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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of receptor signaling pathway via STAT
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Accession:GO:1904894 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of receptor signaling pathway via STAT.
Synonyms:exact_synonym: positive regulation of STAT signalling pathway;   positive regulation of kinase activated-STAT cascade;   positive regulation of kinase-STAT cascade;   up regulation of STAT cascade;   up regulation of STAT signalling pathway;   up regulation of kinase activated-STAT cascade;   up regulation of kinase-STAT cascade;   upregulation of STAT cascade;   upregulation of STAT signalling pathway;   upregulation of kinase activated-STAT cascade;   upregulation of kinase-STAT cascade
 narrow_synonym: activation of STAT cascade;   activation of STAT signalling pathway;   activation of kinase activated-STAT cascade;   activation of kinase-STAT cascade


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positive regulation of receptor signaling pathway via STAT term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crlf2 cytokine receptor-like factor 2 involved_in ISO (PMID:11418668) RGD PMID:11418668 NCBI chr14:1,456,843...1,461,543
Ensembl chr14:1,456,844...1,461,543
JBrowse link
G Il6 interleukin 6 acts_upstream_of
involved_in
ISO RNAcentral:URS000000B1C9_9606|RNAcentral:URS00005A4DCF_9606 (PMID:30670152)
(MGI:84432|PMID:8910279)
RGD PMID:8910279 PMID:30670152 MGI:84432 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Il7r interleukin 7 receptor involved_in ISO (PMID:11418668) RGD PMID:11418668
G Jak1 Janus kinase 1 acts_upstream_of_or_within ISO MGI:2176165|MGI:5688302 (MGI:5796184|PMID:27671227) RGD PMID:27671227 MGI:5796184 NCBI chr 5:119,982,503...120,091,452
Ensembl chr 5:119,982,943...120,083,904
JBrowse link
G Mgat5 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase involved_in ISO (PMID:24846175) RGD PMID:24846175 NCBI chr13:43,850,744...44,157,860
Ensembl chr13:43,850,751...44,157,924
JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO (PMID:28467929) RGD PMID:28467929 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tslp thymic stromal lymphopoietin involved_in
NOT|involved_in
ISO (PMID:11418668)
(PMID:24850429)
RGD PMID:11418668 PMID:24850429 NCBI chr18:25,613,601...25,618,066
Ensembl chr18:25,613,831...25,617,361
JBrowse link
activation of Janus kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtr1a angiotensin II receptor, type 1a IMP RGD PMID:9314843 RGD:6478796 NCBI chr17:35,907,102...35,958,136
Ensembl chr17:35,907,108...35,958,077
JBrowse link
G Ghr growth hormone receptor IDA RGD PMID:11244571 RGD:1624962 NCBI chr 2:53,149,225...53,413,954
Ensembl chr 2:53,150,370...53,413,638
JBrowse link
G Il3 interleukin 3 acts_upstream_of_or_within ISO (MGI:63384|PMID:8378315) RGD PMID:8378315 MGI:63384 NCBI chr10:39,620,535...39,622,973
Ensembl chr10:39,620,563...39,622,973
JBrowse link
G Il4 interleukin 4 involved_in ISO
IBA
UniProtKB:P08575 (PMID:12574355)
PMID:21873635
RGD PMID:12574355, PMID:21873635 RGD:13792537 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Jak2 Janus kinase 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:4457458|PMID:20304997)
UniProt
RGD
PMID:20304997 GO_REF:0000024 MGI:4457458 NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509
JBrowse link
G Pibf1 progesterone immunomodulatory binding factor 1 involved_in ISO (PMID:16393965) RGD PMID:16393965 NCBI chr15:83,494,110...83,663,202
Ensembl chr15:83,495,377...83,663,143
JBrowse link
G Prl3d4 prolactin family 3, subfamily d, member 4 IMP RGD PMID:8822264 RGD:1298822 NCBI chr17:39,271,883...39,278,716
Ensembl chr17:39,272,004...39,278,695
Ensembl chr17:39,272,004...39,278,695
JBrowse link
G Prlr prolactin receptor involved_in IEA
ISO
GO_REF:0000107
(PMID:10585417)
Ensembl
RGD
PMID:10585417 GO_REF:0000107 NCBI chr 2:60,131,410...60,325,686
Ensembl chr 2:60,131,776...60,325,692
JBrowse link
G Ptk2b protein tyrosine kinase 2 beta involved_in IMP
ISO
(PMID:8670418) RGD PMID:8670418, PMID:11818507 RGD:633057 NCBI chr15:42,827,306...42,947,796
Ensembl chr15:42,827,310...42,947,656
JBrowse link
