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ONTOLOGY REPORT - ANNOTATIONS

Term:activation of Janus kinase activity
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Accession:GO:0042976 term browser browse the term
Definition:The process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it.
Synonyms:exact_synonym: activation of JAK protein;   activation of JAK protein by tyrosine phosphorylation
 narrow_synonym: activation of JAK1 kinase activity;   activation of JAK1 protein;   activation of JAK2 kinase activity;   activation of JAK2 protein;   tyrosine phosphorylation of JAK1 protein;   tyrosine phosphorylation of JAK2 protein
 broad_synonym: positive regulation of JAK protein activity by tyrosine phosphorylation
 related_synonym: tyrosine phosphorylation of JAK protein
 alt_id: GO:0010531;   GO:0042977


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activation of Janus kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtr1a angiotensin II receptor, type 1a IMP RGD PMID:9314843 RGD:6478796 NCBI chr17:34,383,397...34,435,523
Ensembl chr17:34,174,429...34,226,946 		JBrowse link
G Ghr growth hormone receptor IDA RGD PMID:11244571 RGD:1624962 NCBI chr 2:54,269,066...54,532,595
Ensembl chr 2:52,542,594...52,804,735 		JBrowse link
G Il3 interleukin 3 acts_upstream_of_or_within ISO (PMID:8378315) RGD PMID:8378315 NCBI chr10:38,906,460...38,908,810
Ensembl chr10:38,405,716...38,408,066 		JBrowse link
G Jak2 Janus kinase 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:20304997)		 UniProt
RGD		 PMID:20304997 GO_REF:0000024 NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Pibf1 progesterone immunomodulatory binding factor 1 involved_in ISO (PMID:16393965) RGD PMID:16393965 NCBI chr15:82,258,243...82,427,546
Ensembl chr15:75,850,624...76,019,712 		JBrowse link
G Prl3d4 prolactin family 3, subfamily D, member 4 IMP RGD PMID:8822264 RGD:1298822 NCBI chr17:37,325,804...37,332,641
Ensembl chr17:37,325,806...37,332,667 		JBrowse link
G Prlr prolactin receptor involved_in ISO (PMID:10585417) RGD PMID:10585417 NCBI chr 2:60,861,391...61,051,883
Ensembl chr 2:59,134,588...59,324,718 		JBrowse link
G Ptk2b protein tyrosine kinase 2 beta involved_in IMP
ISO		 (PMID:8670418) RGD PMID:8670418 PMID:11818507 RGD:633057 NCBI chr15:44,536,275...44,656,754
Ensembl chr15:40,360,723...40,481,282 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20553
    cellular process 19543
      signal transduction 7262
        positive regulation of signal transduction 1752
          positive regulation of receptor signaling pathway via STAT 75
            positive regulation of receptor signaling pathway via JAK-STAT 66
              activation of Janus kinase activity 8
Path 2
Term Annotations click to browse term
  biological_process 20553
    biological regulation 13833
      regulation of biological process 13387
        regulation of cellular process 13023
          regulation of metabolic process 6832
            regulation of macromolecule metabolic process 6296
              regulation of protein metabolic process 2007
                regulation of protein modification process 1084
                  regulation of protein phosphorylation 826
                    positive regulation of protein phosphorylation 518
                      positive regulation of protein kinase activity 276
                        activation of protein kinase activity 69
                          activation of Janus kinase activity 8
paths to the root