ENSCAFP00000013117
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl275,788,785 - 5,817,043 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000080957   ⟹   ENSCAFP00000047493
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl275,788,785 - 5,817,043 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000081442   ⟹   ENSCAFP00000051904
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl275,788,785 - 5,805,606 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845044131   ⟹   ENSCAFP00845034580
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl275,839,914 - 5,868,686 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845044218   ⟹   ENSCAFP00845034655
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl275,839,914 - 5,856,819 (+)Ensembl
RefSeq Acc Id: XM_005636896   ⟹   XP_005636953
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1275,788,426 - 5,817,518 (+)NCBI
Dog10K_Boxer_Tasha2740,440,318 - 40,469,408 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038438321   ⟹   XP_038294249
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0275,839,609 - 5,868,796 (+)NCBI
RefSeq Acc Id: XM_038438322   ⟹   XP_038294250
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0275,839,609 - 5,868,796 (+)NCBI
RefSeq Acc Id: XM_038513032   ⟹   XP_038368960
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1275,803,121 - 5,832,059 (+)NCBI
RefSeq Acc Id: XM_038513033   ⟹   XP_038368961
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1275,803,121 - 5,832,059 (+)NCBI
RefSeq Acc Id: XM_038577507   ⟹   XP_038433435
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02740,832,282 - 40,861,450 (-)NCBI
RefSeq Acc Id: XM_038577508   ⟹   XP_038433436
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02740,832,282 - 40,861,450 (-)NCBI
RefSeq Acc Id: XM_038640794   ⟹   XP_038496722
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0275,793,437 - 5,822,569 (+)NCBI
RefSeq Acc Id: XM_038640795   ⟹   XP_038496723
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0275,793,437 - 5,822,569 (+)NCBI
RefSeq Acc Id: XM_543690   ⟹   XP_543690
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1275,788,426 - 5,817,518 (+)NCBI
Dog10K_Boxer_Tasha2740,440,318 - 40,469,408 (-)NCBI
Sequence:
RefSeq Acc Id: XP_543690   ⟸   XM_543690
- Peptide Label: isoform X1
- UniProtKB: A0A8C0TQZ3 (UniProtKB/TrEMBL),   A0A8I3PTL5 (UniProtKB/TrEMBL),   A0A8C0KMF4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005636953   ⟸   XM_005636896
- Peptide Label: isoform X2
- UniProtKB: A0A8C0KMF4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000013117   ⟸   ENSCAFT00000014180
Ensembl Acc Id: ENSCAFP00000047493   ⟸   ENSCAFT00000080957
Ensembl Acc Id: ENSCAFP00000051904   ⟸   ENSCAFT00000081442
RefSeq Acc Id: XP_038368960   ⟸   XM_038513032
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038368961   ⟸   XM_038513033
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038496722   ⟸   XM_038640794
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038496723   ⟸   XM_038640795
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038294249   ⟸   XM_038438321
- Peptide Label: isoform X1
- UniProtKB: A0A8C0TQZ3 (UniProtKB/TrEMBL),   A0A8I3PTL5 (UniProtKB/TrEMBL),   A0A8C0KMF4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038294250   ⟸   XM_038438322
- Peptide Label: isoform X2
- UniProtKB: A0A8C0KMF4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038433436   ⟸   XM_038577508
- Peptide Label: isoform X2
- UniProtKB: A0A8C0KMF4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038433435   ⟸   XM_038577507
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KMF4 (UniProtKB/TrEMBL),   A0A8C0TQZ3 (UniProtKB/TrEMBL),   A0A8I3PTL5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845034655   ⟸   ENSCAFT00845044218
Ensembl Acc Id: ENSCAFP00845034580   ⟸   ENSCAFT00845044131
Protein Domains
Cyclin-like

Promoters
RGD ID:13688118
Promoter ID:EPDNEW_C6185
Type:initiation region
Name:CCNT1_1
Description:cyclin T1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1275,788,747 - 5,788,807EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000008923 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030022585 UniProtKB/TrEMBL
  ENSCAFG00040025089 UniProtKB/TrEMBL
  ENSCAFG00845024989 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000014180.6 UniProtKB/TrEMBL
  ENSCAFT00000081442.2 UniProtKB/TrEMBL
  ENSCAFT00030041654.1 UniProtKB/TrEMBL
  ENSCAFT00030041701.1 UniProtKB/TrEMBL
  ENSCAFT00040046806.1 UniProtKB/TrEMBL
  ENSCAFT00040046827.1 UniProtKB/TrEMBL
  ENSCAFT00845044131 ENTREZGENE
  ENSCAFT00845044131.1 UniProtKB/TrEMBL
  ENSCAFT00845044218.1 UniProtKB/TrEMBL
Gene3D-CATH Cyclin-like UniProtKB/TrEMBL
InterPro Cyclin-like UniProtKB/TrEMBL
  Cyclin-like_sf UniProtKB/TrEMBL
  Cyclin/Ssn8 UniProtKB/TrEMBL
  CYCLIN_CCNT1_rpt2 UniProtKB/TrEMBL
  Cyclin_N UniProtKB/TrEMBL
NCBI Gene CCNT1 ENTREZGENE
PANTHER PTHR10026 UniProtKB/TrEMBL
  PTHR10026:SF42 UniProtKB/TrEMBL
Pfam Cyclin_N UniProtKB/TrEMBL
  CycT2-like_C UniProtKB/TrEMBL
SMART CYCLIN UniProtKB/TrEMBL
Superfamily-SCOP SSF47954 UniProtKB/TrEMBL
UniProt A0A8C0KMF4 ENTREZGENE
  A0A8C0PKF1_CANLF UniProtKB/TrEMBL
  A0A8C0TQZ3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3PTL5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3Q5Y0_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:38906 ENTREZGENE