negative regulation of activation of Janus kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd300a Cd300a molecule involved_in ISO (PMID:16254138) RGD PMID:16254138 NCBI chr10:103,437,978...103,451,170
Ensembl chr10:103,438,303...103,450,947
JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha IDA RGD PMID:16584384 RGD:1625011 NCBI chr 3:159,902,441...159,965,003
Ensembl chr 3:159,902,441...159,965,003
JBrowse link
positive regulation of activation of Janus kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen involved_in ISO (PMID:15153556) RGD PMID:15153556 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Gh1 growth hormone 1 involved_in ISO (PMID:12552091) RGD PMID:12552091 NCBI chr10:94,486,204...94,488,181
Ensembl chr10:94,486,205...94,488,180
JBrowse link
G Il12b interleukin 12B involved_in ISO (PMID:12023369) RGD PMID:12023369 NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085
JBrowse link
G Il23a interleukin 23 subunit alpha involved_in ISO
IBA
(PMID:12023369)
PMID:21873635
RGD PMID:12023369, PMID:21873635 RGD:13792537 NCBI chr 7:2,710,609...2,712,723
Ensembl chr 7:2,710,609...2,712,723
JBrowse link
G Il6r interleukin 6 receptor involved_in IBA
ISO
PMID:21873635
(PMID:12419823)
RGD PMID:12419823, PMID:21873635 RGD:13792537 NCBI chr 2:189,196,180...189,255,987
Ensembl chr 2:189,205,701...189,254,628
JBrowse link
positive regulation of receptor signaling pathway via JAK-STAT term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07027730.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr17:42,695,322...42,699,092 JBrowse link
G Adipor1 adiponectin receptor 1 IMP RGD PMID:18394428 RGD:2317907 NCBI chr13:51,240,470...51,260,233
Ensembl chr13:51,240,911...51,260,228
JBrowse link
G Agap2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 acts_upstream_of_or_within ISO MGI:4439325 (MGI:4438668|PMID:20075866) RGD PMID:20075866 MGI:4438668 NCBI chr 7:70,360,199...70,377,422
Ensembl chr 7:70,364,813...70,377,422
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B IMP RGD PMID:15746188 RGD:1626095 NCBI chr 4:61,706,866...61,720,959
Ensembl chr 4:61,706,864...61,720,956
JBrowse link
G Cenpj centromere protein J acts_upstream_of_or_within ISO (PMID:12198240) RGD PMID:12198240 NCBI chr15:36,745,672...36,809,228
Ensembl chr15:36,746,088...36,798,814
JBrowse link
G Cntf ciliary neurotrophic factor IDA RGD PMID:15574731 RGD:1626128 NCBI chr 1:229,599,009...229,601,032
Ensembl chr 1:229,599,009...229,601,032
JBrowse link
G Crlf3 cytokine receptor-like factor 3 involved_in ISO (PMID:19427400) RGD PMID:19427400 NCBI chr10:67,383,664...67,401,836
Ensembl chr10:67,383,900...67,401,836
JBrowse link
G Cxcl6 C-X-C motif chemokine ligand 6 IDA RGD PMID:21114767 RGD:5135266 NCBI chr14:18,860,201...18,920,839
Ensembl chr14:18,860,264...18,862,407
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:5492227|PMID:23568032)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:23568032 GO_REF:0000024 GO_REF:0000107 MGI:5492227 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:3689173|PMID:16837552)
(PMID:15534001)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:15534001 PMID:16837552 GO_REF:0000024 GO_REF:0000107 MGI:3689173 NCBI chr 9:75,021,790...76,178,936
Ensembl chr 9:75,021,790...75,528,644
JBrowse link
G F2r coagulation factor II (thrombin) receptor involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 2:26,118,760...26,135,340
Ensembl chr 2:26,118,760...26,135,340
JBrowse link
G Gh1 growth hormone 1 involved_in IBA
ISO
PMID:21873635
(PMID:8923468)
RGD PMID:8923468, PMID:21873635 RGD:13792537 NCBI chr10:94,486,204...94,488,181
Ensembl chr10:94,486,205...94,488,180
JBrowse link
G Ghr growth hormone receptor involved_in IDA
IBA
IMP
PMID:21873635 RGD
GO_Central
PMID:11064147, PMID:21873635, PMID:10976913 RGD:1624963, RGD:13792537, RGD:1624964 NCBI chr 2:53,149,225...53,413,954
Ensembl chr 2:53,150,370...53,413,638
JBrowse link
G Hes1 hes family bHLH transcription factor 1 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:5284803|PMID:15156153)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:15156153 GO_REF:0000024 GO_REF:0000107 MGI:5284803 NCBI chr11:74,312,837...74,315,249
Ensembl chr11:74,312,806...74,315,248
JBrowse link
G Hes5 hes family bHLH transcription factor 5 involved_in ISS
ISO
GO_REF:0000024
(MGI:5284803|PMID:15156153)
UniProt
RGD
PMID:15156153 GO_REF:0000024 MGI:5284803 NCBI chr 5:172,364,421...172,365,188
Ensembl chr 5:172,364,421...172,365,188
JBrowse link
G Ifnl1 interferon, lambda 1 involved_in ISO (PMID:12483210) RGD PMID:12483210 NCBI chr 1:85,252,103...85,253,635
Ensembl chr 1:85,252,103...85,253,635
JBrowse link
G Il10 interleukin 10 involved_in ISO (PMID:16982608) RGD PMID:16982608 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il10ra interleukin 10 receptor subunit alpha involved_in ISO (PMID:16982608) RGD PMID:16982608 NCBI chr 8:49,558,062...49,573,891
Ensembl chr 8:49,560,035...49,573,742
JBrowse link
G Il10rb interleukin 10 receptor subunit beta involved_in ISO (PMID:16982608) RGD PMID:16982608 NCBI chr11:31,560,301...31,582,457
Ensembl chr11:31,560,530...31,582,457
JBrowse link
G Il4 interleukin 4 involved_in ISO (PMID:24280217) RGD PMID:24280217 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il5 interleukin 5 IMP RGD PMID:10867506 RGD:2303751 NCBI chr10:39,066,716...39,069,587
Ensembl chr10:39,066,716...39,069,587
JBrowse link
G Il6 interleukin 6 involved_in IDA
IBA
ISO
PMID:21873635
(PMID:12419823), (PMID:12552091), (PMID:17324931)
STAT3 phosphorylation
RGD PMID:12419823 PMID:12552091 PMID:17324931, PMID:16413512, PMID:21873635, PMID:15659221 RGD:1580483, RGD:13792537, RGD:1641883 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase involved_in IBA
ISO
PMID:21873635
(PMID:21135090)
RGD PMID:21135090, PMID:21873635 RGD:13792537 NCBI chr14:35,072,131...35,149,638
Ensembl chr14:35,072,108...35,149,610
JBrowse link
G Lep leptin involved_in IMP
ISO
ISS
IBA
(MGI:4889014|PMID:21234744), (MGI:5700303|PMID:16825198)
GO_REF:0000024
PMID:21873635
(PMID:17344214)
RGD
UniProt
PMID:16825198 PMID:17344214 PMID:21234744, PMID:21250909, PMID:21873635 GO_REF:0000024 MGI:4889014 MGI:5700303, RGD:5128518, RGD:13792537 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G LOC103690150 prolactin-3D1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:39,721,952...39,730,983
Ensembl chr17:39,722,082...39,728,353
JBrowse link
G LOC684107 similar to placental prolactin-like protein O involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:38,919,078...38,928,447
Ensembl chr17:38,919,078...38,928,447
JBrowse link
G Notch1 notch receptor 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:5284803|PMID:15156153)
UniProt
RGD
PMID:15156153 GO_REF:0000024 MGI:5284803 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025
JBrowse link
G Prl prolactin involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:12552091)
MGI:102709 (MGI:3703676|PMID:12388746)
PMID:21873635
RGD PMID:12388746 PMID:12552091, PMID:21873635 MGI:3703676, RGD:13792537 NCBI chr17:39,814,236...39,824,299
Ensembl chr17:39,814,244...39,824,299
JBrowse link
G Prl2a1 Prolactin family 2, subfamily a, member 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:38,900,411...38,906,503
Ensembl chr17:38,900,412...38,906,503
JBrowse link
G Prl2b1 Prolactin family 2, subfamily b, member 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:39,542,058...39,549,080
Ensembl chr17:39,542,096...39,549,082
JBrowse link
G Prl2c1 Prolactin family 2, subfamily c, member 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:38,849,932...38,858,391
Ensembl chr17:38,849,932...38,858,331
JBrowse link
G Prl3a1 Prolactin family 3, subfamily a, member 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:42,723,745...42,740,021
Ensembl chr17:42,723,682...42,740,021
JBrowse link
G Prl3b1 Prolactin family 3, subfamily b, member 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:42,771,523...42,777,186
Ensembl chr17:42,771,526...42,777,186
JBrowse link
G Prl3c1 Prolactin family 3, subfamily c, member 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:42,812,517...42,818,305
Ensembl chr17:42,812,524...42,818,258
JBrowse link
G Prl3d1 Prolactin family 3, subfamily d, member 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:39,777,255...39,782,877
Ensembl chr17:39,777,301...39,782,860
JBrowse link
G Prl3d2 Prolactin family 3, subfamily d, member 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:42,849,469...42,855,496
Ensembl chr17:42,849,469...42,855,496
JBrowse link
G Prl3d4 prolactin family 3, subfamily d, member 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:39,271,883...39,278,716
Ensembl chr17:39,272,004...39,278,695
Ensembl chr17:39,272,004...39,278,695
JBrowse link
G Prl4a1 prolactin family 4, subfamily a, member 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:38,710,401...38,718,343
Ensembl chr17:38,710,432...38,718,317
JBrowse link
G Prl5a1 prolactin family 5, subfamily a, member 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:38,323,633...38,331,051
Ensembl chr17:38,323,674...38,330,944
JBrowse link
G Prl5a2 prolactin family 5, subfamily a, member 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:38,456,016...38,462,358
Ensembl chr17:38,456,073...38,462,352
JBrowse link
G Prl6a1 prolactin family 6, subfamily a, member 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:42,705,730...42,710,574
Ensembl chr17:42,705,734...42,710,574
JBrowse link
G Prl7a3 prolactin family 7, subfamily a, member 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:39,032,661...39,045,326
Ensembl chr17:39,032,661...39,045,326
JBrowse link
G Prl7a4 prolactin family 7, subfamily a, member 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:39,095,463...39,104,519
Ensembl chr17:39,095,459...39,104,519
JBrowse link
G Prl7b1 prolactin family 7, subfamily b, member 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:39,153,431...39,161,644
Ensembl chr17:39,153,465...39,161,641
JBrowse link
G Prl7d1 prolactin family 7, subfamily d, member 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:38,993,183...38,999,651
Ensembl chr17:38,929,045...38,999,652
JBrowse link
G Prl8a2 prolactin family 8, subfamily a, member 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:39,563,383...39,575,777
Ensembl chr17:39,563,387...39,575,720
JBrowse link
G Prl8a3 prolactin family 8, subfamily a, member 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:39,455,865...39,463,715
Ensembl chr17:39,455,908...39,462,629
JBrowse link
G Prl8a4 prolactin family 8, subfamily a, member 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:39,376,040...39,382,128
Ensembl chr17:39,188,311...39,463,715
Ensembl chr17:39,188,311...39,463,715
JBrowse link
G Prl8a5 prolactin family 8, subfamily a, member 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:39,411,716...39,417,929
Ensembl chr17:39,188,311...39,463,715
JBrowse link
G Prl8a7 prolactin family 8, subfamily a, member 7 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:39,509,516...39,515,418
Ensembl chr17:39,509,516...39,515,412
JBrowse link
G Prl8a9 prolactin family 8, subfamily a, member 9 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:39,241,133...39,246,941
Ensembl chr17:39,241,133...39,246,940
JBrowse link
G Stra6 signaling receptor and transporter of retinol STRA6 acts_upstream_of_or_within ISO MGI:5490784 (MGI:5527038|PMID:23839944) RGD PMID:23839944 MGI:5527038 NCBI chr 8:62,925,364...62,944,438
Ensembl chr 8:62,925,357...62,944,437
JBrowse link
G Tnf tumor necrosis factor involved_in IDA PMID:29702085 ARUK-UCL PMID:29702085 RGD:13800534 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
regulation of activation of Janus kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Socs1 suppressor of cytokine signaling 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2656917 (MGI:5013875|PMID:21606371)
Ensembl
RGD
PMID:21606371 GO_REF:0000107 MGI:5013875 NCBI chr10:4,956,795...4,958,472
Ensembl chr10:4,957,326...4,958,461
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19491
    cellular process 18344
      signal transduction 6881
        positive regulation of signal transduction 1597
          positive regulation of receptor signaling pathway via STAT 72
            positive regulation of receptor signaling pathway via JAK-STAT + 66
Path 2
Term Annotations click to browse term
  biological_process 19491
    biological regulation 13514
      regulation of biological process 12772
        regulation of cellular process 12273
          signal transduction 6881
            cell surface receptor signaling pathway 2774
              receptor signaling pathway via STAT 188
                regulation of receptor signaling pathway via STAT 128
                  positive regulation of receptor signaling pathway via STAT 72
                    positive regulation of receptor signaling pathway via JAK-STAT + 66
paths to the root